Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 06 August 2021. Database contains 23376 unique substances and contains information from 104385 dossiers.
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Details
1-isocyanatooctadecane 1-isocyanatohexadecane
907-349-6 - Active Intermediate Joint Intermediate use only 27-02-2020 View substance registered dossier
1-isopropyl-1H-pyrazole
823-314-7 18952-87-9 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
1-isopropyl-4-methyl-bicyclo[3.1.0]hex-2-en-4-ol
944-023-2 - Active Intermediate Joint Intermediate use only 17-02-2017 View substance registered dossier
1-methoxy-2-nitro-4-phenylbenzene
605-152-7 15854-73-6 Active Intermediate Joint Intermediate use only 19-12-2012 View substance registered dossier
1-methoxy-2-propanamine
609-333-1 37143-54-7 Active Intermediate Individual Intermediate use only 28-10-2020 View substance registered dossier
1-methoxycyclododecene
917-624-2 - Active Intermediate Joint Intermediate use only 29-04-2020 View substance registered dossier
1-Methyl piperidine-4-carboxylic acid diethylamide Hydrochloride hydrate
947-089-0 - Active Intermediate Joint Intermediate use only 19-03-2018 View substance registered dossier
1-Methyl piperidine-4-carboxylic acid hydrochloride
815-057-4 71985-80-3 Active Intermediate Joint Intermediate use only 04-07-2017 View substance registered dossier
1-Methyl-1-propylpyrrolidinium bromide
801-424-6 608140-09-6 Active Intermediate Individual Intermediate use only 03-12-2020 View substance registered dossier
1-methyl-2-pyrrolidone
212-828-1 872-50-4 Active Intermediate Joint Intermediate use only 12-11-2020 View substance registered dossier
1-methyl-3-((methyl-λ2-azanyl)methyl)-1H-pyrazole-5-carbonitrile hydrochloride
943-430-2 1643141-20-1 Active Intermediate Joint Intermediate use only 10-09-2019 View substance registered dossier
1-Methyl-3-nitro-guanidine
433-400-2 - Active Intermediate Joint Intermediate use only 07-09-2009 View substance registered dossier
1-methyl-3-phenylpropylamine
244-942-2 22374-89-6 Active Intermediate Joint Intermediate use only 17-04-2018 View substance registered dossier
1-methyl-4-piperidone
215-895-5 1445-73-4 Active Intermediate Joint Intermediate use only 29-10-2020 View substance registered dossier
1-methyl-4-piperidyl diphenylglycolate
222-774-0 3608-67-1 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
1-methylcyclohexane-1-carboxylic acid
214-371-3 1123-25-7 Active Intermediate Joint Intermediate use only 27-02-2013 View substance registered dossier
1-methylcyclohexanecarbonyl chloride
608-291-1 2890-61-1 Active Intermediate Individual Intermediate use only 20-04-2012 View substance registered dossier
1-methylhexyl chloroacetate
700-306-0 383412-05-3 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
1-methylpiperazine
203-639-5 109-01-3 Active Intermediate Joint Intermediate use only 19-12-2019 View substance registered dossier
1-methylpiperidin-4-ol
203-406-8 106-52-5 Active Intermediate Joint Intermediate use only 09-02-2018 View substance registered dossier
1-methylpyrrolidin-3-ol
236-189-3 13220-33-2 Active Intermediate Joint Intermediate use only 18-07-2018 View substance registered dossier
1-Naphthalenamine, 1,2,3,4-tetrahydro-, (1R)-
628-771-4 23357-46-2 Active Intermediate Joint Intermediate use only 06-11-2012 View substance registered dossier
1-Naphthalenamine, 1,2,3,4-tetrahydro-, (1S)-
629-348-7 23357-52-0 Active Intermediate Joint Intermediate use only 06-11-2012 View substance registered dossier
1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride (1:1), (1R,4R)-rel-
616-707-8 79617-89-3 Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
1-Naphthaleneethanamine, 7-methoxy-, hydrochloride (1:1)
604-144-0 139525-77-2 Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,d-dihydroxy-2,6-dimethyl-, monoammonium salt,(bR,dR,1S,2S,6R,8S,8aR)- (9CI);
604-165-5 139893-43-9 Active Intermediate Joint Intermediate use only 07-08-2013 View substance registered dossier
1-Naphthalenemethanamine, a-methyl-
610-076-2 42882-31-5 Active Intermediate Joint Intermediate use only 10-01-2018 View substance registered dossier
1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)
616-640-4 78628-80-5 Active Intermediate Joint Intermediate use only 13-08-2014 View substance registered dossier
1-Naphthalenemethanamine, N-methyl-, hydrochloride (1:1)
613-801-0 65473-13-4 Active Intermediate Joint Intermediate use only 29-03-2017 View substance registered dossier
1-naphthyl isocyanate
201-703-7 86-84-0 Active Intermediate Joint Intermediate use only 19-04-2013 View substance registered dossier
1-naphthylacetonitrile
205-078-1 132-75-2 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1-naphthylamine
205-138-7 134-32-7 Active Intermediate Joint Intermediate use only 25-02-2021 View substance registered dossier
1-nitro-2-phenylsulfanylbenzene
609-953-2 4171-83-9 Active Intermediate Joint Intermediate use only 20-02-2020 View substance registered dossier
1-O-tert-butyl 2-O-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
600-890-6 108963-96-8 Active Intermediate Joint Intermediate use only 30-01-2018 View substance registered dossier
1-Octanesulfonamide, N-[3-(dimethylamino)propyl]-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-
608-993-8 34455-22-6 Active Intermediate Joint Intermediate use only 15-05-2013 View substance registered dossier
1-oxa-4-azaspiro[4.5]decan-4-ethanol
219-101-8 2359-11-7 Active Intermediate Joint Intermediate use only 23-04-2019 View substance registered dossier
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
617-500-5 83905-01-5 Active Intermediate Individual Intermediate use only 30-05-2014 View substance registered dossier
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
616-385-9 76801-85-9 Active Intermediate Individual Intermediate use only 04-12-2014 View substance registered dossier
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
616-385-9 76801-85-9 Active Intermediate Joint Intermediate use only 29-03-2019 View substance registered dossier
1-Pentanone, 1-[4-(4-propylcyclohexyl)phenyl]-, trans-
689-247-9 95149-35-2 Active Intermediate Individual Intermediate use only 20-08-2019 View substance registered dossier
1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, O-(2-aminoethyl)oxime, (1E)-
611-193-1 54739-18-3 Active Intermediate Joint Intermediate use only 19-05-2017 View substance registered dossier
1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, oxime
612-371-1 61747-22-6 Active Intermediate Joint Intermediate use only 24-05-2018 View substance registered dossier
1-Pentene, chlorinated, epoxidized, distn. residues
304-798-4 94279-53-5 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride (1:1)
606-318-1 19478-81-0 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one
922-915-2 - Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
1-phenyl-3-piperidin-1-ylpropan-1-one
635-445-5 73-63-2 Active Intermediate Joint Intermediate use only 01-08-2017 View substance registered dossier
1-phenyl-3H-indol-2-one
441-020-3 - Active Intermediate Joint Intermediate use only 10-02-2020 View substance registered dossier
1-phenylethanol
202-707-1 98-85-1 Active Intermediate Individual Intermediate use only 11-12-2012 View substance registered dossier
1-phenylethanol
202-707-1 98-85-1 Active Intermediate Joint Intermediate use only 26-10-2020 View substance registered dossier
1-phenylethyl hydroperoxide
221-341-3 3071-32-7 Active Intermediate Individual Intermediate use only 11-12-2012 View substance registered dossier
1-phenylpropan-1-ol
202-256-0 93-54-9 Active Intermediate Joint Intermediate use only 19-02-2019 View substance registered dossier
1-phenyltetrazole-5-thiol
201-710-5 86-93-1 Active Intermediate Joint Intermediate use only 24-01-2018 View substance registered dossier
1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester
695-268-4 571188-59-5 Active Intermediate Individual Intermediate use only 16-07-2013 View substance registered dossier
1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester
695-268-4 571188-59-5 Active Intermediate Joint Intermediate use only 19-10-2017 View substance registered dossier
1-Piperazinecarboxylic acid, 4-[(2-fluoro-3-nitrophenyl)methyl]-,methyl ester, hydrochloride (1:1)
843-886-1 1628206-32-5 Active Intermediate Joint Intermediate use only 06-09-2019 View substance registered dossier
1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-, hydrochloride (1:2)
605-374-4 164726-80-1 Active Intermediate Joint Intermediate use only 15-01-2018 View substance registered dossier
1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester
935-907-9 79794-75-5 Active Intermediate Joint Intermediate use only 27-04-2018 View substance registered dossier
1-Piperidinecarboxylic acid, 4-(methylamino)-, ethyl ester
616-013-5 73733-69-4 Active Intermediate Joint Intermediate use only 13-03-2018 View substance registered dossier
1-Propanamine, 3-(methoxydimethylsilyl)-
608-570-8 31024-26-7 Active Intermediate Joint Intermediate use only 04-02-2019 View substance registered dossier
1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-
806-749-7 918504-27-5 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-
806-798-4 1262985-23-8 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-
806-756-5 1262985-24-9 Active Intermediate Joint Intermediate use only 15-06-2021 View substance registered dossier
1-Propanol, 3-(dimethylamino)-, hydrochloride (1:1)
601-495-1 117829-74-0 Active Intermediate Individual Intermediate use only 02-08-2011 View substance registered dossier
1-Propanone, 1-[2-(2-propen-1-yloxy)phenyl]-
604-312-3 142819-94-1 Active Intermediate Individual Intermediate use only 21-09-2015 View substance registered dossier
1-Propanone, 1-phenyl-3-(1-pyrrolidinyl)-
619-034-8 94-39-3 Active Intermediate Individual Intermediate use only 04-05-2018 View substance registered dossier
1-Propanone, 2-methyl-1-[4-(methylthio)phenyl]-
610-979-1 53207-58-2 Active Intermediate Individual Intermediate use only 26-05-2010 View substance registered dossier
1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1)
609-494-8 37951-53-4 Active Intermediate Joint Intermediate use only 31-08-2018 View substance registered dossier
1-Propen-1,2,3-tricarbonsäure tris(2-(2,2,3,3,3,4,4,4-heptafluorbutoxy)-1-(methyl)-ethyl)ester
- - Active Intermediate Joint Intermediate use only 09-06-2021 View substance registered dossier
1-Propene, 2-methyl-, chlorinated, epoxidized, distn. residues
304-801-9 94279-55-7 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
1-Propene, chlorinated, epoxidized, distn. residues
304-800-3 94279-54-6 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
1-Propene, hydroformylation products, high-boiling
A complex combination of products produced by the distillation of products from the hydrogenation of butanal from the hydroformylation of propene. It consists predominantly of organic compounds such as aldehydes, alcohols, esters, ethers and carboxylic acids having carbon numbers in the range of C4-C32 and boiling in the range of approximately 143°C to 282°C (289°F to 540°F).
271-363-2 68551-11-1 Active Intermediate Individual Intermediate use only 19-10-2010 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)-
807-100-0 1378391-45-7 Active Intermediate Individual Intermediate use only 28-09-2016 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 3-[2-[(ethoxycarbonyl)[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-, phenylmethyl ester, (3R,4S)-
944-343-2 2050038-81-6 Active Intermediate Joint Intermediate use only 24-02-2021 View substance registered dossier
1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)-
604-254-9 141818-73-7 Active Intermediate Joint Intermediate use only 06-07-2021 View substance registered dossier
1-tert-butoxycarbonylpiperidine-4-carboxylic acid
700-076-1 84358-13-4 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
1-tert-butyl 2,4-dimethyl (2S,4S)-pyrrolidine-1,2,4-tricarboxylate
807-497-0 1378388-30-7 Active Intermediate Individual Intermediate use only 14-04-2016 View substance registered dossier
1-tert-butyl 2-methyl (2S,4R)-4-{[(4-methylphenyl)sulfonyl]oxy}pyrrolidine-1,2-dicarboxylate
686-032-1 88043-21-4 Active Intermediate Individual Intermediate use only 07-06-2016 View substance registered dossier
1-tert-butyl 2-methyl (2S,4S)-4-(hydroxymethyl)pyrrolidine-1,2-dicarboxylate
807-618-7 1194059-42-1 Active Intermediate Individual Intermediate use only 20-04-2016 View substance registered dossier
1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium iodide hydrate (1:1:1)
606-216-7 190651-18-4 Active Intermediate Joint Intermediate use only 07-10-2019 View substance registered dossier
1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1)
615-984-2 73547-70-3 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
1-{[2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole monomethanesulfonate
617-843-0 86386-77-8 Active Intermediate Individual Intermediate use only 20-01-2011 View substance registered dossier
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride
941-920-0 1628047-87-9 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
1-β-D-arabinofuranosylcytosine hydrochloride
200-713-9 69-74-9 Active Intermediate Joint Intermediate use only 12-12-2017 View substance registered dossier
10,10-dimethylanthracen-9(10H)-one
226-666-4 5447-86-9 Active Intermediate Joint Intermediate use only 03-07-2020 View substance registered dossier
10,11-dihydro-5H-dibenz[b,f]azepine
207-787-1 494-19-9 Active Intermediate Individual Intermediate use only 29-07-2010 View substance registered dossier
10,11-dihydro-5H-dibenz[b,f]azepine
207-787-1 494-19-9 Active Intermediate Joint Intermediate use only 31-01-2020 View substance registered dossier
10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine
201-578-9 84-97-9 Active Intermediate Individual Intermediate use only 23-05-2018 View substance registered dossier
10-[4-(2-chloroethyl)piperazin-1-yl]-2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
609-095-9 352232-17-8 Active Intermediate Joint Intermediate use only 28-03-2018 View substance registered dossier
10-hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl) decan-1-one
700-045-2 104966-97-4 Active Intermediate Individual Intermediate use only 15-04-2011 View substance registered dossier
10-methoxy-1,6-dimethylergoline-8β-methanol
252-405-9 35155-28-3 Active Intermediate Joint Intermediate use only 12-12-2017 View substance registered dossier
10-methoxy-5H-dibenz[b,f]azepine
225-172-6 4698-11-7 Active Intermediate Joint Intermediate use only 03-07-2019 View substance registered dossier
10-Undecenamide, N-[3-(dimethylamino)propyl]-
613-971-6 66654-01-1 Active Intermediate Joint Intermediate use only 24-09-2015 View substance registered dossier
10H-pyrido[3,2-b](1,4)benzothiazine
205-973-7 261-96-1 Active Intermediate Joint Intermediate use only 22-01-2018 View substance registered dossier
11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
249-227-9 28797-48-0 Active Intermediate Joint Intermediate use only 09-04-2018 View substance registered dossier
11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol
224-821-0 4504-88-5 Active Intermediate Joint Intermediate use only 08-03-2018 View substance registered dossier
11-[3-(dimethylamino)propyl]-6H-benzo[c][1]benzothiepin-11-ol
604-888-6 1531-85-7 Active Intermediate Joint Intermediate use only 01-02-2018 View substance registered dossier
11-bromoundecanoic acid
220-602-9 2834-05-1 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
11-bromoundecanol
216-554-3 1611-56-9 Active Intermediate Joint Intermediate use only 03-09-2018 View substance registered dossier
11-piperazin-1-yldibenzo[b,f][1,4]thiazepine dihydrochloride
700-276-9 111974-74-4 Active Intermediate Individual Intermediate use only 07-04-2010 View substance registered dossier
11-piperazin-1-yldibenzo[b,f][1,4]thiazepine dihydrochloride
700-276-9 111974-74-4 Active Intermediate Joint Intermediate use only 27-10-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 1-isocyanatooctadecane 1-isocyanatohexadecane 907-349-6 - - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 1-isocyanatooctadecane 1-isocyanatohexadecane 907-349-6 - - View substance registered dossier
LANXESS Distribution GmbH Chempark 51369 Leverkusen NRW Germany Germany Active 1-isocyanatooctadecane 1-isocyanatohexadecane 907-349-6 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 1-isopropyl-1H-pyrazole 823-314-7 18952-87-9 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 1-isopropyl-4-methyl-bicyclo[3.1.0]hex-2-en-4-ol 944-023-2 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1-methoxy-2-nitro-4-phenylbenzene 605-152-7 15854-73-6 - View substance registered dossier
[Confidential] - - - 1-methoxy-2-propanamine 609-333-1 37143-54-7 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 1-methoxycyclododecene 917-624-2 - 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 1-Methyl piperidine-4-carboxylic acid diethylamide Hydrochloride hydrate 947-089-0 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 1-Methyl piperidine-4-carboxylic acid hydrochloride 815-057-4 71985-80-3 - View substance registered dossier
SOLVIONIC 11 Chemin des Silos 31100 Toulouse France France Active 1-Methyl-1-propylpyrrolidinium bromide 801-424-6 608140-09-6 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 1-methyl-2-pyrrolidone 212-828-1 872-50-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 1-methyl-3-((methyl-λ2-azanyl)methyl)-1H-pyrazole-5-carbonitrile hydrochloride 943-430-2 1643141-20-1 2019 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 1-Methyl-3-nitro-guanidine 433-400-2 - 2009 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture 1-Methyl-3-nitro-guanidine 433-400-2 - 2021 View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active 1-methyl-3-phenylpropylamine 244-942-2 22374-89-6 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 1-methyl-3-phenylpropylamine 244-942-2 22374-89-6 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
Organike S.R.L. Via Matteotti, 19 20852 Villasanta (MB) Italy Italy Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 1-methyl-4-piperidone 215-895-5 1445-73-4 - View substance registered dossier
Laborchemie Apolda GmbH Utenbacher Straße 72-74 99510 Apolda Germany Germany Active 1-methyl-4-piperidyl diphenylglycolate 222-774-0 3608-67-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1-methylcyclohexane-1-carboxylic acid 214-371-3 1123-25-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1-methylcyclohexanecarbonyl chloride 608-291-1 2890-61-1 - View substance registered dossier
[Confidential] - - - 1-methylhexyl chloroacetate 700-306-0 383412-05-3 - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Chemsafe Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Chr. Olesen ChemPharm GmbH Gustav-Becker-Strasse 20B 21218 Seevetal Germany Germany Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1-methylpiperazine 203-639-5 109-01-3 2016; 2017 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 1-methylpiperazine 203-639-5 109-01-3 2017 View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Summit Pharmaceuticals Europe S.r.l. Viale Piero e Alberto Pirelli, 6 20126 Milano Italy Italy Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-methylpiperazine 203-639-5 109-01-3 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active 1-methylpiperazine 203-639-5 109-01-3 2019 View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active 1-methylpiperidin-4-ol 203-406-8 106-52-5 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active 1-methylpyrrolidin-3-ol 236-189-3 13220-33-2 2018 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active 1-methylpyrrolidin-3-ol 236-189-3 13220-33-2 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Naphthalenamine, 1,2,3,4-tetrahydro-, (1R)- 628-771-4 23357-46-2 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Naphthalenamine, 1,2,3,4-tetrahydro-, (1S)- 629-348-7 23357-52-0 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride (1:1), (1R,4R)-rel- 616-707-8 79617-89-3 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride (1:1), (1R,4R)-rel- 616-707-8 79617-89-3 - View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active 1-Naphthaleneethanamine, 7-methoxy-, hydrochloride (1:1) 604-144-0 139525-77-2 - View substance registered dossier
Teva Pharmaceutical Works Private Limited Company Pallagi str. 13 H-4042 Debrecen Hungary Hungary Active 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,d-dihydroxy-2,6-dimethyl-, monoammonium salt,(bR,dR,1S,2S,6R,8S,8aR)- (9CI); 604-165-5 139893-43-9 2013 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active 1-Naphthalenemethanamine, a-methyl- 610-076-2 42882-31-5 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1) 616-640-4 78628-80-5 2014 View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active 1-Naphthalenemethanamine, N-methyl-, hydrochloride (1:1) 613-801-0 65473-13-4 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 1-Naphthalenemethanamine, N-methyl-, hydrochloride (1:1) 613-801-0 65473-13-4 2017 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1-naphthyl isocyanate 201-703-7 86-84-0 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1-naphthyl isocyanate 201-703-7 86-84-0 - View substance registered dossier
LOBA Feinchemie GmbH Fehrgasse 7 2401 Fischamend Austria Austria Active 1-naphthylacetonitrile 205-078-1 132-75-2 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 1-naphthylamine 205-138-7 134-32-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1-naphthylamine 205-138-7 134-32-7 2017 View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active 1-nitro-2-phenylsulfanylbenzene 609-953-2 4171-83-9 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1-O-tert-butyl 2-O-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate 600-890-6 108963-96-8 - View substance registered dossier
Chemours France S.A.S. Rue Frederic Kuhlmann 60870 Villers-Saint-Paul France France Active 1-Octanesulfonamide, N-[3-(dimethylamino)propyl]-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro- 608-993-8 34455-22-6 - View substance registered dossier
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Active 1-oxa-4-azaspiro[4.5]decan-4-ethanol 219-101-8 2359-11-7 2019 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 617-500-5 83905-01-5 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 1-Pentanone, 1-[4-(4-propylcyclohexyl)phenyl]-, trans- 689-247-9 95149-35-2 2012; 2019 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, O-(2-aminoethyl)oxime, (1E)- 611-193-1 54739-18-3 2017 View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, oxime 612-371-1 61747-22-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Pentene, chlorinated, epoxidized, distn. residues 304-798-4 94279-53-5 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride (1:1) 606-318-1 19478-81-0 2018 View substance registered dossier
PIERRE FABRE MEDICAMENT 45 place Abel Gance 92654 Boulogne France France Active 1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one 922-915-2 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1-phenyl-3-piperidin-1-ylpropan-1-one 635-445-5 73-63-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-phenyl-3H-indol-2-one 441-020-3 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active 1-phenyl-3H-indol-2-one 441-020-3 - 2010; 2012; 2017 View substance registered dossier
Shell Nederland Chemie B.V. Chemieweg 25 PO BOX 6060, 4780 LN Moerdijk Netherlands Netherlands Active 1-phenylethanol 202-707-1 98-85-1 2012 View substance registered dossier
Lyondell Chemie Nederland B.V. Deltseplein 27E 3013 AA Rotterdam Netherlands Netherlands Active 1-phenylethanol 202-707-1 98-85-1 2014; 2020 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 1-phenylethanol 202-707-1 98-85-1 2020 View substance registered dossier
Shell Nederland Chemie B.V. Chemieweg 25 PO BOX 6060, 4780 LN Moerdijk Netherlands Netherlands Active 1-phenylethyl hydroperoxide 221-341-3 3071-32-7 2012 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 1-phenylpropan-1-ol 202-256-0 93-54-9 2016; 2019 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 1-phenylpropan-1-ol 202-256-0 93-54-9 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 1-phenyltetrazole-5-thiol 201-710-5 86-93-1 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester 695-268-4 571188-59-5 - View substance registered dossier
EXPANSIA Route d'Avignon BP 6 30390 ARAMON France France Active 1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester 695-268-4 571188-59-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester 695-268-4 571188-59-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Piperazinecarboxylic acid, 4-[(2-fluoro-3-nitrophenyl)methyl]-,methyl ester, hydrochloride (1:1) 843-886-1 1628206-32-5 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-, hydrochloride (1:2) 605-374-4 164726-80-1 - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester 935-907-9 79794-75-5 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester 935-907-9 79794-75-5 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 1-Piperidinecarboxylic acid, 4-(methylamino)-, ethyl ester 616-013-5 73733-69-4 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 2012; 2015 View substance registered dossier
[Confidential] - - - 1-Propanamine, 3-(methoxydimethylsilyl)- 608-570-8 31024-26-7 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- 806-749-7 918504-27-5 2020; 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- 806-749-7 918504-27-5 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-798-4 1262985-23-8 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-798-4 1262985-23-8 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Active 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-756-5 1262985-24-9 2020; 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- 806-756-5 1262985-24-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propanol, 3-(dimethylamino)-, hydrochloride (1:1) 601-495-1 117829-74-0 2011 View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-Propanone, 1-[2-(2-propen-1-yloxy)phenyl]- 604-312-3 142819-94-1 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 1-Propanone, 1-phenyl-3-(1-pyrrolidinyl)- 619-034-8 94-39-3 - View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active 1-Propanone, 2-methyl-1-[4-(methylthio)phenyl]- 610-979-1 53207-58-2 - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active 1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1) 609-494-8 37951-53-4 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 1-Propen-1,2,3-tricarbonsäure tris(2-(2,2,3,3,3,4,4,4-heptafluorbutoxy)-1-(methyl)-ethyl)ester - - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, 2-methyl-, chlorinated, epoxidized, distn. residues 304-801-9 94279-55-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, chlorinated, epoxidized, distn. residues 304-800-3 94279-54-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-Propene, hydroformylation products, high-boiling 271-363-2 68551-11-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-Pyrrolidinecarboxylic acid, 2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-, 1,1-dimethylethyl ester, (2S,4S)- 807-100-0 1378391-45-7 - View substance registered dossier
[Confidential] - - - 1-Pyrrolidinecarboxylic acid, 3-[2-[(ethoxycarbonyl)[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-, phenylmethyl ester, (3R,4S)- 944-343-2 2050038-81-6 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 2021 View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1-Pyrrolidinecarboxylic acid, 4-(benzoylthio)-2-[(dimethylamino)carbonyl]-, 2-propen-1-yl ester, (2S,4S)- 604-254-9 141818-73-7 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 1-tert-butoxycarbonylpiperidine-4-carboxylic acid 700-076-1 84358-13-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-tert-butyl 2,4-dimethyl (2S,4S)-pyrrolidine-1,2,4-tricarboxylate 807-497-0 1378388-30-7 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active 1-tert-butyl 2-methyl (2S,4R)-4-{[(4-methylphenyl)sulfonyl]oxy}pyrrolidine-1,2-dicarboxylate 686-032-1 88043-21-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-tert-butyl 2-methyl (2S,4S)-4-(hydroxymethyl)pyrrolidine-1,2-dicarboxylate 807-618-7 1194059-42-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium iodide hydrate (1:1:1) 606-216-7 190651-18-4 2011; 2019 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1) 615-984-2 73547-70-3 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1) 615-984-2 73547-70-3 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1) 615-984-2 73547-70-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 1-{[2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole monomethanesulfonate 617-843-0 86386-77-8 2009; 2011 View substance registered dossier
[Confidential] - - - 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 941-920-0 1628047-87-9 - View substance registered dossier
ARCHIMICA S.P.A. Viale Milano 86 26900 Lodi Italy Italy Italy Active 1-β-D-arabinofuranosylcytosine hydrochloride 200-713-9 69-74-9 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active 10,10-dimethylanthracen-9(10H)-one 226-666-4 5447-86-9 2020 View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 10,10-dimethylanthracen-9(10H)-one 226-666-4 5447-86-9 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Chemosyntha BV Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium Belgium Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Kemikos s.r.l. Via Carolina Romani, 2/A 20091 Bresso (MI) Italy Italy Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
SAFIC ALCAN 13 Cours Valmy 92977 Paris La Défense France France Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 10,11-dihydro-5H-dibenz[b,f]azepine 207-787-1 494-19-9 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 201-578-9 84-97-9 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active 10-[4-(2-chloroethyl)piperazin-1-yl]-2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaene 609-095-9 352232-17-8 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active 10-hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl) decan-1-one 700-045-2 104966-97-4 - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active 10-methoxy-1,6-dimethylergoline-8β-methanol 252-405-9 35155-28-3 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 10-methoxy-5H-dibenz[b,f]azepine 225-172-6 4698-11-7 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Cease Manufacture 10-methoxy-5H-dibenz[b,f]azepine 225-172-6 4698-11-7 2015 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid 10-methoxy-5H-dibenz[b,f]azepine 225-172-6 4698-11-7 2021 View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 10-methoxy-5H-dibenz[b,f]azepine 225-172-6 4698-11-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 10-methoxy-5H-dibenz[b,f]azepine 225-172-6 4698-11-7 2019 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 10-Undecenamide, N-[3-(dimethylamino)propyl]- 613-971-6 66654-01-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 10H-pyrido[3,2-b](1,4)benzothiazine 205-973-7 261-96-1 - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 249-227-9 28797-48-0 - View substance registered dossier
ARCHIMICA S.P.A. Viale Milano 86 26900 Lodi Italy Italy Italy Active 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 249-227-9 28797-48-0 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol 224-821-0 4504-88-5 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 11-[3-(dimethylamino)propyl]-6H-benzo[c][1]benzothiepin-11-ol 604-888-6 1531-85-7 - View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 11-[3-(dimethylamino)propyl]-6H-benzo[c][1]benzothiepin-11-ol 604-888-6 1531-85-7 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active 11-bromoundecanoic acid 220-602-9 2834-05-1 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 11-bromoundecanol 216-554-3 1611-56-9 - View substance registered dossier
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain Spain Active 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine dihydrochloride 700-276-9 111974-74-4 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine dihydrochloride 700-276-9 111974-74-4 - View substance registered dossier

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