Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]-amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquimolinecarboxylic acid monohydrochloride, acetone solvate
919-408-3 - Active Intermediate Individual Intermediate use only 14-01-2020 View substance registered dossier
2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one
P-964
420-580-2 151798-26-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[3-(methylamino)propyl]-1H-benzimidazole
425-760-4 64137-52-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl] ethanol
700-085-0 329216-67-3 Active Intermediate Individual Intermediate use only 04-11-2010 View substance registered dossier
2-[4-[N-ethyl-4-(2-methoxyethoxy)anilino]phenyl]ethene-1,1,2-tricarbonitrile
434-930-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethylamine dihydrochloride
254-033-2 38603-72-4 Active Intermediate Individual Intermediate use only 03-03-2015 View substance registered dossier
2-[[2-(2-hydroxyethoxy)-4-nitrophenyl]amino]ethanol
HC YELLOW NO. 4
428-840-7 59820-43-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[[2-(acetyloxy)-3-(1,1-dimethylethyl)-5-methylphenyl]methyl]-6-(1,1-dimethylethyl)-4-methylphenol
ST112HBI
412-210-3 41620-33-1 Cease Manufacture NONS Individual Cease manufacture 07-06-2012 View substance registered dossier
2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2-carboxylphenyl)-3-oxo-butanamide;2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2-methylphenyl)-3-oxo-butanamide;reaction mass of: 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)]-3-oxo-butanamide
434-330-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[[4-(4-aminophenyl)diazenyl-3-methyl-phenyl]-(2-hydroxyethyl)amino]ethanol
416-420-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[benzyl(methyl)amino]-1-(3,4-dihydroxyphenyl)ethanone
814-489-0 36467-25-1 Active Intermediate Individual Intermediate use only 16-12-2019 View substance registered dossier
2-[hydroxy-(4-phenoxyphenyl)methylene]propanedinitrile
858-256-1 330792-68-2 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
2-[methoxy-(4-phenoxyphenyl)methylene]propanedinitrile
858-257-7 330792-69-3 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
2-Acetone, polymer with phenol
500-086-4 35238-34-7 Active Full Individual ≥ 1 000 to < 10 000 tonnes 16-10-2019 View substance registered dossier
2-acetoxyethyl stearate
245-122-7 22613-51-0 Active Full Individual ≥ 0 to < 10 tonnes 22-05-2018 View substance registered dossier
2-acetoxymethyl-4-bromo-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)tetrahydrofuran-3-yl acetate
2'-BROMO-2'-DEOXY-3',5'-DIACETYL-5-METHYLURIDINE
443-810-3 110483-43-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl
ATRAC 869
417-960-5 - Active NONS Individual Tonnage data confidential 01-08-2013 View substance registered dossier
2-Amino-3-bromopyridine
629-620-5 13534-99-1 Active Intermediate Individual Intermediate use only 18-09-2018 View substance registered dossier
2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester
829-017-9 1034975-35-3 Active Intermediate Individual Intermediate use only 30-05-2019 View substance registered dossier
2-amino-4-bromo-5-chlorobenzoic acid
ACIDE CÉBRANILIQUE
424-700-4 150812-32-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine
415-500-8 145963-84-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester
480-220-5 393509-78-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone
814-705-3 6940-45-0 Active Full Individual ≥ 0 to < 10 tonnes 27-05-2018 View substance registered dossier
2-Amino-5-Chloro-N,3-Dimethylbenzamide
618-233-7 890707-28-5 Active Full Individual ≥ 1 to < 10 tonnes 15-06-2020 View substance registered dossier
2-amino-5-chlorobenzothiazole
451-710-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - 2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]-amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquimolinecarboxylic acid monohydrochloride, acetone solvate 919-408-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one 420-580-2 151798-26-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 2-[3-(methylamino)propyl]-1H-benzimidazole 425-760-4 64137-52-6 - View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl] ethanol 700-085-0 329216-67-3 2009; 2010 View substance registered dossier
- - - - 2-[4-[N-ethyl-4-(2-methoxyethoxy)anilino]phenyl]ethene-1,1,2-tricarbonitrile 434-930-7 - - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethylamine dihydrochloride 254-033-2 38603-72-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-[[2-(2-hydroxyethoxy)-4-nitrophenyl]amino]ethanol 428-840-7 59820-43-8 - View substance registered dossier
Kodak Alaris Germany GmbH Augsburger Str. 712 70329 Stuttgart Germany Germany Cease Manufacture 2-[[2-(acetyloxy)-3-(1,1-dimethylethyl)-5-methylphenyl]methyl]-6-(1,1-dimethylethyl)-4-methylphenol 412-210-3 41620-33-1 2019 View substance registered dossier
Sun Chemical A/S 8 Københavnsvej 112 DK-4600 Køge Denmark Denmark Active 2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2-carboxylphenyl)-3-oxo-butanamide;2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2-methylphenyl)-3-oxo-butanamide;reaction mass of: 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)]-3-oxo-butanamide 434-330-5 - - View substance registered dossier
- - - - 2-[[4-(4-aminophenyl)diazenyl-3-methyl-phenyl]-(2-hydroxyethyl)amino]ethanol 416-420-6 - - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2-[benzyl(methyl)amino]-1-(3,4-dihydroxyphenyl)ethanone 814-489-0 36467-25-1 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-[hydroxy-(4-phenoxyphenyl)methylene]propanedinitrile 858-256-1 330792-68-2 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-[methoxy-(4-phenoxyphenyl)methylene]propanedinitrile 858-257-7 330792-69-3 - View substance registered dossier
Hexion B.V. Seattleweg 17, building 4 3195 ND Pernis-Rotterdam Netherlands Netherlands Active 2-Acetone, polymer with phenol 500-086-4 35238-34-7 2010; 2014; 2019 View substance registered dossier
Vevy Europe SpA Via Semeria 16a 16131 Genova Italy Italy Active 2-acetoxyethyl stearate 245-122-7 22613-51-0 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-acetoxymethyl-4-bromo-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)tetrahydrofuran-3-yl acetate 443-810-3 110483-43-7 - View substance registered dossier
[Confidential] - - - 2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl 417-960-5 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 2-Amino-3-bromopyridine 629-620-5 13534-99-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester 829-017-9 1034975-35-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2-amino-4-bromo-5-chlorobenzoic acid 424-700-4 150812-32-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine 415-500-8 145963-84-4 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester 480-220-5 393509-78-9 - View substance registered dossier
SupraPolix BV Horsten 1 5612 AX Eindhoven Netherlands Netherlands Active 2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone 814-705-3 6940-45-0 - View substance registered dossier
ADAMA Agriculture BV Arnhemseweg 87 Postbus 355 3830 AK Leusden Netherlands Netherlands Active 2-Amino-5-Chloro-N,3-Dimethylbenzamide 618-233-7 890707-28-5 - View substance registered dossier
- - - - 2-amino-5-chlorobenzothiazole 451-710-6 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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