Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 6,801 - 7,000 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
[(8R,9S,10R,13S,14S,17R)-3-ethoxy-17-ethynyl-13-methyl-2,7,8,9,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate	610-565-0	50717-99-2	Active	Full	Joint	≥ 1 to < 10 tonnes	18-12-2018	View substance registered dossier
4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	Active	Intermediate	Joint	Intermediate use only	24-02-2020	View substance registered dossier
2-Hydroxy-4-(trifluoromethyl)pyridine	610-554-0	50650-59-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-04-2019	View substance registered dossier
(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	Cease Manufacture	Full	Individual	Cease manufacture	21-05-2015	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	Active	Intermediate	Joint	Intermediate use only	06-05-2020	View substance registered dossier
2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt	610-522-6	503155-49-5	Active	Full	Joint	≥ 0 to < 10 tonnes	28-11-2020	View substance registered dossier
2-Propanol, 1-(3,5-dimethylphenoxy)-3-[(phenylmethyl)amino]-	610-515-8	502605-82-5	Active	Intermediate	Joint	Intermediate use only	12-10-2017	View substance registered dossier
L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester	610-513-7	502421-44-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-10-2011	View substance registered dossier
(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	Active	Intermediate	Joint	Intermediate use only	28-05-2018	View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate	610-491-9	500011-92-7	Active	Intermediate	Joint	Intermediate use only	08-10-2020	View substance registered dossier
2-(3-Chloro-2-pyridinyl)-5-oxo-3-pyrazolidinecarboxylic acid ethyl ester	610-490-3	500011-88-1	Active	Intermediate	Joint	Intermediate use only	03-12-2020	View substance registered dossier
methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	Active	Intermediate	Joint	Intermediate use only	03-05-2021	View substance registered dossier
N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	Active	Full	Joint	≥ 1 to < 10 tonnes	18-10-2021	View substance registered dossier
3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene] hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid	610-469-9	496775-61-2	Active	Intermediate	Joint	Intermediate use only	16-03-2021	View substance registered dossier
2,2-dioxo-1,2λ6-benzoxathiin-4-one	610-468-3	49670-47-5	Active	Intermediate	Joint	Intermediate use only	28-10-2016	View substance registered dossier
2-Bromo-4-fluorophenol	610-467-8	496-69-5	No longer Valid	Intermediate	Joint	No longer valid	31-07-2019	View substance registered dossier
3-(3,4-Dimethoxyphenyl)propanenitrile	610-465-7	49621-56-9	Active	Full	Joint	≥ 1 to < 10 tonnes	19-03-2018	View substance registered dossier
(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	Active	Full	Individual	≥ 1 to < 10 tonnes	23-02-2022	View substance registered dossier
4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl	610-428-5	486406-09-1	Active	Full	Joint	≥ 0 to < 10 tonnes	24-11-2022	View substance registered dossier
5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	Active	Intermediate	Joint	Intermediate use only	22-07-2020	View substance registered dossier
3-(3,4-dicyanophenylsulfonyl)propane-1-sulfonyl chloride	610-401-8	480427-96-1	No longer Valid	Intermediate	Individual	No longer valid	03-04-2017	View substance registered dossier
Iron(1+), chloro[dimethyl 9,9-dihydroxy-3-methyl-2,4-di(2-pyridinyl-kN)-7-[(2-pyridinyl-kN)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate-kN3,kN7]-, chloride	610-388-9	478945-46-9	Active	Full	Joint	≥ 1 to < 10 tonnes	02-11-2021	View substance registered dossier
1,1,2,3,3-pentamethyl-5-(2-methylprop-2-en-1-yl)octahydro-4H-inden-4-one	610-371-6	476332-63-5	Active	Intermediate	Joint	Intermediate use only	07-01-2021	View substance registered dossier
Sodium 3-hydroxy-5-sulfanyl-1,2-thiazole-4-carboxylate	610-355-9	475112-25-5	Active	Intermediate	Joint	Intermediate use only	02-10-2017	View substance registered dossier
1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	Active	Intermediate	Joint	Intermediate use only	24-05-2018	View substance registered dossier
4-[trans-4-(trans-4-butylcyclohexyl)-cyclohexyl]-1-ethoxy-2, 3-difluorobenzene	610-337-0	473257-15-7	Active	Full	Joint	≥ 1 to < 10 tonnes	14-12-2017	View substance registered dossier
2,3-Difluor-1-propoxy-4-[trans-4-(trans-4-propylcyclohexyl)- cyclohexyl]-benzene	610-336-5	473257-14-6	Active	Full	Joint	≥ 1 to < 10 tonnes	13-12-2017	View substance registered dossier
(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	Active	Intermediate	Joint	Intermediate use only	11-08-2017	View substance registered dossier
2-Amino-4,5-dimethyl-thiophene-3-carbonitrile	610-309-8	4651-94-9	Active	Intermediate	Individual	Intermediate use only	02-10-2012	View substance registered dossier
6,8-disulfanyloctanoic acid	610-288-5	462-20-4	Active	Intermediate	Joint	Intermediate use only	26-03-2021	View substance registered dossier
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
N6-Benzoyladenosine	610-251-3	4546-55-8	Active	Intermediate	Joint	Intermediate use only	10-02-2022	View substance registered dossier
3-Quinolinecarboxylic acid, 7-[6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester	610-204-7	446299-90-7	Active	Full	Joint	≥ 1 to < 10 tonnes	02-07-2021	View substance registered dossier
Boronic acid, [6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-	610-203-1	446299-81-6	Active	Full	Joint	≥ 1 to < 10 tonnes	15-12-2020	View substance registered dossier
N-(5-bromo-3-methylpyridin-2-yl)-N-methylbenzamide	610-202-6	446299-80-5	Active	Full	Joint	≥ 1 to < 10 tonnes	13-12-2022	View substance registered dossier
2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	Active	Intermediate	Joint	Intermediate use only	22-12-2022	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Individual	Intermediate use only	21-08-2018	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Joint	Intermediate use only	19-12-2022	View substance registered dossier
4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	Active	Intermediate	Joint	Intermediate use only	04-08-2020	View substance registered dossier
2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	Active	Intermediate	Joint	Intermediate use only	25-11-2021	View substance registered dossier
7-[2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)acetamido]-3-vinyl-cephem-4-carboxylic acid	610-178-7	443874-49-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-04-2018	View substance registered dossier
9H-fluorene-9,9-diyldimethanol	610-170-3	4425-93-8	Active	Intermediate	Joint	Intermediate use only	11-11-2016	View substance registered dossier
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethane-1-sulfonyl chloride	610-161-4	4403-36-5	Active	Full	Joint	≥ 1 to < 10 tonnes	14-03-2019	View substance registered dossier
2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	Active	Intermediate	Joint	Intermediate use only	30-04-2018	View substance registered dossier
triphenyl(((1r,4r)-4-((E)-prop-1-en-1-yl)cyclohexyl)methyl)phosphonium iodide	610-150-4	438193-30-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-07-2013	View substance registered dossier
4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	06-02-2013	View substance registered dossier
2,6-Difluorobenzaldehyde	610-142-0	437-81-0	Active	Intermediate	Joint	Intermediate use only	14-03-2022	View substance registered dossier
4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl) benzenesulfonic acid	610-141-5	437717-43-6	Active	Full	Individual	≥ 0 to < 10 tonnes	16-12-2013	View substance registered dossier
amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	Active	Full	Joint	≥ 10 000 to < 100 000 tonnes	26-04-2023	View substance registered dossier
[(2S,3R,5S)-3-acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate	610-122-1	433733-94-9	No longer Valid	Full	Joint	No longer valid	14-01-2020	View substance registered dossier
2-[benzyl-[1-(4-methoxyphenyl)propan-2-yl]amino]-1-(3-nitro-4-phenylmethoxyphenyl)ethanone	610-116-9	43229-66-9	Active	Intermediate	Joint	Intermediate use only	09-07-2019	View substance registered dossier
6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	Active	Intermediate	Joint	Intermediate use only	09-07-2019	View substance registered dossier
6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	Active	Intermediate	Joint	Intermediate use only	16-07-2020	View substance registered dossier
(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	Active	Intermediate	Joint	Intermediate use only	13-10-2021	View substance registered dossier
5’,5’’’’-(1,1,1-trifluoropropane-2,2-diyl)bis(1,1’:3’,1’’-terphenyl-2’-ol)	610-104-3	43100-47-6	Active	Full	Joint	≥ 1 to < 10 tonnes	26-11-2015	View substance registered dossier
Benzenesulfonic acid, 2-amino-5-((2-(sulfooxy)ethyl)sulfonyl)-	610-097-7	42986-22-1	Active	Intermediate	Joint	Intermediate use only	22-03-2019	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	11-06-2020	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	10-10-2016	View substance registered dossier
1-Naphthalenemethanamine, a-methyl-	610-076-2	42882-31-5	Active	Intermediate	Joint	Intermediate use only	10-01-2018	View substance registered dossier
6-Bromo-1-hexanol	610-072-0	4286-55-9	Active	Intermediate	Individual	Intermediate use only	02-05-2016	View substance registered dossier
2,7-dihydroxyfluoren-9-one	610-035-9	42523-29-5	Active	Intermediate	Joint	Intermediate use only	03-07-2018	View substance registered dossier
2-methylprop-1-ene, pentamer	610-010-2	42278-27-3	Active	Intermediate	Joint	Intermediate use only	21-01-2022	View substance registered dossier
Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-	610-008-1	42267-27-6	Active	Intermediate	Joint	Intermediate use only	13-04-2018	View substance registered dossier
(3aS,9aS,9bS)-3-hydroxy-3a-methyl-6-(3-oxobutyl)-1,2,3,3a,4,5,8,9,9a,9b-decahydro-7H-cyclopenta[a]naphthalen-7-one	609-999-3	4222-76-8	Active	Intermediate	Joint	Intermediate use only	07-02-2022	View substance registered dossier
2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	Active	Intermediate	Joint	Intermediate use only	15-05-2023	View substance registered dossier
(3-chloro-4-methoxyphenyl)methanaminium chloride	609-972-6	41965-95-1	Active	Intermediate	Joint	Intermediate use only	13-09-2017	View substance registered dossier
(3-chloro-4-methoxyphenyl)methanaminium chloride	609-972-6	41965-95-1	Active	Intermediate	Individual	Intermediate use only	21-01-2014	View substance registered dossier
(S)-1-(4-Methoxyphenyl)ethylamine	609-962-1	41851-59-6	Active	Intermediate	Joint	Intermediate use only	22-10-2012	View substance registered dossier
1-nitro-2-phenylsulfanylbenzene	609-953-2	4171-83-9	Active	Intermediate	Joint	Intermediate use only	20-02-2020	View substance registered dossier
Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside	609-920-2	4137-56-8	Active	Intermediate	Joint	Intermediate use only	06-07-2020	View substance registered dossier
1 alpha-Methyl-4-androstene-3,17-dione	609-915-5	4136-62-3	Active	Intermediate	Individual	Intermediate use only	03-12-2015	View substance registered dossier
4-(Methylamino)-3-nitrobenzoic acid	609-904-5	41263-74-5	Active	Intermediate	Joint	Intermediate use only	29-11-2019	View substance registered dossier
1-(2,3-dichlorophenyl)piperazine	609-896-3	41202-77-1	Active	Intermediate	Individual	Intermediate use only	26-02-2015	View substance registered dossier
1-(2,3-dichlorophenyl)piperazine	609-896-3	41202-77-1	Active	Intermediate	Individual	Intermediate use only	10-03-2011	View substance registered dossier
methyl (E)-3-methyl-4-oxo-but-2-enoate	609-870-1	40835-18-5	Active	Intermediate	Joint	Intermediate use only	20-02-2017	View substance registered dossier
5-hydroxy-4-methyl-2,5-dihydrofuran-2-one	609-869-6	40834-42-2	Active	Intermediate	Joint	Intermediate use only	25-08-2016	View substance registered dossier
2-ethyl-2-(3-methoxyphenyl)-butanenitrile	609-861-2	40692-21-5	Active	Intermediate	Joint	Intermediate use only	02-08-2018	View substance registered dossier
6-methyl-4-phenyl-3,4-dihydrochromen-2-one	609-846-0	40546-94-9	Active	Intermediate	Joint	Intermediate use only	20-11-2021	View substance registered dossier
benzyl (3,14,25-trihydroxy-2,10,13,21,24-pentaoxo-3,9,14,20,25-pentaazatriacontan-30-yl)carbamate	609-812-5	402913-84-2	Active	Intermediate	Individual	Intermediate use only	25-10-2012	View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride	609-806-2	4025-75-6	Active	Intermediate	Individual	Intermediate use only	18-12-2019	View substance registered dossier
Diphenylmethyl (6R,7R)-8-oxo-7-[(phenylacetyl)amino]-3-{[4-(pyridin-4-yl)-1,3-thiazol-2-yl]thio}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	609-782-3	400827-68-1	Active	Intermediate	Joint	Intermediate use only	07-10-2019	View substance registered dossier
2-Chlorobenzoylacetonitrile	609-772-9	40018-25-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	17-08-2015	View substance registered dossier
21-Hydroxy-16 alpha-methyl-4-pregnene-3,20-dione	609-766-6	39987-86-5	Active	Intermediate	Individual	Intermediate use only	27-08-2018	View substance registered dossier
21-Acetoxy-16 alpha-methyl-4-pregnene-3,20-dione	609-765-0	39987-85-4	Active	Intermediate	Individual	Intermediate use only	11-03-2016	View substance registered dossier
(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid	609-759-8	39961-95-0	Active	Intermediate	Joint	Intermediate use only	29-01-2018	View substance registered dossier
1H-1,2,4-Triazole-3-carboxylic acid, 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-, methyl ester	609-754-0	39925-10-5	Active	Intermediate	Joint	Intermediate use only	08-05-2019	View substance registered dossier
5-bromo-2-nitropyridine	609-748-8	39856-50-3	Active	Intermediate	Individual	Intermediate use only	03-09-2015	View substance registered dossier
5-bromo-2-nitropyridine	609-748-8	39856-50-3	Active	Intermediate	Joint	Intermediate use only	28-08-2018	View substance registered dossier
5-(1-methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol	609-737-8	3967-32-6	Active	Intermediate	Joint	Intermediate use only	10-02-2017	View substance registered dossier
(9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione	609-736-2	39672-75-8	Active	Intermediate	Individual	Intermediate use only	30-05-2014	View substance registered dossier
(R)-(-)-1,1'-Binaphthalene-2,2'-diyl hydrogen phosphate	609-734-1	39648-67-4	Active	Intermediate	Joint	Intermediate use only	07-04-2020	View substance registered dossier
6-chloro-N,N,N',N'-tetrabutyl-1,3,5-triazine-2,4-diamine	609-724-7	39605-45-3	Active	Intermediate	Joint	Intermediate use only	11-04-2023	View substance registered dossier
1,1-Bis(hydroxymethyl)cyclopropane	609-723-1	39590-81-3	Active	Intermediate	Joint	Intermediate use only	28-06-2016	View substance registered dossier
ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate	609-702-7	395068-96-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	04-09-2017	View substance registered dossier
ethyl 2-amino-3-cyclobutylpropanoate	609-695-0	394735-17-2	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-12-2012	View substance registered dossier
2-phenoxyethanol; phosphoric acid	609-691-9	39464-70-5	Active	Full	Joint	≥ 1 to < 10 tonnes	29-10-2018	View substance registered dossier
5-Fluoro-2-nitrobenzoic acid methyl ester	609-664-1	393-85-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-08-2014	View substance registered dossier
2,4-Dichloro-5-(trifluoromethyl)pyrimidine	609-648-4	3932-97-6	Active	Intermediate	Individual	Intermediate use only	07-10-2014	View substance registered dossier
2-chloro-N-(2,4,6-trimethylphenyl)acetamide	609-612-8	3910-51-8	Active	Intermediate	Individual	Intermediate use only	21-05-2013	View substance registered dossier
1,3-bis(isocyanatomethyl)cyclohexane	609-567-4	38661-72-2	Active	Full	Joint	≥ 10 to < 100 tonnes	13-07-2020	View substance registered dossier
2,6-Dichloropyridine-3-carboxylic acid	609-561-1	38496-18-3	Active	Intermediate	Individual	Intermediate use only	15-01-2019	View substance registered dossier
2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	Active	Intermediate	Joint	Intermediate use only	16-08-2021	View substance registered dossier
2-((6,6-diméthylbicyclo[3.1.1]hept-2-yl)éthoxy)éthyl morpholine	609-541-2	38284-47-8	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
2-[difluoro(methoxy)methyl]-1,1,1,3,3,3-hexafluoropropane	609-534-4	382-26-3	Active	Intermediate	Individual	Intermediate use only	19-03-2019	View substance registered dossier
Reaction product of 2-Propyn-1-ol with methyloxirane	609-530-2	38172-91-7	Active	Full	Joint	≥ 100 to < 1 000 tonnes	03-08-2018	View substance registered dossier
ethyl 3-amino-2-cyanoprop-2-enoate	609-521-3	38109-77-2	Active	Intermediate	Individual	Intermediate use only	14-05-2013	View substance registered dossier
8-Chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5Hbenzo[5,6]cyclohepta[1,2-b]pyridin-11-ol	609-518-7	38089-93-9	Active	Intermediate	Joint	Intermediate use only	30-08-2017	View substance registered dossier
(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid	609-516-6	38075-43-3	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-01-2018	View substance registered dossier
Glycine, N-acetyl-N-[3-(trifluoromethyl)phenyl]valyl-, ethyl ester	609-496-9	379685-94-6	Active	Full	Joint	≥ 1 to < 10 tonnes	06-04-2018	View substance registered dossier
1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1)	609-494-8	37951-53-4	Active	Intermediate	Joint	Intermediate use only	31-08-2018	View substance registered dossier
6-fluoro-2-methylindan-1-one	609-478-0	37794-19-7	Active	Intermediate	Joint	Intermediate use only	02-05-2017	View substance registered dossier
Benzenamine, 2-[(4-chlorophenyl)thio]-	609-474-9	37750-29-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-10-2012	View substance registered dossier
2,3-dimethyl-4-nitro-1-oxidopyridin-1-ium	609-469-1	37699-43-7	Active	Intermediate	Joint	Intermediate use only	11-03-2022	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
benzhydryl (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-trityloxyiminoacetyl]amino]-3-formyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	609-462-3	376653-37-1	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
2-Propenoic acid, 2-cyano-3-(3,4-dimethoxyphenyl)-, (2E)-	609-453-4	37630-52-7	Active	Full	Joint	≥ 1 to < 10 tonnes	15-06-2018	View substance registered dossier
1,1,1-trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide	609-445-0	37595-74-7	Active	Intermediate	Joint	Intermediate use only	17-05-2021	View substance registered dossier
6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (6E)-	609-442-4	375846-25-6	Active	Intermediate	Joint	Intermediate use only	13-02-2018	View substance registered dossier
4-[(4,6-dihydroxypyrimidin-2-yl)amino]benzonitrile	609-425-1	374067-80-8	Cease Manufacture	Full	Joint	Cease manufacture	05-12-2017	View substance registered dossier
myo-inositol-hexakisphosphate 3-phosphohydrolase	609-386-0	37288-11-2	Active	Full	Joint	≥ 0 to < 10 tonnes	22-11-2018	View substance registered dossier
Chloromethylene dimethylammonium chloride	609-368-2	3724-43-4	No longer Valid	Intermediate	Individual	No longer valid	12-11-2010	View substance registered dossier
N-(2-methylsulfinyl-1,1-dimethyl-ethyl)-N'-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide	609-338-9	371771-07-2	Active	Intermediate	Joint	Intermediate use only	07-11-2013	View substance registered dossier
Hexasodium 2,2´-[vinylenebis[(3-sulphonato-4,1-phenylene)imino[6-[bis(2-hydroxypropyl)amino]-1,3,5-triazine-4,2-diyl]imino]]bis(benzene-1,4-disulphonate)	609-336-8	371756-75-1	Active	Full	Joint	≥ 100 to < 1 000 tonnes	15-03-2012	View substance registered dossier
N,N-dimethyl-1-adamantanamine	609-335-2	3717-40-6	Active	Intermediate	Joint	Intermediate use only	06-08-2018	View substance registered dossier
Reaction mass of (R)-(-)-1-methoxy-2-propylamine and (S)-(+)-1-methoxy-2-propylamine	609-333-1	37143-54-7	Active	Intermediate	Individual	Intermediate use only	28-10-2020	View substance registered dossier
1-Ethyl-3-methylimidazolium dicyanamide	609-330-5	370865-89-7	Active	Full	Joint	≥ 100 to < 1 000 tonnes	17-09-2021	View substance registered dossier
Methanone, [5-chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)phenyl]phenyl-	609-311-1	36916-19-5	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
6,10,14-Trimethyl-5-Pentadecen-2-on	609-306-4	3689-69-8	Active	Intermediate	Joint	Intermediate use only	16-03-2018	View substance registered dossier
2-{[(4-Chloro-3-methoxypyridin-2-yl)methyl]sulfanyl)-6-(difluoromethoxy)-1H-benzimidazole	609-304-3	368890-20-4	Active	Intermediate	Individual	Intermediate use only	14-02-2011	View substance registered dossier
2-{[(4-Chloro-3-methoxypyridin-2-yl)methyl]sulfanyl)-6-(difluoromethoxy)-1H-benzimidazole	609-304-3	368890-20-4	Active	Intermediate	Individual	Intermediate use only	17-02-2010	View substance registered dossier
(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide	609-299-8	368421-58-3	Active	Intermediate	Individual	Intermediate use only	16-10-2017	View substance registered dossier
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid hydrochloride	609-287-2	36760-44-8	Active	Intermediate	Joint	Intermediate use only	13-01-2015	View substance registered dossier
4-(chlorocarbonyl)phenyl 3-chloropropanoate	609-280-4	366448-53-5	Active	Intermediate	Joint	Intermediate use only	30-10-2020	View substance registered dossier
4-[(3-chloropropanoyl)oxy]benzoic acid	609-278-3	366448-45-5	Active	Intermediate	Joint	Intermediate use only	30-10-2020	View substance registered dossier
Sodium (4-nitrophenyl)methanesulfonate	609-277-8	36639-50-6	Active	Intermediate	Individual	Intermediate use only	18-12-2019	View substance registered dossier
1,4-Benzodioxane-2-carboxylic acid	609-276-2	3663-80-7	No longer Valid	Full	Joint	No longer valid	22-07-2019	View substance registered dossier
2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	Active	Full	Joint	≥ 10 to < 100 tonnes	04-04-2022	View substance registered dossier
phosphoramidic dichloride, methyl-	609-264-7	36598-86-4	Active	Intermediate	Joint	Intermediate use only	22-05-2018	View substance registered dossier
disodium butane-1,4-disulfonate	609-262-6	36589-61-4	Active	Intermediate	Individual	Intermediate use only	19-01-2011	View substance registered dossier
2,5-dimethyl-4-[2-methylsulfonyl-4-(trifluoromethyl)benzoyl]-1H-pyrazol-3-one	609-256-3	365400-11-9	Active	Full	Joint	≥ 10 to < 100 tonnes	04-04-2023	View substance registered dossier
3-Methoxy-18-methyl-1,3,5(10)-estratrien-17 beta-ol	609-222-8	3625-82-9	Active	Intermediate	Individual	Intermediate use only	01-09-2022	View substance registered dossier
3,7,11-Trimethyldodec-1-en-3-ol	609-221-2	3625-46-5	Active	Intermediate	Joint	Intermediate use only	14-03-2018	View substance registered dossier
tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate	609-213-9	361440-67-7	Active	Intermediate	Individual	Intermediate use only	20-03-2017	View substance registered dossier
ethyl 1-[2-(2,4-dichlorophenyl)acetoxy]cyclohexanecarboxylate	609-206-0	361366-16-7	Active	Intermediate	Individual	Intermediate use only	25-09-2012	View substance registered dossier
ethyl 1-(2-mesitylacetoxy)cyclopentanecarboxylate	609-205-5	361366-15-6	Active	Intermediate	Individual	Intermediate use only	14-09-2012	View substance registered dossier
6 alpha-Fluoro-11 beta-hydroxy-16 alpha-methyl-21-valeryloxy-1,4-pregnadiene-3,20-dione	609-203-4	36130-02-6	Active	Full	Joint	≥ 0 to < 10 tonnes	20-05-2022	View substance registered dossier
3,5-Heptamedopme. 1,7-bis(hydroxy-3methoxyphenyl)heptane	609-201-3	36062-04-1	Active	Full	Individual	≥ 1 to < 10 tonnes	18-06-2014	View substance registered dossier
Phosphoric acid, mono(2-aminoethyl) mono(2,3-dihydroxypropyl) ester, monohydrate, (R)-	609-192-6	35907-34-7	Active	Full	Joint	≥ 1 to < 10 tonnes	28-11-2018	View substance registered dossier
1-(3-allyl-2-hydroxyphenyl)propan-1-one	609-190-5	35888-91-6	Active	Intermediate	Joint	Intermediate use only	20-04-2016	View substance registered dossier
5,6-Dihydro-2-[trans,trans-4'-propyl(1,1'-bicyclohexyl-4-yl)-4H-1,3-dithiin-1-iumtrifluoromethanesulfonate	609-186-3	358732-12-4	Active	Intermediate	Joint	Intermediate use only	24-11-2022	View substance registered dossier
1H,5H-Pyrazolo[1,2-a]pyrazol-1-one, 3-amino-6,7-dihydro-, hydrochloride (1:1)	609-180-0	358360-19-7	Active	Intermediate	Joint	Intermediate use only	03-09-2018	View substance registered dossier
1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one	609-173-2	3575-80-2	Active	Intermediate	Joint	Intermediate use only	04-12-2017	View substance registered dossier
1,3,4,5-tetrahydro-2H-1,5-methano-3-benzazepin-2-one	609-171-1	357426-13-2	Active	Intermediate	Joint	Intermediate use only	24-05-2018	View substance registered dossier
tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	Active	Intermediate	Joint	Intermediate use only	13-03-2020	View substance registered dossier
2,5-bis(2,2,2-trifluoroethoxy)benzoic acid	609-132-9	35480-52-5	Active	Intermediate	Individual	Intermediate use only	21-02-2012	View substance registered dossier
Phosphonium, (3-methyl-4-oxo-2-butenyl)triphenyl-, chloride	609-124-5	3541-81-9	Active	Intermediate	Joint	Intermediate use only	03-09-2020	View substance registered dossier
methyl 10-methoxy-5H-dibenzo[b,f]azepine-5-carboxylate	609-118-2	353497-37-7	No longer Valid	Intermediate	Individual	No longer valid	15-03-2012	View substance registered dossier
Acetic acid, 2-hydroxy-, ammonium salt (1:1)	609-106-7	35249-89-9	Active	Full	Individual	≥ 1 to < 10 tonnes	22-05-2014	View substance registered dossier
3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile	609-105-1	35249-62-8	Active	Full	Joint	≥ 1 to < 10 tonnes	18-09-2018	View substance registered dossier
Boronic acid, B-(2-fluoro-3-methoxyphenyl)-	609-099-0	352303-67-4	Active	Intermediate	Joint	Intermediate use only	12-01-2021	View substance registered dossier
10-[4-(2-chloroethyl)piperazin-1-yl]-2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaene	609-095-9	352232-17-8	Active	Intermediate	Joint	Intermediate use only	28-03-2018	View substance registered dossier
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile	609-091-7	35202-54-1	Active	Full	Joint	≥ 1 to < 10 tonnes	19-09-2018	View substance registered dossier
3-Amino-1-(2-chlorophenyl)-1-phenylpropan-1-ol	609-081-2	35173-30-9	Active	Intermediate	Joint	Intermediate use only	16-07-2018	View substance registered dossier
Phosphinic acid, diethyl-, sodium salt	609-080-7	35160-38-4	Active	Full	Joint	≥ 1 to < 10 tonnes	02-08-2017	View substance registered dossier
(Z)-dodec-9-en-1-ol	609-079-1	35148-18-6	Active	Intermediate	Individual	Intermediate use only	04-09-2019	View substance registered dossier
2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	Active	Full	Joint	≥ 1 to < 10 tonnes	20-07-2018	View substance registered dossier
2-hydroxy-N,N-dimethyl-propanamide	609-066-0	35123-06-9	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	17-03-2023	View substance registered dossier
1-(ethoxymethoxy)-4-methyl-benzene	609-065-5	35117-05-6	Active	Intermediate	Joint	Intermediate use only	24-10-2022	View substance registered dossier
1-(ethoxymethoxy)-4-methyl-benzene	609-065-5	35117-05-6	Active	Intermediate	Individual	Intermediate use only	26-04-2019	View substance registered dossier
2-ISOPROPYL-1,3-DIOXANE-5,5-DICARBOXYLIC ACID DIETHYL ESTER	609-063-4	35113-48-5	Active	Intermediate	Joint	Intermediate use only	06-05-2013	View substance registered dossier
potassium (2S)-2-{[(2Z)-4-ethoxy-4-oxobut-2-en-2-yl]amino}propanoate	609-057-1	35052-92-7	Active	Intermediate	Joint	Intermediate use only	02-06-2022	View substance registered dossier
2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate	609-054-5	35011-47-3	Active	Intermediate	Joint	Intermediate use only	21-02-2018	View substance registered dossier
(2-(tert-butoxy)-2-oxoethyl)triphenylphosphonium chloride	609-051-9	35000-37-4	Active	Intermediate	Joint	Intermediate use only	08-12-2015	View substance registered dossier
2-(dimethylamino)ethyl dodecanoate	609-033-0	34839-10-6	Active	Full	Joint	≥ 1 to < 10 tonnes	05-11-2019	View substance registered dossier
2-(diphenylphosphino)benzonitrile	609-030-4	34825-99-5	No longer Valid	Intermediate	Individual	No longer valid	21-12-2017	View substance registered dossier
Ethyl [10-(3-chloropropanoyl)-10H-phenothiazin-2-yl]carbamate	609-026-2	34749-22-9	Active	Intermediate	Joint	Intermediate use only	13-12-2017	View substance registered dossier
(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride	609-015-2	3464-71-9	Active	Intermediate	Joint	Intermediate use only	12-03-2018	View substance registered dossier
N-[3-(dimethylamino)propyl]-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octane-1-sulfonamide	608-993-8	34455-22-6	Active	Intermediate	Joint	Intermediate use only	15-05-2013	View substance registered dossier
4-Propionylcyclohexylbenzol	608-991-7	344348-40-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	11-12-2012	View substance registered dossier
(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID	608-945-6	340-90-9	Active	Full	Joint	≥ 10 to < 100 tonnes	21-02-2023	View substance registered dossier
1H-benzo[10,5]anthra[2,1,9-def]isoquinoline-1,3(2H)-dione	608-929-9	33955-44-1	Active	Intermediate	Individual	Intermediate use only	01-12-2014	View substance registered dossier
3-[(4-Fluorophenyl)thio]-2-hydroxy-2-methylpropanoic acid	608-927-8	339530-91-5	Active	Intermediate	Individual	Intermediate use only	21-08-2014	View substance registered dossier
5H-Dibenz[b,f]azepine-5-carbonyl chloride	608-925-7	33948-22-0	Active	Intermediate	Individual	Intermediate use only	31-05-2018	View substance registered dossier
Methyl-6-bromo-2-naphthoate	608-896-0	33626-98-1	Active	Intermediate	Joint	Intermediate use only	02-08-2022	View substance registered dossier
cyclobutane-1,1-dicarboxamide	608-895-5	33582-68-2	Active	Intermediate	Joint	Intermediate use only	19-03-2019	View substance registered dossier
trimethoxy(3-methoxypropyl)silane	608-893-4	33580-59-5	Active	Intermediate	Joint	Intermediate use only	14-09-2022	View substance registered dossier
O-(4-Nitrophenyl)hydroxylamine	608-888-7	33543-55-4	Active	Intermediate	Joint	Intermediate use only	24-05-2018	View substance registered dossier
2-(2-Formyl-4-nitrophenoxy)hexanoic acid	608-880-3	335153-21-4	No longer Valid	Intermediate	Individual	No longer valid	08-09-2010	View substance registered dossier
Di-tert-butyl phosphate	608-874-0	33494-81-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	01-03-2016	View substance registered dossier
(R)-(-)-3-Aminopiperidine dihydrochloride	608-870-9	334618-23-4	Active	Intermediate	Joint	Intermediate use only	09-05-2018	View substance registered dossier
1-(diphenylmethyl)azetidin-3-yl methanesulfonate	608-857-8	33301-41-6	Active	Intermediate	Individual	Intermediate use only	25-08-2021	View substance registered dossier
(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile	608-856-2	33300-19-5	Active	Intermediate	Joint	Intermediate use only	19-06-2018	View substance registered dossier
2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-	608-855-7	33288-71-0	Active	Intermediate	Joint	Intermediate use only	09-05-2018	View substance registered dossier
2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-	608-855-7	33288-71-0	Cease Manufacture	Full	Joint	Cease manufacture	29-05-2018	View substance registered dossier
Benzeneacetic acid, 3-ethoxy-4-(ethoxycarbonyl)-, ethyl ester	608-847-3	332347-69-0	Active	Intermediate	Joint	Intermediate use only	09-07-2018	View substance registered dossier
(S)-2-aminopropanamide hydrochloride	608-843-1	33208-99-0	Active	Intermediate	Joint	Intermediate use only	20-01-2017	View substance registered dossier
Methyl (Z)-2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)-2-((trityloxy)imino) acetate	608-838-4	331780-39-3	Active	Intermediate	Joint	Intermediate use only	22-03-2023	View substance registered dossier
sodium;2-chloroprop-2-enoate;hydrate	608-818-5	32997-86-7	Active	Full	Joint	≥ 1 to < 10 tonnes	24-05-2019	View substance registered dossier
(4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate	608-799-3	329181-36-4	Active	Intermediate	Individual	Intermediate use only	10-06-2009	View substance registered dossier

Showing 6,801 - 7,000 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Active	[(8R,9S,10R,13S,14S,17R)-3-ethoxy-17-ethynyl-13-methyl-2,7,8,9,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate	610-565-0	50717-99-2	2018	View substance registered dossier
Clariant Produkte (Deutschland) GmbH	August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany	Germany	Active	4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	-	View substance registered dossier
[Confidential]	-	-	-	4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	-	View substance registered dossier
CSI-OR47DUB	Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland	Ireland	Cease Manufacture	2-Hydroxy-4-(trifluoromethyl)pyridine	610-554-0	50650-59-4	2023	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	2019	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	2020	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt	610-522-6	503155-49-5	2020	View substance registered dossier
Corden Pharma Bergamo S.p.A.	Via Bergamo, 121 IT-24047 Treviglio BG Italy	Italy	Active	2-Propanol, 1-(3,5-dimethylphenoxy)-3-[(phenylmethyl)amino]-	610-515-8	502605-82-5	-	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Cease Manufacture	L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester	610-513-7	502421-44-5	2022	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	-	View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company	Little Island County NA Cork Ireland	Ireland	Active	(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	-	View substance registered dossier
[Confidential]	-	-	-	Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate	610-491-9	500011-92-7	-	View substance registered dossier
[Confidential]	-	-	-	2-(3-Chloro-2-pyridinyl)-5-oxo-3-pyrazolidinecarboxylic acid ethyl ester	610-490-3	500011-88-1	-	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	2021	View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH	Riedstrasse 2 89555 Steinheim Germany	Germany	Active	N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	-	View substance registered dossier
CIBA VISION GmbH	Industriering1 63868 Großwallstadt Bavaria Germany	Germany	Active	N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	2021	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene] hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid	610-469-9	496775-61-2	2021	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2,2-dioxo-1,2λ6-benzoxathiin-4-one	610-468-3	49670-47-5	-	View substance registered dossier
Wychem Limited	Bury Road CB8 8YN Stradishall Suffolk United Kingdom	United Kingdom	No longer Valid	2-Bromo-4-fluorophenol	610-467-8	496-69-5	2021	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	3-(3,4-Dimethoxyphenyl)propanenitrile	610-465-7	49621-56-9	-	View substance registered dossier
Isobionics B.V.	Urmonderbaan 22 6167 RD Geleen Netherlands	Netherlands	Active	(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl	610-428-5	486406-09-1	2022	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	2020	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	-	View substance registered dossier
Fujifilm Imaging Colorants Limited	Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom	United Kingdom	No longer Valid	3-(3,4-dicyanophenylsulfonyl)propane-1-sulfonyl chloride	610-401-8	480427-96-1	2021	View substance registered dossier
WeylChem Lamotte S.A.S	Rue du Flottage B.P. 1 60350 Trosly Breuil France	France	Active	Iron(1+), chloro[dimethyl 9,9-dihydroxy-3-methyl-2,4-di(2-pyridinyl-kN)-7-[(2-pyridinyl-kN)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate-kN3,kN7]-, chloride	610-388-9	478945-46-9	2018; 2021	View substance registered dossier
IFF Benicarlo, S.L.	Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain	Spain	Active	1,1,2,3,3-pentamethyl-5-(2-methylprop-2-en-1-yl)octahydro-4H-inden-4-one	610-371-6	476332-63-5	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	Sodium 3-hydroxy-5-sulfanyl-1,2-thiazole-4-carboxylate	610-355-9	475112-25-5	-	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Active	1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-[trans-4-(trans-4-butylcyclohexyl)-cyclohexyl]-1-ethoxy-2, 3-difluorobenzene	610-337-0	473257-15-7	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	2,3-Difluor-1-propoxy-4-[trans-4-(trans-4-propylcyclohexyl)- cyclohexyl]-benzene	610-336-5	473257-14-6	-	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Active	(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	2017	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	2-Amino-4,5-dimethyl-thiophene-3-carbonitrile	610-309-8	4651-94-9	2012	View substance registered dossier
Alzchem Trostberg GmbH	Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany	Germany	Active	6,8-disulfanyloctanoic acid	610-288-5	462-20-4	2021	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	2018	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	N6-Benzoyladenosine	610-251-3	4546-55-8	2022	View substance registered dossier
Biosynth s.r.o.	Nobelova 34 83605 Bratislava Slovakia	Slovakia	Active	N6-Benzoyladenosine	610-251-3	4546-55-8	-	View substance registered dossier
[Confidential]	-	-	-	3-Quinolinecarboxylic acid, 7-[6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester	610-204-7	446299-90-7	-	View substance registered dossier
[Confidential]	-	-	-	Boronic acid, [6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-	610-203-1	446299-81-6	-	View substance registered dossier
[Confidential]	-	-	-	N-(5-bromo-3-methylpyridin-2-yl)-N-methylbenzamide	610-202-6	446299-80-5	-	View substance registered dossier
Medichem S.A.	Polígon Industrial de Celrà 17460 Celrà Girona Spain	Spain	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	2012; 2018; 2020; 2022	View substance registered dossier
Medichem Manufacturing (Malta) Limited	HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta	Malta	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018; 2022	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	7-[2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)acetamido]-3-vinyl-cephem-4-carboxylic acid	610-178-7	443874-49-5	2021	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	9H-fluorene-9,9-diyldimethanol	610-170-3	4425-93-8	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethane-1-sulfonyl chloride	610-161-4	4403-36-5	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	triphenyl(((1r,4r)-4-((E)-prop-1-en-1-yl)cyclohexyl)methyl)phosphonium iodide	610-150-4	438193-30-7	2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	2022	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	2,6-Difluorobenzaldehyde	610-142-0	437-81-0	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl) benzenesulfonic acid	610-141-5	437717-43-6	-	View substance registered dossier
Thermal Ceramics de France S.A.S.	3, Rue du 18 Juin 1827 42160 Andrezieux-Boutheon France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2014; 2015; 2016; 2019; 2020; 2021	View substance registered dossier
WSP Deutschland A.G. (OR12)	Dingolfinger Straße 1-15 81673 Munchen Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
KCC Europe GmbH	Hansaring 61 50670 Köln Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Nutec Europe, S.L.	Eitua Industrialdea 71 A 48240 Berriz Spain	Spain	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Thermal Ceramics de France S.A.S.	3 rue du 18 Juin 1827 42160 Andrezieux-Boutheon France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Meca-Trade OY	Mikkolantie 32 FIN-28130 Pori Finland	Finland	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
IIP Europe GmbH	Fritz-Vomfelde-Str.34 40547 Duesseldorf Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Vulcor Insulation BV(Hubei SOLI New Materials Technology Co. , Ltd)	Wanraaij 4 6673 DN Andelst Netherlands	Netherlands	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2023	View substance registered dossier
Thermal Ceramics UK Ltd	Tebay Road CH62 3PH Bromborough Wirral United Kingdom	United Kingdom	No longer Valid	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2021	View substance registered dossier
Unifrax France	Mill Lane, Rainford Lorette Wa118LP St Helens, merseyside, France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2010; 2021	View substance registered dossier
Unifrax France 001	17 Rue Antoine Durafour Lorette 42420 Lorette France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2010	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	[(2S,3R,5S)-3-acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate	610-122-1	433733-94-9	2021	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	2-[benzyl-[1-(4-methoxyphenyl)propan-2-yl]amino]-1-(3-nitro-4-phenylmethoxyphenyl)ethanone	610-116-9	43229-66-9	2018; 2019	View substance registered dossier
JSC Grindeks	53 Krustpils St LV 1057 Riga Latvia	Latvia	Active	6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	2017; 2019	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	-	View substance registered dossier
EUROAPI Hungary Ltd.	Tó utca 1-5. 1045 Budapest Hungary	Hungary	Active	(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	-	View substance registered dossier
SONEAS Chemicals Ltd.	Banyaleg Str. 47-59. H-1225 Budapest Hungary	Hungary	Active	(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	2020	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	5’,5’’’’-(1,1,1-trifluoropropane-2,2-diyl)bis(1,1’:3’,1’’-terphenyl-2’-ol)	610-104-3	43100-47-6	-	View substance registered dossier
BLENDWELL SA	rue Benoît, 50 Zoning Industriel B-7370 Dour Belgium	Belgium	Active	Benzenesulfonic acid, 2-amino-5-((2-(sulfooxy)ethyl)sulfonyl)-	610-097-7	42986-22-1	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
Výzkumný ústav organických syntéz a.s.	č.p. 296 533 54 Rybitví Czech Republic	Czech Republic	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	1-Naphthalenemethanamine, a-methyl-	610-076-2	42882-31-5	-	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	6-Bromo-1-hexanol	610-072-0	4286-55-9	-	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2,7-dihydroxyfluoren-9-one	610-035-9	42523-29-5	2018	View substance registered dossier
INEOS Manufacturing Deutschland GmbH	Alte Strasse 201 50769 Koeln Germany	Germany	Active	2-methylprop-1-ene, pentamer	610-010-2	42278-27-3	2020; 2022	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-	610-008-1	42267-27-6	-	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(3aS,9aS,9bS)-3-hydroxy-3a-methyl-6-(3-oxobutyl)-1,2,3,3a,4,5,8,9,9a,9b-decahydro-7H-cyclopenta[a]naphthalen-7-one	609-999-3	4222-76-8	2022	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2023	View substance registered dossier
WeylChem Höchst GmbH	Brüningstr. 50 D-65929 Frankfurt am Main Germany	Germany	Active	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2023	View substance registered dossier
WeylChem Griesheim GmbH	Stroofstr. 27 D-65933 Frankfurt am Main Germany	Germany	Cease Manufacture	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2019	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(3-chloro-4-methoxyphenyl)methanaminium chloride	609-972-6	41965-95-1	-	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	(3-chloro-4-methoxyphenyl)methanaminium chloride	609-972-6	41965-95-1	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(S)-1-(4-Methoxyphenyl)ethylamine	609-962-1	41851-59-6	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	1-nitro-2-phenylsulfanylbenzene	609-953-2	4171-83-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside	609-920-2	4137-56-8	-	View substance registered dossier
Roche Ireland Limited	Clarehill . Clarecastle Ireland	Ireland	Active	Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside	609-920-2	4137-56-8	2018; 2020	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	1 alpha-Methyl-4-androstene-3,17-dione	609-915-5	4136-62-3	-	View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U.	Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain	Spain	Active	4-(Methylamino)-3-nitrobenzoic acid	609-904-5	41263-74-5	2019	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	4-(Methylamino)-3-nitrobenzoic acid	609-904-5	41263-74-5	2019	View substance registered dossier
Chemsafe	Via Ribes 5 10010 Colleretto Giacosa (TO) Italy	Italy	Active	1-(2,3-dichlorophenyl)piperazine	609-896-3	41202-77-1	-	View substance registered dossier
SYNTESIA CHEMIE GmbH	Martinistr. 13 20251 Hamburg Germany	Germany	Active	1-(2,3-dichlorophenyl)piperazine	609-896-3	41202-77-1	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	methyl (E)-3-methyl-4-oxo-but-2-enoate	609-870-1	40835-18-5	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	5-hydroxy-4-methyl-2,5-dihydrofuran-2-one	609-869-6	40834-42-2	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	5-hydroxy-4-methyl-2,5-dihydrofuran-2-one	609-869-6	40834-42-2	2016	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	2-ethyl-2-(3-methoxyphenyl)-butanenitrile	609-861-2	40692-21-5	2018	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	6-methyl-4-phenyl-3,4-dihydrochromen-2-one	609-846-0	40546-94-9	-	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	6-methyl-4-phenyl-3,4-dihydrochromen-2-one	609-846-0	40546-94-9	2019; 2020; 2021	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	benzyl (3,14,25-trihydroxy-2,10,13,21,24-pentaoxo-3,9,14,20,25-pentaazatriacontan-30-yl)carbamate	609-812-5	402913-84-2	2012	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	(4-nitrophenyl)methanesulfonyl chloride	609-806-2	4025-75-6	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	Diphenylmethyl (6R,7R)-8-oxo-7-[(phenylacetyl)amino]-3-{[4-(pyridin-4-yl)-1,3-thiazol-2-yl]thio}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	609-782-3	400827-68-1	2019	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	2-Chlorobenzoylacetonitrile	609-772-9	40018-25-5	2017	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	21-Hydroxy-16 alpha-methyl-4-pregnene-3,20-dione	609-766-6	39987-86-5	2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	21-Acetoxy-16 alpha-methyl-4-pregnene-3,20-dione	609-765-0	39987-85-4	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid	609-759-8	39961-95-0	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	1H-1,2,4-Triazole-3-carboxylic acid, 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-, methyl ester	609-754-0	39925-10-5	2019	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	-	View substance registered dossier
Innochem NV	B. Adriaensenlaan 66 2450 Meerhout Belgium	Belgium	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	-	View substance registered dossier
Jubilant Lifesciences NV	Axxes Business Park Guldensporenpark 22 - block C 9820 Merelbeke Belgium	Belgium	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	-	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	5-bromo-2-nitropyridine	609-748-8	39856-50-3	2016; 2017	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	5-(1-methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol	609-737-8	3967-32-6	2017	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Active	(9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione	609-736-2	39672-75-8	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	(R)-(-)-1,1'-Binaphthalene-2,2'-diyl hydrogen phosphate	609-734-1	39648-67-4	-	View substance registered dossier
Reuter Chemische Apparatebau e.K.	Engesserstrasse 4b 79108 Freiburg Germany	Germany	Active	(R)-(-)-1,1'-Binaphthalene-2,2'-diyl hydrogen phosphate	609-734-1	39648-67-4	2013	View substance registered dossier
REACH24H CONSULTING GROUP (acts as the OR for SUQIAN UNITECH CORP., LTD)	Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland	Ireland	Active	6-chloro-N,N,N',N'-tetrabutyl-1,3,5-triazine-2,4-diamine	609-724-7	39605-45-3	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	6-chloro-N,N,N',N'-tetrabutyl-1,3,5-triazine-2,4-diamine	609-724-7	39605-45-3	2013; 2023	View substance registered dossier
BASF Italia S.p.A.	Via Marconato 8 20811 Cesano Maderno Italy	Italy	Active	6-chloro-N,N,N',N'-tetrabutyl-1,3,5-triazine-2,4-diamine	609-724-7	39605-45-3	2012	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	1,1-Bis(hydroxymethyl)cyclopropane	609-723-1	39590-81-3	2016	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	1,1-Bis(hydroxymethyl)cyclopropane	609-723-1	39590-81-3	-	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Cease Manufacture	ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate	609-702-7	395068-96-9	2018	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Cease Manufacture	ethyl 2-amino-3-cyclobutylpropanoate	609-695-0	394735-17-2	2019	View substance registered dossier
Beckman Coulter GmbH	Europark Fichtenhain B13 47807 Krefeld Germany	Germany	Active	2-phenoxyethanol; phosphoric acid	609-691-9	39464-70-5	2018	View substance registered dossier
WeylChem Griesheim GmbH	Stroofstr. 27 D-65933 Frankfurt am Main Germany	Germany	Cease Manufacture	5-Fluoro-2-nitrobenzoic acid methyl ester	609-664-1	393-85-1	2019	View substance registered dossier
Aaron Chemistry GmbH	Am Fischweiher 41 82481 Mittenwald Germany	Germany	Active	2,4-Dichloro-5-(trifluoromethyl)pyrimidine	609-648-4	3932-97-6	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	2-chloro-N-(2,4,6-trimethylphenyl)acetamide	609-612-8	3910-51-8	-	View substance registered dossier
PPG Europe B.V. - OR1	Amsterdamseweg 14 1422 AD Uithoorn Netherlands	Netherlands	Active	1,3-bis(isocyanatomethyl)cyclohexane	609-567-4	38661-72-2	-	View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR06	Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands	Netherlands	Active	1,3-bis(isocyanatomethyl)cyclohexane	609-567-4	38661-72-2	2018	View substance registered dossier
Evotec DS Germany GmbH	Kantstrasse 2 33790 Halle/ Westf. Germany	Germany	Active	2,6-Dichloropyridine-3-carboxylic acid	609-561-1	38496-18-3	-	View substance registered dossier
Faes Farma S.A.	Máximo Aguirre 14 48940 Leioa Vizcaya Spain	Spain	Active	2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	-	View substance registered dossier
SONEAS Chemicals Ltd.	Banyaleg Str. 47-59. H-1225 Budapest Hungary	Hungary	Active	2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	-	View substance registered dossier
FINORGA - MOURENX	avenue du lac 64150 MOURENX France	France	Active	2-((6,6-diméthylbicyclo[3.1.1]hept-2-yl)éthoxy)éthyl morpholine	609-541-2	38284-47-8	-	View substance registered dossier
M2I SALIN	112 bureaux de la colline 92213 St Cloud France	France	Active	2-((6,6-diméthylbicyclo[3.1.1]hept-2-yl)éthoxy)éthyl morpholine	609-541-2	38284-47-8	-	View substance registered dossier
Solvay Specialty Polymers Italy S.p.A.	Viale Lombardia 20 20021 BOLLATE Italy	Italy	Active	2-[difluoro(methoxy)methyl]-1,1,1,3,3,3-hexafluoropropane	609-534-4	382-26-3	2016; 2019	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	Reaction product of 2-Propyn-1-ol with methyloxirane	609-530-2	38172-91-7	2017; 2018	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	ethyl 3-amino-2-cyanoprop-2-enoate	609-521-3	38109-77-2	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	8-Chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5Hbenzo[5,6]cyclohepta[1,2-b]pyridin-11-ol	609-518-7	38089-93-9	-	View substance registered dossier
INKE, S.A.	Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain	Spain	Active	8-Chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5Hbenzo[5,6]cyclohepta[1,2-b]pyridin-11-ol	609-518-7	38089-93-9	2010; 2017	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid	609-516-6	38075-43-3	2022	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Active	Glycine, N-acetyl-N-[3-(trifluoromethyl)phenyl]valyl-, ethyl ester	609-496-9	379685-94-6	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1)	609-494-8	37951-53-4	2018	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	6-fluoro-2-methylindan-1-one	609-478-0	37794-19-7	2017	View substance registered dossier
[Confidential]	-	-	-	Benzenamine, 2-[(4-chlorophenyl)thio]-	609-474-9	37750-29-1	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2,3-dimethyl-4-nitro-1-oxidopyridin-1-ium	609-469-1	37699-43-7	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	2018	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	benzhydryl (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-trityloxyiminoacetyl]amino]-3-formyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	609-462-3	376653-37-1	2018	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	2018	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	2-Propenoic acid, 2-cyano-3-(3,4-dimethoxyphenyl)-, (2E)-	609-453-4	37630-52-7	2018	View substance registered dossier
REACHLaw Ltd. (acting as OR for Survival Technologies Private Limited)	Vänrikinkuja 3 JK 21, FI-02600 Espoo Finland Finland	Finland	Active	1,1,1-trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide	609-445-0	37595-74-7	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	1,1,1-trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide	609-445-0	37595-74-7	-	View substance registered dossier
Evotec DS Germany GmbH	Kantstrasse 2 33790 Halle/ Westf. Germany	Germany	Active	1,1,1-trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide	609-445-0	37595-74-7	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	1,1,1-trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide	609-445-0	37595-74-7	2021	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (6E)-	609-442-4	375846-25-6	-	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	4-[(4,6-dihydroxypyrimidin-2-yl)amino]benzonitrile	609-425-1	374067-80-8	2022	View substance registered dossier
DSM Food Specialties France S.A.S.	15, rue des Comtesses B.P. 50239 59472 SECLIN Cedex Nord-Pas-de-Calais France	France	Active	myo-inositol-hexakisphosphate 3-phosphohydrolase	609-386-0	37288-11-2	2018	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	Chloromethylene dimethylammonium chloride	609-368-2	3724-43-4	2021	View substance registered dossier
AGC Chemicals Europe, Ltd	World Trade Centre Zuidplein 80 1077XV Amsterdam Netherlands	Netherlands	Active	N-(2-methylsulfinyl-1,1-dimethyl-ethyl)-N'-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide	609-338-9	371771-07-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	N-(2-methylsulfinyl-1,1-dimethyl-ethyl)-N'-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide	609-338-9	371771-07-2	2010; 2013	View substance registered dossier
3V Sigma S.p.A	Torquato Tasso 58 24121 Bergamo Italy	Italy	Active	Hexasodium 2,2´-[vinylenebis[(3-sulphonato-4,1-phenylene)imino[6-[bis(2-hydroxypropyl)amino]-1,3,5-triazine-4,2-diyl]imino]]bis(benzene-1,4-disulphonate)	609-336-8	371756-75-1	2012	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	N,N-dimethyl-1-adamantanamine	609-335-2	3717-40-6	2013	View substance registered dossier
Sachem Europe BV	Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands	Netherlands	Active	N,N-dimethyl-1-adamantanamine	609-335-2	3717-40-6	-	View substance registered dossier
[Confidential]	-	-	-	Reaction mass of (R)-(-)-1-methoxy-2-propylamine and (S)-(+)-1-methoxy-2-propylamine	609-333-1	37143-54-7	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	1-Ethyl-3-methylimidazolium dicyanamide	609-330-5	370865-89-7	2017; 2020	View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen	Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany	Germany	Active	1-Ethyl-3-methylimidazolium dicyanamide	609-330-5	370865-89-7	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	Methanone, [5-chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)phenyl]phenyl-	609-311-1	36916-19-5	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	6,10,14-Trimethyl-5-Pentadecen-2-on	609-306-4	3689-69-8	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	2-{[(4-Chloro-3-methoxypyridin-2-yl)methyl]sulfanyl)-6-(difluoromethoxy)-1H-benzimidazole	609-304-3	368890-20-4	2009; 2011	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	2-{[(4-Chloro-3-methoxypyridin-2-yl)methyl]sulfanyl)-6-(difluoromethoxy)-1H-benzimidazole	609-304-3	368890-20-4	-	View substance registered dossier
[Confidential]	-	-	-	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide	609-299-8	368421-58-3	-	View substance registered dossier
Reuter Chemische Apparatebau e.K.	Engesserstrasse 4b 79108 Freiburg Germany	Germany	Active	(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid hydrochloride	609-287-2	36760-44-8	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-(chlorocarbonyl)phenyl 3-chloropropanoate	609-280-4	366448-53-5	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-[(3-chloropropanoyl)oxy]benzoic acid	609-278-3	366448-45-5	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	Sodium (4-nitrophenyl)methanesulfonate	609-277-8	36639-50-6	-	View substance registered dossier
Sterling Pharma Solutions Ltd	Dudley NE23 7QG Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	1,4-Benzodioxane-2-carboxylic acid	609-276-2	3663-80-7	2021	View substance registered dossier
Intertek Deutschland GmbH 48	Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany	Germany	Active	2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	2014; 2018; 2022	View substance registered dossier
ArianeGroup	51-61 Route de Verneuil 78130 LES MUREAUX France	France	Active	phosphoramidic dichloride, methyl-	609-264-7	36598-86-4	-	View substance registered dossier
EURO-KEMICAL Srl	via SABBIONCELLI, SNC 24050 COVO (BG) Italy	Italy	Active	disodium butane-1,4-disulfonate	609-262-6	36589-61-4	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2,5-dimethyl-4-[2-methylsulfonyl-4-(trifluoromethyl)benzoyl]-1H-pyrazol-3-one	609-256-3	365400-11-9	2018; 2023	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	3-Methoxy-18-methyl-1,3,5(10)-estratrien-17 beta-ol	609-222-8	3625-82-9	2022	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	3,7,11-Trimethyldodec-1-en-3-ol	609-221-2	3625-46-5	-	View substance registered dossier
[Confidential]	-	-	-	tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate	609-213-9	361440-67-7	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	ethyl 1-[2-(2,4-dichlorophenyl)acetoxy]cyclohexanecarboxylate	609-206-0	361366-16-7	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	ethyl 1-(2-mesitylacetoxy)cyclopentanecarboxylate	609-205-5	361366-15-6	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	6 alpha-Fluoro-11 beta-hydroxy-16 alpha-methyl-21-valeryloxy-1,4-pregnadiene-3,20-dione	609-203-4	36130-02-6	2012; 2018; 2022	View substance registered dossier
Sabinsa Europe GmbH	Monzastrasse 4 63225 Langen Hessen Germany	Germany	Active	3,5-Heptamedopme. 1,7-bis(hydroxy-3methoxyphenyl)heptane	609-201-3	36062-04-1	-	View substance registered dossier
ARCHIMICA S.P.A.	Viale Milano 86 26900 Lodi Italy Italy	Italy	Active	Phosphoric acid, mono(2-aminoethyl) mono(2,3-dihydroxypropyl) ester, monohydrate, (R)-	609-192-6	35907-34-7	2018	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	1-(3-allyl-2-hydroxyphenyl)propan-1-one	609-190-5	35888-91-6	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	5,6-Dihydro-2-[trans,trans-4'-propyl(1,1'-bicyclohexyl-4-yl)-4H-1,3-dithiin-1-iumtrifluoromethanesulfonate	609-186-3	358732-12-4	2022	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	1H,5H-Pyrazolo[1,2-a]pyrazol-1-one, 3-amino-6,7-dihydro-, hydrochloride (1:1)	609-180-0	358360-19-7	-	View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A	via quarta strada 2 35129 padova Italy	Italy	Active	1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one	609-173-2	3575-80-2	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one	609-173-2	3575-80-2	2017	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	1,3,4,5-tetrahydro-2H-1,5-methano-3-benzazepin-2-one	609-171-1	357426-13-2	-	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Active	1,3,4,5-tetrahydro-2H-1,5-methano-3-benzazepin-2-one	609-171-1	357426-13-2	-	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Active	tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	2020	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	-	View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A.	Viale del Ghisallo, 20 20151 Milano Italy	Italy	Active	2,5-bis(2,2,2-trifluoroethoxy)benzoic acid	609-132-9	35480-52-5	-	View substance registered dossier
DSM Nutritional Products France SAS	1 boulevard d'Alsace F-68128 Village-Neuf France	France	Active	Phosphonium, (3-methyl-4-oxo-2-butenyl)triphenyl-, chloride	609-124-5	3541-81-9	2020	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	methyl 10-methoxy-5H-dibenzo[b,f]azepine-5-carboxylate	609-118-2	353497-37-7	2021	View substance registered dossier
METCO SRL	VIA GALILEI 4 40053 VALSAMOGGIA LOC. MONTEVEGLIO BOLOGNA Italy	Italy	Active	Acetic acid, 2-hydroxy-, ammonium salt (1:1)	609-106-7	35249-89-9	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile	609-105-1	35249-62-8	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile	609-105-1	35249-62-8	2018	View substance registered dossier
[Confidential]	-	-	-	Boronic acid, B-(2-fluoro-3-methoxyphenyl)-	609-099-0	352303-67-4	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	10-[4-(2-chloroethyl)piperazin-1-yl]-2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaene	609-095-9	352232-17-8	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile	609-091-7	35202-54-1	2018	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	3-Amino-1-(2-chlorophenyl)-1-phenylpropan-1-ol	609-081-2	35173-30-9	2018	View substance registered dossier
Clariant Plastics & Coatings (Deutschland) GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	Phosphinic acid, diethyl-, sodium salt	609-080-7	35160-38-4	2017	View substance registered dossier
SONEAS Chemicals Ltd.	Banyaleg Str. 47-59. H-1225 Budapest Hungary	Hungary	Active	(Z)-dodec-9-en-1-ol	609-079-1	35148-18-6	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	2016; 2018	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	2017	View substance registered dossier
Trifarma S.p.A.	Via G. Guarini Matteucci 1 20162 Milan (MI) Italy	Italy	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	-	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	2018	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	2,4-Diamino-6-chloropyrimidine-3-oxide	609-076-5	35139-67-4	2018	View substance registered dossier
BASF Espanola S.L.	Calle Can Ràbia, n. 3-5 8017 Barcelona Spain	Spain	Active	2-hydroxy-N,N-dimethyl-propanamide	609-066-0	35123-06-9	2021; 2023	View substance registered dossier
PALCHEM	Rue du Transvaal BP22 62143 ANGRES France	France	Active	1-(ethoxymethoxy)-4-methyl-benzene	609-065-5	35117-05-6	-	View substance registered dossier
Nouryon Functional Chemicals B.V.	Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands	Netherlands	Active	1-(ethoxymethoxy)-4-methyl-benzene	609-065-5	35117-05-6	2019	View substance registered dossier
[Confidential]	-	-	-	2-ISOPROPYL-1,3-DIOXANE-5,5-DICARBOXYLIC ACID DIETHYL ESTER	609-063-4	35113-48-5	-	View substance registered dossier
Simafex	16 av des fours à chaux 17230 Marans France	France	Active	2-ISOPROPYL-1,3-DIOXANE-5,5-DICARBOXYLIC ACID DIETHYL ESTER	609-063-4	35113-48-5	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	potassium (2S)-2-{[(2Z)-4-ethoxy-4-oxobut-2-en-2-yl]amino}propanoate	609-057-1	35052-92-7	-	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	potassium (2S)-2-{[(2Z)-4-ethoxy-4-oxobut-2-en-2-yl]amino}propanoate	609-057-1	35052-92-7	2021	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	potassium (2S)-2-{[(2Z)-4-ethoxy-4-oxobut-2-en-2-yl]amino}propanoate	609-057-1	35052-92-7	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate	609-054-5	35011-47-3	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(2-(tert-butoxy)-2-oxoethyl)triphenylphosphonium chloride	609-051-9	35000-37-4	-	View substance registered dossier
HOBUM Oleochemicals GmbH	Konsul-Ritter-Str. 10 21079 Hamburg Germany	Germany	Active	2-(dimethylamino)ethyl dodecanoate	609-033-0	34839-10-6	-	View substance registered dossier
Vertellus Specialties UK Ltd	St Ann's Wharf NE1 3DX Newcastle Upon Tyne United Kingdom	United Kingdom	No longer Valid	2-(diphenylphosphino)benzonitrile	609-030-4	34825-99-5	2021	View substance registered dossier
JSC "Olainfarm"	Rupnicu str. 5 LV-2114 Olaine Latvia	Latvia	Active	Ethyl [10-(3-chloropropanoyl)-10H-phenothiazin-2-yl]carbamate	609-026-2	34749-22-9	-	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride	609-015-2	3464-71-9	-	View substance registered dossier
Chemours France S.A.S.	Rue Frederic Kuhlmann 60870 Villers-Saint-Paul France	France	Active	N-[3-(dimethylamino)propyl]-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octane-1-sulfonamide	608-993-8	34455-22-6	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Cease Manufacture	4-Propionylcyclohexylbenzol	608-991-7	344348-40-9	2019	View substance registered dossier
Roche Diagnostics GmbH	Sandhoferstrasse 116 68305 Mannheim Germany	Germany	Active	(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID	608-945-6	340-90-9	2019; 2022	View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH	Riedstrasse 2 89555 Steinheim Germany	Germany	Active	(2S)-2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)PENTANEDIOIC ACID	608-945-6	340-90-9	-	View substance registered dossier
Sun Chemical Colors & Effects GmbH	An der Rheinschanze 1 67059 Ludwigshafen Germany	Germany	Active	1H-benzo[10,5]anthra[2,1,9-def]isoquinoline-1,3(2H)-dione	608-929-9	33955-44-1	-	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	3-[(4-Fluorophenyl)thio]-2-hydroxy-2-methylpropanoic acid	608-927-8	339530-91-5	-	View substance registered dossier
POLPHARMA	19 Pelplińska 83-200 Starogard Gdański Poland	Poland	Active	5H-Dibenz[b,f]azepine-5-carbonyl chloride	608-925-7	33948-22-0	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	Methyl-6-bromo-2-naphthoate	608-896-0	33626-98-1	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	cyclobutane-1,1-dicarboxamide	608-895-5	33582-68-2	-	View substance registered dossier
AIR LIQUIDE FRANCE INDUSTRIE	EL- AMC-EMC Chalon Archibald Scandocs Center / 0715 - CS 80010 81700 BLAN France	France	Active	trimethoxy(3-methoxypropyl)silane	608-893-4	33580-59-5	-	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	O-(4-Nitrophenyl)hydroxylamine	608-888-7	33543-55-4	2018	View substance registered dossier
Sterling Pharma Solutions Ltd	Dudley NE23 7QG Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	2-(2-Formyl-4-nitrophenoxy)hexanoic acid	608-880-3	335153-21-4	2021	View substance registered dossier
Cytec Industries BV as OR for Solvay Solutions UK Limited	Weena 505 3013 AL Rotterdam Rotterdam Netherlands Netherlands	Netherlands	Cease Manufacture	Di-tert-butyl phosphate	608-874-0	33494-81-4	2021	View substance registered dossier
Reuter Chemische Apparatebau e.K.	Engesserstrasse 4b 79108 Freiburg Germany	Germany	Active	(R)-(-)-3-Aminopiperidine dihydrochloride	608-870-9	334618-23-4	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	1-(diphenylmethyl)azetidin-3-yl methanesulfonate	608-857-8	33301-41-6	-	View substance registered dossier
CURIA SPAIN, S.A.U.	Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain	Spain	Active	(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile	608-856-2	33300-19-5	2018	View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A.	Viale del Ghisallo, 20 20151 Milano Italy	Italy	Active	2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-	608-855-7	33288-71-0	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-	608-855-7	33288-71-0	2018	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-	608-855-7	33288-71-0	2022	View substance registered dossier
[Confidential]	-	-	-	Benzeneacetic acid, 3-ethoxy-4-(ethoxycarbonyl)-, ethyl ester	608-847-3	332347-69-0	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	(S)-2-aminopropanamide hydrochloride	608-843-1	33208-99-0	2017	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	Methyl (Z)-2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)-2-((trityloxy)imino) acetate	608-838-4	331780-39-3	-	View substance registered dossier
Archroma France, SAS	Rue du Flottage 60350 Trosly-Breuil France	France	Active	sodium;2-chloroprop-2-enoate;hydrate	608-818-5	32997-86-7	2019	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	(4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate	608-799-3	329181-36-4	-	View substance registered dossier

Showing 6,801 - 7,000 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.