Registered substances

Registered substances

Registered substances

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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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1-Propanamine, 3-(methoxydimethylsilyl)-
608-570-8 31024-26-7 Active Intermediate Joint Intermediate use only 04-02-2019 View substance registered dossier
1-Propanamine, 3-(methoxydimethylsilyl)-
608-570-8 31024-26-7 Cease Manufacture Intermediate Individual Cease manufacture 14-05-2012 View substance registered dossier
1-Propanaminium, 3-(aminocarbonyl)-2-hydroxy-N,N,N-trimethyl-, (1R,3S)-1,2,2-trimethyl-1,3-cyclopentanedicarboxylate (1:1)
925-384-5 90639-98-8 Active Intermediate Individual Intermediate use only 29-01-2014 View substance registered dossier
1-Propanaminium, 3-bromo-N,N,N-trimethyl-, bromide (1:1)
628-915-6 3779-42-8 No longer Valid Intermediate Individual No longer valid 05-05-2015 View substance registered dossier
1-Propanaminium, 3-bromo-N,N,N-trimethyl-, bromide (1:1)
628-915-6 3779-42-8 Active Intermediate Joint Intermediate use only 21-12-2018 View substance registered dossier
1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-
806-749-7 918504-27-5 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-
806-798-4 1262985-23-8 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-
806-756-5 1262985-24-9 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanesulfonyl chloride, 3-[(3,4-dicyanophenyl)sulfonyl]-
610-401-8 480427-96-1 No longer Valid Intermediate Individual No longer valid 03-04-2017 View substance registered dossier
1-Propanol, 1-bromo-2-methyl-, 1-propanoate
605-166-3 158894-67-8 Active Intermediate Individual Intermediate use only 20-12-2017 View substance registered dossier
1-Propanol, 3-(dimethylamino)-, hydrochloride (1:1)
601-495-1 117829-74-0 Active Intermediate Individual Intermediate use only 02-08-2011 View substance registered dossier
1-Propanol, 3-(methylsulfonyl)-, 1-(4-methylbenzenesulfonate)
809-900-5 263400-88-0 Active Intermediate Joint Intermediate use only 07-09-2018 View substance registered dossier
1-Propanone, 1-(3-phenylcyclohexyl)-
929-116-8 1178536-76-9 Cease Manufacture Intermediate Individual Cease manufacture 11-12-2012 View substance registered dossier
1-Propanone, 1-(4-chlorophenyl)-2-cyclopropyl-
602-964-3 123989-29-7 Active Intermediate Individual Intermediate use only 12-06-2012 View substance registered dossier
1-Propanone, 1-(4-cyclohexylphenyl)-
611-869-6 59721-67-4 Cease Manufacture Intermediate Joint Cease manufacture 11-12-2012 View substance registered dossier
1-Propanone, 1-(4-phenylcyclohexyl)-
608-991-7 344348-40-9 Cease Manufacture Intermediate Joint Cease manufacture 11-12-2012 View substance registered dossier
1-Propanone, 1-(4-phenylcyclohexyl)-, trans-
618-109-2 88069-93-6 Cease Manufacture Intermediate Joint Cease manufacture 13-11-2017 View substance registered dossier
1-Propanone, 1-[2-(2-propen-1-yloxy)phenyl]-
604-312-3 142819-94-1 Active Intermediate Individual Intermediate use only 21-09-2015 View substance registered dossier
1-Propanone, 2-[(2-hydroxyethyl)methylamino]-1-phenyl-
618-508-1 902267-47-4 Active Intermediate Joint Intermediate use only 08-06-2016 View substance registered dossier
1-Propanone, 2-chloro-1-(4-chlorophenyl)-
810-506-0 877-38-3 Active Intermediate Individual Intermediate use only 07-08-2015 View substance registered dossier
1-Propanone, 2-methyl-1-[4-(methylthio)phenyl]-
610-979-1 53207-58-2 Active Intermediate Individual Intermediate use only 26-05-2010 View substance registered dossier
1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1)
609-494-8 37951-53-4 Active Intermediate Joint Intermediate use only 31-08-2018 View substance registered dossier
1-Propen-1,2,3-tricarbonsäure tris(2-(2,2,3,3,3,4,4,4-heptafluorbutoxy)-1-(methyl)-ethyl)ester
943-789-5 1449567-31-0 Active Intermediate Joint Intermediate use only 09-06-2021 View substance registered dossier
1-Propene, 1-methoxy-
615-927-1 7319-16-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
1-Propene, 2-chloro-3-isothiocyanato-
604-275-3 14214-31-4 Active Intermediate Individual Intermediate use only 29-11-2010 View substance registered dossier
1-Propene, 2-methyl-, chlorinated, epoxidized, distn. residues
304-801-9 94279-55-7 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
1-Propene, 2-methyl-, pentamer
610-010-2 42278-27-3 Active Intermediate Joint Intermediate use only 21-01-2022 View substance registered dossier
1-Propene, chlorinated, epoxidized, distn. residues
304-800-3 94279-54-6 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
1-Propene, hydroformulation products, by-products from, distillation residues
606-535-1 203588-70-9 Active Intermediate Joint Intermediate use only 23-03-2021 View substance registered dossier
1-Propene, hydroformylation products, high-boiling
A complex combination of products produced by the distillation of products from the hydrogenation of butanal from the hydroformylation of propene. It consists predominantly of organic compounds such as aldehydes, alcohols, esters, ethers and carboxylic acids having carbon numbers in the range of C4-C32 and boiling in the range of approximately 143°C to 282°C (289°F to 540°F).
271-363-2 68551-11-1 Active Intermediate Individual Intermediate use only 19-10-2010 View substance registered dossier
1-propylbutylamine
240-814-5 16751-59-0 Active Intermediate Joint Intermediate use only 18-10-2021 View substance registered dossier
1-Pyrrolidineacetamide, .alpha.-ethyl-2-oxo-
446-650-2 33996-58-6 Cease Manufacture Intermediate Individual Cease manufacture 01-10-2012 View substance registered dossier
1-Pyrrolidineacetamide, N-[(diethylamino)methyl]-.alpha.-ethyl-2-oxo-, (.alpha.S)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
700-272-7 754186-36-2 Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2,2'-[[(2R,5R)-1-[3,5-difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]phenyl]-2,5-pyrrolidinediyl]bis[(2-amino-5-fluoro-4,1-phenylene)iminocarbonyl]]bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)-
945-018-8 2151870-61-8 Active Intermediate Joint Intermediate use only 06-06-2017 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2,2'-[[(6S)-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]di-1H-imidazole-5,2-diyl]bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)-
813-165-6 1369595-05-0 Active Intermediate Individual Intermediate use only 26-09-2016 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2-(5-bromo-1H-imidazol-2-yl)-, 1,1-dimethylethyl ester, (2S)-
813-157-2 1007882-59-8 Active Intermediate Individual Intermediate use only 26-09-2016 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)-
807-100-0 1378391-45-7 Active Intermediate Individual Intermediate use only 28-09-2016 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2-[5-[4'-[2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-1H-imidazol-5-yl][1,1'-biphenyl]-4-yl]-1H-pyrazol-3-yl]-, 1,1-dimethylethyl ester, (2S)-
941-432-8 1085706-46-2 Active Intermediate Individual Intermediate use only 26-09-2014 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 3-[2-[(ethoxycarbonyl)[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-, phenylmethyl ester, (3R,4S)-
944-343-2 2050038-81-6 Active Intermediate Joint Intermediate use only 03-12-2021 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)-
604-254-9 141818-73-7 Active Intermediate Joint Intermediate use only 06-07-2021 View substance registered dossier
1-Pyrrolidinecarboxylic acid,2-[(dimethylamino)carbonyl]-4-mercapto-,2-propen-1-yl ester, (2S,4S)- and methyl benzoate
942-819-4 - Active Intermediate Joint Intermediate use only 07-10-2019 View substance registered dossier
1-Pyrrolidinepropanoic acid, 2-carboxy-.alpha.-(1,1-dimethylethyl)-4-hydroxy-.beta.-oxo-, 1-(1,1-dimethylethyl) ester, (.alpha.S,2S,4R)-, compd. with tetrahydrofuran (1:1)
941-817-0 1690340-81-8 Active Intermediate Individual Intermediate use only 10-02-2015 View substance registered dossier
1-tert-butoxycarbonylpiperidine-4-carboxylic acid
700-076-1 84358-13-4 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
1-Tetradecanaminium, N,N,N-trimethyl-, methyl carbonate (1:1)
807-015-9 126437-91-0 Active Intermediate Individual Intermediate use only 01-06-2016 View substance registered dossier
1-{4-[2-(benzyloxy)ethoxy]phenyl}-1,2-diphenylbutane-1,4-diol
939-875-7 - Active Intermediate Joint Intermediate use only 30-07-2021 View substance registered dossier
1-β-D-arabinofuranosylcytosine hydrochloride
200-713-9 69-74-9 Active Intermediate Joint Intermediate use only 12-12-2017 View substance registered dossier
10,10-dimethylanthracen-9(10H)-one
226-666-4 5447-86-9 Active Intermediate Joint Intermediate use only 03-07-2020 View substance registered dossier
10,11-dihydro-5H-dibenz[b,f]azepine
207-787-1 494-19-9 Active Intermediate Individual Intermediate use only 29-07-2010 View substance registered dossier
10,11-dihydro-5H-dibenz[b,f]azepine
207-787-1 494-19-9 Active Intermediate Joint Intermediate use only 31-01-2020 View substance registered dossier
10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine
201-578-9 84-97-9 Active Intermediate Individual Intermediate use only 23-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 2012; 2015 View substance registered dossier
[Confidential] - - - 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 2019 View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active 1-Propanaminium, 3-(aminocarbonyl)-2-hydroxy-N,N,N-trimethyl-, (1R,3S)-1,2,2-trimethyl-1,3-cyclopentanedicarboxylate (1:1) 925-384-5 90639-98-8 - View substance registered dossier
Nalco Limited P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom United Kingdom No longer Valid 1-Propanaminium, 3-bromo-N,N,N-trimethyl-, bromide (1:1) 628-915-6 3779-42-8 2021 View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active 1-Propanaminium, 3-bromo-N,N,N-trimethyl-, bromide (1:1) 628-915-6 3779-42-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- 806-749-7 918504-27-5 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- 806-749-7 918504-27-5 2020; 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-798-4 1262985-23-8 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-798-4 1262985-23-8 2021 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-756-5 1262985-24-9 2020; 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-756-5 1262985-24-9 - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid 1-Propanesulfonyl chloride, 3-[(3,4-dicyanophenyl)sulfonyl]- 610-401-8 480427-96-1 2021 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 1-Propanol, 1-bromo-2-methyl-, 1-propanoate 605-166-3 158894-67-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propanol, 3-(dimethylamino)-, hydrochloride (1:1) 601-495-1 117829-74-0 2011 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active 1-Propanol, 3-(methylsulfonyl)-, 1-(4-methylbenzenesulfonate) 809-900-5 263400-88-0 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 1-Propanone, 1-(3-phenylcyclohexyl)- 929-116-8 1178536-76-9 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1-Propanone, 1-(4-chlorophenyl)-2-cyclopropyl- 602-964-3 123989-29-7 2012 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 1-Propanone, 1-(4-cyclohexylphenyl)- 611-869-6 59721-67-4 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 1-Propanone, 1-(4-phenylcyclohexyl)- 608-991-7 344348-40-9 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 1-Propanone, 1-(4-phenylcyclohexyl)-, trans- 618-109-2 88069-93-6 2019 View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-Propanone, 1-[2-(2-propen-1-yloxy)phenyl]- 604-312-3 142819-94-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1-Propanone, 2-[(2-hydroxyethyl)methylamino]-1-phenyl- 618-508-1 902267-47-4 - View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active 1-Propanone, 2-chloro-1-(4-chlorophenyl)- 810-506-0 877-38-3 2015 View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active 1-Propanone, 2-methyl-1-[4-(methylthio)phenyl]- 610-979-1 53207-58-2 - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active 1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1) 609-494-8 37951-53-4 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 1-Propen-1,2,3-tricarbonsäure tris(2-(2,2,3,3,3,4,4,4-heptafluorbutoxy)-1-(methyl)-ethyl)ester 943-789-5 1449567-31-0 - View substance registered dossier
[Confidential] - - - 1-Propene, 1-methoxy- 615-927-1 7319-16-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1-Propene, 2-chloro-3-isothiocyanato- 604-275-3 14214-31-4 2010 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, 2-methyl-, chlorinated, epoxidized, distn. residues 304-801-9 94279-55-7 - View substance registered dossier
INEOS Manufacturing Deutschland GmbH Alte Strasse 201 50769 Koeln Germany Germany Active 1-Propene, 2-methyl-, pentamer 610-010-2 42278-27-3 2020; 2022 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, chlorinated, epoxidized, distn. residues 304-800-3 94279-54-6 - View substance registered dossier
INEOS Derivatives Lavera SAS (Oxide) Avenue de la bienfaisance BP6 133117 Lavera France France Active 1-Propene, hydroformulation products, by-products from, distillation residues 606-535-1 203588-70-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, hydroformylation products, high-boiling 271-363-2 68551-11-1 - View substance registered dossier
[Confidential] - - - 1-propylbutylamine 240-814-5 16751-59-0 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture 1-Pyrrolidineacetamide, .alpha.-ethyl-2-oxo- 446-650-2 33996-58-6 2017 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 1-Pyrrolidineacetamide, N-[(diethylamino)methyl]-.alpha.-ethyl-2-oxo-, (.alpha.S)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) 700-272-7 754186-36-2 2008; 2010; 2012; 2015 View substance registered dossier
[Confidential] - - - 1-Pyrrolidinecarboxylic acid, 2,2'-[[(2R,5R)-1-[3,5-difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]phenyl]-2,5-pyrrolidinediyl]bis[(2-amino-5-fluoro-4,1-phenylene)iminocarbonyl]]bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)- 945-018-8 2151870-61-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Pyrrolidinecarboxylic acid, 2,2'-[[(6S)-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]di-1H-imidazole-5,2-diyl]bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)- 813-165-6 1369595-05-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Pyrrolidinecarboxylic acid, 2-(5-bromo-1H-imidazol-2-yl)-, 1,1-dimethylethyl ester, (2S)- 813-157-2 1007882-59-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Pyrrolidinecarboxylic acid, 2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)- 807-100-0 1378391-45-7 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active 1-Pyrrolidinecarboxylic acid, 2-[5-[4'-[2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-1H-imidazol-5-yl][1,1'-biphenyl]-4-yl]-1H-pyrazol-3-yl]-, 1,1-dimethylethyl ester, (2S)- 941-432-8 1085706-46-2 - View substance registered dossier
[Confidential] - - - 1-Pyrrolidinecarboxylic acid, 3-[2-[(ethoxycarbonyl)[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-, phenylmethyl ester, (3R,4S)- 944-343-2 2050038-81-6 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 - View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 2021 View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1-Pyrrolidinecarboxylic acid,2-[(dimethylamino)carbonyl]-4-mercapto-,2-propen-1-yl ester, (2S,4S)- and methyl benzoate 942-819-4 - 2019 View substance registered dossier
[Confidential] - - - 1-Pyrrolidinepropanoic acid, 2-carboxy-.alpha.-(1,1-dimethylethyl)-4-hydroxy-.beta.-oxo-, 1-(1,1-dimethylethyl) ester, (.alpha.S,2S,4R)-, compd. with tetrahydrofuran (1:1) 941-817-0 1690340-81-8 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 1-tert-butoxycarbonylpiperidine-4-carboxylic acid 700-076-1 84358-13-4 - View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany Germany Active 1-Tetradecanaminium, N,N,N-trimethyl-, methyl carbonate (1:1) 807-015-9 126437-91-0 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 1-{4-[2-(benzyloxy)ethoxy]phenyl}-1,2-diphenylbutane-1,4-diol 939-875-7 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1-{4-[2-(benzyloxy)ethoxy]phenyl}-1,2-diphenylbutane-1,4-diol 939-875-7 - 2017 View substance registered dossier
ARCHIMICA S.P.A. Viale Milano 86 26900 Lodi Italy Italy Italy Active 1-β-D-arabinofuranosylcytosine hydrochloride 200-713-9 69-74-9 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active 10,10-dimethylanthracen-9(10H)-one 226-666-4 5447-86-9 2020 View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 10,10-dimethylanthracen-9(10H)-one 226-666-4 5447-86-9 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Chemosyntha BV Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium Belgium Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
SAFIC ALCAN 13 Cours Valmy 92977 Paris La Défense France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Kemikos s.r.l. Via Carolina Romani, 2/A 20091 Bresso (MI) Italy Italy Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 201-578-9 84-97-9 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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