Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose
815-962-4 1384242-56-1 Active Intermediate Joint Intermediate use only 04-12-2019 View substance registered dossier
(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol
879-204-4 1373116-05-2 Active Intermediate Joint Intermediate use only 04-02-2022 View substance registered dossier
(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate
880-367-9 1289023-67-1 Active Intermediate Joint Intermediate use only 25-02-2022 View substance registered dossier
(5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride
874-683-6 1373116-04-1 Active Intermediate Joint Intermediate use only 15-10-2021 View substance registered dossier
(5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione
700-726-4 - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(5Z)-5-benzylideneimidazolidine-2,4-dione
700-728-5 74805-60-0 Active Intermediate Joint Intermediate use only 25-02-2022 View substance registered dossier
(5Z)-6,10-dimethylundeca-5,9-dien-2-one
626-253-2 3879-26-3 Active Intermediate Joint Intermediate use only 17-03-2022 View substance registered dossier
(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one
821-898-8 39931-87-8 Active Intermediate Joint Intermediate use only 07-05-2020 View substance registered dossier
(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one
260-887-7 57664-96-7 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
(5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate
264-989-2 64643-76-1 Active Intermediate Individual Intermediate use only 03-12-2018 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
251-561-5 33522-95-1 Active Intermediate Joint Intermediate use only 16-09-2022 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
257-924-4 52446-24-9 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol
207-385-6 467-04-9 Active Intermediate Joint Intermediate use only 29-06-2022 View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride
245-549-9 23277-43-2 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride
842-055-0 2356133-42-9 Active Intermediate Individual Intermediate use only 21-08-2019 View substance registered dossier
(6-hydroxynaphthalen-2-yl)boronic acid
687-349-8 173194-95-1 Active Intermediate Individual Intermediate use only 21-12-2015 View substance registered dossier
(6-morpholin-4-ylpyrimidin-4-yl)hydrazine
691-196-2 5767-36-2 Active Intermediate Individual Intermediate use only 25-08-2014 View substance registered dossier
(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID
617-084-5 80474-45-9 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
603-081-6 125-58-6 Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid
921-925-4 - Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R*,7R*)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one
862-404-0 119520-05-7 Active Intermediate Joint Intermediate use only 24-08-2022 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester
939-996-5 689294-28-8 Active Intermediate Joint Intermediate use only 08-04-2014 View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester
939-996-5 689294-28-8 Active Intermediate Individual Intermediate use only 26-02-2014 View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride
827-945-9 107648-80-6 Active Intermediate Joint Intermediate use only 21-09-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
600-349-4 102772-66-7 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid
438-350-5 79349-82-9 Active Intermediate Joint Intermediate use only 21-12-2017 View substance registered dossier
(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-177-4 54639-48-4 Active Intermediate Joint Intermediate use only 03-06-2013 View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine
921-415-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine
918-453-6 - Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine
917-585-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-404-7 56610-72-1 Active Intermediate Joint Intermediate use only 02-11-2016 View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
239-787-2 15690-38-7 Active Intermediate Joint Intermediate use only 19-12-2018 View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
250-099-1 30246-33-4 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
258-907-4 53994-69-7 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
244-870-1 22252-43-3 Active Intermediate Joint Intermediate use only 16-12-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one
881-148-0 1455358-14-1 Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine
813-155-1 1585969-16-9 Active Intermediate Individual Intermediate use only 21-09-2016 View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
615-123-0 7055-53-0 Active Intermediate Joint Intermediate use only 28-01-2022 View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate
884-371-1 577970-31-1 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
813-979-1 65429-42-7 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Active Intermediate Joint Intermediate use only 08-10-2021 View substance registered dossier
(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione
695-945-4 - Active Intermediate Joint Intermediate use only 23-06-2022 View substance registered dossier
(7-Bromobenzofuran-5-yl)methanol
876-095-5 286836-24-6 Active Intermediate Joint Intermediate use only 24-02-2022 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin
620-069-6 945553-94-6 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
642-947-8 415927-29-6 Active Intermediate Individual Intermediate use only 04-04-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol 879-204-4 1373116-05-2 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate 880-367-9 1289023-67-1 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride 874-683-6 1373116-04-1 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 2013 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 2022 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (5Z)-6,10-dimethylundeca-5,9-dien-2-one 626-253-2 3879-26-3 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one 821-898-8 39931-87-8 2020 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one 260-887-7 57664-96-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate 264-989-2 64643-76-1 - View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2022 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride 257-924-4 52446-24-9 - View substance registered dossier
Alcaliber S.A. Ventalomar 1 45007 Toledo Toledo Spain Spain Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance The Rubicon Centre CIT Campus , Bishopstown T12 Y275 Cork Co Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance Ltd Rubicon Building, CIT Campus Bishopstown None Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 2022 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride 245-549-9 23277-43-2 - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride 842-055-0 2356133-42-9 - View substance registered dossier
[Confidential] - - - (6-hydroxynaphthalen-2-yl)boronic acid 687-349-8 173194-95-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (6-morpholin-4-ylpyrimidin-4-yl)hydrazine 691-196-2 5767-36-2 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID 617-084-5 80474-45-9 - View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one 603-081-6 125-58-6 2022 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid 921-925-4 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6R*,7R*)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 862-404-0 119520-05-7 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active (6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester 939-996-5 689294-28-8 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester 939-996-5 689294-28-8 2014 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride 827-945-9 107648-80-6 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid 438-350-5 79349-82-9 2012; 2017 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2013 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2021 View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine 921-415-1 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine 918-453-6 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine 917-585-1 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-404-7 56610-72-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 250-099-1 30246-33-4 2019 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 258-907-4 53994-69-7 2019 View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one 881-148-0 1455358-14-1 2022 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine 813-155-1 1585969-16-9 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 615-123-0 7055-53-0 2021; 2022 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate 884-371-1 577970-31-1 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 813-979-1 65429-42-7 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione 695-945-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (7-Bromobenzofuran-5-yl)methanol 876-095-5 286836-24-6 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2011; 2018 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 642-947-8 415927-29-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.