Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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R,R-2-carboxy –[2-(2-propen-1-yl)-cyclopropyl] benzoate dicyclohexylamonium salt
944-401-7 - Active Intermediate Joint Intermediate use only 07-02-2017 View substance registered dossier
R-(+)-1-(1-naphthyl)ethylamine
223-425-5 3886-70-2 Active Intermediate Joint Intermediate use only 08-01-2018 View substance registered dossier
Raloxifene
686-786-1 84449-90-1 Active Intermediate Joint Intermediate use only 28-04-2022 View substance registered dossier
Ranitidine
266-332-5 66357-35-5 Active Intermediate Joint Intermediate use only 12-06-2017 View substance registered dossier
Rapamycin
610-965-5 53123-88-9 Cease Manufacture Intermediate Individual Cease manufacture 26-08-2014 View substance registered dossier
Rape oil, oxidized
305-871-3 95193-59-2 Active Intermediate Individual Intermediate use only 02-10-2012 View substance registered dossier
reaction and salt formation product of benzene-1,2-dicarboxylic acid and chlorine
923-003-7 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
Reaction mass 2-methylpenta-1,3-diene and 4-methylpenta-1,3-diene and 4-methylpent-4-en-2-ol
937-376-9 - Active Intermediate Individual Intermediate use only 06-11-2012 View substance registered dossier
Reaction mass E-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide and Z-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide
936-979-4 - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
Reaction mass E-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide and Z-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide
936-979-4 - Active Intermediate Individual Intermediate use only 12-11-2012 View substance registered dossier
Reaction mass of (+/-)-(S*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran and (1’S, 2R)-2-(1’, 2’-Dihydroxyethyl)-6-fluorochromane
948-018-6 - Active Intermediate Joint Intermediate use only 16-10-2018 View substance registered dossier
Reaction mass of (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide and tertbutyl methyl ether
955-078-7 - Active Intermediate Joint Intermediate use only 28-06-2022 View substance registered dossier
Reaction mass of (1R,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane and (1S,4R,6R)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane
944-171-8 - Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
Reaction mass of (1R,4S,4aR,8R,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8S,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1R,4S,4aR,8S,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8R,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one
700-770-4 - No longer Valid Intermediate Joint No longer valid 03-12-2020 View substance registered dossier
Reaction mass of (1R,5R)-5-isopropyl-2-methylenecyclohexanol and (1S,5R)-5-isopropyl-2-methylenecyclohexanol
944-198-5 339267-31-1 Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
Reaction mass of (1RS,14SR)-14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene and (1RS,14RS)-14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene
948-273-3 73125-89-0 Active Intermediate Joint Intermediate use only 30-04-2021 View substance registered dossier
Reaction mass of (1S,2E,4S,4aS,8aS)-2-ethylidene-7-methyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene and (1S,2E,4S,4aS,8aS)-2-ethylidene-6-methyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene
807-817-9 52690-72-9 Active Intermediate Joint Intermediate use only 25-09-2017 View substance registered dossier
Reaction Mass of (1S,3R,6R)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane and (1R,3R,6S)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane
944-172-3 - Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
Reaction mass of (1S,6R)-3,7,7-trimethylbicyclo[4.1.0]hept-2-ene and (1R,6S)-3,7,7-trimethylbicyclo[4.1.0]hept-2-ene
701-285-0 554-61-0 Active Intermediate Joint Intermediate use only 07-06-2019 View substance registered dossier
Reaction mass of (1Z)-prop-1-en-1-ylphosphonic acid and prop-2-en-1-ylphosphonic acid
944-204-6 - Active Intermediate Joint Intermediate use only 31-01-2018 View substance registered dossier
Reaction mass of (1α,2β,5α)-2,6,6-trimethylbicyclo[3.1.1]heptane and pinanyl hydroperoxide
911-929-4 - Cease Manufacture Intermediate Joint Cease manufacture 12-06-2020 View substance registered dossier
Reaction mass of (2E) 1-Bromo-6,6-dimethyl-2-hepten-4-yne and (2Z)- 1-Bromo-6,6-dimethyl-2-hepten-4-yne
900-137-4 - Active Intermediate Joint Intermediate use only 29-05-2017 View substance registered dossier
Reaction mass of (2E,4Z,6E,8E)-ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate and (2E,4E,6E,8E)-ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
941-877-8 - Active Intermediate Joint Intermediate use only 02-03-2015 View substance registered dossier
Reaction mass of (2R,7aR)-2,4,6,6-Tetramethyl-7,7a-dihydro-1,3-benzodioxol-5(6H)-one and (2S,7aS)-2,4,6,6-Tetramethyl-7,7a-dihydro-1,3-benzodioxol-5(6H)-one
942-324-3 - Active Intermediate Joint Intermediate use only 26-05-2015 View substance registered dossier
Reaction mass of (2RS,3RS,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol and (2S,3S,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol
948-387-3 171598-74-6 Active Intermediate Joint Intermediate use only 30-10-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active R,R-2-carboxy –[2-(2-propen-1-yl)-cyclopropyl] benzoate dicyclohexylamonium salt 944-401-7 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active R-(+)-1-(1-naphthyl)ethylamine 223-425-5 3886-70-2 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Raloxifene 686-786-1 84449-90-1 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active Ranitidine 266-332-5 66357-35-5 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Ranitidine 266-332-5 66357-35-5 2017 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Cease Manufacture Rapamycin 610-965-5 53123-88-9 2017 View substance registered dossier
Zschimmer & Schwarz GmbH & Co KG Max-Schwarz-Str. 3-5 56112 Lahnstein Germany Germany Active Rape oil, oxidized 305-871-3 95193-59-2 2012 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active reaction and salt formation product of benzene-1,2-dicarboxylic acid and chlorine 923-003-7 - - View substance registered dossier
SBS 30 rue Gambetta BP 206 40105 DAX France France Active Reaction mass 2-methylpenta-1,3-diene and 4-methylpenta-1,3-diene and 4-methylpent-4-en-2-ol 937-376-9 - 2012 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active Reaction mass E-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide and Z-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide 936-979-4 - 2013; 2022 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Reaction mass E-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide and Z-2-[4-(2-chloro-1,-diphenylethenyl)phenoxy]-N,N-diethylethanamine, hydrobromide 936-979-4 - 2012 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Reaction mass of (+/-)-(S*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran and (1’S, 2R)-2-(1’, 2’-Dihydroxyethyl)-6-fluorochromane 948-018-6 - 2018 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Reaction mass of (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide and tertbutyl methyl ether 955-078-7 - - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Reaction mass of (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide and tertbutyl methyl ether 955-078-7 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active Reaction mass of (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide and tertbutyl methyl ether 955-078-7 - - View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active Reaction mass of (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide and tertbutyl methyl ether 955-078-7 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of (1R,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane and (1S,4R,6R)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane 944-171-8 - - View substance registered dossier
[Confidential] - - - Reaction mass of (1R,4S,4aR,8R,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8S,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1R,4S,4aR,8S,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8R,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one 700-770-4 - - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid Reaction mass of (1R,4S,4aR,8R,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8S,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1R,4S,4aR,8S,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8R,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one 700-770-4 - 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of (1R,5R)-5-isopropyl-2-methylenecyclohexanol and (1S,5R)-5-isopropyl-2-methylenecyclohexanol 944-198-5 339267-31-1 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active Reaction mass of (1RS,14SR)-14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene and (1RS,14RS)-14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene 948-273-3 73125-89-0 - View substance registered dossier
[Confidential] - - - Reaction mass of (1S,2E,4S,4aS,8aS)-2-ethylidene-7-methyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene and (1S,2E,4S,4aS,8aS)-2-ethylidene-6-methyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene 807-817-9 52690-72-9 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction Mass of (1S,3R,6R)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane and (1R,3R,6S)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane 944-172-3 - - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active Reaction mass of (1S,6R)-3,7,7-trimethylbicyclo[4.1.0]hept-2-ene and (1R,6S)-3,7,7-trimethylbicyclo[4.1.0]hept-2-ene 701-285-0 554-61-0 2018; 2019 View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active Reaction mass of (1Z)-prop-1-en-1-ylphosphonic acid and prop-2-en-1-ylphosphonic acid 944-204-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Cease Manufacture Reaction mass of (1α,2β,5α)-2,6,6-trimethylbicyclo[3.1.1]heptane and pinanyl hydroperoxide 911-929-4 - 2020 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Reaction mass of (2E) 1-Bromo-6,6-dimethyl-2-hepten-4-yne and (2Z)- 1-Bromo-6,6-dimethyl-2-hepten-4-yne 900-137-4 - - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Reaction mass of (2E,4Z,6E,8E)-ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate and (2E,4E,6E,8E)-ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate 941-877-8 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Reaction mass of (2R,7aR)-2,4,6,6-Tetramethyl-7,7a-dihydro-1,3-benzodioxol-5(6H)-one and (2S,7aS)-2,4,6,6-Tetramethyl-7,7a-dihydro-1,3-benzodioxol-5(6H)-one 942-324-3 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Reaction mass of (2RS,3RS,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol and (2S,3S,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol 948-387-3 171598-74-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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