Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4-hydroxyphenyl-alpha-D-glucopyranoside
ALPHARBUTIN
440-470-8 84380-01-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer
433-660-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-mesyl-2-nitrotoluene
430-550-0 1671-49-4 Active NONS Joint Tonnage data confidential 12-01-2011 View substance registered dossier
4-methoxy-N,6-dimethyl-1,3,5-triazin-2-ylamine
2-METHOXY-4-METHYL-6-METHYLAMINO-1,3,5-TRIAZIN; DPX-L5296; L5296
401-360-5 5248-39-5 Active NONS Joint Tonnage data confidential 18-02-2011 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 104146-10-3 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide
425-860-8 125971-57-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-8-methylenetricyclo[3.3.1.13,7]dec-2-yl acetate
PRISMYLATE
406-560-6 122760-85-4 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-8-methylenetricyclo[3.3.1.13,7]decan-2-ol
PRISMANTOL
406-330-5 122760-84-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-N,N-bis(2-(((4-methylphenyl)sulfonyl)amino)ethyl)benzenesulfonamide
DIETHYLEN-TRIAMIN-TRITOSYLAT
413-300-5 56187-04-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-N-(methylsulfonyl)benzenesulfonamide
POWDERLINK (R) MTSI
415-040-8 14653-91-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine
467-100-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methylphenyl 4-methoxybenzoate
ME 10.1
439-300-5 58600-95-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-Octanol, 3-amino-
482-070-6 1001354-72-8 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]-
457-890-2 860399-11-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine
419-240-6 171054-89-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Penten-1-one, 1-phenyl-
402-310-5 3240-29-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl-
438-060-9 224031-70-3 Active NONS Joint Tonnage data confidential 15-12-2020 View substance registered dossier
4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl-
438-060-9 224031-70-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-phenylbut-1-ene
4-PHENYL-1-BUTENE; SQ 31,175; SQ31175
405-980-7 768-56-9 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)-
440-550-2 244021-01-0 Active NONS Joint Tonnage data confidential 24-06-2009 View substance registered dossier
4-Pyrimidinecarboxamide, 2-(1-amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-
465-070-0 518048-03-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)-
457-660-1 104797-47-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts.
466-670-5 - Active NONS Individual Tonnage data confidential 24-11-2010 View substance registered dossier
493 F
437-020-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4H-Indeno[4,5-d]-1,3-dioxole, 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl-
457-070-4 823178-41-2 Active NONS Joint Tonnage data confidential 09-09-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - 4-hydroxyphenyl-alpha-D-glucopyranoside 440-470-8 84380-01-8 - View substance registered dossier
- - - - 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany Germany Cease Manufacture 4-mesyl-2-nitrotoluene 430-550-0 1671-49-4 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. - - Active 4-mesyl-2-nitrotoluene 430-550-0 1671-49-4 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 4-mesyl-2-nitrotoluene 430-550-0 1671-49-4 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 4-mesyl-2-nitrotoluene 430-550-0 1671-49-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-mesyl-2-nitrotoluene 430-550-0 1671-49-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-methoxy-N,6-dimethyl-1,3,5-triazin-2-ylamine 401-360-5 5248-39-5 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Cease Manufacture 4-methoxy-N,6-dimethyl-1,3,5-triazin-2-ylamine 401-360-5 5248-39-5 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 104146-10-3 - View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 104146-10-3 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Cease Manufacture 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide 425-860-8 125971-57-5 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide 425-860-8 125971-57-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide 425-860-8 125971-57-5 - View substance registered dossier
- - - - 4-methyl-8-methylenetricyclo[3.3.1.13,7]dec-2-yl acetate 406-560-6 122760-85-4 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active 4-methyl-8-methylenetricyclo[3.3.1.13,7]dec-2-yl acetate 406-560-6 122760-85-4 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 4-methyl-8-methylenetricyclo[3.3.1.13,7]decan-2-ol 406-330-5 122760-84-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-methyl-N,N-bis(2-(((4-methylphenyl)sulfonyl)amino)ethyl)benzenesulfonamide 413-300-5 56187-04-3 - View substance registered dossier
Cytec Industries BV Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active 4-methyl-N-(methylsulfonyl)benzenesulfonamide 415-040-8 14653-91-9 - View substance registered dossier
- - - - 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
- - - - 4-methylphenyl 4-methoxybenzoate 439-300-5 58600-95-6 - View substance registered dossier
DOW BENELUX B.V. - OR2 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Cease Manufacture 4-Octanol, 3-amino- 482-070-6 1001354-72-8 2015 View substance registered dossier
- - - - 4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]- 457-890-2 860399-11-7 - View substance registered dossier
BASF plc Earl Road, P O Box 4 SK8 6QG Cheadle Hulme Cheshire United Kingdom United Kingdom No longer Valid 4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine 419-240-6 171054-89-0 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine 419-240-6 171054-89-0 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active 4-Penten-1-one, 1-phenyl- 402-310-5 3240-29-7 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active 4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl- 438-060-9 224031-70-3 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl- 438-060-9 224031-70-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-phenylbut-1-ene 405-980-7 768-56-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-phenylbut-1-ene 405-980-7 768-56-9 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture 4-phenylbut-1-ene 405-980-7 768-56-9 2017 View substance registered dossier
- - - - 4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)- 440-550-2 244021-01-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-Pyrimidinecarboxamide, 2-(1-amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo- 465-070-0 518048-03-8 - View substance registered dossier
SUANFARMA Italia SpA Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy Italy Active 4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)- 457-660-1 104797-47-9 - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom Active 4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts. 466-670-5 - 2010 View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Active 493 F 437-020-8 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 4H-Indeno[4,5-d]-1,3-dioxole, 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl- 457-070-4 823178-41-2 2012; 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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