Registered substances

Registered substances

Registered substances

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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, 1-methylethyl ester
935-121-6 1253789-90-0 Cease Manufacture Intermediate Joint Cease manufacture 22-04-2013 View substance registered dossier
1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, methyl ester
690-920-4 494799-38-1 Cease Manufacture Intermediate Joint Cease manufacture 22-04-2013 View substance registered dossier
1H-Isoindol-1-one, 2,3-dihydro-3,3-bis(4-hydroxyphenyl)-2-phenyl-
455-890-7 6607-41-6 Active Full Individual Tonnage data confidential 23-07-2015 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)-
616-149-5 74860-00-7 Active Intermediate Joint Intermediate use only 28-11-2019 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-(3R)-3-piperidinyl-, (2S,3S)-2,3-dihydroxybutanedioate (1:1)
692-713-4 886588-62-1 Active Intermediate Joint Intermediate use only 20-12-2019 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
610-200-5 446292-07-5 Active Intermediate Individual Intermediate use only 21-08-2018 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]-
454-720-9 161596-47-0 Active Intermediate Individual Intermediate use only 02-07-2010 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]-
454-720-9 161596-47-0 Active Intermediate Joint Intermediate use only 16-06-2021 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-
607-813-5 25830-77-7 Active Full Joint ≥ 1 to < 10 tonnes 22-03-2018 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-
629-841-7 143878-20-0 Active Intermediate Individual Intermediate use only 31-10-2016 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-
420-030-1 143878-20-0 Active Intermediate Individual Intermediate use only 18-07-2011 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-
420-030-1 143878-20-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-
420-030-1 143878-20-0 Active Intermediate Joint Intermediate use only 24-05-2022 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
610-201-0 446292-08-6 Active Intermediate Joint Intermediate use only 06-08-2021 View substance registered dossier
1H-Perylo[3,4-cd]pyridine-1,3(2H)-dione
608-929-9 33955-44-1 Active Intermediate Individual Intermediate use only 01-12-2014 View substance registered dossier
1H-Perylo[3,4-cd]pyridine-8,9-dicarboxylic acid, 2,3-dihydro-1,3-dioxo-, potassium salt (1:2)
807-752-6 1451734-05-6 Active Intermediate Individual Intermediate use only 17-07-2017 View substance registered dossier
1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-7-propyl-
611-243-2 55242-64-3 Active Intermediate Joint Intermediate use only 13-12-2016 View substance registered dossier
1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-[(3R)-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-piperidinyl]-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-
937-756-4 886588-63-2 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-
613-975-8 666816-98-4 Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-
922-028-0 853029-57-9 Active Intermediate Joint Intermediate use only 23-01-2017 View substance registered dossier
1H-Pyrazole, 1,4-dimethyl-
600-813-6 1072-68-0 Active Intermediate Joint Intermediate use only 23-11-2016 View substance registered dossier
1H-Pyrazole, 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
689-230-6 1029716-44-6 Active Intermediate Individual Intermediate use only 19-06-2017 View substance registered dossier
1H-Pyrazole, 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
689-230-6 1029716-44-6 Active Intermediate Joint Intermediate use only 06-04-2020 View substance registered dossier
1H-Pyrazole, 1-(tetrahydro-2H-pyran-2-yl)-
807-897-5 449758-17-2 Active Intermediate Joint Intermediate use only 10-11-2022 View substance registered dossier
1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1)
424-640-9 202842-98-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1)
424-640-9 202842-98-6 Active Full Joint ≥ 100 tonnes 16-07-2021 View substance registered dossier
1H-Pyrazole-1-carbothioic acid, 5-amino-2,3-dihydro-4-(2-methylphenyl)-3-oxo-, S-2-propen-1-yl ester
700-691-5 473799-16-5 Cease Manufacture Intermediate Individual Cease manufacture 18-11-2011 View substance registered dossier
1H-Pyrazole-3,5-dicarboxylic acid, 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-, 3,5-diethyl ester
603-923-2 135590-91-9 Active Full Joint ≥ 100 to < 1 000 tonnes 19-05-2022 View substance registered dossier
1H-Pyrazole-3-carbonitrile, 4,4'-dithiobis[5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-
603-434-4 130755-46-3 Active Intermediate Joint Intermediate use only 20-09-2017 View substance registered dossier
1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-, reaction products with guanidine hydrochloride N,N'-bis(mixed Ph, tolyl and xylyl) derivs.
275-170-4 71077-14-0 Active Full Joint ≥ 1 to < 10 tonnes 06-03-2018 View substance registered dossier
1H-pyrazole-3-carboxylic acid, 4-[[5-[[4,6-bis[(3-sulfopropyl)thio]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]azo]-1-(2,5-dichloro-4-sulfophenyl)-4,5-dihydro-5-oxo-, pentasodium salt
COLORANT Y-178; DYE Y-178; Y-178
456-170-5 187674-76-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester
805-733-7 256504-39-9 Active Intermediate Joint Intermediate use only 21-07-2022 View substance registered dossier
1H-Pyrazole-4-carbonyl chloride, 3-(difluoromethyl)-1-methyl-
619-511-0 141573-96-8 Active Intermediate Joint Intermediate use only 31-05-2021 View substance registered dossier
1H-Pyrazole-4-carbonyl chloride, 5-chloro-1,3-dimethyl-
608-031-7 27006-83-3 Active Intermediate Joint Intermediate use only 15-05-2020 View substance registered dossier
1H-Pyrazole-4-carbonyl fluoride, 5-fluoro-1,3-dimethyl-
619-796-1 191614-02-5 Active Intermediate Joint Intermediate use only 17-01-2018 View substance registered dossier
1H-Pyrazole-4-carboxylic acid, 3-(difluoromethyl)-1-methyl-, ethyl ester
619-510-5 141573-95-7 Active Intermediate Individual Intermediate use only 13-04-2012 View substance registered dossier
1H-Pyrazole-5-carboxamide, 4-[[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzoyl]amino]-1-methyl-3-propyl-
639-263-7 200575-15-1 Active Intermediate Individual Intermediate use only 12-04-2017 View substance registered dossier
1H-Pyrazole-5-carboxamide, 4-amino-1-methyl-3-propyl-, hydrochloride (1:?)
938-723-7 1688656-88-3 Active Intermediate Joint Intermediate use only 19-07-2021 View substance registered dossier
1H-Pyrazole-5-carboxamide,4-amino-1-methyl-3-propyl-, hydrochloride
607-432-4 247584-10-7 Active Intermediate Individual Intermediate use only 31-05-2018 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-3-(hydroxymethyl)-, methyl ester
937-132-1 960316-73-8 Active Intermediate Individual Intermediate use only 02-09-2016 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-3-[[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl]-
936-882-7 1352319-02-8 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-4,5-dihydro-5-hydroxy-3-(hydroxymethyl)-, methyl ester
936-349-9 1312304-36-1 Active Intermediate Individual Intermediate use only 17-09-2015 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 3-(chloromethyl)-1-(3-chloro-2-pyridinyl)-, methyl ester
936-879-0 1247712-63-5 Active Intermediate Individual Intermediate use only 17-02-2017 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-
481-150-8 500011-86-9 Active Full Individual ≥ 1 to < 10 tonnes 13-08-2020 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-
481-150-8 500011-86-9 Active Intermediate Joint Intermediate use only 04-12-2020 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-, ethyl ester
610-491-9 500011-92-7 Active Intermediate Joint Intermediate use only 08-10-2020 View substance registered dossier
1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-4,5-dihydro-, ethyl ester
805-389-8 500011-91-6 Active Intermediate Joint Intermediate use only 21-09-2020 View substance registered dossier
1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]-
811-889-7 1350653-26-7 Active Intermediate Joint Intermediate use only 18-07-2022 View substance registered dossier
1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 5-fluoro-1-[(2-fluorophenyl)methyl]-
811-886-0 1361232-73-6 Active Intermediate Joint Intermediate use only 18-07-2022 View substance registered dossier
1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 5-fluoro-1-[(2-fluorophenyl)methyl]-
811-931-4 1350653-27-8 Active Intermediate Joint Intermediate use only 01-08-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture 1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, 1-methylethyl ester 935-121-6 1253789-90-0 2014 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, 1-methylethyl ester 935-121-6 1253789-90-0 2014 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, methyl ester 690-920-4 494799-38-1 2014 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture 1H-Indole-6-carboxylic acid, 3-cyclopentyl-1-methyl-, methyl ester 690-920-4 494799-38-1 2014 View substance registered dossier
SHPP B.V. Plasticslaan 1 4612PX Bergen op Zoom Netherlands Netherlands Active 1H-Isoindol-1-one, 2,3-dihydro-3,3-bis(4-hydroxyphenyl)-2-phenyl- 455-890-7 6607-41-6 2012; 2015 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)- 616-149-5 74860-00-7 2019 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)- 616-149-5 74860-00-7 2019 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-(3R)-3-piperidinyl-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) 692-713-4 886588-62-1 2016; 2019 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-(3R)-3-piperidinyl-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) 692-713-4 886588-62-1 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1H-Isoindole-1,3(2H)-dione, 2-(3R)-3-piperidinyl-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) 692-713-4 886588-62-1 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]- 610-200-5 446292-07-5 2012; 2018 View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]- 454-720-9 161596-47-0 2010 View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]- 454-720-9 161596-47-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]- 454-720-9 161596-47-0 2010; 2020 View substance registered dossier
Chemsafe Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Active 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]- 454-720-9 161596-47-0 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]- 607-813-5 25830-77-7 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]- 629-841-7 143878-20-0 - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]- 420-030-1 143878-20-0 - View substance registered dossier
- - - - 1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]- 420-030-1 143878-20-0 - View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]- 420-030-1 143878-20-0 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- 610-201-0 446292-08-6 - View substance registered dossier
Medichem Manufacturing (Malta) Limited HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta Malta Active 1H-Isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- 610-201-0 446292-08-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- 610-201-0 446292-08-6 2012; 2018; 2020 View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 1H-Perylo[3,4-cd]pyridine-1,3(2H)-dione 608-929-9 33955-44-1 - View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 1H-Perylo[3,4-cd]pyridine-8,9-dicarboxylic acid, 2,3-dihydro-1,3-dioxo-, potassium salt (1:2) 807-752-6 1451734-05-6 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-7-propyl- 611-243-2 55242-64-3 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-[(3R)-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-piperidinyl]-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- 937-756-4 886588-63-2 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-[(3R)-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-piperidinyl]-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- 937-756-4 886588-63-2 2017 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl- 613-975-8 666816-98-4 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl- 613-975-8 666816-98-4 2016; 2019 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- 922-028-0 853029-57-9 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- 922-028-0 853029-57-9 2017 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1H-Pyrazole, 1,4-dimethyl- 600-813-6 1072-68-0 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 1H-Pyrazole, 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 689-230-6 1029716-44-6 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 1H-Pyrazole, 1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 689-230-6 1029716-44-6 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 1H-Pyrazole, 1-(tetrahydro-2H-pyran-2-yl)- 807-897-5 449758-17-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1H-Pyrazole, 1-(tetrahydro-2H-pyran-2-yl)- 807-897-5 449758-17-2 2015; 2017; 2022 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 1H-Pyrazole, 1-(tetrahydro-2H-pyran-2-yl)- 807-897-5 449758-17-2 - View substance registered dossier
EuroChem Antwerpen NV Haven 725, Scheldelaan 600 2040 Antwerp Belgium Belgium Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 - View substance registered dossier
AGRODERIVADOS Y QUÍMICOS WEGROW, SL C/ Villalar, 4, 1º derecha 28001 Madrid Spain Spain Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 2020; 2021 View substance registered dossier
COMPO Expert GmbH Krögerweg 10 48155 Münster NRW Germany Germany Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 2020 View substance registered dossier
MUGAVERO S.P.A. Via Giovanni Marradi 1 20123 MILANO Italy Italy Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 - View substance registered dossier
DeltaChem GmbH Gildenstrasse 36 D-48157 Münster Germany Germany Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 2019 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1H-Pyrazole, 3,4-dimethyl-, phosphate (1:1) 424-640-9 202842-98-6 2018; 2021 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture 1H-Pyrazole-1-carbothioic acid, 5-amino-2,3-dihydro-4-(2-methylphenyl)-3-oxo-, S-2-propen-1-yl ester 700-691-5 473799-16-5 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-3,5-dicarboxylic acid, 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-, 3,5-diethyl ester 603-923-2 135590-91-9 2011; 2014; 2015; 2016; 2019 View substance registered dossier
Helm AG Nordkanalstraße 28 20097 Hamburg Germany Germany Active 1H-Pyrazole-3,5-dicarboxylic acid, 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-, 3,5-diethyl ester 603-923-2 135590-91-9 - View substance registered dossier
Przedsiębiorstwo Usługowo-Handlowe "CHEMIROL" Sp z o.o. ul. Przemysłowa 3 88-300 Mogilno Poland Poland Poland Active 1H-Pyrazole-3,5-dicarboxylic acid, 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-, 3,5-diethyl ester 603-923-2 135590-91-9 - View substance registered dossier
BASF Agri Production SAS 21 Rue de la Sauvegarde 69130 Ecully Rhone France France Active 1H-Pyrazole-3-carbonitrile, 4,4'-dithiobis[5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]- 603-434-4 130755-46-3 2010; 2012; 2017 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-, reaction products with guanidine hydrochloride N,N'-bis(mixed Ph, tolyl and xylyl) derivs. 275-170-4 71077-14-0 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 1H-pyrazole-3-carboxylic acid, 4-[[5-[[4,6-bis[(3-sulfopropyl)thio]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]azo]-1-(2,5-dichloro-4-sulfophenyl)-4,5-dihydro-5-oxo-, pentasodium salt 456-170-5 187674-76-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester 805-733-7 256504-39-9 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester 805-733-7 256504-39-9 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester 805-733-7 256504-39-9 2016 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-3-carboxylic acid, 5-amino-1-[(2-fluorophenyl)methyl]-, ethyl ester 805-733-7 256504-39-9 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-4-carbonyl chloride, 3-(difluoromethyl)-1-methyl- 619-511-0 141573-96-8 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1H-Pyrazole-4-carbonyl chloride, 3-(difluoromethyl)-1-methyl- 619-511-0 141573-96-8 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1H-Pyrazole-4-carbonyl chloride, 5-chloro-1,3-dimethyl- 608-031-7 27006-83-3 2012; 2016; 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-4-carbonyl fluoride, 5-fluoro-1,3-dimethyl- 619-796-1 191614-02-5 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 1H-Pyrazole-4-carbonyl fluoride, 5-fluoro-1,3-dimethyl- 619-796-1 191614-02-5 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1H-Pyrazole-4-carbonyl fluoride, 5-fluoro-1,3-dimethyl- 619-796-1 191614-02-5 - View substance registered dossier
M2I SALIN 112 bureaux de la colline 92213 St Cloud France France Active 1H-Pyrazole-4-carboxylic acid, 3-(difluoromethyl)-1-methyl-, ethyl ester 619-510-5 141573-95-7 2012 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 1H-Pyrazole-5-carboxamide, 4-[[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzoyl]amino]-1-methyl-3-propyl- 639-263-7 200575-15-1 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 1H-Pyrazole-5-carboxamide, 4-amino-1-methyl-3-propyl-, hydrochloride (1:?) 938-723-7 1688656-88-3 2019; 2021 View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 1H-Pyrazole-5-carboxamide,4-amino-1-methyl-3-propyl-, hydrochloride 607-432-4 247584-10-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-3-(hydroxymethyl)-, methyl ester 937-132-1 960316-73-8 2016 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-3-[[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl]- 936-882-7 1352319-02-8 2016; 2017 View substance registered dossier
[Confidential] - - - 1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-3-[[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl]- 936-882-7 1352319-02-8 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-5-carboxylic acid, 1-(3-chloro-2-pyridinyl)-4,5-dihydro-5-hydroxy-3-(hydroxymethyl)-, methyl ester 936-349-9 1312304-36-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazole-5-carboxylic acid, 3-(chloromethyl)-1-(3-chloro-2-pyridinyl)-, methyl ester 936-879-0 1247712-63-5 2017 View substance registered dossier
Chemical Company SA B-dul Chimiei 14 700293 Iasi Iasi Romania Romania Active 1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)- 481-150-8 500011-86-9 - View substance registered dossier
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark No longer Valid 1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)- 481-150-8 500011-86-9 - View substance registered dossier
[Confidential] - - - 1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)- 481-150-8 500011-86-9 - View substance registered dossier
[Confidential] - - - 1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-, ethyl ester 610-491-9 500011-92-7 - View substance registered dossier
[Confidential] - - - 1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-4,5-dihydro-, ethyl ester 805-389-8 500011-91-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-889-7 1350653-26-7 2020; 2021; 2022 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-889-7 1350653-26-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-886-0 1361232-73-6 2020; 2021; 2022 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active 1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-886-0 1361232-73-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-931-4 1350653-27-8 2020; 2021; 2022 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active 1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 5-fluoro-1-[(2-fluorophenyl)methyl]- 811-931-4 1350653-27-8 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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