Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(R)-(-)-3-Aminopiperidine dihydrochloride
608-870-9 334618-23-4 Active Intermediate Joint Intermediate use only 09-05-2018 View substance registered dossier
(R)-(-)-butane-1,3-diol
228-532-0 6290-03-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 17-04-2018 View substance registered dossier
(R)-(-)-butane-1,3-diol
228-532-0 6290-03-5 No longer Valid Intermediate Joint No longer valid 05-03-2020 View substance registered dossier
(R)-(3-carboxy-2-hydroxypropyl)trimethylammonium chloride
229-663-6 6645-46-1 Active Intermediate Joint Intermediate use only 28-09-2017 View substance registered dossier
(R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide
208-768-0 541-15-1 Active Full Joint ≥ 1 to < 10 tonnes 04-05-2020 View substance registered dossier
(R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide
208-768-0 541-15-1 Active Intermediate Joint Intermediate use only 24-01-2019 View substance registered dossier
(R)-(−)-3-Amino-1-Boc-piperidine
628-472-9 188111-79-7 Active Intermediate Joint Intermediate use only 12-01-2022 View substance registered dossier
(R)-1,1'-Binaphthalene-2,2'-diol
606-048-4 18531-94-7 Active Intermediate Joint Intermediate use only 11-11-2019 View substance registered dossier
(R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
R-THP
415-110-8 54417-53-7 Active Full Joint ≥ 1 to < 10 tonnes 15-09-2020 View substance registered dossier
(R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
R-THP
415-110-8 54417-53-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-1-(1-Naphthyl)ethylamine (R)-Mandelate
600-816-2 1073144-62-3 Active Intermediate Joint Intermediate use only 17-01-2018 View substance registered dossier
(R)-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2 51594-55-9 Cease Manufacture Intermediate Joint Cease manufacture 20-03-2018 View substance registered dossier
(R)-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2 51594-55-9 Active NONS Joint Tonnage data confidential 15-04-2011 View substance registered dossier
(R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride
444-320-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one
215-808-0 1415-73-2 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
(R)-12-hydroxy-N-(2-hydroxyethyl)oleamide
203-368-2 106-16-1 Active Intermediate Joint Intermediate use only 18-05-2016 View substance registered dossier
(R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde
224-815-8 4501-58-0 Active Intermediate Joint Intermediate use only 30-11-2021 View substance registered dossier
(R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate
845-262-4 1809816-36-1 Cease Manufacture Full Joint Cease manufacture 30-09-2020 View substance registered dossier
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-amino-3-phenylpropanol
226-086-1 5267-64-1 Active Intermediate Joint Intermediate use only 29-11-2018 View substance registered dossier
(R)-2-aminobutan-1-ol
227-476-4 5856-63-3 Active Intermediate Joint Intermediate use only 19-07-2019 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 Active Full Joint ≥ 10 to < 100 tonnes 16-12-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active (R)-(-)-3-Aminopiperidine dihydrochloride 608-870-9 334618-23-4 - View substance registered dossier
Mater-Biotech via Fauser 8 28100 Novara Italy Italy Active (R)-(-)-butane-1,3-diol 228-532-0 6290-03-5 2018 View substance registered dossier
TDeltaS Limited University of Oxford Department of Physiology, Anatomy & Genetics Sherrington Building, Parks Road OX1 3PT Oxford United Kingdom United Kingdom No longer Valid (R)-(-)-butane-1,3-diol 228-532-0 6290-03-5 2021 View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium chloride 229-663-6 6645-46-1 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide 208-768-0 541-15-1 2020 View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide 208-768-0 541-15-1 - View substance registered dossier
QUIMDIS SAS 71, rue Anatole France 92532 Levallois-Perret France France Active (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide 208-768-0 541-15-1 - View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide 208-768-0 541-15-1 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (R)-(−)-3-Amino-1-Boc-piperidine 628-472-9 188111-79-7 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active (R)-1,1'-Binaphthalene-2,2'-diol 606-048-4 18531-94-7 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride 415-110-8 54417-53-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride 415-110-8 54417-53-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride 415-110-8 54417-53-7 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-1-(1-Naphthyl)ethylamine (R)-Mandelate 600-816-2 1073144-62-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 2022 View substance registered dossier
Labcorp CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - 2019 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active (R)-10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one 215-808-0 1415-73-2 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (R)-12-hydroxy-N-(2-hydroxyethyl)oleamide 203-368-2 106-16-1 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2013 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate 845-262-4 1809816-36-1 2022 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 2019 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
International Flavors & Fragrances, I.F.F. (France) S.A.S Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 2018 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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