Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104986 dossiers.
Substance identity
Administrative data
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Substance data
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Uses and exposure
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Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate
425-220-8 5945-33-5 Cease Manufacture Full Individual Cease manufacture 20-11-2012 View substance registered dossier
(10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
810-248-9 104746-04-5 Cease Manufacture Intermediate Individual Cease manufacture 09-06-2015 View substance registered dossier
(13S-cis)-13-ethyl-7,11,12,13,16,17-hexahydro-3-methoxy-6H-cyclopenta[a]phenantren-17-ol
238-512-3 14507-45-0 Active Intermediate Individual Intermediate use only 25-08-2016 View substance registered dossier
(17β)-3-oxoestra-4,6-dien-17-yl acetate
425-330-6 - Active NONS Individual Tonnage data confidential 26-01-2011 View substance registered dossier
(1E)-5-methyl-1-phenylhex-1-en-3-one
808-311-0 60796-12-5 Active Intermediate Individual Intermediate use only 24-02-2015 View substance registered dossier
(1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine
700-765-7 100485-51-6 Cease Manufacture Intermediate Individual Cease manufacture 07-12-2012 View substance registered dossier
(1E,Z)-2,6-dimethylhepta-1,5-dienyl 2-methylpropanoate
479-370-4 942594-24-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 100 to < 1 000 tonnes 21-02-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 100 to < 1 000 tonnes 16-01-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 13-04-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 05-11-2010 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 22-03-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 22-01-2016 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 27-10-2011 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 25-03-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 23-09-2014 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 17-08-2012 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 02-04-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 21-05-2013 View substance registered dossier
(1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
600-381-9 1030385-16-0 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
(1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1)
927-046-2 1180001-17-5 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
(1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate
700-689-4 41524-32-7 Active Intermediate Individual Intermediate use only 21-09-2011 View substance registered dossier
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide
600-115-1 1006376-62-0 Active Intermediate Individual Intermediate use only 29-01-2018 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 752984-24-0 Active Intermediate Individual Intermediate use only 18-05-2011 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Cease Manufacture (1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate 425-220-8 5945-33-5 2014 View substance registered dossier
[Confidential] - - - (10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide 810-248-9 104746-04-5 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (13S-cis)-13-ethyl-7,11,12,13,16,17-hexahydro-3-methoxy-6H-cyclopenta[a]phenantren-17-ol 238-512-3 14507-45-0 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (17β)-3-oxoestra-4,6-dien-17-yl acetate 425-330-6 - 2011 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (1E)-5-methyl-1-phenylhex-1-en-3-one 808-311-0 60796-12-5 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Cease Manufacture (1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine 700-765-7 100485-51-6 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1E,Z)-2,6-dimethylhepta-1,5-dienyl 2-methylpropanoate 479-370-4 942594-24-3 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate 941-846-9 - - View substance registered dossier
TÜV SÜD Iberia, S.A.U. (068) Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain Spain Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2013 View substance registered dossier
Covance Clinical Development SA 098 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain Spain Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2015 View substance registered dossier
ADEKA PALMAROLE SAS 13 rue du 17 Novembre FR-68100 MULHOSE France France Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
ADEKA POLYMER ADDITIVES EUROPE SAS 13 rue du 17 Novembre FR-68100 MULHOUSE France France Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
[Confidential] - - - (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Handelsvertretung Sabine Alisch Fontaneweg 22 16547 Birkenwerder Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
KTR Europe GmbH Mergenthalerallee 77 65760 Eschborn Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Borealis AG Wagramerstrasse 17-19 1220 Wien Austria Austria Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Everspring Europe Sprl Rue Rodenbach 125 1190 Brussels Belgium Belgium Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2014 View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2018 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 600-381-9 1030385-16-0 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) 927-046-2 1180001-17-5 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate 700-689-4 41524-32-7 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide 600-115-1 1006376-62-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 752984-24-0 2011 View substance registered dossier

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