Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Reaction products of 2-hydroxy-6-nitro-4-sulphonaphthalene-1-diazonium coupled with resorcinol, subsequently coupled with diazotised 5-amino-2-anilinobenzenesulphonic acid, iron(III) complexes, sodium salts
947-799-0 - Active Full Joint ≥ 10 to < 100 tonnes 21-12-2020 View substance registered dossier
( 4-hydroxystyrene, 4-t butoxy styrene and 2,5-dimethyl -2.5-diacryloxyhexane) copolymer
433-610-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
((2R, 5S)-5-(4-Amino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic Acid, (2S)-Isopropyl-(5R)-methyl-(1R)-cyclohexyl Ester
939-499-3 - Active Intermediate Joint Intermediate use only 17-01-2022 View substance registered dossier
((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one
953-513-5 - Cease Manufacture Full Joint Cease manufacture 04-08-2021 View substance registered dossier
((6-chloro-4-((2-methoxy-3-(1-methyl-1H-1.2.4-triazol-3-yl)phenyl)amino)pyridazine-3-carbonyl)oxy) hemi-zinc salt
950-319-2 - Active Intermediate Individual Intermediate use only 10-07-2019 View substance registered dossier
(+)-13-ethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
D-ETHYLGONENDION
418-490-3 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol
944-817-9 - Active Full Joint ≥ 10 to < 100 tonnes 01-07-2020 View substance registered dossier
(+-)-(3aRS,5aSR,9aSR,9bSR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan
948-069-4 - Active Full Joint ≥ 1 to < 10 tonnes 11-05-2021 View substance registered dossier
(+-)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2- methyl-4H-pyrido[1,2-a]pyrimidin-4-one
451-680-4 - Active NONS Joint Tonnage data confidential 08-08-2017 View substance registered dossier
(+/-)-1-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-3-ethylthiourea
924-673-3 - Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
(+/-)-2,3-dihydro-2-hydroxy-3,3-dimethylbenzofuran-5-ylethanesulfonate
NC 9770
402-720-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(+/-)-cis-3-acetoxy-4-phenylazetidine-2-one
BMS 183040-01
425-840-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(+/–)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane
419-620-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(-)-(R,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran and (-)-(R,S)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
930-890-4 - Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
(1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium
(1,1'- BIS(DIPHENYLPHOSPHINO)FERROCENE); DICHLOROPALLADIUM
460-040-3 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(1,5 CYCLOOCTADIEN)RUTHENIUM(II) CHLORID POLYMER
442-400-1 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(1,5-cyclooctadiene)(2,4-pentanedionato)rhodium(I)
RHODIUM, (1,5-CYCLOOCTADIENE)(2,4-PENTANEDIONATO)
456-980-9 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(1-3)PEPTIDE
427-530-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1-ethoxyethoxy)cyclododecane
446-240-3 - Active Full Joint ≥ 1 tonnes 03-08-2021 View substance registered dossier
(1-ethoxyethoxy)cyclododecane
446-240-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1-naphthylmethyl)(tetrahydrofuran-2-ylmethyl)malonic acid hydrate (1:1)
700-583-8 - Active Intermediate Joint Intermediate use only 08-05-2017 View substance registered dossier
(17β)-3-oxoestra-4,6-dien-17-yl acetate
425-330-6 - Active NONS Individual Tonnage data confidential 26-01-2011 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene
- - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
(1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
943-551-0 - Active Intermediate Joint Intermediate use only 24-05-2017 View substance registered dossier
(1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 - Active Intermediate Joint Intermediate use only 15-03-2023 View substance registered dossier
(1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane)
443-460-1 - Active Full Joint ≥ 1 tonnes 05-07-2012 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active Intermediate Joint Intermediate use only 13-07-2018 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active NONS Joint Tonnage data confidential 07-10-2010 View substance registered dossier
(1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate
943-085-8 - Cease Manufacture Intermediate Individual Cease manufacture 04-04-2016 View substance registered dossier
(1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione
700-729-0 - Active Intermediate Joint Intermediate use only 08-12-2020 View substance registered dossier
(1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid
944-682-6 - Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one
942-035-2 - Active Intermediate Individual Intermediate use only 04-03-2015 View substance registered dossier
(1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline
445-640-5 - Active NONS Individual Tonnage data confidential 25-05-2011 View substance registered dossier
(1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide
940-296-7 - Active Full Joint ≥ 1 to < 10 tonnes 11-11-2015 View substance registered dossier
(1S)-1-NAPHTHYLETHYLAMINE
436-100-1 - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate
700-779-3 - Cease Manufacture Intermediate Individual Cease manufacture 31-05-2012 View substance registered dossier
(1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane
700-524-6 - Active Intermediate Joint Intermediate use only 13-01-2020 View substance registered dossier
(1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene
700-736-9 - Active Full Individual ≥ 100 to < 1 000 tonnes 07-06-2019 View substance registered dossier
(2,3,5,6-tetrafluoro-4-methylphenyl)methanol
453-520-9 - No longer Valid NONS Individual No longer valid 08-12-2020 View substance registered dossier
(2,4,6-trioxo-2H,4H,6H-1,3,5-triazine-1,3,5-triyl)triethylene tri(acetoacetate)
CD 26-155
403-570-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active Full Joint ≥ 10 to < 100 tonnes 12-12-2022 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2,5-dimethylphenyl)-acetyl chloride
470-780-9 - Active Intermediate Joint Intermediate use only 08-12-2022 View substance registered dossier
(2,5-dimethylphenyl)-acetyl chloride
470-780-9 - Cease Manufacture NONS Individual Cease manufacture 28-03-2018 View substance registered dossier
(2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine
955-183-8 - Active Intermediate Joint Intermediate use only 21-12-2021 View substance registered dossier
(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propyl)hydrazine
449-460-8 - Active NONS Joint Tonnage data confidential 30-01-2023 View substance registered dossier
(2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1)
941-991-8 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(2-(methylamino)pyridin-3-yl)methyl 2-(tert-butoxycarbonyl(methyl)amino)acetate
928-404-0 - Active Intermediate Individual Intermediate use only 12-06-2018 View substance registered dossier
(2-benzyl-acryloylamino)-acetic acid benzyl ester
921-619-0 - Active Intermediate Joint Intermediate use only 23-09-2021 View substance registered dossier
(2-butoxyethoxy)acetic acid
451-650-0 - Active NONS Individual Tonnage data confidential 10-12-2010 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - Active Intermediate Joint Intermediate use only 22-11-2010 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - No longer Valid Intermediate Individual No longer valid 17-12-2010 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - Active NONS Individual Tonnage data confidential 09-12-2013 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - Active Intermediate Individual Intermediate use only 28-11-2011 View substance registered dossier
(2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide
939-152-6 - Active Intermediate Joint Intermediate use only 27-09-2022 View substance registered dossier
(2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal
919-772-3 - Active Intermediate Individual Intermediate use only 11-12-2015 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - Active Intermediate Individual Intermediate use only 15-01-2020 View substance registered dossier
(2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt
944-007-5 - Active Intermediate Joint Intermediate use only 13-12-2016 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate
UK-103,449-BV
427-100-0 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1)
920-610-9 - Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
927-721-1 - Active Intermediate Joint Intermediate use only 19-06-2020 View substance registered dossier
(2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride
928-729-8 - Active Intermediate Joint Intermediate use only 24-04-2013 View substance registered dossier
(2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate
917-473-2 - Active Intermediate Joint Intermediate use only 16-04-2013 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 to < 100 tonnes 16-05-2017 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 tonnes 15-02-2012 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Intermediate Joint Intermediate use only 19-12-2016 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Joint Intermediate use only 26-02-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Joint Intermediate use only 28-01-2019 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid
954-943-6 - Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone
477-290-4 - Active NONS Joint Tonnage data confidential 01-03-2013 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active Full Joint ≥ 1 to < 10 tonnes 15-11-2022 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid
949-609-1 - Active Intermediate Joint Intermediate use only 29-04-2022 View substance registered dossier
(2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran
941-817-0 - Active Intermediate Individual Intermediate use only 10-02-2015 View substance registered dossier
(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1)
947-432-4 - Active Intermediate Joint Intermediate use only 04-09-2020 View substance registered dossier
(2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2)
954-871-5 - Active Intermediate Individual Intermediate use only 19-08-2021 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - No longer Valid Intermediate Individual No longer valid 19-10-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Individual Cease manufacture 05-11-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - No longer Valid Intermediate Joint No longer valid 04-09-2012 View substance registered dossier
(2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate
942-044-1 - Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate
938-481-2 - Active Intermediate Joint Intermediate use only 31-10-2018 View substance registered dossier
(2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester
411-020-8 - Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid
944-347-4 - Active Intermediate Joint Intermediate use only 13-03-2017 View substance registered dossier
(2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid
444-810-6 - Active Full Joint ≥ 10 to < 100 tonnes 11-05-2021 View substance registered dossier
(3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane)
951-684-0 - Active Intermediate Joint Intermediate use only 26-02-2021 View substance registered dossier
(3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane)
LC-OLIGOMER
454-660-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3-(Formylamino)propyl)dimethylammonioacetate
480-680-7 - Active Full Joint ≥ 100 to < 1 000 tonnes 22-10-2020 View substance registered dossier
(3-Chloro-4-fluoro-phenyl)-{6-nitro-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-4-yl}-amine
925-395-5 - Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
(3-chloropyridin-2-yl)hydrazine
474-260-2 - Active Intermediate Joint Intermediate use only 24-09-2020 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Zaitex SpA Via artigianato 15 Povolaro 36030 Dueville Vi Italy Italy Active Reaction products of 2-hydroxy-6-nitro-4-sulphonaphthalene-1-diazonium coupled with resorcinol, subsequently coupled with diazotised 5-amino-2-anilinobenzenesulphonic acid, iron(III) complexes, sodium salts 947-799-0 - - View substance registered dossier
EUROCOLOR SCARL VIA EMILIA PONENTE, 593 48014 CASTEL BOLOGNESE Italy Italy Active Reaction products of 2-hydroxy-6-nitro-4-sulphonaphthalene-1-diazonium coupled with resorcinol, subsequently coupled with diazotised 5-amino-2-anilinobenzenesulphonic acid, iron(III) complexes, sodium salts 947-799-0 - - View substance registered dossier
- - - - ( 4-hydroxystyrene, 4-t butoxy styrene and 2,5-dimethyl -2.5-diacryloxyhexane) copolymer 433-610-4 - - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active ((2R, 5S)-5-(4-Amino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic Acid, (2S)-Isopropyl-(5R)-methyl-(1R)-cyclohexyl Ester 939-499-3 - 2022 View substance registered dossier
Yordas GmbH Äuβere Nürnberger Straβe 62 91301 Forchheim Germany Germany Cease Manufacture ((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one 953-513-5 - 2023 View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active ((6-chloro-4-((2-methoxy-3-(1-methyl-1H-1.2.4-triazol-3-yl)phenyl)amino)pyridazine-3-carbonyl)oxy) hemi-zinc salt 950-319-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (+)-13-ethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione 418-490-3 - 2022 View substance registered dossier
[Confidential] - - - (+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol 944-817-9 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol 944-817-9 - 2018; 2020 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (+-)-(3aRS,5aSR,9aSR,9bSR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan 948-069-4 - 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (+-)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2- methyl-4H-pyrido[1,2-a]pyrimidin-4-one 451-680-4 - 2010; 2013; 2017 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (+/-)-1-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-3-ethylthiourea 924-673-3 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (+/-)-2,3-dihydro-2-hydroxy-3,3-dimethylbenzofuran-5-ylethanesulfonate 402-720-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (+/-)-cis-3-acetoxy-4-phenylazetidine-2-one 425-840-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (+/–)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane 419-620-1 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (+/–)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane 419-620-1 - 2017 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (-)-(R,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran and (-)-(R,S)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran 930-890-4 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium 460-040-3 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (1,5 CYCLOOCTADIEN)RUTHENIUM(II) CHLORID POLYMER 442-400-1 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (1,5-cyclooctadiene)(2,4-pentanedionato)rhodium(I) 456-980-9 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (1-3)PEPTIDE 427-530-9 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1-ethoxyethoxy)cyclododecane 446-240-3 - 2011; 2012; 2021 View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1-ethoxyethoxy)cyclododecane 446-240-3 - 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1-ethoxyethoxy)cyclododecane 446-240-3 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (1-naphthylmethyl)(tetrahydrofuran-2-ylmethyl)malonic acid hydrate (1:1) 700-583-8 - 2017 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (17β)-3-oxoestra-4,6-dien-17-yl acetate 425-330-6 - 2011 View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene - - - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol - - - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 943-551-0 - - View substance registered dossier
[Confidential] - - - (1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate - - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011; 2019; 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011; 2023 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2018 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
- - - - (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate 943-085-8 - 2021 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2021 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2019 View substance registered dossier
[Confidential] - - - (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid 944-682-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one 942-035-2 - - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline 445-640-5 - 2011 View substance registered dossier
[Confidential] - - - (1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide 940-296-7 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1S)-1-NAPHTHYLETHYLAMINE 436-100-1 - 2017 View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate 700-779-3 - 2020 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane 700-524-6 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane 700-524-6 - 2017 View substance registered dossier
Labcorp Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain Spain Active (1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene 700-736-9 - 2019 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (2,3,5,6-tetrafluoro-4-methylphenyl)methanol 453-520-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2,4,6-trioxo-2H,4H,6H-1,3,5-triazine-1,3,5-triyl)triethylene tri(acetoacetate) 403-570-2 - - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2021 View substance registered dossier
FIRMENICH GRASSE SAS OR 4 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2011; 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (2,5-dimethylphenyl)-acetyl chloride 470-780-9 - 2010; 2022 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture (2,5-dimethylphenyl)-acetyl chloride 470-780-9 - 2019 View substance registered dossier
[Confidential] - - - (2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine 955-183-8 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propyl)hydrazine 449-460-8 - 2011; 2023 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1) 941-991-8 - - View substance registered dossier
[Confidential] - - - (2-(methylamino)pyridin-3-yl)methyl 2-(tert-butoxycarbonyl(methyl)amino)acetate 928-404-0 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2-benzyl-acryloylamino)-acetic acid benzyl ester 921-619-0 - 2021 View substance registered dossier
Kao Chemicals GmbH Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany Germany Active (2-butoxyethoxy)acetic acid 451-650-0 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2010 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2019 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2021 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - 2013 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide 939-152-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal 919-772-3 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active (2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt 944-007-5 - - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Pfizer Ltd Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom United Kingdom No longer Valid (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate 427-100-0 - 2021 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1) 920-610-9 - 2021; 2022 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - 2013 View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride 928-729-8 - 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate 917-473-2 - 2011; 2013 View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2009; 2010; 2017 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2012 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
MAPIC Europe NV EXCELSIORLAAN 83 1930 ZAVENTEM Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
B.I.G. - OR634 Technische Schoolstraat 43A 2440 Geel Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2011; 2012; 2014; 2020 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2014 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2018 View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2012 View substance registered dossier
[Confidential] - - - (2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid 954-943-6 - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - 2019 View substance registered dossier
Gruenenthal GmbH Zieglerstrasse 6 52078 Aachen Germany Germany Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - 2022 View substance registered dossier
- - - - (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - - View substance registered dossier
[Confidential] - - - (2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran 941-817-0 - - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) 947-432-4 - 2018; 2020 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2) 954-871-5 - - View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate 942-044-1 - 2017 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate 938-481-2 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid 944-347-4 - - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - 2014; 2021 View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - - View substance registered dossier
[Confidential] - - - (3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane) 951-684-0 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane) 454-660-3 - - View substance registered dossier
[Confidential] - - - (3-(Formylamino)propyl)dimethylammonioacetate 480-680-7 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (3-Chloro-4-fluoro-phenyl)-{6-nitro-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-4-yl}-amine 925-395-5 - 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Cease Manufacture (3-chloropyridin-2-yl)hydrazine 474-260-2 - 2023 View substance registered dossier
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark Active (3-chloropyridin-2-yl)hydrazine 474-260-2 - - View substance registered dossier
[Confidential] - - - (3-chloropyridin-2-yl)hydrazine 474-260-2 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.