Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
2-hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine
428-200-7 103577-66-8 Active NONS Individual Tonnage data confidential 19-01-2011 View substance registered dossier
1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-
600-451-9 103577-40-8 Cease Manufacture Intermediate Individual Cease manufacture 04-10-2012 View substance registered dossier
1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-
600-451-9 103577-40-8 Active Intermediate Joint Intermediate use only 04-10-2017 View substance registered dossier
1-[4-(2-dimethylaminoethylsulfonyl)-phenyl-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazole
HOSTALUX VP 3481
401-410-6 10357-99-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Naftacencarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-methanoyl-1,11-dioxo-, (4S,4aS,5aR,12aS)
811-443-1 1035655-10-7 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
811-441-0 1035654-66-0 Active Intermediate Joint Intermediate use only 27-11-2019 View substance registered dossier
6,10-Dioxaspiro[4.5]decane-7-acetic acid, 9-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-, 1,1-dimethylethyl ester, (7R,9R)-
920-205-7 1035204-85-3 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
6,10-Dioxaspiro[4.5]decane-7-acetic acid, 9-(cyanomethyl)-, 1,1-dimethylethyl ester, (7R,9R)-
920-979-6 1035204-82-0 Active Intermediate Joint Intermediate use only 15-02-2013 View substance registered dossier
Androsta-4,9(11)-diene-3,17-dione
700-663-2 1035-69-4 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester
840-712-6 1034975-53-5 Active Intermediate Individual Intermediate use only 26-06-2019 View substance registered dossier
2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester
829-017-9 1034975-35-3 Active Intermediate Individual Intermediate use only 30-05-2019 View substance registered dossier
Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich
823-780-1 1034820-43-3 Active Full Joint ≥ 10 to < 100 tonnes 03-09-2021 View substance registered dossier
3-tert-butyladipic acid
233-759-3 10347-88-3 Active Full Joint ≥ 0 to < 10 tonnes 20-08-2018 View substance registered dossier
Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-, (9.beta.,11.beta.)-
600-439-3 103466-44-0 Active Intermediate Joint Intermediate use only 07-03-2018 View substance registered dossier
Graphene
801-282-5 1034343-98-0 Active Full Joint ≥ 10 to < 100 tonnes 08-03-2022 View substance registered dossier
(2-hydroxy-3-(3,4-dimethyl-9-oxo-10-thiaanthracen-2-yloxy)propyl)trimethylammonium chloride
QUANTACURE QTX
402-200-7 103430-24-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Dititanium tris(sulphate)
233-749-9 10343-61-0 Active Intermediate Joint Intermediate use only 29-03-2017 View substance registered dossier
3-Methoxy-3-methylbutyl acetate
700-408-5 103429-90-9 Active Full Individual ≥ 10 to < 100 tonnes 03-02-2020 View substance registered dossier
Ditetradecyl fumarate
233-739-4 10341-03-4 Active Full Joint ≥ 10 to < 100 tonnes 17-08-2015 View substance registered dossier
Titanium, [2,2-bis[(2-propenyloxy-.kappa.O)methyl]-1-butanolato-.kappa.O]tris(dodecylbenzenesulfonato-.kappa.O)-
418-130-5 103406-74-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
3,7-dimethylnona-1,6-dien-3-ol
233-732-6 10339-55-6 Active Full Joint ≥ 100 to < 1 000 tonnes 22-02-2021 View substance registered dossier
(2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid
813-635-0 103336-06-7 Active Intermediate Joint Intermediate use only 07-12-2018 View substance registered dossier
3-oxo-4-aza-5α-androstane-17β-carboxylic acid
5-ALPHA-AZA-ACID
407-820-1 103335-55-3 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
3-oxo-4-aza-5α-androstane-17β-carboxylic acid
5-ALPHA-AZA-ACID
407-820-1 103335-55-3 Active Intermediate Joint Intermediate use only 09-04-2019 View substance registered dossier
3-oxo-4-azaandrost-5-ene-17β-carboxylic acid
DELTA-5-AZA-ACID
407-830-6 103335-54-2 Active NONS Joint Tonnage data confidential 09-03-2021 View substance registered dossier
3-oxo-4-azaandrost-5-ene-17β-carboxylic acid
DELTA-5-AZA-ACID
407-830-6 103335-54-2 Active Intermediate Joint Intermediate use only 09-04-2019 View substance registered dossier
3-oxo-4-azaandrost-5-ene-17β-carboxylic acid
DELTA-5-AZA-ACID
407-830-6 103335-54-2 No longer Valid Full Individual No longer valid 12-04-2012 View substance registered dossier
Methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate
600-422-0 103335-41-7 Active Intermediate Joint Intermediate use only 08-04-2019 View substance registered dossier
1H-Benzimidazole, 2-[[(4-chloro-3-methyl-2-pyridinyl)methyl]thio]-
600-417-3 103312-62-5 Active Intermediate Individual Intermediate use only 14-03-2011 View substance registered dossier
L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl-
405-650-2 103300-91-0 Active Intermediate Individual Intermediate use only 02-11-2010 View substance registered dossier
L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl-
405-650-2 103300-91-0 Active NONS Joint Tonnage data confidential 17-02-2012 View substance registered dossier
L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl-
405-650-2 103300-91-0 Active Intermediate Individual Intermediate use only 10-02-2012 View substance registered dossier
L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl-
405-650-2 103300-91-0 Active Intermediate Individual Intermediate use only 21-11-2011 View substance registered dossier
N-(N6-trifluoroacetyl-L-lysyl)-L-proline
N-6-TRIFLUORACETYL-L-LYSYL-L-PROLIN; T.F.A. LYS PRO; TFA-LYS-PRO
402-920-1 103300-89-6 Active Full Joint ≥ 0 tonnes 24-03-2022 View substance registered dossier
2-(3,5-dichloro-2-hydroxyphenyl)quinazolin-4(3H)-one
600-418-9 1033-16-5 Active Full Joint ≥ 0 to < 10 tonnes 17-05-2018 View substance registered dossier
(R)-lactic acid
233-713-2 10326-41-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 22-09-2021 View substance registered dossier
Cadmium nitrate 233-710-6 10325-94-7 Active Full Joint ≥ 0 to < 10 tonnes 13-06-2016 View substance registered dossier
Fatty acids, C18-unsatd, dimers, hydrogenated, diisopropyl esters
500-288-2 103213-20-3 Active Full Joint ≥ 10 to < 100 tonnes 17-09-2019 View substance registered dossier
L-Proline, 4-cyclohexyl-, (4S)-
600-406-3 103201-78-1 Active Intermediate Individual Intermediate use only 24-02-2010 View substance registered dossier
2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione
233-701-7 10319-14-9 Active Full Joint ≥ 10 to < 100 tonnes 09-06-2021 View substance registered dossier
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime
500-287-7 103170-26-9 Active Full Joint ≥ 1 000 to < 10 000 tonnes 21-08-2019 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-780-1 103146-25-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
O-isobutyl-N-ethoxy carbonylthiocarbamate
434-350-4 103122-66-3 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride
477-080-2 103121-85-3 Cease Manufacture Full Joint Cease manufacture 08-05-2018 View substance registered dossier
Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride
477-080-2 103121-85-3 Active Intermediate Joint Intermediate use only 22-05-2018 View substance registered dossier
Methyltriphenylphosphonium chloride
METHYL-TPP-CHLORID; MTPP-CHLORID
418-400-2 1031-15-8 Active Full Joint ≥ 1 to < 10 tonnes 20-12-2018 View substance registered dossier
Methyltriphenylphosphonium chloride
METHYL-TPP-CHLORID; MTPP-CHLORID
418-400-2 1031-15-8 Active NONS Individual Tonnage data confidential 23-12-2010 View substance registered dossier
Phenol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-
685-515-4 10309-37-2 Active Full Joint ≥ 1 to < 10 tonnes 05-06-2020 View substance registered dossier
4''-methyl-2'-fluoro-[1,1':4',1''-terphenyl]-4-methanol
813-182-9 1030826-33-5 Active Intermediate Joint Intermediate use only 18-08-2020 View substance registered dossier
N-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl]-2,6-difluorobenzamide
CGA 184699
410-690-9 103055-07-8 Active Full Joint ≥ 100 to < 1 000 tonnes 07-09-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
MITSUI AND CO. ITALIA S.P.A. PIAZZA DEL LIBERTY 2 20121 MILAN Italy Italy Active 2-hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 428-200-7 103577-66-8 2011 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]- 600-451-9 103577-40-8 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]- 600-451-9 103577-40-8 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]- 600-451-9 103577-40-8 - View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 1-[4-(2-dimethylaminoethylsulfonyl)-phenyl-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazole 401-410-6 10357-99-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 2-Naftacencarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-methanoyl-1,11-dioxo-, (4S,4aS,5aR,12aS) 811-443-1 1035655-10-7 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 811-441-0 1035654-66-0 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 6,10-Dioxaspiro[4.5]decane-7-acetic acid, 9-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-, 1,1-dimethylethyl ester, (7R,9R)- 920-205-7 1035204-85-3 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 6,10-Dioxaspiro[4.5]decane-7-acetic acid, 9-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-, 1,1-dimethylethyl ester, (7R,9R)- 920-205-7 1035204-85-3 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 6,10-Dioxaspiro[4.5]decane-7-acetic acid, 9-(cyanomethyl)-, 1,1-dimethylethyl ester, (7R,9R)- 920-979-6 1035204-82-0 2013 View substance registered dossier
[Confidential] - - - Androsta-4,9(11)-diene-3,17-dione 700-663-2 1035-69-4 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester 840-712-6 1034975-53-5 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester 829-017-9 1034975-35-3 - View substance registered dossier
Experien Chemical Services (Europe) Limited PO Box 170 YO7 9AN Thirsk United Kingdom United Kingdom No longer Valid Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 2021 View substance registered dossier
Galata Chemicals GmbH Chemiestrasse 22 68623 Lampertheim 06 Germany Germany No longer Valid Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 2020 View substance registered dossier
Songwon Europe GmbH Nideggener Strasse 213 52349 Düren Germany Germany Active Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 - View substance registered dossier
Labcorp Development SA 046 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 - View substance registered dossier
Reagens S.p.A Via Codronchi 4 40016 San Giorgio di Piano (BO) Italy Italy Active Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 2021 View substance registered dossier
Chemservice S.A. (8LF5) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg No longer Valid Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 2020 View substance registered dossier
REAGENS SPA VIA CODRONCHI, 4 40016 SAN GIORGIO DI PIANO (BO) Italy Italy No longer Valid Reaction products of 3,3'-thiodi(propionic acid) and alcohols, C11-14-iso-, C13-rich 823-780-1 1034820-43-3 2020 View substance registered dossier
Connect Chemicals GmbH Kokkolastr. 2 40882 Ratingen Germany Germany Active 3-tert-butyladipic acid 233-759-3 10347-88-3 2018 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-, (9.beta.,11.beta.)- 600-439-3 103466-44-0 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-, (9.beta.,11.beta.)- 600-439-3 103466-44-0 2017 View substance registered dossier
Chemservice S.A. - (G6T2) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active Graphene 801-282-5 1034343-98-0 2021 View substance registered dossier
DIRECTA PLUS S.p.A. Via Cavour, 2 22074 Lomazzo (CO) Italy Italy Active Graphene 801-282-5 1034343-98-0 2021 View substance registered dossier
Knoell NL_OR_082 Agro Business Park 75 6708 PV Wageningen Netherlands Netherlands Active Graphene 801-282-5 1034343-98-0 - View substance registered dossier
AVANZARE innovacion Tecnologica SL Avenida Lentiscares 4-6 26370 Navarrete LA Rioja Spain Spain Active Graphene 801-282-5 1034343-98-0 2021 View substance registered dossier
Chemservice S.A. - (Z7F6) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active Graphene 801-282-5 1034343-98-0 - View substance registered dossier
Chemservice GmbH - (8UW1) Herrnsheimer Hauptstrasse 1b 67550 Worms Germany Germany Active Graphene 801-282-5 1034343-98-0 2019; 2021 View substance registered dossier
Talga Advanced Materials GmbH Prof.-Hermann-Klare-Straße 25 07407 Rudolstadt Germany Germany Active Graphene 801-282-5 1034343-98-0 2021 View substance registered dossier
Global Graphene Group, Inc. (represented by C.S.B. GmbH) Düsseldorfer Str. 113 47809 Krefeld Germany Germany Active Graphene 801-282-5 1034343-98-0 2020; 2021 View substance registered dossier
Flexegraph AB Viksundsvagen 36 17996 Svartsjo Stockholm Sweden Sweden Active Graphene 801-282-5 1034343-98-0 2021 View substance registered dossier
Chemservice S.A - (AT8I) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active Graphene 801-282-5 1034343-98-0 2019; 2020; 2022 View substance registered dossier
ADVANCED GRAPHENE PRODUCTS S.A. ul. Nowy Kisielin - A. Wysockiego 4 66-002 Zielona Góra Poland Poland Poland Active Graphene 801-282-5 1034343-98-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2-hydroxy-3-(3,4-dimethyl-9-oxo-10-thiaanthracen-2-yloxy)propyl)trimethylammonium chloride 402-200-7 103430-24-6 - View substance registered dossier
Venator P&A Spain S.L. Poligono Industrial Nuevo Puerto Calle A s/n 21810 Palos de la Frontera (Huelva) Spain Spain Active Dititanium tris(sulphate) 233-749-9 10343-61-0 - View substance registered dossier
VENATOR ITALY S.R.L. Localita Casone 1 58020 Scarlino GR Italy Italy Active Dititanium tris(sulphate) 233-749-9 10343-61-0 2017 View substance registered dossier
Venator France SAS 1 Rue des Garennes 62100 Calais France France Active Dititanium tris(sulphate) 233-749-9 10343-61-0 2017 View substance registered dossier
Kuraray Europe GmbH Philipp-Reis-Str. 4 65795 Hattersheim Germany Germany Active 3-Methoxy-3-methylbutyl acetate 700-408-5 103429-90-9 2020 View substance registered dossier
OLEON N.V. Industriezone "ter straten" Vaartstraat 220 2520 Oelegem Belgium Belgium Active Ditetradecyl fumarate 233-739-4 10341-03-4 - View substance registered dossier
Italmatch Chemicals Spa Via Magazzini del Cotone 17 – modulo 4 16128 Genova Italy Italy Active Ditetradecyl fumarate 233-739-4 10341-03-4 2015 View substance registered dossier
BASF Health and Care Products France S.A.S. 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France France Cease Manufacture Ditetradecyl fumarate 233-739-4 10341-03-4 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active Titanium, [2,2-bis[(2-propenyloxy-.kappa.O)methyl]-1-butanolato-.kappa.O]tris(dodecylbenzenesulfonato-.kappa.O)- 418-130-5 103406-74-2 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 3,7-dimethylnona-1,6-dien-3-ol 233-732-6 10339-55-6 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Cease Manufacture 3,7-dimethylnona-1,6-dien-3-ol 233-732-6 10339-55-6 2016 View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 3,7-dimethylnona-1,6-dien-3-ol 233-732-6 10339-55-6 2013; 2019 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 3,7-dimethylnona-1,6-dien-3-ol 233-732-6 10339-55-6 2020 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid 813-635-0 103336-06-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid 813-635-0 103336-06-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 3-oxo-4-aza-5α-androstane-17β-carboxylic acid 407-820-1 103335-55-3 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 3-oxo-4-aza-5α-androstane-17β-carboxylic acid 407-820-1 103335-55-3 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid 407-830-6 103335-54-2 2011; 2021 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid 407-830-6 103335-54-2 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid 407-830-6 103335-54-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid 407-830-6 103335-54-2 - View substance registered dossier
GlaxoSmithKline Services Unlimited 980 Great Western Road TW8 9GS Brentford Middlesex United Kingdom United Kingdom No longer Valid 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid 407-830-6 103335-54-2 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate 600-422-0 103335-41-7 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 1H-Benzimidazole, 2-[[(4-chloro-3-methyl-2-pyridinyl)methyl]thio]- 600-417-3 103312-62-5 - View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 2010 View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom Cease Manufacture L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 2012 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Cease Manufacture L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 2015 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 - View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active L-Proline, N2-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl- 405-650-2 103300-91-0 - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Cease Manufacture N-(N6-trifluoroacetyl-L-lysyl)-L-proline 402-920-1 103300-89-6 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active N-(N6-trifluoroacetyl-L-lysyl)-L-proline 402-920-1 103300-89-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active N-(N6-trifluoroacetyl-L-lysyl)-L-proline 402-920-1 103300-89-6 2010; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active N-(N6-trifluoroacetyl-L-lysyl)-L-proline 402-920-1 103300-89-6 - View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active 2-(3,5-dichloro-2-hydroxyphenyl)quinazolin-4(3H)-one 600-418-9 1033-16-5 2018 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (R)-lactic acid 233-713-2 10326-41-7 - View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (R)-lactic acid 233-713-2 10326-41-7 2021 View substance registered dossier
Flaurea Chemicals SA Quai des usines 12 7800 Ath Hainaut Belgium Belgium Active Cadmium nitrate 233-710-6 10325-94-7 2013; 2016 View substance registered dossier
SAFT SAS 26 Quai Charles Pasqua 92300 LEVALLOIS-PERRET France France Active Cadmium nitrate 233-710-6 10325-94-7 2012; 2016 View substance registered dossier
Lubrizol Europe Coordination Center BVBA 02 Chaussee De Wavre 1945 Brussels Belgium Belgium Active Fatty acids, C18-unsatd, dimers, hydrogenated, diisopropyl esters 500-288-2 103213-20-3 2019 View substance registered dossier
Croda Iberica SA Mevisa Site Carretera C-35 Km 72 (Hostalric-Blanes) 08495 Fogars de la Selva Barcelona Spain Spain Active Fatty acids, C18-unsatd, dimers, hydrogenated, diisopropyl esters 500-288-2 103213-20-3 - View substance registered dossier
Lubrizol Advanced Materials Europe B.V.B.A Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium Belgium Active Fatty acids, C18-unsatd, dimers, hydrogenated, diisopropyl esters 500-288-2 103213-20-3 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active L-Proline, 4-cyclohexyl-, (4S)- 600-406-3 103201-78-1 - View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 - View substance registered dossier
EFI Cretaprint S.L.U Pol. Ind. SUPOI-8 C/Dels Ibers, 54 12550 Almazora Castellon Spain Spain Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 2021 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 - View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 - View substance registered dossier
Reach & Colours Holding Limited BIRCHIN COURT, 20 BIRCHIN LANE EC3V 9DJ LONDON United Kingdom United Kingdom No longer Valid 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 2021 View substance registered dossier
Milliken Europe B.V. Ham 18-24 9000 Gent Belgium Belgium Active 2-(4-bromo-3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione 233-701-7 10319-14-9 - View substance registered dossier
[Confidential] - - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 2014; 2018; 2019 View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 2018 View substance registered dossier
Cytec Industries B.V. OR Weena 505 3013 AL Rotterdam Netherlands Netherlands Cease Manufacture O-isobutyl-N-ethoxy carbonylthiocarbamate 434-350-4 103122-66-3 2018 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride 477-080-2 103121-85-3 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride 477-080-2 103121-85-3 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Active Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride 477-080-2 103121-85-3 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Methyltriphenylphosphonium chloride 418-400-2 1031-15-8 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active Methyltriphenylphosphonium chloride 418-400-2 1031-15-8 - View substance registered dossier
Blue Cube Germany Assets GmbH & Co. KG Buetzflether Sand 2 21683 Stade Germany Germany Active Methyltriphenylphosphonium chloride 418-400-2 1031-15-8 2010 View substance registered dossier
Sytheon France 112 rue de Paris 92100 Boulogne Billancourt France France Active Phenol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]- 685-515-4 10309-37-2 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4''-methyl-2'-fluoro-[1,1':4',1''-terphenyl]-4-methanol 813-182-9 1030826-33-5 - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active N-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl]-2,6-difluorobenzamide 410-690-9 103055-07-8 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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