Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
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  • Consumer Uses
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  • Uses at industrial sites
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Details
2-[[4-(4-aminophenyl)diazenyl-3-methyl-phenyl]-(2-hydroxyethyl)amino]ethanol
416-420-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
440-920-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-[benzyl(2-hydroxyethyl)amino]-1-phenylethanol
607-206-5 23175-18-0 Active Intermediate Individual Intermediate use only 30-11-2012 View substance registered dossier
2-[benzyl(methyl)amino]-1-(3,4-dihydroxyphenyl)ethanone
814-489-0 36467-25-1 Active Intermediate Individual Intermediate use only 16-12-2019 View substance registered dossier
2-[difluoro(methoxy)methyl]-1,1,1,3,3,3-hexafluoropropane
609-534-4 382-26-3 Active Intermediate Individual Intermediate use only 19-03-2019 View substance registered dossier
2-[hydroxy-(4-phenoxyphenyl)methylene]propanedinitrile
858-256-1 330792-68-2 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
2-[methoxy-(4-phenoxyphenyl)methylene]propanedinitrile
858-257-7 330792-69-3 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
2-[{6-[(4-amino-6-chloro-1,3,5-triazin-2-yl)(methyl)amino]-1-hydroxy-3-sulfonaphthalen-2-yl}diazenyl]naphthalene-1,5-disulfonic acid, lithium sodium salts
942-710-1 - Active Full Individual ≥ 10 to < 100 tonnes 23-01-2020 View substance registered dossier
2-acetamido-5-chlorobenzenesulfonic acid - pyridine (1:1)
805-128-8 54981-42-9 Active Intermediate Individual Intermediate use only 05-03-2014 View substance registered dossier
2-Acetone, polymer with phenol
500-086-4 35238-34-7 Active Full Individual ≥ 1 000 to < 10 000 tonnes 16-10-2019 View substance registered dossier
2-acetoxyethyl stearate
245-122-7 22613-51-0 Active Full Individual ≥ 0 to < 10 tonnes 22-05-2018 View substance registered dossier
2-acetoxymethyl-4-bromo-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)tetrahydrofuran-3-yl acetate
443-810-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl
417-960-5 - Active NONS Individual Tonnage data confidential 01-08-2013 View substance registered dossier
2-Amino-3-bromopyridine
629-620-5 13534-99-1 Active Intermediate Individual Intermediate use only 18-09-2018 View substance registered dossier
2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylene]propanehydrazide hydrochloride (1:1)
940-411-0 1353749-74-2 Active Intermediate Individual Intermediate use only 03-05-2018 View substance registered dossier
2-Amino-4,5-dimethyl-thiophene-3-carbonitrile
610-309-8 4651-94-9 Active Intermediate Individual Intermediate use only 02-10-2012 View substance registered dossier
2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester
829-017-9 1034975-35-3 Active Intermediate Individual Intermediate use only 30-05-2019 View substance registered dossier
2-amino-4-bromo-5-chlorobenzoic acid
424-700-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine
415-500-8 145963-84-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester
480-220-5 393509-78-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone
814-705-3 6940-45-0 Active Full Individual ≥ 0 to < 10 tonnes 27-05-2018 View substance registered dossier
2-amino-5-bromopyridin-3-yl 4-methylbenzenesulfonate
943-013-5 - Active Intermediate Individual Intermediate use only 04-01-2016 View substance registered dossier
2-Amino-5-Chloro-N,3-Dimethylbenzamide
618-233-7 890707-28-5 Active Full Individual ≥ 1 to < 10 tonnes 15-06-2020 View substance registered dossier
2-amino-5-chlorobenzothiazole
451-710-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-5-methylthiazole
423-800-5 7305-71-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - 2-[[4-(4-aminophenyl)diazenyl-3-methyl-phenyl]-(2-hydroxyethyl)amino]ethanol 416-420-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 2-[[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane 440-920-3 - - View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active 2-[benzyl(2-hydroxyethyl)amino]-1-phenylethanol 607-206-5 23175-18-0 2012 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2-[benzyl(methyl)amino]-1-(3,4-dihydroxyphenyl)ethanone 814-489-0 36467-25-1 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 2-[difluoro(methoxy)methyl]-1,1,1,3,3,3-hexafluoropropane 609-534-4 382-26-3 2016; 2019 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-[hydroxy-(4-phenoxyphenyl)methylene]propanedinitrile 858-256-1 330792-68-2 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-[methoxy-(4-phenoxyphenyl)methylene]propanedinitrile 858-257-7 330792-69-3 - View substance registered dossier
Everlight Europe B.V. Rivium Boulevard 224 2909LK Capelle a/d Ijssel Netherlands Netherlands Active 2-[{6-[(4-amino-6-chloro-1,3,5-triazin-2-yl)(methyl)amino]-1-hydroxy-3-sulfonaphthalen-2-yl}diazenyl]naphthalene-1,5-disulfonic acid, lithium sodium salts 942-710-1 - 2017; 2020 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active 2-acetamido-5-chlorobenzenesulfonic acid - pyridine (1:1) 805-128-8 54981-42-9 - View substance registered dossier
Hexion B.V. Seattleweg 17, building 4 3195 ND Pernis-Rotterdam Netherlands Netherlands Active 2-Acetone, polymer with phenol 500-086-4 35238-34-7 2010; 2014; 2019 View substance registered dossier
Vevy Europe SpA Via Semeria 16a 16131 Genova Italy Italy Active 2-acetoxyethyl stearate 245-122-7 22613-51-0 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-acetoxymethyl-4-bromo-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)tetrahydrofuran-3-yl acetate 443-810-3 - - View substance registered dossier
[Confidential] - - - 2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl 417-960-5 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 2-Amino-3-bromopyridine 629-620-5 13534-99-1 - View substance registered dossier
SP QUIMICA SA Crta. Reus a Riudoms Km. 4, 1 43330 RIUDOMS TARRAGONA Spain Spain Active 2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylene]propanehydrazide hydrochloride (1:1) 940-411-0 1353749-74-2 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-Amino-4,5-dimethyl-thiophene-3-carbonitrile 610-309-8 4651-94-9 2012 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester 829-017-9 1034975-35-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2-amino-4-bromo-5-chlorobenzoic acid 424-700-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine 415-500-8 145963-84-4 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester 480-220-5 393509-78-9 - View substance registered dossier
SupraPolix BV Horsten 1 5612 AX Eindhoven Netherlands Netherlands Active 2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone 814-705-3 6940-45-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 2-amino-5-bromopyridin-3-yl 4-methylbenzenesulfonate 943-013-5 - - View substance registered dossier
ADAMA Agriculture BV Arnhemseweg 87 Postbus 355 3830 AK Leusden Netherlands Netherlands Active 2-Amino-5-Chloro-N,3-Dimethylbenzamide 618-233-7 890707-28-5 - View substance registered dossier
- - - - 2-amino-5-chlorobenzothiazole 451-710-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-amino-5-methylthiazole 423-800-5 7305-71-7 - View substance registered dossier

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