Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104986 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
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  • Consumer Uses
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  • Uses at industrial sites
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Details
Bromoethylene
209-800-6 593-60-2 Active Intermediate Joint Intermediate use only 06-06-2016 View substance registered dossier
Trimethylammonium chloride
209-810-0 593-81-7 Active Full Joint ≥ 10 to < 100 tonnes 19-12-2020 View substance registered dossier
Guanidinium thiocyanate
209-812-1 593-84-0 Active Full Joint ≥ 100 tonnes 25-08-2021 View substance registered dossier
Diguanidinium carbonate
209-813-7 593-85-1 Active Full Joint ≥ 1 000 to < 10 000 tonnes 05-10-2021 View substance registered dossier
tert-butyllithium
209-831-5 594-19-4 Active Intermediate Joint Intermediate use only 23-04-2018 View substance registered dossier
2-chloro-2-methylbutane
209-836-2 594-36-5 Active Intermediate Joint Intermediate use only 14-07-2017 View substance registered dossier
Trichloromethanesulphenyl chloride
209-840-4 594-42-3 No longer Valid Intermediate Individual No longer valid 24-07-2018 View substance registered dossier
Ethanesulphonyl chloride
209-842-5 594-44-5 Active Intermediate Joint Intermediate use only 27-10-2016 View substance registered dossier
Ethanesulphonic acid
209-843-0 594-45-6 Active Intermediate Joint Intermediate use only 28-08-2020 View substance registered dossier
2-hydroxy-2-methylpropionic acid
209-848-8 594-61-6 Active Intermediate Joint Intermediate use only 12-07-2019 View substance registered dossier
2,2,2-trichloroacetamide
209-849-3 594-65-0 Active Intermediate Joint Intermediate use only 15-09-2021 View substance registered dossier
2,2-dimethylbutyric acid
209-865-0 595-37-9 Active Intermediate Joint Intermediate use only 17-05-2013 View substance registered dossier
Algestone
209-869-2 595-77-7 Active Intermediate Joint Intermediate use only 05-03-2021 View substance registered dossier
4',5'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
209-876-0 596-03-2 Active Full Joint ≥ 1 to < 10 tonnes 20-04-2018 View substance registered dossier
3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl diacetate
209-877-6 596-09-8 Active Intermediate Joint Intermediate use only 26-02-2018 View substance registered dossier
p,p',p''-tris(diethylamino)trityl alcohol
209-886-5 596-49-6 Active Full Joint ≥ 1 to < 10 tonnes 31-01-2017 View substance registered dossier
O,O,O-triphenyl phosphorothioate
209-909-9 597-82-0 Active Full Joint ≥ 100 to < 1 000 tonnes 07-01-2021 View substance registered dossier
Bromoacetyl bromide
209-923-5 598-21-0 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
Propionyl bromide
209-924-0 598-22-1 Active Intermediate Joint Intermediate use only 03-05-2018 View substance registered dossier
sec-butyllithium
209-927-7 598-30-1 Active Intermediate Joint Intermediate use only 02-06-2021 View substance registered dossier
Methylurea
209-935-0 598-50-5 Active Full Joint ≥ 10 to < 100 tonnes 20-07-2018 View substance registered dossier
Methyl carbamate
209-939-2 598-55-0 Active Intermediate Joint Intermediate use only 27-07-2021 View substance registered dossier
Ethyldimethylamine
209-940-8 598-56-1 Active Full Joint ≥ 100 tonnes 27-05-2021 View substance registered dossier
Manganese carbonate
209-942-9 598-62-9 Active Full Joint ≥ 10 000 to < 100 000 tonnes 01-04-2021 View substance registered dossier
Manganese carbonate
209-942-9 598-62-9 Active Intermediate Individual Intermediate use only 19-02-2013 View substance registered dossier
Lead carbonate 209-943-4 598-63-0 Cease Manufacture Intermediate Joint Cease manufacture 15-09-2010 View substance registered dossier
2-bromopropionic acid
209-947-6 598-72-1 Active Intermediate Joint Intermediate use only 10-08-2020 View substance registered dossier
2-chloropropionic acid
209-952-3 598-78-7 Active Intermediate Joint Intermediate use only 28-04-2021 View substance registered dossier
1,1-dimethylurea
209-957-0 598-94-7 Active Full Joint ≥ 10 to < 100 tonnes 24-04-2020 View substance registered dossier
Methyl trichloroacetate
209-960-7 598-99-2 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
α-hydroxy-β,β-dimethyl-γ-butyrolactone
209-963-3 599-04-2 Active Full Joint ≥ 100 to < 1 000 tonnes 29-05-2020 View substance registered dossier
α-hydroxy-β,β-dimethyl-γ-butyrolactone
209-963-3 599-04-2 Active Intermediate Joint Intermediate use only 23-05-2016 View substance registered dossier
3,3'-sulphonyldianiline
209-967-5 599-61-1 Active Full Joint ≥ 100 to < 1 000 tonnes 24-05-2018 View substance registered dossier
4-(α,α-dimethylbenzyl)phenol
209-968-0 599-64-4 Active Full Joint ≥ 100 to < 1 000 tonnes 17-04-2018 View substance registered dossier
4-(α,α-dimethylbenzyl)phenol
209-968-0 599-64-4 Active Intermediate Joint Intermediate use only 10-07-2020 View substance registered dossier
Ethyl 2-bromo-2-methylpropionate
209-980-6 600-00-0 Active Intermediate Joint Intermediate use only 04-07-2018 View substance registered dossier
Pentane-2,3-dione
209-984-8 600-14-6 Active Full Individual ≥ 0 to < 10 tonnes 26-10-2019 View substance registered dossier
Methyl pyruvate
209-987-4 600-22-6 Active Intermediate Joint Intermediate use only 13-09-2017 View substance registered dossier
1,3-dichloro-2-nitrobenzene
210-009-3 601-88-7 Active Intermediate Joint Intermediate use only 08-07-2016 View substance registered dossier
1,1'-binaphthyl-2,2'-diol
210-014-0 602-09-5 Active Intermediate Joint Intermediate use only 23-05-2018 View substance registered dossier
3-nitrophthalic acid
210-030-8 603-11-2 Active Intermediate Joint Intermediate use only 06-07-2018 View substance registered dossier
Triphenylphosphine
210-036-0 603-35-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 03-08-2021 View substance registered dossier
Triphenylphosphine
210-036-0 603-35-0 Active Intermediate Joint Intermediate use only 10-09-2020 View substance registered dossier
4,4'-benzylidenedianiline
210-038-1 603-40-7 Active Intermediate Joint Intermediate use only 27-06-2018 View substance registered dossier
p,p'-(2-pyridylmethylene)bisphenol
210-039-7 603-41-8 Active Intermediate Joint Intermediate use only 29-05-2017 View substance registered dossier
4-[[4-(dimethylamino)phenyl][4-(methylimino)cyclohexa-2,5-dien-1-ylidene]methyl]-N,N-dimethylaniline monohydrochloride
210-042-3 603-47-4 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline
210-043-9 603-48-5 Active Full Joint ≥ 1 to < 10 tonnes 11-11-2019 View substance registered dossier
Ethyl diphenylcarbamate
210-047-0 603-52-1 Active Full Joint ≥ 1 to < 10 tonnes 14-12-2017 View substance registered dossier
17β-hydroxy-1α-methylandrost-4-ene-3-one
210-063-8 604-26-2 Active Intermediate Joint Intermediate use only 27-05-2020 View substance registered dossier
Cholest-5-en-3-β-yl acetate
210-066-4 604-35-3 Active Full Joint ≥ 1 to < 10 tonnes 21-09-2021 View substance registered dossier
α-D-glucose pentaacetate
210-073-2 604-68-2 Active Full Joint ≥ 1 to < 10 tonnes 19-03-2018 View substance registered dossier
β-D-glucose pentaacetate
210-074-8 604-69-3 Active Intermediate Joint Intermediate use only 11-05-2018 View substance registered dossier
diisopentylphthalate
210-088-4 605-50-5 Cease Manufacture Full Individual Cease manufacture 25-03-2021 View substance registered dossier
Naphthalene-1,4-dicarboxylic acid
210-094-7 605-70-9 Active Intermediate Joint Intermediate use only 28-05-2019 View substance registered dossier
1,5-dinitronaphthalene
210-095-2 605-71-0 Active Full Joint ≥ 1 to < 10 tonnes 15-10-2019 View substance registered dossier
Methyl 2-benzoylbenzoate
210-112-3 606-28-0 Active Full Joint ≥ 100 to < 1 000 tonnes 07-01-2020 View substance registered dossier
Dihydronicotinamide-adenine dinucleotide, disodium salt
210-123-3 606-68-8 Active Full Joint ≥ 1 to < 10 tonnes 23-03-2018 View substance registered dossier
Diethyl benzylmalonate
210-142-7 607-81-8 Active Intermediate Joint Intermediate use only 17-01-2018 View substance registered dossier
2-(5-methoxyindol-3-yl)ethylamine
210-153-7 608-07-1 Active Intermediate Individual Intermediate use only 09-06-2017 View substance registered dossier
2-methylresorcinol
210-155-8 608-25-3 Active Full Joint ≥ 100 to < 1 000 tonnes 04-03-2021 View substance registered dossier
2,3-dichloroaniline
210-157-9 608-27-5 Active Intermediate Joint Intermediate use only 31-03-2011 View substance registered dossier
2,6-dichloroaniline
210-160-5 608-31-1 Active Intermediate Joint Intermediate use only 06-03-2017 View substance registered dossier
2,4-dinitromesitylene
210-164-7 608-50-4 Active Intermediate Joint Intermediate use only 25-01-2021 View substance registered dossier
Diethyl methylmalonate
210-175-7 609-08-5 Active Intermediate Joint Intermediate use only 13-03-2018 View substance registered dossier
Ethyl 2-bromo-3-methylbutyrate
210-178-3 609-12-1 Active Intermediate Joint Intermediate use only 22-04-2020 View substance registered dossier
Ethyl 2-chloroacetoacetate
210-180-4 609-15-4 Active Intermediate Individual Intermediate use only 25-10-2011 View substance registered dossier
Ethyl 2-chloroacetoacetate
210-180-4 609-15-4 Active Intermediate Joint Intermediate use only 06-03-2020 View substance registered dossier
2-nitrothiophene
210-190-9 609-40-5 Active Intermediate Joint Intermediate use only 10-12-2019 View substance registered dossier
2-chlorobenzoyl chloride
210-194-0 609-65-4 Active Intermediate Joint Intermediate use only 28-05-2021 View substance registered dossier
2-chlorobenzamide
210-195-6 609-66-5 Active Intermediate Individual Intermediate use only 03-07-2013 View substance registered dossier
3,5-dinitrosalicylic acid
210-204-3 609-99-4 Active Intermediate Joint Intermediate use only 01-09-2017 View substance registered dossier
2',4'-dinitroacetanilide
210-227-9 610-53-7 Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
2-nitrophenyl acetate
210-233-1 610-69-5 Active Full Joint ≥ 1 to < 10 tonnes 12-04-2016 View substance registered dossier
4-amino-3-nitrophenol
210-236-8 610-81-1 Active Full Joint ≥ 1 to < 10 tonnes 14-03-2018 View substance registered dossier
Methyl 2-iodobenzoate
210-243-6 610-97-9 No longer Valid Intermediate Joint No longer valid 11-05-2018 View substance registered dossier
2'-hydroxypropiophenone
210-244-1 610-99-1 Active Intermediate Joint Intermediate use only 26-11-2015 View substance registered dossier
1,3-dichloro-4-nitrobenzene
210-248-3 611-06-3 Active Intermediate Joint Intermediate use only 30-11-2017 View substance registered dossier
5-chloro-2-nitrophenol
210-249-9 611-07-4 Cease Manufacture Intermediate Joint Cease manufacture 22-05-2013 View substance registered dossier
α,2-dichlorotoluene
210-258-8 611-19-8 Active Intermediate Joint Intermediate use only 01-03-2018 View substance registered dossier
Salicylonitrile
210-259-3 611-20-1 Active Intermediate Joint Intermediate use only 11-12-2020 View substance registered dossier
Isobutyrophenone
210-275-0 611-70-1 Active Intermediate Joint Intermediate use only 18-11-2019 View substance registered dossier
L-2-hydroxy-2-phenylacetic acid
210-276-6 611-71-2 Active Intermediate Joint Intermediate use only 30-07-2021 View substance registered dossier
N,N-dimethylbenzamide
210-279-2 611-74-5 Active Intermediate Joint Intermediate use only 11-12-2018 View substance registered dossier
1,3-dimethyl-1,3-diphenylurea
210-283-4 611-92-7 Active Full Joint ≥ 0 to < 10 tonnes 25-01-2019 View substance registered dossier
4,4'-dihydroxybenzophenone
210-288-1 611-99-4 Active Full Joint ≥ 10 to < 100 tonnes 14-04-2018 View substance registered dossier
1,2-bis(chloromethyl)benzene
210-291-8 612-12-4 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
2-methoxybenzyl alcohol
210-296-5 612-16-8 Active Full Joint ≥ 1 to < 10 tonnes 21-12-2017 View substance registered dossier
N-methyl-2-nitroaniline
210-303-1 612-28-2 Active Intermediate Joint Intermediate use only 05-09-2019 View substance registered dossier
2-[(2-aminobenzoyl)amino]benzoic acid
210-304-7 612-34-0 Active Intermediate Joint Intermediate use only 23-10-2019 View substance registered dossier
3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 Active Intermediate Joint Intermediate use only 30-05-2013 View substance registered dossier
4,4'-dimethylbiphenyl
210-337-7 613-33-2 Active Intermediate Joint Intermediate use only 10-04-2018 View substance registered dossier
o-phenylenediacetonitrile
210-351-3 613-73-0 Active Intermediate Joint Intermediate use only 29-08-2017 View substance registered dossier
Benzamide oxime
210-361-8 613-92-3 Active Intermediate Joint Intermediate use only 22-11-2012 View substance registered dossier
Benzamide oxime
210-361-8 613-92-3 Active Intermediate Joint Intermediate use only 11-11-2015 View substance registered dossier
Ethyl nicotinate
210-370-7 614-18-6 Active Full Joint ≥ 10 to < 100 tonnes 08-03-2019 View substance registered dossier
Glycerol tribenzoate
210-379-6 614-33-5 Active Full Joint ≥ 1 to < 10 tonnes 04-01-2021 View substance registered dossier
tert-butyl perbenzoate
210-382-2 614-45-9 Active Full Joint ≥ 1 000 to < 10 000 tonnes 14-08-2020 View substance registered dossier
Indan-2-one
210-410-3 615-13-4 Active Intermediate Joint Intermediate use only 25-03-2021 View substance registered dossier
2-hydroxybenzimidazole
210-412-4 615-16-7 Active Intermediate Joint Intermediate use only 13-08-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Bromoethylene 209-800-6 593-60-2 2012; 2016 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy No longer Valid Bromoethylene 209-800-6 593-60-2 2012 View substance registered dossier
Taminco Germany GmbH Postfach 11 11 06234 Leuna Germany Germany Active Trimethylammonium chloride 209-810-0 593-81-7 2011; 2016; 2020 View substance registered dossier
BALCHEM Italia srl Via del Porto snc 28040 Marano Ticino Novara Italy Italy Active Trimethylammonium chloride 209-810-0 593-81-7 2014 View substance registered dossier
Dinox Handels-GmbH Brüdertor 3 59494 Soest Germany Germany Active Trimethylammonium chloride 209-810-0 593-81-7 2012 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Trimethylammonium chloride 209-810-0 593-81-7 2014; 2016; 2020 View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France France Active Trimethylammonium chloride 209-810-0 593-81-7 - View substance registered dossier
Taminco BV Pantserschipstraat 207 9000 Gent Belgium Belgium Active Trimethylammonium chloride 209-810-0 593-81-7 2012; 2016; 2020 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 2021 View substance registered dossier
AMSilk GmbH Am Klopferspitz 19 Im IZB 82152 Planegg Bavaria Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Roche Diagnostics Deutschland GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
LGC Genomics Ltd Units 1-2 Trident Industrial Estate Pindar Road EN11 0WZ Hoddesdon United Kingdom United Kingdom No longer Valid Guanidinium thiocyanate 209-812-1 593-84-0 2021 View substance registered dossier
Acros Organics bv Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium Belgium Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Abbott Diagnostics GmbH Max Planck Ring 2 D-65205 Delkenheim Hessen Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 2020 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 2020 View substance registered dossier
AppliChem GmbH Ottoweg 4 64291 Darmstadt Hessen Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Guanidinium thiocyanate 209-812-1 593-84-0 2021 View substance registered dossier
Thermo Fisher Scientific Baltics UAB V.A.Graiciuno 8 LT-02241 Vilnius Lithuania Lithuania Active Guanidinium thiocyanate 209-812-1 593-84-0 2020 View substance registered dossier
MACHEREY-NAGEL GmbH & Co. KG Neumann-Neander-Str. 6-8 52355 Dueren NRW Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
PerkinElmer Health Sciences B.V. Rigaweg 22 9723 TH Groningen Groningen Netherlands Netherlands Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 2019 View substance registered dossier
HH Compliance The Rubicon Centre, CIT Campus, Bishopstown, Cork Ireland Ireland Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Biosynth s.r.o. Nobelova 34 83605 Bratislava Slovakia Slovakia Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
J.A.Moeller GmbH & Co.KG Müllenhofweg 44A 22607 Hamburg Germany Germany Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
VWR International BV Haasrode Researchpark 2020 3001 Leuven Belgium Belgium Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany No longer Valid Guanidinium thiocyanate 209-812-1 593-84-0 2018; 2021 View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France France Active Guanidinium thiocyanate 209-812-1 593-84-0 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
Borealis Agrolinz Melamine GmbH St. Peter-Str. 25 4021 Linz Austria Austria Active Diguanidinium carbonate 209-813-7 593-85-1 2013; 2016 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
Knoell NL-OR-S07 Agro Business Park 75 6708 PV Wageningen Netherlands Netherlands Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
CTF2000 Baaikensstraat 11 9240 Zele Oost-Vlaanderen Belgium Belgium Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
L'OREAL 14 rue Royale 75008 Paris France France Active Diguanidinium carbonate 209-813-7 593-85-1 2021 View substance registered dossier
L OREAL UK LTD 255, Hammersmith Road W6 8AZ LONDON United Kingdom United Kingdom No longer Valid Diguanidinium carbonate 209-813-7 593-85-1 2021 View substance registered dossier
Archroma France, SAS Rue du Flottage 60350 Trosly-Breuil France France Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
Schill + Seilacher GmbH Schoenaicher Str. 205 71032 Boeblingen Germany Germany Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
LASCAD 7 rue Touzet 93400 Saint Ouen France France Active Diguanidinium carbonate 209-813-7 593-85-1 - View substance registered dossier
Merck Schuchardt OHG Eduard-Buchner-Str. 85662 Hohenbrunn Germany Germany Active Diguanidinium carbonate 209-813-7 593-85-1 2021 View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active tert-butyllithium 209-831-5 594-19-4 - View substance registered dossier
FMC Chemicals Ltd Wirral International Business Park Commercial Road CH62 3NL Bromborough Wirral United Kingdom United Kingdom No longer Valid tert-butyllithium 209-831-5 594-19-4 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 2-chloro-2-methylbutane 209-836-2 594-36-5 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid Trichloromethanesulphenyl chloride 209-840-4 594-42-3 2021 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Ethanesulphonyl chloride 209-842-5 594-44-5 - View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active Ethanesulphonyl chloride 209-842-5 594-44-5 2016 View substance registered dossier
SurfactGreen Carrefour Jean Monnet BP 20101 60201 COMPIEGNE France France Active Ethanesulphonic acid 209-843-0 594-45-6 - View substance registered dossier
CABB Oy (OR of CABB AG) Kemirantie 1 P.O.Box 566 Kokkola Finland Finland Active Ethanesulphonic acid 209-843-0 594-45-6 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active Ethanesulphonic acid 209-843-0 594-45-6 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active Ethanesulphonic acid 209-843-0 594-45-6 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-hydroxy-2-methylpropionic acid 209-848-8 594-61-6 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2-hydroxy-2-methylpropionic acid 209-848-8 594-61-6 - View substance registered dossier
Lučební závody Draslovka a.s. Kolín Havlíčkova 605 280 02 Kolín IV Czech Republic Czech Republic Active 2-hydroxy-2-methylpropionic acid 209-848-8 594-61-6 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active 2,2,2-trichloroacetamide 209-849-3 594-65-0 2019 View substance registered dossier
UMCO GmbH Georg-Wilhelm-Straße 187 21107 Hamburg Germany Germany Active 2,2,2-trichloroacetamide 209-849-3 594-65-0 2020 View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active 2,2,2-trichloroacetamide 209-849-3 594-65-0 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2,2,2-trichloroacetamide 209-849-3 594-65-0 - View substance registered dossier
Hexion VAD B.V. Seattleweg 17 building 4 3195ND Pernis Rotterdam Netherlands Netherlands Active 2,2-dimethylbutyric acid 209-865-0 595-37-9 - View substance registered dossier
Monument Chemical Haven 1972 Ketenislaan 3 9130 Kallo Belgium Belgium Active 2,2-dimethylbutyric acid 209-865-0 595-37-9 - View substance registered dossier
Steroid SpA Viale Spagna 156 20093 Cologno Monzese Milano Italy Italy Active Algestone 209-869-2 595-77-7 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4',5'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one 209-876-0 596-03-2 2017; 2018 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl diacetate 209-877-6 596-09-8 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active p,p',p''-tris(diethylamino)trityl alcohol 209-886-5 596-49-6 - View substance registered dossier
Metall-Chemie GmbH & Co. KG Kaiser-Wilhelm-Str.93 20355 Hamburg Germany Germany Active O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 2021 View substance registered dossier
[Confidential] - - - O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 - View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 2014; 2016; 2020 View substance registered dossier
LISAM TELEGIS Parc d'activités de Noyon-Passel 17 rue de la Couture 60400 PASSEL France France Active O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 - View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 2015 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 2014; 2016; 2019; 2020 View substance registered dossier
Sungate EU B.V. Koningin Julianaplein 10, 1, 2595 AA S 2595 AA The Hague Netherlands Netherlands No longer Valid O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Bromoacetyl bromide 209-923-5 598-21-0 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Bromoacetyl bromide 209-923-5 598-21-0 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active Bromoacetyl bromide 209-923-5 598-21-0 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Bromoacetyl bromide 209-923-5 598-21-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Bromoacetyl bromide 209-923-5 598-21-0 - View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid Bromoacetyl bromide 209-923-5 598-21-0 2021 View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Propionyl bromide 209-924-0 598-22-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active Propionyl bromide 209-924-0 598-22-1 - View substance registered dossier
Albemarle U.S., Inc. Industriepark Höchst Gebäude G 879 D-65926 Frankfurt Germany Germany Active sec-butyllithium 209-927-7 598-30-1 - View substance registered dossier
Rockwood Lithium Taiwan Co., Ltd. Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active sec-butyllithium 209-927-7 598-30-1 - View substance registered dossier
FMC Lithium Foreign HoldCo B.V Prins Bernhardplein 200 1097JB Amsterdam Netherlands Netherlands Active sec-butyllithium 209-927-7 598-30-1 2021 View substance registered dossier
Rockwood Lithium India Private Limited Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active sec-butyllithium 209-927-7 598-30-1 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active sec-butyllithium 209-927-7 598-30-1 2012 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Methylurea 209-935-0 598-50-5 2015 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active Methylurea 209-935-0 598-50-5 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Methyl carbamate 209-939-2 598-55-0 - View substance registered dossier
Momentive Performance Materials GmbH Chempark Building V7 51368 Leverkusen NRW Germany Germany Active Methyl carbamate 209-939-2 598-55-0 - View substance registered dossier
Allnex Belgium NV/SA OR1 Anderlechtstraat 33 1620 Drogenbos Belgium Belgium Active Methyl carbamate 209-939-2 598-55-0 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Methyl carbamate 209-939-2 598-55-0 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Methyl carbamate 209-939-2 598-55-0 2016 View substance registered dossier
IDESA EUROPE, S.L. Calle Alboraya nº 42, puerta 2 46010 Valencia Spain Spain Active Ethyldimethylamine 209-940-8 598-56-1 - View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active Ethyldimethylamine 209-940-8 598-56-1 2010; 2012; 2019; 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyldimethylamine 209-940-8 598-56-1 2012; 2013; 2019 View substance registered dossier
SCL ITALIA S.P.A. Via Fabio Filzi 25/A 20124 Milan Italy Italy Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
BLUESTONE METALS & CHEMICALS EUROPE S.L. c/ Pascual y Genis 1 46002 Valencia Spain Spain Active Manganese carbonate 209-942-9 598-62-9 2020 View substance registered dossier
Prince Minerals SRL rue du bois 7334 Villerot (Saint-Ghislain) Belgium Belgium Active Manganese carbonate 209-942-9 598-62-9 2014; 2017; 2021 View substance registered dossier
ITACA, S.A. Partida Rambleta s/n 12191 Pobla Tornesa Castellón Spain Spain Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
TODINI AND CO. SPA Corso Milano 46 B 20900 MONZA ITALIA Italy Italy Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
REACHLaw Ltd. Vänrikinkuja 3 JK 21 FI-02600 Espooo Finland Finland Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
ALTICHEM 4 Rue Jacques Vaucanson 95310 SAINT-OUEN-L'AUMÔNE VAL D'OISE France France Active Manganese carbonate 209-942-9 598-62-9 2015; 2018 View substance registered dossier
INTERTEK FRANCE ZI ECOPARC II 27400 HEUDEBOUVILLE France France Cease Manufacture Manganese carbonate 209-942-9 598-62-9 2019 View substance registered dossier
Gentrochema BV Lage Ham 190 5102 AE Dongen Netherlands Netherlands Active Manganese carbonate 209-942-9 598-62-9 2018 View substance registered dossier
Johnson Matthey Chemicals GmbH Wardstrasse 17 D-46446 Emmerich am Rhein Germany Germany Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
TRADE CORPORATION INTERNATIONAL S.A.U Vía de los Poblados 3, Parque Empresarial Cristalia, Edif. Onic 5, 6th floor 28033 Madrid Spain Spain Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
Norkem BV Het Voert 7 1613 KL Grootebroek Netherlands Netherlands Active Manganese carbonate 209-942-9 598-62-9 2018 View substance registered dossier
cfm minerales Camino de palos s/n. aptdo.345 12200 Onda Spain Spain Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
Yara International ASA OR7 Drammensveien 131 0277 Oslo Norway Norway Active Manganese carbonate 209-942-9 598-62-9 2011; 2018; 2020 View substance registered dossier
S.Goldmann GmbH & Co. KG Schillerstr. 79 33609 Bielefeld Germany Germany Active Manganese carbonate 209-942-9 598-62-9 2018 View substance registered dossier
Atanor Productos Químicos S.A. C/ Pau Alcover, 52, Bajos 08017 Barcelona Spain Spain Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark Active Manganese carbonate 209-942-9 598-62-9 2021 View substance registered dossier
Przedsiębiorstwo Produkcyjno- Consultingowe ADOB Sp. z o.o. Sp. jawna Kołodzieja 11 61-070 Poznań Poland Poland Poland Active Manganese carbonate 209-942-9 598-62-9 - View substance registered dossier
Umicore NV/SA Rue du Marais 31 1000 Brussels Belgium Belgium Cease Manufacture Lead carbonate 209-943-4 598-63-0 2012 View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active 2-bromopropionic acid 209-947-6 598-72-1 - View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid 2-bromopropionic acid 209-947-6 598-72-1 2021 View substance registered dossier
Vynova PPC SAS 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France France Active 2-bromopropionic acid 209-947-6 598-72-1 2013 View substance registered dossier
CABB Oy (OR of CABB AG) Kemirantie 1 P.O.Box 566 Kokkola Finland Finland Active 2-chloropropionic acid 209-952-3 598-78-7 2020 View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 2-chloropropionic acid 209-952-3 598-78-7 2013; 2021 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 1,1-dimethylurea 209-957-0 598-94-7 2020 View substance registered dossier
CABB GmbH Ludwig-Hermann-Str. 100 86368 Gersthofen Germany Germany Cease Manufacture Methyl trichloroacetate 209-960-7 598-99-2 2020 View substance registered dossier
UMCO GmbH Georg-Wilhelm-Straße 187 21107 Hamburg Germany Germany Active Methyl trichloroacetate 209-960-7 598-99-2 2020 View substance registered dossier
DSM Nutritional Products GmbH-OR18 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active α-hydroxy-β,β-dimethyl-γ-butyrolactone 209-963-3 599-04-2 2013; 2014; 2019; 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active α-hydroxy-β,β-dimethyl-γ-butyrolactone 209-963-3 599-04-2 2011; 2016 View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 6 91301 Forchheim Germany Germany Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 - View substance registered dossier
Henkel Global Supply Chain B.V. Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands Netherlands Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 - View substance registered dossier
ATUL IRELAND LIMITED OR Flynn O'driscoll No.1 Grant's Row Lower Mount Street D02HX96 DUBLIN DUBLIN Ireland Ireland Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 2018 View substance registered dossier
Mitsui & Co. Europe Plc, Paris Branch. 112 Avenue Kleber 75116 Paris France France Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 2018 View substance registered dossier
Huntsman Advanced Materials (Europe) BV Everslaan 45 B-3078 Everberg Belgium Belgium Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 2014; 2017 View substance registered dossier
Intertek Deutschland GmbH CHJC Stangenstr. 1 70771 Leinfelden-Echterdingen Germany Germany Active 3,3'-sulphonyldianiline 209-967-5 599-61-1 - View substance registered dossier
Sasol Germany GmbH Anckelmannsplatz 1 D-20537 Hamburg Germany Germany Active 4-(α,α-dimethylbenzyl)phenol 209-968-0 599-64-4 2018 View substance registered dossier
SABIC Innovative Plastics BV Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands Netherlands Active 4-(α,α-dimethylbenzyl)phenol 209-968-0 599-64-4 2012; 2015 View substance registered dossier
SHPP B.V. Plasticslaan 1 4612PX Bergen op Zoom Netherlands Netherlands Active 4-(α,α-dimethylbenzyl)phenol 209-968-0 599-64-4 - View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Ethyl 2-bromo-2-methylpropionate 209-980-6 600-00-0 2012 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Ethyl 2-bromo-2-methylpropionate 209-980-6 600-00-0 2012; 2016; 2017; 2018 View substance registered dossier
Vynova PPC SAS 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France France Active Ethyl 2-bromo-2-methylpropionate 209-980-6 600-00-0 2012 View substance registered dossier
IFFORFrutarom Liebergerweg 72-98 1221JT Hilversum Noord Holland Netherlands Netherlands Active Pentane-2,3-dione 209-984-8 600-14-6 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 154 Parque Empresarial Las Tablas, Edifico 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active Methyl pyruvate 209-987-4 600-22-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Methyl pyruvate 209-987-4 600-22-6 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,3-dichloro-2-nitrobenzene 210-009-3 601-88-7 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active 1,1'-binaphthyl-2,2'-diol 210-014-0 602-09-5 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 3-nitrophthalic acid 210-030-8 603-11-2 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active 3-nitrophthalic acid 210-030-8 603-11-2 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active 3-nitrophthalic acid 210-030-8 603-11-2 - View substance registered dossier
Afton Chemical S.R.L. (Woluwe) Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium Belgium Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
A V Pound & Co. Ltd Goolds Hill House Old Cork Road Ireland Mallow Co. Cork Ireland Ireland Active Triphenylphosphine 210-036-0 603-35-0 2019 View substance registered dossier
Vesta Chemicals bv Dr. van Wiechenweg 8A 8025 BZ ZWOLLE Netherlands, The Netherlands Netherlands Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Triphenylphosphine 210-036-0 603-35-0 2011; 2012; 2014; 2015; 2019; 2020 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Triphenylphosphine 210-036-0 603-35-0 2021 View substance registered dossier
RSI ChemRep Europe Ltd (H002) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active Triphenylphosphine 210-036-0 603-35-0 2016; 2019 View substance registered dossier
RSI ChemRep Europe Ltd (Z002) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active Triphenylphosphine 210-036-0 603-35-0 2016; 2019 View substance registered dossier
Novasol S.A. Mechelsesteenweg 455 1950 Kraainem Belgium Belgium Active Triphenylphosphine 210-036-0 603-35-0 2020 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Triphenylphosphine 210-036-0 603-35-0 2017 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
S.I.M.S. S.r.l. Località Filarone 50066 Reggello (FI) Italy Italy Active Triphenylphosphine 210-036-0 603-35-0 2019 View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
Arcerion GmbH Gabrielenstr. 15 80636 München Germany Germany Active Triphenylphosphine 210-036-0 603-35-0 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 4,4'-benzylidenedianiline 210-038-1 603-40-7 2018 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active p,p'-(2-pyridylmethylene)bisphenol 210-039-7 603-41-8 2016 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active p,p'-(2-pyridylmethylene)bisphenol 210-039-7 603-41-8 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active p,p'-(2-pyridylmethylene)bisphenol 210-039-7 603-41-8 - View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 4-[[4-(dimethylamino)phenyl][4-(methylimino)cyclohexa-2,5-dien-1-ylidene]methyl]-N,N-dimethylaniline monohydrochloride 210-042-3 603-47-4 - View substance registered dossier
Du Pont (U.K.) Limited London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom United Kingdom No longer Valid N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline 210-043-9 603-48-5 2021 View substance registered dossier
Luxcontrol S.A. (OR51) 1, Avenue des Terres Rouges 4331 Esch-sur-Alzette Luxembourg Luxembourg Active N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline 210-043-9 603-48-5 - View substance registered dossier
Du Pont de Nemours (Deutschland) GmbH Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany Germany Active N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline 210-043-9 603-48-5 - View substance registered dossier
Nitrochemie Aschau GmbH Liebigstrasse 17 84544 Aschau am Inn Germany Germany Active Ethyl diphenylcarbamate 210-047-0 603-52-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 17β-hydroxy-1α-methylandrost-4-ene-3-one 210-063-8 604-26-2 2020 View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active Cholest-5-en-3-β-yl acetate 210-066-4 604-35-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Cholest-5-en-3-β-yl acetate 210-066-4 604-35-3 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active α-D-glucose pentaacetate 210-073-2 604-68-2 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active β-D-glucose pentaacetate 210-074-8 604-69-3 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active β-D-glucose pentaacetate 210-074-8 604-69-3 - View substance registered dossier
EURENCO Bofors AB Kontorsvägen 6 SE-691 86 Karlskoga Sweden Sweden Cease Manufacture diisopentylphthalate 210-088-4 605-50-5 2021 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active Naphthalene-1,4-dicarboxylic acid 210-094-7 605-70-9 2019 View substance registered dossier
LCW - SENSIENT COSMETIC TECHNOLOGIES 7-9, Rue de l'Industrie 95310 Saint Ouen L'Aumône Val d'Oise France France Active 1,5-dinitronaphthalene 210-095-2 605-71-0 - View substance registered dossier
Sensient Colors Oldmedow Road PE30 4LA King's Lynn Norfolk United Kingdom United Kingdom No longer Valid 1,5-dinitronaphthalene 210-095-2 605-71-0 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Dublin Ireland Ireland Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland Ireland Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 2019 View substance registered dossier
IGM Resins B.V. Gompenstraat 49 5145 RA Waalwijk Netherlands Netherlands Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 2020 View substance registered dossier
RAHN NL B.V. (30) Westplein 11 3016BM Rotterdam Netherlands Netherlands Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 - View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 - View substance registered dossier
RAHN (3) Hahnstrasse 70 D-60528 Frankfurt am Main Germany Germany Active Methyl 2-benzoylbenzoate 210-112-3 606-28-0 2018 View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Dihydronicotinamide-adenine dinucleotide, disodium salt 210-123-3 606-68-8 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Diethyl benzylmalonate 210-142-7 607-81-8 2018 View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active Diethyl benzylmalonate 210-142-7 607-81-8 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 2-(5-methoxyindol-3-yl)ethylamine 210-153-7 608-07-1 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
SD CHEMICALS via Ozanam 4 20811 Cesano Maderno Italy Italy Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
Dragon Chemical Europe GmbH Carlsplatz 24 40213 Düsseldorf Germany Germany Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
Intertek Deutschland GmbH CJXB Stangenstr.1 70771 Leinfelden-Echterdingen Germany Germany Germany Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
DEIMOS S.R.L. Viale Emilia 92/94 20093 Cologno Monzese Milan Italy Italy Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
VKG Oil AS Järveküla tee 14 30328 Kohtla-Järve Estonia Estonia Estonia Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
James Robinson Speciality Ingredients BV Office 12.15 Millenium Tower Radarweg 29 / 12B 1043NX Amsterdam Netherlands Netherlands Active 2-methylresorcinol 210-155-8 608-25-3 2019; 2021 View substance registered dossier
Stadex Nederland BV Boxbergerweg 119 7431PM Diepenveen Netherlands Netherlands Active 2-methylresorcinol 210-155-8 608-25-3 2014; 2015; 2016; 2018 View substance registered dossier
Jos. H. Lowenstein & Sons B.V. Naritaweg 165 1043 BW Amsterdam Netherlands Netherlands Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
Artec Europe BV Vivaldistraat 3 7132 AG Lichtenvoorde Netherlands Netherlands Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED ROOM 002, REGUS HARCOURT CENTRE D02 HW77 D02 DUBLIN Ireland Ireland Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 2-methylresorcinol 210-155-8 608-25-3 2018 View substance registered dossier
Amik Italia VIA MECENATE 84B 20138 MILANO Italy Italy Italy Active 2-methylresorcinol 210-155-8 608-25-3 2019 View substance registered dossier
ExponentOR21I Block 1, Blanchardstown Corporate Park Ballycoolen Road, Blanchardstown D15 AKK1 Dublin Ireland Ireland Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
COSMOLIFE SAS 25 rue des ALOUETTES 95150 TAVERNY France France Active 2-methylresorcinol 210-155-8 608-25-3 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active 2,3-dichloroaniline 210-157-9 608-27-5 2011 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 2,6-dichloroaniline 210-160-5 608-31-1 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 2,4-dinitromesitylene 210-164-7 608-50-4 2021 View substance registered dossier
LA FENICE TRADING SRL VIA BERGAMO 18 20900 MONZA (MILANO) LOMBARDIA Italy Italy Cease Manufacture Diethyl methylmalonate 210-175-7 609-08-5 2019 View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active Diethyl methylmalonate 210-175-7 609-08-5 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active Diethyl methylmalonate 210-175-7 609-08-5 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active Diethyl methylmalonate 210-175-7 609-08-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active Diethyl methylmalonate 210-175-7 609-08-5 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 2-bromo-3-methylbutyrate 210-178-3 609-12-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 - View substance registered dossier
CABB Oy (OR of CABB AG) Kemirantie 1 P.O.Box 566 Kokkola Finland Finland Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 2020 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active Ethyl 2-chloroacetoacetate 210-180-4 609-15-4 2012; 2013; 2015; 2019 View substance registered dossier
Chemservice S.A. (V3S9) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active 2-nitrothiophene 210-190-9 609-40-5 - View substance registered dossier
CAFFARO INDUSTRIE S.P.A P.le Marinotti, 1 33050 Torviscosa Udine Italy Italy Active 2-chlorobenzoyl chloride 210-194-0 609-65-4 - View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A. Industrial area of Patras, Building block 1 25018 Patras Greece Greece Active 2-chlorobenzoyl chloride 210-194-0 609-65-4 - View substance registered dossier
WeylChem Höchst GmbH Brüningstr. 50 D-65929 Frankfurt am Main Germany Germany Active 2-chlorobenzoyl chloride 210-194-0 609-65-4 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-chlorobenzamide 210-195-6 609-66-5 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 3,5-dinitrosalicylic acid 210-204-3 609-99-4 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 3,5-dinitrosalicylic acid 210-204-3 609-99-4 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 2',4'-dinitroacetanilide 210-227-9 610-53-7 - View substance registered dossier
AGRA GROUP a.s. Tovarni 201 387 15 Strelske Hostice Czech Republic Czech Republic Czech Republic Active 2-nitrophenyl acetate 210-233-1 610-69-5 - View substance registered dossier
Dragon Chemical Europe GmbH Carlsplatz 24 40213 Düsseldorf Germany Germany Active 4-amino-3-nitrophenol 210-236-8 610-81-1 - View substance registered dossier
Wychem Limited Bury Road CB8 8YN Stradishall Suffolk United Kingdom United Kingdom No longer Valid Methyl 2-iodobenzoate 210-243-6 610-97-9 2021 View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 2'-hydroxypropiophenone 210-244-1 610-99-1 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active 1,3-dichloro-4-nitrobenzene 210-248-3 611-06-3 2010; 2013 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,3-dichloro-4-nitrobenzene 210-248-3 611-06-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 1,3-dichloro-4-nitrobenzene 210-248-3 611-06-3 - View substance registered dossier
WeylChem Griesheim GmbH Stroofstr. 27 D-65933 Frankfurt am Main Germany Germany Cease Manufacture 5-chloro-2-nitrophenol 210-249-9 611-07-4 2019 View substance registered dossier
Valtris AO Belgium nv Heilig Hartlaan 21 3980 Tessenderlo Belgium Belgium Active α,2-dichlorotoluene 210-258-8 611-19-8 2017 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active α,2-dichlorotoluene 210-258-8 611-19-8 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active α,2-dichlorotoluene 210-258-8 611-19-8 - View substance registered dossier
SIPCAM OXON SPA Via Sempione, 195 20016 Pero Milano Italy Italy Active α,2-dichlorotoluene 210-258-8 611-19-8 2018 View substance registered dossier
WeylChem Höchst GmbH Brüningstr. 50 D-65929 Frankfurt am Main Germany Germany Active α,2-dichlorotoluene 210-258-8 611-19-8 - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active Salicylonitrile 210-259-3 611-20-1 2019 View substance registered dossier
KISCHEMICALS LLC Gyártelep 3792 Sajóbábony Hungary Hungary Active Salicylonitrile 210-259-3 611-20-1 2013 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid Salicylonitrile 210-259-3 611-20-1 2021 View substance registered dossier
CAFFARO INDUSTRIE S.P.A P.le Marinotti, 1 33050 Torviscosa Udine Italy Italy Active Isobutyrophenone 210-275-0 611-70-1 2012 View substance registered dossier
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark Active Isobutyrophenone 210-275-0 611-70-1 - View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active Isobutyrophenone 210-275-0 611-70-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 - View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 2021 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active L-2-hydroxy-2-phenylacetic acid 210-276-6 611-71-2 - View substance registered dossier
GRACE GmbH In der Hollerhecke 1 67545 Worms Germany Germany Active N,N-dimethylbenzamide 210-279-2 611-74-5 2018 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1,3-dimethyl-1,3-diphenylurea 210-283-4 611-92-7 2019 View substance registered dossier
Stewardship Chemicals 40 Długosza 67 43-188 Orzesze Poland Poland Active 4,4'-dihydroxybenzophenone 210-288-1 611-99-4 - View substance registered dossier
LOBA Feinchemie GmbH Fehrgasse 7 2401 Fischamend Austria Austria Active 1,2-bis(chloromethyl)benzene 210-291-8 612-12-4 - View substance registered dossier
WeylChem Höchst GmbH Brüningstr. 50 D-65929 Frankfurt am Main Germany Germany Active 1,2-bis(chloromethyl)benzene 210-291-8 612-12-4 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 2-methoxybenzyl alcohol 210-296-5 612-16-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active N-methyl-2-nitroaniline 210-303-1 612-28-2 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-[(2-aminobenzoyl)amino]benzoic acid 210-304-7 612-34-0 - View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Str. 40 30926 Seelze Deutschland Germany Germany Active 2-[(2-aminobenzoyl)amino]benzoic acid 210-304-7 612-34-0 - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active 2-[(2-aminobenzoyl)amino]benzoic acid 210-304-7 612-34-0 - View substance registered dossier
Only representative (No publishable name) - - Active 3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 - View substance registered dossier
Univar Solutions GmbH Hinsbecker Löh 10c 45257 Essen Germany Germany Active 3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium No longer Valid 3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 2013 View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 3,3'-dichlorobenzidine dihydrochloride 210-323-0 612-83-9 - View substance registered dossier
Sun Chemical B.V. Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands