Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1)
639-694-0 188416-20-8 Active Intermediate Joint Intermediate use only 04-05-2015 View substance registered dossier
4-Quinazolinamine, 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitro-
810-185-7 179552-73-9 Active Intermediate Joint Intermediate use only 23-06-2015 View substance registered dossier
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)-
620-069-6 945553-94-6 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
925-395-5 314771-88-5 Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
4-Sulfonamidophenylhydrazine hydrochloride
605-823-4 17852-52-7 Active Intermediate Joint Intermediate use only 21-05-2018 View substance registered dossier
4-tert-butyl-2,6-dinitrochlorobenzene
218-672-0 2213-81-2 Active Intermediate Joint Intermediate use only 24-05-2018 View substance registered dossier
4-tert-butyl-3-hydroxy-2,6-xylylacetonitrile
259-766-1 55699-10-0 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
4-tert-butylbenzaldehyde
213-367-9 939-97-9 Active Intermediate Individual Intermediate use only 14-08-2013 View substance registered dossier
4-tert-butylbenzaldehyde
213-367-9 939-97-9 Active Intermediate Joint Intermediate use only 16-09-2010 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 15-08-2013 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Joint Intermediate use only 28-03-2018 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 27-11-2012 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 13-04-2015 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 31-03-2015 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 30-11-2010 View substance registered dossier
4-tert-butylbenzonitrile
224-137-2 4210-32-6 Active Intermediate Joint Intermediate use only 24-07-2020 View substance registered dossier
4-tert-butylbenzylamine
254-681-6 39895-55-1 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
4-tert-butylcyclohex-1-ene
606-973-3 2228-98-0 Active Intermediate Joint Intermediate use only 09-04-2018 View substance registered dossier
4-tert-butylcyclohexanol
202-676-4 98-52-2 Active Intermediate Joint Intermediate use only 13-01-2020 View substance registered dossier
4-tert-butyltoluene
202-675-9 98-51-1 Active Intermediate Joint Intermediate use only 15-10-2021 View substance registered dossier
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-
618-303-7 89786-04-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, (2S,3S,5R)-
618-304-2 89789-07-1 Active Intermediate Joint Intermediate use only 13-03-2018 View substance registered dossier
4-Thiazoleacetic acid, 2-(formylamino)-α-oxo-
613-733-1 64987-06-0 Active Intermediate Individual Intermediate use only 27-10-2017 View substance registered dossier
4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-, hydrochloride (1:2)
937-695-3 1185167-55-8 Active Intermediate Individual Intermediate use only 31-07-2012 View substance registered dossier
4-THIAZOLIDINE CARBOXYLIC ETHYL ESTER HCl
613-908-2 66223-38-9 Active Intermediate Individual Intermediate use only 18-01-2018 View substance registered dossier
4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd
604-491-8 145767-92-6 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-vinylcyclohexene
202-848-9 100-40-3 Active Intermediate Joint Intermediate use only 11-07-2017 View substance registered dossier
4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid
926-027-6 - Active Intermediate Joint Intermediate use only 08-07-2019 View substance registered dossier
4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one
828-315-6 1443532-21-5 Active Intermediate Individual Intermediate use only 22-11-2019 View substance registered dossier
4H-1,2,4-triazol-4-ylamine
209-533-5 584-13-4 Active Intermediate Individual Intermediate use only 31-05-2016 View substance registered dossier
4H-1,3-Dioxino[4,5-c]pyridine-5-carboxaldehyde, 2,2,8-trimethyl-
922-317-1 6560-65-2 Active Intermediate Joint Intermediate use only 24-03-2017 View substance registered dossier
4H-1,3-Dioxino[4,5-c]pyridine-5-methanol, .alpha.-(4-chlorophenyl)-2,2,8-trimethyl-
814-124-5 133545-64-9 Active Intermediate Joint Intermediate use only 10-05-2017 View substance registered dossier
4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester
605-256-2 16150-45-1 Active Intermediate Joint Intermediate use only 04-04-2018 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 09-07-2021 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 25-01-2018 View substance registered dossier
4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1)
601-635-1 119812-29-2 Active Intermediate Individual Intermediate use only 15-02-2013 View substance registered dossier
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester
620-286-6 59469-49-7 Active Intermediate Individual Intermediate use only 10-11-2016 View substance registered dossier
4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro-
917-666-1 61196-37-0 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-acetyl-1,2,3,6,7,11b-hexahydro-
470-180-7 61196-40-5 Active Intermediate Joint Intermediate use only 18-10-2019 View substance registered dossier
4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-aminoethyl)-6,7,8,9-tetrahydro-2-methyl-, hydrochloride (1:2)
700-074-0 1333491-21-6 Active Intermediate Individual Intermediate use only 04-11-2010 View substance registered dossier
4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 5,6-dihydro-6-methyl-4-oxo-
601-694-3 120279-88-1 Active Intermediate Individual Intermediate use only 01-04-2014 View substance registered dossier
4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol
943-142-7 - Active Intermediate Joint Intermediate use only 08-04-2021 View substance registered dossier
5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
629-877-3 376592-57-3 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
5'-chloro-2'-methoxy-[1,1'-biphenyl]-3-carboxylic acid
825-843-9 1170133-64-8 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
5'-chloro-2'-methoxyacetoacetanilide
258-189-2 52793-11-0 Active Intermediate Joint Intermediate use only 14-05-2018 View substance registered dossier
5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide
202-182-9 92-72-8 Active Intermediate Joint Intermediate use only 02-10-2018 View substance registered dossier
5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide
205-207-1 135-63-7 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
212-944-2 885-70-1 Active Intermediate Individual Intermediate use only 05-10-2020 View substance registered dossier
5,5'-((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-2-((S)-pyrrolidin-2-yl)-1H-benzo[d]imidazole)
826-675-9 1332357-14-8 Active Intermediate Joint Intermediate use only 02-06-2020 View substance registered dossier
5,5-dimethylcyclohexane-1,3-dione
204-804-4 126-81-8 Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1) 639-694-0 188416-20-8 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 4-Quinazolinamine, 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitro- 810-185-7 179552-73-9 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)- 620-069-6 945553-94-6 - View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)- 620-069-6 945553-94-6 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)- 620-069-6 945553-94-6 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- 925-395-5 314771-88-5 2021 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 4-Sulfonamidophenylhydrazine hydrochloride 605-823-4 17852-52-7 - View substance registered dossier
NUFARM S.A.S Immeuble West Plaza, 11 rue du Débarcadère 92700 Colombes France France Active 4-tert-butyl-2,6-dinitrochlorobenzene 218-672-0 2213-81-2 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 4-tert-butyl-3-hydroxy-2,6-xylylacetonitrile 259-766-1 55699-10-0 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 4-tert-butylbenzaldehyde 213-367-9 939-97-9 2013 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-tert-butylbenzaldehyde 213-367-9 939-97-9 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2013 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2012 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2015 View substance registered dossier
Only representative (No publishable name) - - Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 4-tert-butylbenzonitrile 224-137-2 4210-32-6 2020 View substance registered dossier
BorsodChem MCHZ Chemická 2039/1 709 00 Ostrava Czech Republic Czech Republic Active 4-tert-butylbenzylamine 254-681-6 39895-55-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active 4-tert-butylcyclohex-1-ene 606-973-3 2228-98-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture 4-tert-butylcyclohexanol 202-676-4 98-52-2 2021 View substance registered dossier
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Active 4-tert-butylcyclohexanol 202-676-4 98-52-2 2019; 2020 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture 4-tert-butylcyclohexanol 202-676-4 98-52-2 2018 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active 4-tert-butylcyclohexanol 202-676-4 98-52-2 - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 4-tert-butyltoluene 202-675-9 98-51-1 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-tert-butyltoluene 202-675-9 98-51-1 2018 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)- 618-303-7 89786-04-9 - View substance registered dossier
IBI - Istituto Biochimico Italiano Giovanni Lorenzini Spa Via Fossignano, 2 04011 Aprilia (LT) Italy Italy Active 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)- 618-303-7 89786-04-9 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, (2S,3S,5R)- 618-304-2 89789-07-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-Thiazoleacetic acid, 2-(formylamino)-α-oxo- 613-733-1 64987-06-0 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-, hydrochloride (1:2) 937-695-3 1185167-55-8 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 4-THIAZOLIDINE CARBOXYLIC ETHYL ESTER HCl 613-908-2 66223-38-9 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd 604-491-8 145767-92-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4-vinylcyclohexene 202-848-9 100-40-3 2016; 2017 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid 926-027-6 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one 828-315-6 1443532-21-5 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 4H-1,2,4-triazol-4-ylamine 209-533-5 584-13-4 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4H-1,3-Dioxino[4,5-c]pyridine-5-carboxaldehyde, 2,2,8-trimethyl- 922-317-1 6560-65-2 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4H-1,3-Dioxino[4,5-c]pyridine-5-methanol, .alpha.-(4-chlorophenyl)-2,2,8-trimethyl- 814-124-5 133545-64-9 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 2016 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester 605-256-2 16150-45-1 2018 View substance registered dossier
LUMINOCHEM Kutató-Fejlesztő Kft. Háros utca 7/a 1222 Budapest Hungary Hungary Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 2010; 2013; 2016 View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany Germany Active 4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1) 601-635-1 119812-29-2 2013 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester 620-286-6 59469-49-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 4H-Pyrazino[2,1-a]isoquinolin-4-one, 1,2,3,6,7,11b-hexahydro- 917-666-1 61196-37-0 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-acetyl-1,2,3,6,7,11b-hexahydro- 470-180-7 61196-40-5 2013; 2019 View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-aminoethyl)-6,7,8,9-tetrahydro-2-methyl-, hydrochloride (1:2) 700-074-0 1333491-21-6 2009; 2010 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 5,6-dihydro-6-methyl-4-oxo- 601-694-3 120279-88-1 2014 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol 943-142-7 - 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid 629-877-3 376592-57-3 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 5'-chloro-2'-methoxy-[1,1'-biphenyl]-3-carboxylic acid 825-843-9 1170133-64-8 - View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 5'-chloro-2'-methoxyacetoacetanilide 258-189-2 52793-11-0 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active 5'-chloro-2'-methoxyacetoacetanilide 258-189-2 52793-11-0 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 5'-chloro-2'-methoxyacetoacetanilide 258-189-2 52793-11-0 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide 202-182-9 92-72-8 2018 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide 205-207-1 135-63-7 - View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide 205-207-1 135-63-7 - View substance registered dossier
KINSY, S.L. Avda. Europa s/n Parque Industrial de Alhama 30840 Alhama de Murcia Murcia Spain Spain Active 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 212-944-2 885-70-1 - View substance registered dossier
[Confidential] - - - 5,5'-((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-2-((S)-pyrrolidin-2-yl)-1H-benzo[d]imidazole) 826-675-9 1332357-14-8 - View substance registered dossier
BENECHIM René Magritte 163 7860 Lessines Belgium Belgium Active 5,5-dimethylcyclohexane-1,3-dione 204-804-4 126-81-8 2012 View substance registered dossier
Chemical Inspection & Regulation Service Limited (Hangzhou Grascent Co., Ltd.) Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 5,5-dimethylcyclohexane-1,3-dione 204-804-4 126-81-8 - View substance registered dossier
Chemische Fabrik Berg GmbH Mainthalstrasse 3 06749 Bitterfeld-Wolfen Germany Germany Active 5,5-dimethylcyclohexane-1,3-dione 204-804-4 126-81-8 2012 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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