Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
2-Propenoic acid, 2-methyl-, 2-(4-benzoyl-3-hydroxyphenoxy)ethyl ester
700-105-8 16613-04-0 Active Full Individual ≥ 1 to < 10 tonnes 27-02-2009 View substance registered dossier
2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester
424-240-4 96478-09-0 Active Full Individual ≥ 1 to < 10 tonnes 26-10-2012 View substance registered dossier
2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester
424-240-4 96478-09-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Propenoic acid, 2-methyl-, 2-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethyl-1-pentasiloxanyl)propoxy]ethyl ester
801-072-3 1052075-57-6 Active Full Individual ≥ 1 to < 10 tonnes 24-09-2014 View substance registered dossier
2-Propenoic acid, 2-methyl-, C6-12-alkyl esters
292-081-6 90530-40-8 Active Full Individual ≥ 1 to < 10 tonnes 28-05-2018 View substance registered dossier
2-Propenoic acid, 2-methyl-, monoester with 1,2-propanediol, reaction products with dipropylene glycol and 1,1'-methylenebis[isocyanatobenzene]
923-201-3 1192143-92-2 Active Full Individual ≥ 100 to < 1 000 tonnes 09-09-2016 View substance registered dossier
2-Propenoic acid, 3-amino-2-cyano-, ethyl ester
609-521-3 38109-77-2 Active Intermediate Individual Intermediate use only 14-05-2013 View substance registered dossier
2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (2Z)-
943-053-3 1333154-26-9 Active Intermediate Individual Intermediate use only 16-09-2016 View substance registered dossier
2-Propenoic acid, tris(1-methylethyl)silyl ester
457-670-6 157859-20-6 Active Full Individual ≥ 100 to < 1 000 tonnes 22-10-2012 View substance registered dossier
2-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole
440-240-7 1282554-35-1 Active Intermediate Individual Intermediate use only 25-10-2016 View substance registered dossier
2-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole
440-240-7 1282554-35-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
2-propylvaleric acid
202-777-3 99-66-1 Active Intermediate Individual Intermediate use only 03-10-2011 View substance registered dossier
2-Pyrazinecarboxylic acid, 5-methyl-, methyl ester
620-310-5 41110-33-2 Active Intermediate Individual Intermediate use only 07-06-2017 View substance registered dossier
2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl-
692-721-8 757251-39-1 Active Intermediate Individual Intermediate use only 02-12-2014 View substance registered dossier
2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-
608-211-5 284462-37-9 Active Full Individual ≥ 1 to < 10 tonnes 12-11-2021 View substance registered dossier
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)
692-722-3 835621-07-3 Cease Manufacture Intermediate Individual Cease manufacture 15-12-2014 View substance registered dossier
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-
608-209-4 284461-73-0 Active Full Individual ≥ 10 to < 100 tonnes 30-06-2015 View substance registered dossier
2-Pyridinecarboxamide, 4-chloro-N-methyl-, hydrochloride (1:1)
692-719-7 882167-77-3 Active Intermediate Individual Intermediate use only 07-06-2019 View substance registered dossier
2-Pyridinecarboxamide, 5-fluoro-
813-292-7 499796-71-3 Cease Manufacture Intermediate Individual Cease manufacture 19-04-2017 View substance registered dossier
2-Pyridinecarboxylic acid, 4-amino-3,6-dichloro-
604-721-7 150114-71-9 No longer Valid Full Individual No longer valid 14-07-2020 View substance registered dossier
2-Pyridinecarboxylic acid, 5-fluoro-, methyl ester
813-296-9 107504-07-4 Cease Manufacture Intermediate Individual Cease manufacture 20-10-2016 View substance registered dossier
2-Pyridinesulfonamide, 3-(2,2,2-trifluoroethoxy)-, sodium salt (1:1)
700-926-1 227605-94-9 Cease Manufacture Intermediate Individual Cease manufacture 17-04-2015 View substance registered dossier
2-Pyrimidinamine, 4-methyl-N-phenyl-6-(1-propyn-1-yl)-
432-140-7 110235-47-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Pyrrolidinone, 5-ethenyl-
616-206-4 7529-16-0 Active Intermediate Individual Intermediate use only 16-11-2012 View substance registered dossier
2-tert-butoxyethanol
456-140-1 - Active Intermediate Individual Intermediate use only 11-10-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 2-Propenoic acid, 2-methyl-, 2-(4-benzoyl-3-hydroxyphenoxy)ethyl ester 700-105-8 16613-04-0 2009 View substance registered dossier
Covance Clinical Development SA 104 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 - View substance registered dossier
Shin-Etsu Silicones Europe BV Bolderweg 32 1332 AV Almere Netherlands Netherlands Active 2-Propenoic acid, 2-methyl-, 2-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethyl-1-pentasiloxanyl)propoxy]ethyl ester 801-072-3 1052075-57-6 2014 View substance registered dossier
Evonik Oil Additives S.A.S. Port du Rhin BP 79 67630 Lauterbourg France France Active 2-Propenoic acid, 2-methyl-, C6-12-alkyl esters 292-081-6 90530-40-8 2018 View substance registered dossier
Hilti Industriegesellschaft für Befestigungstechnik GmbH Hiltistraße 6 86916 Kaufering Germany Germany Active 2-Propenoic acid, 2-methyl-, monoester with 1,2-propanediol, reaction products with dipropylene glycol and 1,1'-methylenebis[isocyanatobenzene] 923-201-3 1192143-92-2 2014; 2016 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active 2-Propenoic acid, 3-amino-2-cyano-, ethyl ester 609-521-3 38109-77-2 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (2Z)- 943-053-3 1333154-26-9 - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active 2-Propenoic acid, tris(1-methylethyl)silyl ester 457-670-6 157859-20-6 2010; 2012 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 2-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole 440-240-7 1282554-35-1 2010; 2016 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 2-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole 440-240-7 1282554-35-1 2015 View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active 2-propylvaleric acid 202-777-3 99-66-1 2011 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2-Pyrazinecarboxylic acid, 5-methyl-, methyl ester 620-310-5 41110-33-2 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl- 692-721-8 757251-39-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl- 608-211-5 284462-37-9 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1) 692-722-3 835621-07-3 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl- 608-209-4 284461-73-0 2015 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Pyridinecarboxamide, 4-chloro-N-methyl-, hydrochloride (1:1) 692-719-7 882167-77-3 2019 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture 2-Pyridinecarboxamide, 5-fluoro- 813-292-7 499796-71-3 2019 View substance registered dossier
Corteva Agriscience UK Limited CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom United Kingdom No longer Valid 2-Pyridinecarboxylic acid, 4-amino-3,6-dichloro- 604-721-7 150114-71-9 2021 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture 2-Pyridinecarboxylic acid, 5-fluoro-, methyl ester 813-296-9 107504-07-4 2019 View substance registered dossier
CABB Oy Kemirantie 1 FI-67701 Kokkola Finland Finland Cease Manufacture 2-Pyridinesulfonamide, 3-(2,2,2-trifluoroethoxy)-, sodium salt (1:1) 700-926-1 227605-94-9 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 2-Pyrimidinamine, 4-methyl-N-phenyl-6-(1-propyn-1-yl)- 432-140-7 110235-47-7 - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 2-Pyrrolidinone, 5-ethenyl- 616-206-4 7529-16-0 2009; 2010; 2012 View substance registered dossier
Nagase (Europa) GmbH Werdener Straße 4 40227 Düsseldorf Germany Germany Active 2-tert-butoxyethanol 456-140-1 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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