Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104986 dossiers.
Substance identity
Administrative data
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First published date:
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Substance data
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Details
tert-butyl hypochlorite
208-072-7 507-40-4 Active Intermediate Joint Intermediate use only 14-01-2019 View substance registered dossier
tert-butyl hydroperoxide
200-915-7 75-91-2 Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 30-09-2021 View substance registered dossier
tert-butyl chloroacetate
203-506-1 107-59-5 Active Intermediate Joint Intermediate use only 23-07-2018 View substance registered dossier
tert-butyl carbazate
212-795-3 870-46-2 Active Intermediate Joint Intermediate use only 21-02-2019 View substance registered dossier
tert-butyl bromoacetate
226-133-6 5292-43-3 Active Intermediate Joint Intermediate use only 22-01-2019 View substance registered dossier
tert-butyl acrylate
216-768-7 1663-39-4 Active Full Joint ≥ 1 tonnes 15-12-2020 View substance registered dossier
tert-butyl acetate
208-760-7 540-88-5 Active Full Joint ≥ 100 to < 1 000 tonnes 05-09-2016 View substance registered dossier
tert-butyl acetate
208-760-7 540-88-5 Active Intermediate Individual Intermediate use only 14-09-2020 View substance registered dossier
tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate
920-979-6 - Active Intermediate Joint Intermediate use only 15-02-2013 View substance registered dossier
tert-butyl [(5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl]methylcarbamate
814-218-6 1643141-19-8 Active Intermediate Individual Intermediate use only 23-05-2017 View substance registered dossier
tert-butyl [(1S,3R)-3-hydroxycyclopentyl]carbamate
807-383-0 167465-99-8 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate
836-116-0 480452-36-6 Active Intermediate Joint Intermediate use only 09-10-2020 View substance registered dossier
tert-butyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)propan-2-yl]-1H-indole-3-carboxylate
812-677-7 1256584-75-4 Active Intermediate Individual Intermediate use only 07-07-2016 View substance registered dossier
tert-butyl 5'-acetyl-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate
848-453-0 1398609-81-8 Active Full Joint ≥ 1 to < 10 tonnes 26-02-2021 View substance registered dossier
tert-butyl 5'-(3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate
848-454-6 1398610-04-2 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2021 View substance registered dossier
tert-butyl 4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine-1-carboxylate
941-919-5 1228780-71-9 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
tert-butyl 4-cyanopiperidine-1-carboxylate
624-826-1 91419-52-2 Active Intermediate Joint Intermediate use only 15-07-2021 View substance registered dossier
tert-butyl 4-bromo-2-fluorobenzoate
810-257-8 889858-12-2 Active Intermediate Joint Intermediate use only 23-11-2015 View substance registered dossier
tert-butyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
942-459-8 1628047-84-6 Active Intermediate Joint Intermediate use only 23-11-2015 View substance registered dossier
tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate
- - Active Intermediate Joint Intermediate use only 21-06-2021 View substance registered dossier
tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate
859-135-6 1799799-87-3 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
TERT-BUTYL 4-({[6-AMINO-5-(4-PHENOXYPHENYL)PYRIMIDIN-4-YL]AMINO}METHYL)-4-FLUOROPIPERIDINE-1-CARBOXYLATE
941-339-2 - Active Intermediate Joint Intermediate use only 21-06-2021 View substance registered dossier
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate
810-753-4 1374639-78-7 No longer Valid Full Individual No longer valid 27-08-2019 View substance registered dossier
tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
942-231-8 1628047-90-4 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
tert-butyl 3-oxobutanoate
216-904-5 1694-31-1 Active Full Joint ≥ 10 to < 100 tonnes 07-05-2018 View substance registered dossier
tert-butyl 3-oxobutanoate
216-904-5 1694-31-1 Active Intermediate Joint Intermediate use only 26-03-2018 View substance registered dossier
Tert-butyl 3-oxoazetidine-1-carboxylate
627-725-0 398489-26-4 Cease Manufacture Intermediate Individual Cease manufacture 28-07-2014 View substance registered dossier
Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate
700-004-9 175463-32-8 Active Intermediate Individual Intermediate use only 12-02-2009 View substance registered dossier
tert-butyl 3-[6-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methylpyridin-2-yl]benzoate
800-308-2 1160221-25-9 Active Intermediate Joint Intermediate use only 21-10-2014 View substance registered dossier
tert-butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate
800-303-5 1083057-14-0 Active Intermediate Joint Intermediate use only 21-10-2014 View substance registered dossier
tert-butyl 3,5,5-trimethylperoxyhexanoate
236-050-7 13122-18-4 Active Full Joint ≥ 1 000 to < 10 000 tonnes 12-11-2020 View substance registered dossier
tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate
606-396-7 198904-86-8 Active Full Joint ≥ 1 to < 10 tonnes 24-04-2018 View substance registered dossier
tert-butyl 2-oxopyrrolidine-1-carboxylate
617-776-7 85909-08-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
tert-butyl 2-hydroxyisobutyrate
252-952-3 36293-63-7 Active Intermediate Joint Intermediate use only 08-11-2017 View substance registered dossier
tert-butyl 2-ethylperoxyhexanoate
221-110-7 3006-82-4 Active Full Joint ≥ 1 000 to < 10 000 tonnes 16-08-2021 View substance registered dossier
tert-butyl 2-bromopropanoate
675-664-3 39149-80-9 Active Intermediate Joint Intermediate use only 24-04-2018 View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
429-080-9 - Active Full Joint ≥ 1 to < 10 tonnes 12-10-2017 View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
429-080-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate
606-022-2 184177-88-6 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Active Intermediate Individual Intermediate use only 27-02-2018 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (triphenylphosphoranylidene) acetate
412-880-7 35000-38-5 Active NONS Joint Tonnage data confidential 14-07-2011 View substance registered dossier
tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate
626-262-1 35150-07-3 Active Intermediate Joint Intermediate use only 28-11-2017 View substance registered dossier
tert-butyl (6S)-6-[4-(7-{2-[(1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate ethanedioate (1:1)
941-126-4 1499193-66-6 Cease Manufacture Intermediate Joint Cease manufacture 09-06-2015 View substance registered dossier
tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
407-620-4 33610-13-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
425-780-3 125971-94-0 Active Intermediate Joint Intermediate use only 16-03-2018 View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
425-780-3 125971-94-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Active Intermediate Individual Intermediate use only 23-04-2019 View substance registered dossier
tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate
811-363-7 1681053-96-2 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Eumedica Pharmaceuticals Industries, S.L. Peña Brava Parc. 22 B-23 33192 Llanera Asturias Spain Spain Active tert-butyl hypochlorite 208-072-7 507-40-4 - View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active tert-butyl hydroperoxide 200-915-7 75-91-2 2011; 2013; 2016 View substance registered dossier
Nouryon Chemicals NV/SA Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium Belgium Active tert-butyl hydroperoxide 200-915-7 75-91-2 2019 View substance registered dossier
Lyondell Chemie Nederland B.V. Deltseplein 27E 3013 AA Rotterdam Netherlands Netherlands Active tert-butyl hydroperoxide 200-915-7 75-91-2 2012; 2014; 2015; 2016; 2017; 2018; 2019; 2021 View substance registered dossier
REACH GLOBAL SERVICES S.A Rond Point Schuman, 6 B-1040 Brussels Belgium Belgium Active tert-butyl hydroperoxide 200-915-7 75-91-2 2021 View substance registered dossier
REACH24H CONSULTING GROUP (Chinasun Specialty Products Co., Ltd.) Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active tert-butyl hydroperoxide 200-915-7 75-91-2 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl chloroacetate 203-506-1 107-59-5 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-butyl carbazate 212-795-3 870-46-2 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active tert-butyl bromoacetate 226-133-6 5292-43-3 - View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active tert-butyl acrylate 216-768-7 1663-39-4 - View substance registered dossier
Chemreach GmbH Akazienweg 30 48317 Drensteinfurt Germany Germany Active tert-butyl acrylate 216-768-7 1663-39-4 - View substance registered dossier
Du Pont de Nemours (Deutschland) GmbH Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany Germany Active tert-butyl acrylate 216-768-7 1663-39-4 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active tert-butyl acrylate 216-768-7 1663-39-4 2012; 2014; 2017 View substance registered dossier
Lyondell Chemie Nederland B.V. Deltseplein 27E 3013 AA Rotterdam Netherlands Netherlands Active tert-butyl acetate 208-760-7 540-88-5 2013; 2014; 2015; 2016 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl acetate 208-760-7 540-88-5 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate 920-979-6 - 2013 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active tert-butyl [(5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl]methylcarbamate 814-218-6 1643141-19-8 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active tert-butyl [(1S,3R)-3-hydroxycyclopentyl]carbamate 807-383-0 167465-99-8 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl [(1S,3R)-3-hydroxycyclopentyl]carbamate 807-383-0 167465-99-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate 836-116-0 480452-36-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)propan-2-yl]-1H-indole-3-carboxylate 812-677-7 1256584-75-4 - View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active tert-butyl 5'-acetyl-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 848-453-0 1398609-81-8 - View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active tert-butyl 5'-(3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 848-454-6 1398610-04-2 - View substance registered dossier
[Confidential] - - - tert-butyl 4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine-1-carboxylate 941-919-5 1228780-71-9 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-cyanopiperidine-1-carboxylate 624-826-1 91419-52-2 - View substance registered dossier
[Confidential] - - - tert-butyl 4-bromo-2-fluorobenzoate 810-257-8 889858-12-2 - View substance registered dossier
[Confidential] - - - tert-butyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate 942-459-8 1628047-84-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate - - - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate 859-135-6 1799799-87-3 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active TERT-BUTYL 4-({[6-AMINO-5-(4-PHENOXYPHENYL)PYRIMIDIN-4-YL]AMINO}METHYL)-4-FLUOROPIPERIDINE-1-CARBOXYLATE 941-339-2 - - View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate 810-753-4 1374639-78-7 2021 View substance registered dossier
[Confidential] - - - tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate 942-231-8 1628047-90-4 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2018 View substance registered dossier
Valtris Specialty Chemicals Ltd Lankro Way PO Box 1 , Eccles M30 OLX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
Lonza Cologne GmbH - REACH Nattermannallee 1 50829 Cologne Germany Germany Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2017 View substance registered dossier
Eastman Chemical B.V. Watermanweg 70 3067 GG Rotterdam Netherlands Netherlands Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
MINAKEM S.A.S. Chemin des Lilas, 145 59310 Beuvry-la-Forêt France France Cease Manufacture Tert-butyl 3-oxoazetidine-1-carboxylate 627-725-0 398489-26-4 2021 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate 700-004-9 175463-32-8 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active tert-butyl 3-[6-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methylpyridin-2-yl]benzoate 800-308-2 1160221-25-9 2014 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active tert-butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate 800-303-5 1083057-14-0 2014 View substance registered dossier
Nouryon Chemicals NV/SA Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium Belgium Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2012; 2014; 2017; 2019 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 - View substance registered dossier
PERGAN GmbH Schlavenhorst 71 46395 Bocholt NRW Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2017 View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2011; 2014; 2017; 2020 View substance registered dossier
ARKEMA Gmbh Tersteegenstrasse 28 40401 Düsseldorf Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2016; 2017 View substance registered dossier
Perga-Chem GmbH Vor dem Gröperntor 20 06484 Quedlinburg Germany Germany Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 2017 View substance registered dossier
REACH GLOBAL SERVICES S.A Rond Point Schuman, 6 B-1040 Brussels Belgium Belgium Active tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate 606-396-7 198904-86-8 2018 View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate 606-396-7 198904-86-8 2018 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate 606-396-7 198904-86-8 - View substance registered dossier
Chr. Olesen ChemPharm GmbH Gustav-Becker-Strasse 20B 21218 Seevetal Germany Germany Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl 2-hydroxyisobutyrate 252-952-3 36293-63-7 - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
ARKEMA Gmbh Tersteegenstrasse 28 40401 Düsseldorf Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2016; 2017; 2019 View substance registered dossier
Valspar b.v. Zuiveringweg 89 8243 PE Lelystad Netherlands Netherlands Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2020 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2011; 2014; 2016; 2019; 2020 View substance registered dossier
Perga-Chem GmbH Vor dem Gröperntor 20 06484 Quedlinburg Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2013; 2017 View substance registered dossier
Nouryon Chemicals NV/SA Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2012; 2013; 2017; 2019 View substance registered dossier
PERGAN GmbH Schlavenhorst 71 46395 Bocholt NRW Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 2016 View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
TSE, OR for Tosoh Finechem Rembrandt Tower Amstelplein 1 1096 HA Amsterdam Netherlands Netherlands Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active tert-butyl 2-bromopropanoate 675-664-3 39149-80-9 - View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - 2010; 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate 606-022-2 184177-88-6 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 - View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active tert-butyl (triphenylphosphoranylidene) acetate 412-880-7 35000-38-5 2011 View substance registered dossier
[Confidential] - - - tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate 626-262-1 35150-07-3 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture tert-butyl (6S)-6-[4-(7-{2-[(1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate ethanedioate (1:1) 941-126-4 1499193-66-6 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 407-620-4 33610-13-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 425-780-3 125971-94-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 425-780-3 125971-94-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 2016 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate 811-363-7 1681053-96-2 - View substance registered dossier

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