Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, (2S,3S,5R)-
618-304-2 89789-07-1 Active Intermediate Joint Intermediate use only 13-03-2018 View substance registered dossier
4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)-
457-660-1 104797-47-9 Cease Manufacture Full Joint Cease manufacture 03-05-2018 View substance registered dossier
4-trans-(3-penten-1-yl)-4'-trans-propyl-1,1'-bicyclohexyl
806-827-0 105351-42-6 Active Full Joint ≥ 0 to < 10 tonnes 03-04-2018 View substance registered dossier
4-trans-(4-trans-Propylcyclohexyl)-cyclohexancarbonic acid
613-782-9 65355-32-0 Active Full Joint ≥ 0 to < 10 tonnes 07-10-2020 View substance registered dossier
4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd
604-491-8 145767-92-6 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-trans-Butyl-4'-trans-propyl-[1,1'-bicyclohexyl]
619-232-4 96624-52-1 Active Full Joint ≥ 0 to < 10 tonnes 10-01-2019 View substance registered dossier
4-trans-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl]
619-230-3 96624-41-8 Active Full Joint ≥ 0 to < 10 tonnes 08-01-2019 View substance registered dossier
4-trans-Methoxy-4-trans-propyl-[1,1-bicyclohexyl]
619-269-6 97398-80-6 Active Full Joint ≥ 0 to < 10 tonnes 25-03-2020 View substance registered dossier
4-trans-Pentyl-4'-trans-propyl-[1,1'-bicyclohexyl]
618-832-3 92263-41-7 Active Full Joint ≥ 0 to < 10 tonnes 19-02-2019 View substance registered dossier
4-trans-propenylveratrole
228-958-7 6379-72-2 Active Full Joint ≥ 10 to < 100 tonnes 31-03-2022 View substance registered dossier
4-trans-Propyl-4-trans-(3,4,5-trifluorphenyl)-[1,1-bicyclohexyl]
603-522-2 131819-23-3 Active Full Joint ≥ 1 to < 10 tonnes 15-01-2018 View substance registered dossier
4-vinylcyclohexene
202-848-9 100-40-3 Active Intermediate Joint Intermediate use only 11-07-2017 View substance registered dossier
4-vinylpyridine
202-852-0 100-43-6 Active Full Joint ≥ 100 to < 1 000 tonnes 24-04-2013 View substance registered dossier
4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid
926-027-6 - Active Intermediate Joint Intermediate use only 08-07-2019 View substance registered dossier
4H-1,2,4-triazol-4-ylamine
209-533-5 584-13-4 Active Full Joint ≥ 0 to < 10 tonnes 16-12-2021 View substance registered dossier
4H-1,3-Dioxino[4,5-c]pyridine-5-carboxaldehyde, 2,2,8-trimethyl-
922-317-1 6560-65-2 Active Intermediate Joint Intermediate use only 24-03-2017 View substance registered dossier
4H-1,3-Dioxino[4,5-c]pyridine-5-methanol, .alpha.-(4-chlorophenyl)-2,2,8-trimethyl-
814-124-5 133545-64-9 Active Intermediate Joint Intermediate use only 10-05-2017 View substance registered dossier
4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester
605-256-2 16150-45-1 Active Intermediate Joint Intermediate use only 04-04-2018 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 25-01-2018 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 09-07-2021 View substance registered dossier
4H-Indeno[4,5-d]-1,3-dioxole, 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl-
457-070-4 823178-41-2 Active NONS Joint Tonnage data confidential 09-09-2019 View substance registered dossier
4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro-
917-666-1 61196-37-0 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-acetyl-1,2,3,6,7,11b-hexahydro-
470-180-7 61196-40-5 Active Intermediate Joint Intermediate use only 18-10-2019 View substance registered dossier
4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-9-hydroxy-2-methyl-, hydrochloride (1:1)
617-648-0 849727-62-4 Active Full Joint ≥ 0 to < 10 tonnes 27-03-2017 View substance registered dossier
4H-Pyrido[1,2-a]pyrimidin-4-one, 9-hydroxy-3-(2-hydroxyethyl)-2-methyl-
605-935-3 181525-38-2 Active Full Joint ≥ 1 to < 10 tonnes 23-08-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, (2S,3S,5R)- 618-304-2 89789-07-1 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)- 457-660-1 104797-47-9 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-(3-penten-1-yl)-4'-trans-propyl-1,1'-bicyclohexyl 806-827-0 105351-42-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-(4-trans-Propylcyclohexyl)-cyclohexancarbonic acid 613-782-9 65355-32-0 2018; 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd 604-491-8 145767-92-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-Butyl-4'-trans-propyl-[1,1'-bicyclohexyl] 619-232-4 96624-52-1 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl] 619-230-3 96624-41-8 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-Methoxy-4-trans-propyl-[1,1-bicyclohexyl] 619-269-6 97398-80-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-Pentyl-4'-trans-propyl-[1,1'-bicyclohexyl] 618-832-3 92263-41-7 2019 View substance registered dossier
FIRMENICH GRASSE SAS OR 0 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
REACHLaw Ltd( acting as OR for Yasho Industries Limited) Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland Finland Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 4-trans-propenylveratrole 228-958-7 6379-72-2 2022 View substance registered dossier
Luxcontrol S.A. (OR64) 1, Avenue des Terres Rouges 4331 Esch-sur-Alzette Luxembourg Luxembourg Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
Société grassoise de Parfumerie 12, BD Pasteur 06130 Grasse France France Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active 4-trans-propenylveratrole 228-958-7 6379-72-2 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-Propyl-4-trans-(3,4,5-trifluorphenyl)-[1,1-bicyclohexyl] 603-522-2 131819-23-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4-vinylcyclohexene 202-848-9 100-40-3 2016; 2017 View substance registered dossier
Vertellus Specialties Belgium NV Havenlaan 86-C- bus 204 1000 Brussels Belgium Belgium Active 4-vinylpyridine 202-852-0 100-43-6 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid 926-027-6 - - View substance registered dossier
DUSLO Administrativna budova ev.č 1236 927 03 Šaľa Slovakia Slovakia Active 4H-1,2,4-triazol-4-ylamine 209-533-5 584-13-4 2021 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4H-1,3-Dioxino[4,5-c]pyridine-5-carboxaldehyde, 2,2,8-trimethyl- 922-317-1 6560-65-2 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4H-1,3-Dioxino[4,5-c]pyridine-5-methanol, .alpha.-(4-chlorophenyl)-2,2,8-trimethyl- 814-124-5 133545-64-9 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 2016 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 2010; 2013; 2016 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
LUMINOCHEM Kutató-Fejlesztő Kft. Háros utca 7/a 1222 Budapest Hungary Hungary Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 4H-Indeno[4,5-d]-1,3-dioxole, 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl- 457-070-4 823178-41-2 2012; 2019 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro- 917-666-1 61196-37-0 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-acetyl-1,2,3,6,7,11b-hexahydro- 470-180-7 61196-40-5 2013; 2019 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-9-hydroxy-2-methyl-, hydrochloride (1:1) 617-648-0 849727-62-4 2017 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-hydroxy-3-(2-hydroxyethyl)-2-methyl- 605-935-3 181525-38-2 2017 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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