Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104986 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

0

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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
No results were found
Details
Estradiol
200-023-8 50-28-2 Active Full Joint ≥ 1 to < 10 tonnes 03-09-2018 View substance registered dossier
2,3-dichlorobenzoic acid
200-039-5 50-45-3 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
Desipramine
200-040-0 50-47-5 Active Intermediate Joint Intermediate use only 08-02-2018 View substance registered dossier
Amitriptyline
200-041-6 50-48-6 Active Intermediate Joint Intermediate use only 11-10-2018 View substance registered dossier
Imipramine
200-042-1 50-49-7 Active Intermediate Joint Intermediate use only 08-03-2018 View substance registered dossier
Thioridazine
200-044-2 50-52-2 Active Intermediate Joint Intermediate use only 19-03-2018 View substance registered dossier
Chlorpromazine
200-045-8 50-53-3 Active Intermediate Joint Intermediate use only 16-05-2017 View substance registered dossier
D-ribose
200-059-4 50-69-1 Active Full Joint ≥ 0 to < 10 tonnes 03-05-2019 View substance registered dossier
D-ribose
200-059-4 50-69-1 Active Intermediate Joint Intermediate use only 15-09-2020 View substance registered dossier
O-acetylsalicylic acid
200-064-1 50-78-2 Active Full Joint ≥ 100 to < 1 000 tonnes 02-04-2013 View substance registered dossier
O-acetylsalicylic acid
200-064-1 50-78-2 Active Intermediate Individual Intermediate use only 27-03-2015 View substance registered dossier
2-hydroxy-p-toluic acid
200-068-3 50-85-1 Cease Manufacture Full Joint Cease manufacture 15-02-2018 View substance registered dossier
2-hydroxy-p-toluic acid
200-068-3 50-85-1 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
Thymidine
200-070-4 50-89-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 02-09-2014 View substance registered dossier
α-phenyl-1H-benzimidazole-2-methanol
200-073-0 50-97-5 Active Full Joint ≥ 10 to < 100 tonnes 28-06-2019 View substance registered dossier
Ephedrine hydrochloride
200-074-6 50-98-6 Active Intermediate Joint Intermediate use only 08-11-2018 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 No longer Valid Full Individual No longer valid 02-07-2013 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 Active Full Joint Tonnage data confidential 03-02-2020 View substance registered dossier
Procaine hydrochloride
200-077-2 51-05-8 Active Intermediate Joint Intermediate use only 02-07-2018 View substance registered dossier
Benzimidazole
200-081-4 51-17-2 Active Full Joint ≥ 10 to < 100 tonnes 04-01-2019 View substance registered dossier
Fluorouracil
200-085-6 51-21-8 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2,4-dinitrophenol
200-087-7 51-28-5 Active Full Joint ≥ 100 to < 1 000 tonnes 18-03-2021 View substance registered dossier
Hyoscine
200-090-3 51-34-3 Active Full Joint ≥ 10 to < 100 tonnes 31-08-2017 View substance registered dossier
L-4-hydroxyproline
200-091-9 51-35-4 Active Full Joint ≥ 10 to < 100 tonnes 25-06-2021 View substance registered dossier
L-4-hydroxyproline
200-091-9 51-35-4 Active Intermediate Joint Intermediate use only 03-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active Estradiol 200-023-8 50-28-2 2012; 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Estradiol 200-023-8 50-28-2 2012; 2017 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 2,3-dichlorobenzoic acid 200-039-5 50-45-3 2020 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Desipramine 200-040-0 50-47-5 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active Amitriptyline 200-041-6 50-48-6 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Amitriptyline 200-041-6 50-48-6 2017 View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Amitriptyline 200-041-6 50-48-6 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active Thioridazine 200-044-2 50-52-2 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Chlorpromazine 200-045-8 50-53-3 - View substance registered dossier
LUCAS MEYER COSMETICS 13 rue Ella Maillart Campus Eiffel - Bâtiment Edison 91300 MASSY Ile-De-France France France Active D-ribose 200-059-4 50-69-1 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
QUIMDIS SAS 71, rue Anatole France 92532 Levallois-Perret France France Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
NOVACYL SAS 21 chemin de la Sauvegarde « 21 Ecully Parc » - CS 33167 69134 ECULLY CEDEX France France Active O-acetylsalicylic acid 200-064-1 50-78-2 - View substance registered dossier
Sanofi Winthrop Industrie 20, avenue Raymond Aron 92165 Antony Cedex France France Active O-acetylsalicylic acid 200-064-1 50-78-2 2015 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Cease Manufacture 2-hydroxy-p-toluic acid 200-068-3 50-85-1 2021 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active 2-hydroxy-p-toluic acid 200-068-3 50-85-1 2021 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 2-hydroxy-p-toluic acid 200-068-3 50-85-1 - View substance registered dossier
[Confidential] - - - Thymidine 200-070-4 50-89-5 - View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active α-phenyl-1H-benzimidazole-2-methanol 200-073-0 50-97-5 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Ephedrine hydrochloride 200-074-6 50-98-6 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Ephedrine hydrochloride 200-074-6 50-98-6 2018 View substance registered dossier
Copyr S.p.A. Via G. Stephenson 73 20157 Milano Italy Italy No longer Valid 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2017 View substance registered dossier
ENDURA S.p.A. Viale Pietramellara, 5 40121 Bologna Italy Italy Active 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2014; 2020 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Procaine hydrochloride 200-077-2 51-05-8 2017; 2018 View substance registered dossier
ANTIBIOTICOS DE LEON S.L. Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Benzimidazole 200-081-4 51-17-2 2017; 2018 View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active Benzimidazole 200-081-4 51-17-2 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Fluorouracil 200-085-6 51-21-8 - View substance registered dossier
JSC Grindeks Krustpils street 53 LV-1057 Riga Latvia Latvia Active Fluorouracil 200-085-6 51-21-8 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Fluorouracil 200-085-6 51-21-8 2012 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 2,4-dinitrophenol 200-087-7 51-28-5 - View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active Hyoscine 200-090-3 51-34-3 2017 View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Kyowa Hakko Europe GmbH Am Wehrhahn 50 40211 Düsseldorf Germany Germany Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Life Technologies Europe BV Kwartsweg 2 2665 NN Bleiswijk Netherlands Netherlands Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Global Life Sciences Solutions Austria GmbH & Co KG Kremplstraße 5 4061 Pasching Austria Austria Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier

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