Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Intermediate Individual Intermediate use only 11-06-2019 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Individual Intermediate use only 21-08-2013 View substance registered dossier
(R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8 25383-07-7 Active Full Individual ≥ 10 to < 100 tonnes 14-06-2016 View substance registered dossier
(R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8 25383-07-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol
278-718-0 77542-06-4 Active Intermediate Individual Intermediate use only 26-03-2019 View substance registered dossier
(R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate
445-750-3 839705-03-2 Active Intermediate Individual Intermediate use only 16-04-2013 View substance registered dossier
(R,S)-2-amino-3,3-dimethylbutane amide
447-860-7 144177-62-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-2-butyloctanedioic acid
2-BUTYLOCTANEDIOIC ACID
431-210-4 50905-10-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol
HEXACONAZOLE
413-050-7 79983-71-4 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(S)-(+)-1-methoxy-2-propylamine
700-220-3 99636-32-5 Active Intermediate Individual Intermediate use only 30-09-2010 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - No longer Valid Intermediate Individual No longer valid 22-09-2011 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-1,1-diphenyl-1,2-propanediol
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt
UK-81,786-57
425-510-4 167944-94-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide
824-341-7 357338-13-7 No longer Valid Full Individual No longer valid 02-10-2019 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 109425-51-6 Active Intermediate Individual Intermediate use only 09-03-2020 View substance registered dossier
(S)-2-amino-1,1-diphenyl 1-propanol
622-109-8 78603-91-5 Active Intermediate Individual Intermediate use only 30-11-2017 View substance registered dossier
(S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol
819-945-2 1006376-60-8 Active Intermediate Individual Intermediate use only 29-01-2018 View substance registered dossier
(S)-2-chloropropionic acid
L-2-CHLOROPROPIONIC ACID; L-2-CHLORPROPIONSÄURE
411-150-5 29617-66-1 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B
406-960-0 77497-97-3 Cease Manufacture Intermediate Individual Cease manufacture 04-10-2012 View substance registered dossier
(S)-3-hydroxy-γ-butyrolactone
434-990-4 7331-52-4 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid
430-900-2 192725-50-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol 278-718-0 77542-06-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate 445-750-3 839705-03-2 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (R,S)-2-amino-3,3-dimethylbutane amide 447-860-7 144177-62-8 - View substance registered dossier
Vishay BCcomponents B.V. Ceintuurbaan 15 8022 AW Zwolle Netherlands Netherlands Active (R,S)-2-butyloctanedioic acid 431-210-4 50905-10-7 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol 413-050-7 79983-71-4 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (S)-(+)-1-methoxy-2-propylamine 700-220-3 99636-32-5 2010 View substance registered dossier
Carbogen Amcis Ltd 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-1,1-diphenyl-1,2-propanediol 443-220-6 46755-94-6 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt 425-510-4 167944-94-7 - View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide 824-341-7 357338-13-7 2021 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 2019; 2020 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (S)-2-amino-1,1-diphenyl 1-propanol 622-109-8 78603-91-5 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol 819-945-2 1006376-60-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-2-chloropropionic acid 411-150-5 29617-66-1 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-3-hydroxy-γ-butyrolactone 434-990-4 7331-52-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid 430-900-2 192725-50-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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