Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-
813-253-4 96576-92-0 Active Intermediate Individual Intermediate use only 30-11-2016 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
619-405-4 99199-60-7 Cease Manufacture Intermediate Individual Cease manufacture 27-05-2013 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
619-405-4 99199-60-7 Active Intermediate Individual Intermediate use only 22-07-2011 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2R)-
810-841-2 129101-37-7 Active Intermediate Individual Intermediate use only 08-03-2016 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2S)-
810-842-8 129101-36-6 Active Intermediate Individual Intermediate use only 08-03-2016 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)-
927-046-2 1180001-17-5 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)-
807-022-7 1224567-85-4 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)-
600-381-9 1030385-16-0 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)-
603-316-2 129050-27-7 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
2H-1-Benzopyran-2-one, 6-bromo-3,4-dihydro-4-phenyl-
923-250-0 156755-23-6 Cease Manufacture Intermediate Individual Cease manufacture 07-07-2011 View substance registered dossier
2H-1-Benzopyran-6-methanol, 3,4-dihydro-2-hydroxy-4-phenyl-
700-143-5 959624-24-9 Cease Manufacture Intermediate Individual Cease manufacture 30-06-2009 View substance registered dossier
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-(dihydrogen phosphate), sodium salt (1:?)
478-070-0 299158-63-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2H-3,1-Benzoxazine-6-sulfonamide, 7-chloro-1,4-dihydro-2,4-dioxo-
811-480-3 23380-53-2 Active Intermediate Individual Intermediate use only 07-01-2016 View substance registered dossier
2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy-
456-160-0 73942-87-7 Active Full Individual ≥ 1 to < 10 tonnes 08-05-2014 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active Intermediate Individual Intermediate use only 17-11-2014 View substance registered dossier
2H-Indol-2-one, 1,3-dihydro-4-(2-hydroxyethyl)-
925-636-4 139122-19-3 Active Intermediate Individual Intermediate use only 08-03-2021 View substance registered dossier
2H-Indol-2-one, 1,3-dihydro-4-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-
917-449-1 139122-20-6 Active Intermediate Individual Intermediate use only 08-03-2021 View substance registered dossier
2H-Indol-2-one, 4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-
470-710-7 139122-17-1 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
2H-Isoindole-2-acetamide, N-[3-(2-chlorobenzoyl)-5-ethyl-2-thienyl]-1,3-dihydro-1,3-dioxo-
814-490-6 42753-80-0 Active Intermediate Individual Intermediate use only 15-05-2017 View substance registered dossier
2H-Pyran, 3-heptyltetrahydro-
462-530-2 854737-09-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2H-Pyran-4-carboxaldehyde, tetrahydro-
700-032-1 50675-18-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2008 View substance registered dossier
2H-Pyran-4-carboxylic acid, tetrahydro-, methyl ester
422-770-0 110238-91-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
809-888-1 1051375-16-6 Active Intermediate Individual Intermediate use only 21-06-2017 View substance registered dossier
2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl-
616-364-4 766-36-9 Active Intermediate Individual Intermediate use only 15-11-2013 View substance registered dossier
2P45AZ
428-820-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- 813-253-4 96576-92-0 - View substance registered dossier
Chemsafe S.r.l. Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Cease Manufacture 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro- 619-405-4 99199-60-7 2015 View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro- 619-405-4 99199-60-7 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2R)- 810-841-2 129101-37-7 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2S)- 810-842-8 129101-36-6 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)- 927-046-2 1180001-17-5 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)- 807-022-7 1224567-85-4 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)- 600-381-9 1030385-16-0 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)- 603-316-2 129050-27-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Cease Manufacture 2H-1-Benzopyran-2-one, 6-bromo-3,4-dihydro-4-phenyl- 923-250-0 156755-23-6 2015 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Cease Manufacture 2H-1-Benzopyran-6-methanol, 3,4-dihydro-2-hydroxy-4-phenyl- 700-143-5 959624-24-9 2015 View substance registered dossier
- - - - 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-(dihydrogen phosphate), sodium salt (1:?) 478-070-0 299158-63-7 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2H-3,1-Benzoxazine-6-sulfonamide, 7-chloro-1,4-dihydro-2,4-dioxo- 811-480-3 23380-53-2 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active 2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy- 456-160-0 73942-87-7 2014 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2H-Indol-2-one, 1,3-dihydro-4-(2-hydroxyethyl)- 925-636-4 139122-19-3 2021 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2H-Indol-2-one, 1,3-dihydro-4-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]- 917-449-1 139122-20-6 2021 View substance registered dossier
SmithKline Beecham plc 980 Great West Road TW8 9GS Brentford Middlesex United Kingdom United Kingdom No longer Valid 2H-Indol-2-one, 4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro- 470-710-7 139122-17-1 2021 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2H-Isoindole-2-acetamide, N-[3-(2-chlorobenzoyl)-5-ethyl-2-thienyl]-1,3-dihydro-1,3-dioxo- 814-490-6 42753-80-0 - View substance registered dossier
- - - - 2H-Pyran, 3-heptyltetrahydro- 462-530-2 854737-09-0 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture 2H-Pyran-4-carboxaldehyde, tetrahydro- 700-032-1 50675-18-8 2022 View substance registered dossier
- - - - 2H-Pyran-4-carboxylic acid, tetrahydro-, methyl ester 422-770-0 110238-91-0 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- 809-888-1 1051375-16-6 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl- 616-364-4 766-36-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2P45AZ 428-820-8 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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