Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 06 August 2021. Database contains 23376 unique substances and contains information from 104385 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
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  • Uses at industrial sites
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Details
''amyl nitrite'', mixed isomers 203-770-8 463-04-7 Active Full Joint ≥ 10 to < 100 tonnes 28-06-2019 View substance registered dossier
''amyl nitrite'', mixed isomers 203-770-8 463-04-7 Active Intermediate Joint Intermediate use only 10-12-2019 View substance registered dossier
(+)-(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-3-spiro-1'-(cyclohex-2'-en-4'-one)
430-460-1 133636-82-5 Active NONS Joint Tonnage data confidential 22-11-2012 View substance registered dossier
(+)-14-diethoxycarbonyl-1α-ethyl-1,2,3,4,5,6,12,12b-octahydro-indolo-[2,3-a]-tetrahydro-pyranyl-[2,3-c]-quinolizine
692-750-6 300661-83-0 Active Intermediate Joint Intermediate use only 27-04-2020 View substance registered dossier
(+)-2-amino-1-butanol
227-475-9 5856-62-2 Active Intermediate Joint Intermediate use only 10-04-2017 View substance registered dossier
(+)-bornan-2-one
207-355-2 464-49-3 Active Full Joint ≥ 100 to < 1 000 tonnes 16-03-2020 View substance registered dossier
(+)-L-arginine hydrochloride
214-275-1 1119-34-2 Active Full Joint ≥ 100 to < 1 000 tonnes 01-07-2021 View substance registered dossier
(+)-L-arginine hydrochloride
214-275-1 1119-34-2 Active Intermediate Joint Intermediate use only 30-04-2018 View substance registered dossier
(+)-menthol
239-387-8 15356-60-2 Active Full Joint ≥ 1 to < 10 tonnes 13-10-2010 View substance registered dossier
(+)-neomenthol
218-691-4 2216-52-6 Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PARCEL WORLD DISTRIBUTION 9 rue de la chapelles 8017 strassen Luxembourg Luxembourg Active ''amyl nitrite'', mixed isomers 203-770-8 463-04-7 2019 View substance registered dossier
BENECHIM René Magritte 163 7860 Lessines Belgium Belgium Active ''amyl nitrite'', mixed isomers 203-770-8 463-04-7 - View substance registered dossier
BELGO-PRISM 14 chemin du fundus 7822 Ghislenghien Belgium Belgium Active ''amyl nitrite'', mixed isomers 203-770-8 463-04-7 - View substance registered dossier
Chemservice S.A. (V3S9) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active ''amyl nitrite'', mixed isomers 203-770-8 463-04-7 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (+)-(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-3-spiro-1'-(cyclohex-2'-en-4'-one) 430-460-1 133636-82-5 2011; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (+)-(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-3-spiro-1'-(cyclohex-2'-en-4'-one) 430-460-1 133636-82-5 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (+)-14-diethoxycarbonyl-1α-ethyl-1,2,3,4,5,6,12,12b-octahydro-indolo-[2,3-a]-tetrahydro-pyranyl-[2,3-c]-quinolizine 692-750-6 300661-83-0 2020 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active (+)-2-amino-1-butanol 227-475-9 5856-62-2 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (+)-bornan-2-one 207-355-2 464-49-3 2018; 2020 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (+)-bornan-2-one 207-355-2 464-49-3 - View substance registered dossier
Frey + Lau GmbH Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany Germany Active (+)-bornan-2-one 207-355-2 464-49-3 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (+)-bornan-2-one 207-355-2 464-49-3 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2020 View substance registered dossier
Life Technologies Europe BV Kwartsweg 2 2665 NN Bleiswijk Netherlands Netherlands Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
Kyowa Hakko Europe GmbH Am Wehrhahn 50 40211 Düsseldorf Germany Germany Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2017 View substance registered dossier
SAFC Biosciences Limited Smeaton Road, West Potway SP10 3LF Andover United Kingdom United Kingdom No longer Valid (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2021 View substance registered dossier
Daesang Europe B.V. Van Heuven Goedhartlaan 935 1181 Amstelveen Netherlands Netherlands Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
Ajinomoto OmniChem (OR) Cooppallaan 91 9230 Wetteren Belgium Belgium Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2021 View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2021 View substance registered dossier
Merck Life Science A/S Vandtårnsvej 62A 2860 Søborg Denmark Denmark Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
Global Life Sciences Solutions Austria GmbH & Co KG Kremplstraße 5 4061 Pasching Austria Austria Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
AVANTOR PERFORMANCE MATERIALS POLAND SPÓŁKA AKCYJNA Sowińskiego 11 44-101 Gliwice Silesia Poland Poland Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 2020 View substance registered dossier
Laboratorios Miret, S.A. Geminis 4 08228 Terrassa Barcelona Spain Spain Active (+)-L-arginine hydrochloride 214-275-1 1119-34-2 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (+)-menthol 239-387-8 15356-60-2 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active (+)-neomenthol 218-691-4 2216-52-6 - View substance registered dossier

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