Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2,2-dimethyl-1,3-dioxolan-4-yl)methyl methacrylate
230-408-6 7098-80-8 Active Intermediate Individual Intermediate use only 26-03-2018 View substance registered dossier
(2,3-dichlorophenyl)oxoacetonitrile
278-747-9 77668-42-9 Active Intermediate Joint Intermediate use only 18-09-2014 View substance registered dossier
(2,4-Difluorophenyl)(4-Fluorophenyl)methanone
813-638-7 80512-44-3 Active Intermediate Individual Intermediate use only 23-01-2018 View substance registered dossier
(2,5-dichloropentyl)ammonium chloride
263-758-3 62922-45-6 Active Intermediate Joint Intermediate use only 27-07-2018 View substance registered dossier
(2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
433-520-5 82911-69-1 Active Intermediate Joint Intermediate use only 06-03-2020 View substance registered dossier
(2,6-xylyloxy) acetic acid
430-910-7 13335-71-2 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine
955-183-8 - Active Intermediate Joint Intermediate use only 21-12-2021 View substance registered dossier
(2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1)
941-991-8 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(2-bromophenyl)acetonitrile
243-091-4 19472-74-3 Active Intermediate Joint Intermediate use only 24-05-2018 View substance registered dossier
(2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone
BUTAMINONITRODARONE; SR33581
444-800-1 141645-23-0 Active Intermediate Individual Intermediate use only 22-11-2010 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone
217-773-7 1951-26-4 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone
257-959-5 52490-15-0 Active Intermediate Joint Intermediate use only 14-12-2018 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
280-851-4 83790-87-8 Active Intermediate Joint Intermediate use only 27-04-2018 View substance registered dossier
(2-chloro-1,1-dimethylethyl)benzene
208-197-7 515-40-2 Active Intermediate Joint Intermediate use only 02-09-2021 View substance registered dossier
(2-chloropyrid-3-yl)methanol
690-999-5 42330-59-6 Active Intermediate Joint Intermediate use only 20-11-2017 View substance registered dossier
(2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide
250-002-2 30018-16-7 Active Intermediate Joint Intermediate use only 19-03-2018 View substance registered dossier
(2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide
250-002-2 30018-16-7 Active Intermediate Individual Intermediate use only 14-08-2013 View substance registered dossier
(2-hydroxypropyl)trimethylammonium chloride
219-183-5 2382-43-6 Active Intermediate Joint Intermediate use only 20-12-2016 View substance registered dossier
(2-methylpropyl)lithium;isobutyllithium
440-620-2 920-36-5 Active Intermediate Individual Intermediate use only 17-12-2010 View substance registered dossier
(2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate
600-104-1 100499-89-6 Active Intermediate Joint Intermediate use only 15-12-2020 View substance registered dossier
(20R,25R)-spirost-5-en-3β-ol
208-134-3 512-04-9 Active Intermediate Joint Intermediate use only 04-08-2021 View substance registered dossier
(22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid
815-717-1 1169630-40-3 Active Intermediate Individual Intermediate use only 29-05-2019 View substance registered dossier
(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE
610-496-6 500292-86-4 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
(2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid
813-178-7 1489004-27-4 Active Intermediate Joint Intermediate use only 24-06-2020 View substance registered dossier
(2E)-3-Phenylacrylaldehyde
604-377-8 14371-10-9 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
(2E)-4,4,4-trifluorobut-2-en-1-ol
835-846-7 83706-94-9 Active Intermediate Joint Intermediate use only 18-07-2019 View substance registered dossier
(2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine
814-576-3 40267-53-6 Active Intermediate Joint Intermediate use only 23-10-2020 View substance registered dossier
(2E,4E)-2,4-decadienoic acid
250-149-2 30361-33-2 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
(2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1)
619-006-5 942519-41-7 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
(2E,4R)-5-{[1,1’-biphenyl]-4-yl}-4-[(tert-butoxycarbonyl)amino]-2-methylpent-2-enoic acid
695-654-2 1012341-48-8 Active Intermediate Individual Intermediate use only 03-09-2014 View substance registered dossier
(2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
823-704-7 126918-17-0 Active Intermediate Joint Intermediate use only 07-04-2018 View substance registered dossier
(2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
819-998-1 135270-08-5 Active Intermediate Joint Intermediate use only 19-01-2018 View substance registered dossier
(2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol
811-584-9 1294504-67-8 Active Intermediate Joint Intermediate use only 26-11-2021 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - Active Intermediate Individual Intermediate use only 15-01-2020 View substance registered dossier
(2R)-2-aminobutan-1-ol L-tartrate monohydrate
814-787-0 153078-05-8 Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
(2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride
700-669-5 2788-28-5 Active Intermediate Joint Intermediate use only 01-08-2019 View substance registered dossier
(2R)-[(methoxycarbonyl)amino](phenyl)acetic acid
694-843-7 50890-96-5 Active Intermediate Individual Intermediate use only 13-09-2021 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride
867-647-6 1179802-09-5 Active Intermediate Joint Intermediate use only 21-07-2021 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
815-196-0 1175536-50-1 Active Intermediate Joint Intermediate use only 31-08-2017 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
4-AA; AOSA; AZETIDONE-KANEKA; GR91990X
408-050-9 76855-69-1 Active Intermediate Individual Intermediate use only 20-09-2012 View substance registered dossier
(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide
609-299-8 368421-58-3 Active Intermediate Individual Intermediate use only 16-10-2017 View substance registered dossier
(2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid
805-624-4 1367878-84-9 Active Intermediate Joint Intermediate use only 28-05-2020 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride
948-534-1 1639208-51-7 Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
(2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran
857-987-3 64363-77-5 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile
856-564-0 1355357-49-1 Active Intermediate Joint Intermediate use only 09-07-2020 View substance registered dossier
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9h-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate
875-019-8 1294481-82-5 Active Intermediate Joint Intermediate use only 27-10-2021 View substance registered dossier
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
857-885-9 1191237-69-0 Active Intermediate Joint Intermediate use only 07-09-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ERM_GmbH_OR14_GUK Siemenstrasse 9. 63263 Neu Isenburg Hessen Germany Germany Active (2,2-dimethyl-1,3-dioxolan-4-yl)methyl methacrylate 230-408-6 7098-80-8 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (2,3-dichlorophenyl)oxoacetonitrile 278-747-9 77668-42-9 - View substance registered dossier
Stewardship Chemicals 40 Długosza 67 43-188 Orzesze Poland Poland Active (2,4-Difluorophenyl)(4-Fluorophenyl)methanone 813-638-7 80512-44-3 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 2010; 2013; 2020 View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A. Industrial area of Patras, Building block 1 25018 Patras Greece Greece Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2,6-xylyloxy) acetic acid 430-910-7 13335-71-2 2011; 2018 View substance registered dossier
[Confidential] - - - (2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine 955-183-8 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1) 941-991-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone 444-800-1 141645-23-0 2010 View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 2017 View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017; 2018 View substance registered dossier
Asambly Europe Company Limited Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland Ireland Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone 280-851-4 83790-87-8 - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active (2-chloro-1,1-dimethylethyl)benzene 208-197-7 515-40-2 - View substance registered dossier
[Confidential] - - - (2-chloro-1,1-dimethylethyl)benzene 208-197-7 515-40-2 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-chloropyrid-3-yl)methanol 690-999-5 42330-59-6 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide 250-002-2 30018-16-7 - View substance registered dossier
[Confidential] - - - (2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide 250-002-2 30018-16-7 - View substance registered dossier
[Confidential] - - - (2-hydroxypropyl)trimethylammonium chloride 219-183-5 2382-43-6 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active (2-methylpropyl)lithium;isobutyllithium 440-620-2 920-36-5 2010 View substance registered dossier
RANKE QUIMICA S.A. Ctra. Nacional II, Km 593 08740 Sant Andreu de la Barca Barcelona Spain Spain Active (2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate 600-104-1 100499-89-6 2018; 2020 View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany Germany Active (20R,25R)-spirost-5-en-3β-ol 208-134-3 512-04-9 - View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active (20R,25R)-spirost-5-en-3β-ol 208-134-3 512-04-9 - View substance registered dossier
Novo Nordisk A/S Novo Alle 2880 Bagsværd Denmark Denmark Active (22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid 815-717-1 1169630-40-3 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid 813-178-7 1489004-27-4 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (2E)-3-Phenylacrylaldehyde 604-377-8 14371-10-9 - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active (2E)-4,4,4-trifluorobut-2-en-1-ol 835-846-7 83706-94-9 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine 814-576-3 40267-53-6 2020 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E,4E)-2,4-decadienoic acid 250-149-2 30361-33-2 2020 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1) 619-006-5 942519-41-7 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy IE Ringaskiddy Cork Ireland Ireland Active (2E,4R)-5-{[1,1’-biphenyl]-4-yl}-4-[(tert-butoxycarbonyl)amino]-2-methylpent-2-enoic acid 695-654-2 1012341-48-8 2014 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 823-704-7 126918-17-0 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 819-998-1 135270-08-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol 811-584-9 1294504-67-8 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (2R)-2-aminobutan-1-ol L-tartrate monohydrate 814-787-0 153078-05-8 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 - View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 2019 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2R)-[(methoxycarbonyl)amino](phenyl)acetic acid 694-843-7 50890-96-5 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Selectchemie Italia Srl Via Messina, 47 20154 Milano Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate 815-196-0 1175536-50-1 - View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
[Confidential] - - - (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide 609-299-8 368421-58-3 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid 805-624-4 1367878-84-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride 948-534-1 1639208-51-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran 857-987-3 64363-77-5 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile 856-564-0 1355357-49-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9h-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate 875-019-8 1294481-82-5 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile 857-885-9 1191237-69-0 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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