Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
tert-butyl 4-cyanopiperidine-1-carboxylate
624-826-1 91419-52-2 Active Intermediate Joint Intermediate use only 15-07-2021 View substance registered dossier
tert-Butyl 4-{[(methylsulfonyl)oxy]methyl}tetrahydro-1(2H)-pyridinecarboxylate
800-659-1 161975-39-9 Active Intermediate Joint Intermediate use only 12-05-2022 View substance registered dossier
tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate
836-116-0 480452-36-6 Active Intermediate Joint Intermediate use only 07-06-2022 View substance registered dossier
tert-butyl acetate
208-760-7 540-88-5 Active Intermediate Individual Intermediate use only 14-09-2020 View substance registered dossier
tert-butyl bromoacetate
226-133-6 5292-43-3 Active Intermediate Joint Intermediate use only 22-01-2019 View substance registered dossier
tert-butyl carbazate
212-795-3 870-46-2 Active Intermediate Joint Intermediate use only 21-02-2019 View substance registered dossier
tert-butyl chloroacetate
203-506-1 107-59-5 Active Intermediate Joint Intermediate use only 23-07-2018 View substance registered dossier
tert-butyl hypochlorite
208-072-7 507-40-4 Active Intermediate Joint Intermediate use only 14-01-2019 View substance registered dossier
tert-butyl isocyanate
216-544-9 1609-86-5 Active Intermediate Joint Intermediate use only 03-12-2015 View substance registered dossier
tert-butyl N-(4-chloro-2-formylphenyl)carbamate
839-772-6 260559-52-2 Active Intermediate Individual Intermediate use only 12-06-2019 View substance registered dossier
tert-butyl N-(4-chlorophenyl)carbamate
674-120-2 18437-66-6 Active Intermediate Individual Intermediate use only 29-11-2018 View substance registered dossier
tert-butyl N-[(E)-(4-pyridin-2-ylphenyl)methylideneamino]carbamate
918-454-1 - Active Intermediate Joint Intermediate use only 08-03-2018 View substance registered dossier
tert-butyl nitrite
208-757-0 540-80-7 Active Intermediate Individual Intermediate use only 27-09-2019 View substance registered dossier
tert-butyl piperazine-1-carboxylate
611-489-0 57260-71-6 Active Intermediate Joint Intermediate use only 27-09-2018 View substance registered dossier
tert-butyl piperazine-1-carboxylate
611-489-0 57260-71-6 Active Intermediate Individual Intermediate use only 18-09-2015 View substance registered dossier
tert-butyl piperazine-1-carboxylate
611-489-0 57260-71-6 Active Intermediate Individual Intermediate use only 30-04-2013 View substance registered dossier
Tert-butyl tert-butyldimethylsilyl [(2S)-2-(benzyloxy)propylidene]carbonohydrazonate
925-662-6 - Active Intermediate Individual Intermediate use only 22-10-2018 View substance registered dossier
tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate
431-870-3 - Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate
432-810-9 1379976-09-6 Active Intermediate Joint Intermediate use only 24-10-2012 View substance registered dossier
tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate
432-810-9 1379976-09-6 Active Intermediate Joint Intermediate use only 02-12-2020 View substance registered dossier
tert-Butyl(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}-cyclohexyl)carbamate
820-404-8 506427-91-4 Active Intermediate Individual Intermediate use only 06-07-2021 View substance registered dossier
Tert-butyl-2-methyl-2-(methylsulfonyloxy) propanoate
815-960-3 1350817-83-2 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
Tert-butyl-[1-(diphenylmethyl)azetidin-3-yl]carbamat
871-601-0 91189-18-3 Active Intermediate Individual Intermediate use only 09-11-2021 View substance registered dossier
tert-butyl-dimethyl-piperazin-1-ylsilane
815-305-1 138938-64-4 Active Intermediate Joint Intermediate use only 08-11-2017 View substance registered dossier
tert-butylbenzene
202-632-4 98-06-6 Active Intermediate Joint Intermediate use only 03-01-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-cyanopiperidine-1-carboxylate 624-826-1 91419-52-2 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-Butyl 4-{[(methylsulfonyl)oxy]methyl}tetrahydro-1(2H)-pyridinecarboxylate 800-659-1 161975-39-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate 836-116-0 480452-36-6 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate 836-116-0 480452-36-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl acetate 208-760-7 540-88-5 - View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
Eumedica Pharmaceuticals Industries, S.L. Peña Brava Parc. 22 B-23 33192 Llanera Asturias Spain Spain Active tert-butyl hypochlorite 208-072-7 507-40-4 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active tert-butyl isocyanate 216-544-9 1609-86-5 2014 View substance registered dossier
KISCHEMICALS LLC Gyártelep 3792 Sajóbábony Hungary Hungary Active tert-butyl isocyanate 216-544-9 1609-86-5 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl N-(4-chloro-2-formylphenyl)carbamate 839-772-6 260559-52-2 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl N-(4-chlorophenyl)carbamate 674-120-2 18437-66-6 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active tert-butyl N-[(E)-(4-pyridin-2-ylphenyl)methylideneamino]carbamate 918-454-1 - - View substance registered dossier
Chemservice S.A. (V3S9) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active tert-butyl nitrite 208-757-0 540-80-7 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
Chemsafe Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
[Confidential] - - - tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active tert-butyl piperazine-1-carboxylate 611-489-0 57260-71-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active Tert-butyl tert-butyldimethylsilyl [(2S)-2-(benzyloxy)propylidene]carbonohydrazonate 925-662-6 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate 432-810-9 1379976-09-6 - View substance registered dossier
Avara Avlon Pharma Services Ltd Avlon Works Severn Road, Hallen BS10 7ZE Bristol United Kingdom United Kingdom No longer Valid tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate 432-810-9 1379976-09-6 2021 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate 432-810-9 1379976-09-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}(4S,6S)-2,2-dimethyl[1,3]dioxan-4-yl)acetate 432-810-9 1379976-09-6 2010; 2012; 2018; 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active tert-Butyl(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}-cyclohexyl)carbamate 820-404-8 506427-91-4 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active Tert-butyl-2-methyl-2-(methylsulfonyloxy) propanoate 815-960-3 1350817-83-2 2021 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active Tert-butyl-[1-(diphenylmethyl)azetidin-3-yl]carbamat 871-601-0 91189-18-3 - View substance registered dossier
Shin-Etsu Silicones Europe BV Bolderweg 32 1332 AV Almere Netherlands Netherlands Active tert-butyl-dimethyl-piperazin-1-ylsilane 815-305-1 138938-64-4 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany Germany Active tert-butylbenzene 202-632-4 98-06-6 2019 View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active tert-butylbenzene 202-632-4 98-06-6 - View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active tert-butylbenzene 202-632-4 98-06-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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