Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
di(p-propylbenzylidene) alkyl sorbitol
473-780-7 - Active Full Joint Tonnage data confidential 14-06-2016 View substance registered dossier
di(p-propylbenzylidene) alkyl sorbitol
473-780-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Di(morpholin-4-yl) disulphide
203-103-0 103-34-4 Active Full Joint ≥ 100 to < 1 000 tonnes 24-04-2019 View substance registered dossier
Di(isooctadecanoic) acid, diester with oxydi(propanediol)
267-821-6 67938-21-0 Active Full Joint ≥ 100 to < 1 000 tonnes 26-07-2021 View substance registered dossier
Di(carbazamidine) sulphate
213-628-7 996-19-0 Active Intermediate Joint Intermediate use only 27-08-2021 View substance registered dossier
di(C9-11-alkyl) cyclohexane-1,4-dicarboxylate
428-870-0 1379678-91-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Di(benzothiazol-2-yl) disulphide
204-424-9 120-78-5 Active Full Joint ≥ 10 000 to < 100 000 tonnes 29-09-2020 View substance registered dossier
DHBA-NHS
444-790-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dextransucrase
821-951-5 9032-14-8 Active Full Joint ≥ 10 to < 100 tonnes 23-03-2018 View substance registered dossier
Dexpanthenol
201-327-3 81-13-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 13-04-2022 View substance registered dossier
Dexamphetamine
200-112-1 51-64-9 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
Dexamethasone 21-acetate
214-646-8 1177-87-3 Active Intermediate Joint Intermediate use only 28-11-2017 View substance registered dossier
Dexamethasone 21-(disodium phosphate)
219-243-0 2392-39-4 Active Intermediate Joint Intermediate use only 14-11-2017 View substance registered dossier
Dexamethasone
200-003-9 50-02-2 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Deuterium oxide
232-148-9 7789-20-0 Active Full Joint ≥ 1 to < 10 tonnes 12-04-2021 View substance registered dossier
Deuterium
231-952-7 7782-39-0 Active Full Joint ≥ 0 to < 10 tonnes 22-06-2020 View substance registered dossier
DETR3
420-080-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
destillation fraction of chlorosilanes
700-717-5 - Cease Manufacture Full Individual Cease manufacture 09-11-2012 View substance registered dossier
DESOXYMULUNDOCANDIN
434-490-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Desmopan DP 9985A FR
465-920-0 - Active NONS Individual Tonnage data confidential 30-09-2010 View substance registered dossier
Desipramine hydrochloride
200-373-1 58-28-6 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
Desipramine
200-040-0 50-47-5 Active Intermediate Joint Intermediate use only 08-02-2018 View substance registered dossier
DEPS
423-890-6 70155-90-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
DEPESA
421-980-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Deoxybenzoin
207-193-2 451-40-1 Active Intermediate Joint Intermediate use only 27-09-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - di(p-propylbenzylidene) alkyl sorbitol 473-780-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active di(p-propylbenzylidene) alkyl sorbitol 473-780-7 - - View substance registered dossier
VIBIPLAST s.r.l. Via Modigliani 12-19 20022 Castano Primo (MI) Italy Italy Active Di(morpholin-4-yl) disulphide 203-103-0 103-34-4 - View substance registered dossier
MLPC International 209 avenue Charles Despiau 40370 Rion-les-Landes France France Active Di(morpholin-4-yl) disulphide 203-103-0 103-34-4 2011; 2012; 2014; 2018 View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active Di(morpholin-4-yl) disulphide 203-103-0 103-34-4 - View substance registered dossier
Clariant Ibérica Producción S.A. Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain Spain Active Di(isooctadecanoic) acid, diester with oxydi(propanediol) 267-821-6 67938-21-0 2015 View substance registered dossier
WSP Deutschland A.G. (OR3) Dingolfinger Straße 1-15 81673 München Germany Germany Active Di(isooctadecanoic) acid, diester with oxydi(propanediol) 267-821-6 67938-21-0 2021 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active Di(carbazamidine) sulphate 213-628-7 996-19-0 2021 View substance registered dossier
EIGENMANN & VERONELLI S.p.A. via della Mosa, 6 20017 Rho (MI) Italy Italy Active Di(carbazamidine) sulphate 213-628-7 996-19-0 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany No longer Valid Di(carbazamidine) sulphate 213-628-7 996-19-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active di(C9-11-alkyl) cyclohexane-1,4-dicarboxylate 428-870-0 1379678-91-7 - View substance registered dossier
Manufacture Française des Pneumatiques Michelin (OR US) Place des Carmes Déchaux 63040 Clemront Ferrand France France Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
General Química S.A.U. Carretera Miranda-Puentelarrá km 5 01213 Comunión Alava Spain Spain Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 2012; 2017; 2020 View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED 306 The Capel Building, Mary's Abbey, Dublin 7, Ireland Dublin 7 Dublin Ireland Ireland Cease Manufacture Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 2018 View substance registered dossier
REACH24H CONSULTING GROUP (acts as the OR for Hebi Uhoo Rubber Chemicals Co., Ltd.) Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 2012 View substance registered dossier
REACH24H CONSULTING GROUP (acts as the OR for Willing New Materials Technology Co., Ltd.) Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 2017 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
VIBIPLAST s.r.l. Via Modigliani 12-19 20022 Castano Primo (MI) Italy Italy Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
Manufacture Française des Pneumatiques Michelin (OR CAN) Place des Carmes Déchaux 63040 Clermont Ferrand France France Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
INTERTEK FRANCE ZAC Ecoparc II 27400 HEUDEBOUVILLE France France Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 - View substance registered dossier
LANXESS N.V. Scheldelaan 420 Haven 507 2040 Antwerpen Belgium Belgium Active Di(benzothiazol-2-yl) disulphide 204-424-9 120-78-5 2012; 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active DHBA-NHS 444-790-9 - - View substance registered dossier
Genencor International B.V. - OR-US Willem Einthovenstraat 4 2342 BH Oegstgeest Netherlands Netherlands Active Dextransucrase 821-951-5 9032-14-8 - View substance registered dossier
Genencor International B.V. - OR-CN Willem Einthovenstraat 4 2342 BH Oegstgeest​ Netherlands Netherlands Active Dextransucrase 821-951-5 9032-14-8 - View substance registered dossier
Genencor International Oy Tiilikantie 15 FI-42300 Jämsänkoski Finland Finland Active Dextransucrase 821-951-5 9032-14-8 - View substance registered dossier
Genencor International BV - Belgium Komvest 43 8000 Brugge Belgium Belgium Active Dextransucrase 821-951-5 9032-14-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Dexpanthenol 201-327-3 81-13-0 2013; 2014; 2019 View substance registered dossier
TÜV SÜD Industrie Service GmbH Westendstr. 199 IS-CMS-MUC 80686 Munich Germany Germany Cease Manufacture Dexpanthenol 201-327-3 81-13-0 2016 View substance registered dossier
SOPROCOS ZI Le Moulin de tous vents GAUCHY - BP294 02106 SAINT QUENTIN Cedex France France Active Dexpanthenol 201-327-3 81-13-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Hangzhou Xinfu Science & Technology Co., Ltd.) Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Dexpanthenol 201-327-3 81-13-0 2016; 2017 View substance registered dossier
PRODUCTOS CAPILARES L'OREAL S.A. Calle Lopez Bravo n°78 Poligono Industrial Villalonquéjar 09001 BURGOS Spain Spain Active Dexpanthenol 201-327-3 81-13-0 2019 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (AHB-Anhui Huaheng Biotechnology Co., Ltd) Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Dexpanthenol 201-327-3 81-13-0 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Dexpanthenol 201-327-3 81-13-0 2018 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Dexpanthenol 201-327-3 81-13-0 2019 View substance registered dossier
Fenchem Biochemie GmbH Mathias-Brüggen-Str. 146 50829 Köln Germany Germany Active Dexpanthenol 201-327-3 81-13-0 - View substance registered dossier
DSM Nutritional Products GmbH-OR18 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active Dexpanthenol 201-327-3 81-13-0 2013; 2018; 2019 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Jiangxi Brother Pharmaceutical Co., Ltd.) Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Dexpanthenol 201-327-3 81-13-0 - View substance registered dossier
Artec Europe BV Vivaldistraat 3 7132 AG Lichtenvoorde Netherlands Netherlands Active Dexpanthenol 201-327-3 81-13-0 - View substance registered dossier
SYNTHEXIM 1 Quai d'Amérique 62 100 calais France France Active Dexamphetamine 200-112-1 51-64-9 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Dexamethasone 21-acetate 214-646-8 1177-87-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Dexamethasone 21-(disodium phosphate) 219-243-0 2392-39-4 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active Dexamethasone 200-003-9 50-02-2 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Dexamethasone 200-003-9 50-02-2 2021; 2022 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Deuterium oxide 232-148-9 7789-20-0 2021 View substance registered dossier
knoell Germany - OR - E13 Konrad-Zuse-Ring 25 68163 Mannheim Germany Germany Active Deuterium oxide 232-148-9 7789-20-0 - View substance registered dossier
EURISO-TOP Parc des Algorithmes Bât. Homère 91194 SAINT-AUBIN France France Active Deuterium oxide 232-148-9 7789-20-0 - View substance registered dossier
Linde GmbH Gases Division Seitnerstrasse 70 DE-82049 Pullach Germany Germany Active Deuterium 231-952-7 7782-39-0 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active DETR3 420-080-4 - - View substance registered dossier
Momentive Performance Materials GmbH Chempark Building V7 51368 Leverkusen NRW Germany Germany Cease Manufacture destillation fraction of chlorosilanes 700-717-5 - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active DESOXYMULUNDOCANDIN 434-490-6 - - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active Desmopan DP 9985A FR 465-920-0 - 2010 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Desipramine hydrochloride 200-373-1 58-28-6 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Desipramine 200-040-0 50-47-5 - View substance registered dossier
- - - - DEPS 423-890-6 70155-90-7 - View substance registered dossier
- - - - DEPESA 421-980-1 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active Deoxybenzoin 207-193-2 451-40-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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