Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104986 dossiers.
Substance identity
Administrative data
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First published date:
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Substance data
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Uses and exposure
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Details
Titanium tetrachloride
231-441-9 7550-45-0 Cease Manufacture Intermediate Individual Cease manufacture 29-05-2012 View substance registered dossier
Titanium tetraisopropanolate
208-909-6 546-68-9 Active Intermediate Individual Intermediate use only 30-11-2012 View substance registered dossier
Titanium trichloride
231-728-9 7705-07-9 Cease Manufacture Intermediate Individual Cease manufacture 28-11-2011 View substance registered dossier
Titanium(4+) oxalate
403-260-7 31363-92-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Titanium, (S) - lactate polyethylene glycol triisopropanolamine ammonium complexes
410-660-5 1072830-14-8 Active Full Individual ≥ 100 to < 1 000 tonnes 02-01-2014 View substance registered dossier
Titanium, (S) - lactate polyethylene glycol triisopropanolamine ammonium complexes
410-660-5 1072830-14-8 No longer Valid NONS Individual No longer valid 18-03-2011 View substance registered dossier
Titanium, [N-(1,1-dimethylethyl)-1,1-dimethyl-1-[(1,2,3,3a,8a-.eta.)-1,5,6,7-tetrahydro-2-methyl-s-indacen-1-yl]silanaminato(2-)-.kappa.N][1,2,3,4-.eta.)-1,3-pentadiene]-
433-370-0 210301-31-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Titanium, bis (5-2,4-cyclopentadien-1-yl)bis(4-methoxyphenyl)-
601-790-5 12156-55-7 Active Intermediate Individual Intermediate use only 28-03-2018 View substance registered dossier
TIXOGEL VP-V
436-030-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TM-300
442-140-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TMCH
421-590-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TMCPO
431-810-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TMIP
438-860-8 - Active NONS Individual Tonnage data confidential 29-04-2011 View substance registered dossier
TMX 7
437-560-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TOK-116
439-920-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TOMILAC 214
- - Cease Manufacture Full Individual Cease manufacture 12-08-2014 View substance registered dossier
TOMP-MESYLAT
424-960-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TOX
433-670-1 - Active NONS Individual Tonnage data confidential 30-11-2012 View substance registered dossier
TOXEPYRON
453-120-4 - Active NONS Individual Tonnage data confidential 11-03-2011 View substance registered dossier
TPS 15
415-790-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Trade name: 3M(TM) NOVEC(TM) ENGINEERED FLUID HFE-7000
484-450-7 - Active NONS Individual Tonnage data confidential 20-06-2013 View substance registered dossier
Trans 2,6,6-trimethyl-3-cyclohexen-1-yl]trichloroethanone
918-495-5 - Active Intermediate Individual Intermediate use only 20-04-2018 View substance registered dossier
trans,trans-4,4'-di-(1-propenyl)-trans-1,1'-bicyclohexane
434-060-8 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide
417-290-3 147086-81-5 Active Intermediate Individual Intermediate use only 27-10-2010 View substance registered dossier
trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide
417-290-3 147086-81-5 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
trans-(5RS,6SR)-6-amino-2,2-dimethyl-1,3-dioxepan-5-ol
419-050-3 79944-37-9 Active Intermediate Individual Intermediate use only 18-11-2010 View substance registered dossier
trans-1,4-bis(iodomethyl)cyclohexane
800-300-9 83447-96-5 Cease Manufacture Intermediate Individual Cease manufacture 23-04-2013 View substance registered dossier
Trans-2,6-dimethylindan-1-amine
700-575-4 1351564-23-2 Active Intermediate Individual Intermediate use only 23-09-2011 View substance registered dossier
trans-2-Cyclododecenyl propanoic acid ethylester
601-534-2 118562-69-9 Active Intermediate Individual Intermediate use only 27-02-2019 View substance registered dossier
trans-2-isopropyl-5-carboxy-1,3-dioxane
445-770-2 42031-28-7 Active Intermediate Individual Intermediate use only 11-11-2011 View substance registered dossier
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol Hydrobromide
926-606-3 - Active Intermediate Individual Intermediate use only 11-05-2015 View substance registered dossier
TRANS-4-(CYCLOHEXANE-4'-ONE)1-P-TOLYL-CYCLOHEXANE
435-110-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol
641-602-9 50910-53-7 Active Intermediate Individual Intermediate use only 13-04-2018 View substance registered dossier
trans-4-aminocyclohexan-1-ol
248-492-8 27489-62-9 Active Intermediate Individual Intermediate use only 09-03-2012 View substance registered dossier
trans-4-pentyl-trans-4'-trifluoromethyl-(1,1'-bicyclohexyl)
453-070-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
trans-4-phenyl-L-proline
416-020-1 96314-26-0 Active Intermediate Individual Intermediate use only 13-04-2017 View substance registered dossier
trans-5-(trans-4-ethylcyclohexyl)-2-(3,4,5-trifluorophenyl)-1,3-dioxane
448-110-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
trans-7,7'-dimethyl-(4H,4H')-(2,2')bi[benzo[1,4]thiazinylidene]-3,3'-dione
444-750-0 211387-26-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
trans-cinnamic acid
205-398-1 140-10-3 Active Intermediate Individual Intermediate use only 31-03-2016 View substance registered dossier
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate
700-316-5 1155405-88-1 Active Full Individual ≥ 100 to < 1 000 tonnes 01-02-2013 View substance registered dossier
TRIACONTYLMETHYL DIMETHYLSILOXANE COPOLYMER WITH STABILISERS
435-770-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Triammonium 4-[2,7-dihydro-3-methyl-2,7-dioxo-1-(3-sulfonatobenzoyl)-3H-naphtho[1,2,3-de]quinoline-6-ylamino]benzene-1,3-disulfonate
461-280-1 - Active NONS Individual Tonnage data confidential 14-01-2020 View substance registered dossier
triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy-3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate
432-270-4 221354-37-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Triammonium salt of 2,2',2'',2'''-(cyclohexane-1,2-diyldinitrilo)tetraacetic acid
700-166-0 1333311-43-5 Active Intermediate Individual Intermediate use only 13-01-2010 View substance registered dossier
TRIAZIN ST PINA
440-660-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
TRIAZINE 133 - 38
438-580-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Tributyl phosphate
204-800-2 126-73-8 No longer Valid Full Individual No longer valid 31-10-2012 View substance registered dossier
tributyl(ethyl)phosphonium diethyl phosphate
801-347-8 20445-94-7 Active Full Individual ≥ 0 to < 10 tonnes 30-05-2019 View substance registered dossier
Tributyl-2-thiourea
219-350-2 2422-88-0 Active Full Individual ≥ 0 to < 10 tonnes 22-01-2018 View substance registered dossier
Tributyltetradecylphosphonium tetrafluoroborate
413-520-1 125792-14-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
GRACE GmbH (OR1) In der Hollerhecke 1 67547 Worms Germany Germany Cease Manufacture Titanium tetrachloride 231-441-9 7550-45-0 2016 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Titanium tetraisopropanolate 208-909-6 546-68-9 - View substance registered dossier
GRACE GmbH (OR1) In der Hollerhecke 1 67547 Worms Germany Germany Cease Manufacture Titanium trichloride 231-728-9 7705-07-9 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Titanium(4+) oxalate 403-260-7 31363-92-5 - View substance registered dossier
Borica Europe BVBA Elzenstraat 31 3950 Bocholt Belgium Belgium Active Titanium, (S) - lactate polyethylene glycol triisopropanolamine ammonium complexes 410-660-5 1072830-14-8 - View substance registered dossier
Johnson Matthey PLC 5th Floor, 25 Farringdon Street EC4A 4AB London United Kingdom United Kingdom No longer Valid Titanium, (S) - lactate polyethylene glycol triisopropanolamine ammonium complexes 410-660-5 1072830-14-8 2021 View substance registered dossier
- - - - Titanium, [N-(1,1-dimethylethyl)-1,1-dimethyl-1-[(1,2,3,3a,8a-.eta.)-1,5,6,7-tetrahydro-2-methyl-s-indacen-1-yl]silanaminato(2-)-.kappa.N][1,2,3,4-.eta.)-1,3-pentadiene]- 433-370-0 210301-31-8 - View substance registered dossier
General Química S.A.U. Carretera Miranda-Puentelarrá km 5 01213 Comunión Alava Spain Spain Active Titanium, bis (5-2,4-cyclopentadien-1-yl)bis(4-methoxyphenyl)- 601-790-5 12156-55-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active TIXOGEL VP-V 436-030-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active TM-300 442-140-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active TMCH 421-590-1 - - View substance registered dossier
- - - - TMCPO 431-810-6 - - View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active TMIP 438-860-8 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active TMX 7 437-560-4 - - View substance registered dossier
- - - - TOK-116 439-920-6 - - View substance registered dossier
Mitsubishi Chemical Europe GmbH Willstätter Strasse 30 40549 Düsseldorf Germany Germany Cease Manufacture TOMILAC 214 - - 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active TOMP-MESYLAT 424-960-9 - - View substance registered dossier
- - - - TOX 433-670-1 - - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active TOXEPYRON 453-120-4 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active TPS 15 415-790-6 - - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active Trade name: 3M(TM) NOVEC(TM) ENGINEERED FLUID HFE-7000 484-450-7 - 2011; 2013 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active Trans 2,6,6-trimethyl-3-cyclohexen-1-yl]trichloroethanone 918-495-5 - - View substance registered dossier
- - - - trans,trans-4,4'-di-(1-propenyl)-trans-1,1'-bicyclohexane 434-060-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide 417-290-3 147086-81-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide 417-290-3 147086-81-5 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active trans-(5RS,6SR)-6-amino-2,2-dimethyl-1,3-dioxepan-5-ol 419-050-3 79944-37-9 2010 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture trans-1,4-bis(iodomethyl)cyclohexane 800-300-9 83447-96-5 2018 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active Trans-2,6-dimethylindan-1-amine 700-575-4 1351564-23-2 - View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active trans-2-Cyclododecenyl propanoic acid ethylester 601-534-2 118562-69-9 2019 View substance registered dossier
[Confidential] - - - trans-2-isopropyl-5-carboxy-1,3-dioxane 445-770-2 42031-28-7 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol Hydrobromide 926-606-3 - - View substance registered dossier
- - - - TRANS-4-(CYCLOHEXANE-4'-ONE)1-P-TOLYL-CYCLOHEXANE 435-110-1 - - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol 641-602-9 50910-53-7 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active trans-4-aminocyclohexan-1-ol 248-492-8 27489-62-9 - View substance registered dossier
- - - - trans-4-pentyl-trans-4'-trifluoromethyl-(1,1'-bicyclohexyl) 453-070-3 - - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active trans-4-phenyl-L-proline 416-020-1 96314-26-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active trans-5-(trans-4-ethylcyclohexyl)-2-(3,4,5-trifluorophenyl)-1,3-dioxane 448-110-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active trans-7,7'-dimethyl-(4H,4H')-(2,2')bi[benzo[1,4]thiazinylidene]-3,3'-dione 444-750-0 211387-26-7 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active trans-cinnamic acid 205-398-1 140-10-3 - View substance registered dossier
IOI Oleo GmbH Herrengraben 31 20459 Hamburg Germany Germany Active Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate 700-316-5 1155405-88-1 2010; 2011; 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active TRIACONTYLMETHYL DIMETHYLSILOXANE COPOLYMER WITH STABILISERS 435-770-0 - - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 044 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active Triammonium 4-[2,7-dihydro-3-methyl-2,7-dioxo-1-(3-sulfonatobenzoyl)-3H-naphtho[1,2,3-de]quinoline-6-ylamino]benzene-1,3-disulfonate 461-280-1 - 2012; 2013; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy-3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate 432-270-4 221354-37-6 - View substance registered dossier
SA DABEER C/ Pasaje Arrahona 18 2º 08210 Barbera del Vallés Spain Spain Active Triammonium salt of 2,2',2'',2'''-(cyclohexane-1,2-diyldinitrilo)tetraacetic acid 700-166-0 1333311-43-5 2010 View substance registered dossier
- - - - TRIAZIN ST PINA 440-660-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active TRIAZINE 133 - 38 438-580-6 - - View substance registered dossier
Ecotoxward Ltd 381-383 City Road EC1V 1NW London United Kingdom United Kingdom No longer Valid Tributyl phosphate 204-800-2 126-73-8 2021 View substance registered dossier
Cytec Industries BV Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active tributyl(ethyl)phosphonium diethyl phosphate 801-347-8 20445-94-7 - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Tributyl-2-thiourea 219-350-2 2422-88-0 - View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Cease Manufacture Tributyltetradecylphosphonium tetrafluoroborate 413-520-1 125792-14-5 2018 View substance registered dossier

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