Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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First published date:
Last update date:
Substance data
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Uses and exposure
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Details
Methyl heptafluorobutyrate
206-600-0 356-24-1 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
Trifluoromethanesulphonic anhydride
206-616-8 358-23-6 Active Full Joint ≥ 100 to < 1 000 tonnes 03-04-2020 View substance registered dossier
2-bromo-1,1-difluoroethylene
206-624-1 359-08-0 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
o-(trifluoromethyl)benzamide
206-637-2 360-64-5 Active Intermediate Joint Intermediate use only 16-09-2019 View substance registered dossier
Sodium cholate
206-643-5 361-09-1 Active Full Joint ≥ 10 to < 100 tonnes 26-05-2018 View substance registered dossier
2',3'-isopropylideneuridine
206-647-7 362-43-6 Active Intermediate Joint Intermediate use only 13-10-2020 View substance registered dossier
Metoclopramide
206-662-9 364-62-5 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2,2'-bipyridyl
206-674-4 366-18-7 Active Intermediate Joint Intermediate use only 14-09-2020 View substance registered dossier
3-chloro-4-fluoroaniline
206-682-8 367-21-5 Active Intermediate Joint Intermediate use only 14-10-2020 View substance registered dossier
2,4-difluoroaniline
206-687-5 367-25-9 Active Intermediate Individual Intermediate use only 01-04-2011 View substance registered dossier
2,4-difluoroaniline
206-687-5 367-25-9 Active Intermediate Joint Intermediate use only 19-02-2019 View substance registered dossier
Sodium mercaptoacetate
206-696-4 367-51-1 Active Full Joint ≥ 100 to < 1 000 tonnes 13-09-2021 View substance registered dossier
1,2-difluoro-4-nitrobenzene
206-718-2 369-34-6 Active Intermediate Joint Intermediate use only 30-10-2017 View substance registered dossier
4-fluoroaniline
206-735-5 371-40-4 Active Full Joint ≥ 0 to < 10 tonnes 29-04-2016 View substance registered dossier
4-fluoroaniline
206-735-5 371-40-4 Active Intermediate Joint Intermediate use only 14-09-2020 View substance registered dossier
4-fluorophenol
206-736-0 371-41-5 Active Full Joint ≥ 0 to < 10 tonnes 23-09-2016 View substance registered dossier
4-fluorophenol
206-736-0 371-41-5 No longer Valid Intermediate Joint No longer valid 03-10-2019 View substance registered dossier
Disodium maleate
206-738-1 371-47-1 Active Intermediate Joint Intermediate use only 18-11-2016 View substance registered dossier
Cyanoacetic acid
206-743-9 372-09-8 Active Intermediate Individual Intermediate use only 16-04-2014 View substance registered dossier
Cyanoacetic acid
206-743-9 372-09-8 Active Intermediate Joint Intermediate use only 12-06-2018 View substance registered dossier
1,3-difluorobenzene 206-746-5 372-18-9 Active Full Joint ≥ 1 to < 10 tonnes 21-12-2018 View substance registered dossier
1,3-difluorobenzene 206-746-5 372-18-9 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
Ethyl 4,4,4-trifluoroacetoacetate
206-750-7 372-31-6 Active Full Joint ≥ 0 to < 10 tonnes 11-01-2013 View substance registered dossier
Ethyl 4,4,4-trifluoroacetoacetate
206-750-7 372-31-6 Active Intermediate Joint Intermediate use only 29-10-2019 View substance registered dossier
Nickel di(acetate) 206-761-7 373-02-4 Active Full Joint ≥ 10 to < 100 tonnes 30-06-2021 View substance registered dossier
Nickel di(acetate) 206-761-7 373-02-4 Cease Manufacture Intermediate Joint Cease manufacture 15-04-2018 View substance registered dossier
Octamethylenediamine
206-764-3 373-44-4 Active Full Joint ≥ 10 to < 100 tonnes 13-05-2013 View substance registered dossier
Dihydrogen bis(acetato-O)difluoroborate(1-) 206-768-5 373-61-5 Active Full Joint ≥ 10 to < 100 tonnes 24-04-2019 View substance registered dossier
2,2,2-trifluoroethylamine hydrochloride
206-771-1 373-88-6 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
3,3,4,4,4-pentafluorobut-1-ene
206-775-3 374-27-6 Active Full Joint ≥ 1 to < 10 tonnes 15-10-2018 View substance registered dossier
2,2,3,3,4,4,4-heptafluorobutan-1-ol
206-782-1 375-01-9 Active Intermediate Joint Intermediate use only 20-05-2019 View substance registered dossier
1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane
206-788-4 375-50-8 Active Intermediate Joint Intermediate use only 28-07-2020 View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride 206-792-6 375-72-4 Active Intermediate Joint Intermediate use only 12-05-2018 View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid 206-793-1 375-73-5 Active Full Joint ≥ 1 to < 10 tonnes 25-05-2018 View substance registered dossier
1,6-diiodoperfluorohexane
206-794-7 375-80-4 Active Intermediate Joint Intermediate use only 19-05-2016 View substance registered dossier
Betamethasone
206-825-4 378-44-9 Active Full Joint ≥ 1 to < 10 tonnes 20-12-2017 View substance registered dossier
Difluoroacetic acid
206-839-0 381-73-7 Active Full Joint ≥ 10 to < 100 tonnes 08-10-2018 View substance registered dossier
3,3,3-trifluoro-2-(trifluoromethyl)propene
206-840-6 382-10-5 Active Full Joint ≥ 1 to < 10 tonnes 08-08-2017 View substance registered dossier
2,2,3,3,5,5,6,6-octafluoro-4-(trifluoromethyl)morpholine
206-841-1 382-28-5 Active Full Joint ≥ 100 to < 1 000 tonnes 24-06-2013 View substance registered dossier
Ethyl trifluoroacetate
206-851-6 383-63-1 Active Full Joint ≥ 1 to < 10 tonnes 06-07-2021 View substance registered dossier
Ethyl trifluoroacetate
206-851-6 383-63-1 Active Intermediate Joint Intermediate use only 29-06-2018 View substance registered dossier
2,6-difluorobenzoic acid
206-856-3 385-00-2 Active Intermediate Joint Intermediate use only 10-04-2018 View substance registered dossier
4-nitro-3-(trifluoromethyl)aniline
206-884-6 393-11-3 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
4-bromo-α,α,α-trifluoro-m-toluidine
206-885-1 393-36-2 Active Intermediate Joint Intermediate use only 08-11-2016 View substance registered dossier
2-fluorobenzoyl chloride
206-887-2 393-52-2 Active Intermediate Joint Intermediate use only 23-05-2019 View substance registered dossier
4-chloro-3,5-dinitro-α,α,α-trifluorotoluene
206-889-3 393-75-9 Cease Manufacture Intermediate Individual Cease manufacture 24-05-2013 View substance registered dossier
4-chloro-3,5-dinitro-α,α,α-trifluorotoluene
206-889-3 393-75-9 Active Intermediate Individual Intermediate use only 26-04-2011 View substance registered dossier
Isopropyl trifluoroacetate
206-922-1 400-38-4 Active Full Joint ≥ 0 to < 10 tonnes 13-11-2017 View substance registered dossier
α,α,α,3-tetrafluorotoluene
206-933-1 401-80-9 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
α,α,α-trifluoro-3,5-dinitrotoluene
206-935-2 401-99-0 Active Intermediate Joint Intermediate use only 17-02-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Methyl heptafluorobutyrate 206-600-0 356-24-1 - View substance registered dossier
Central Glass Germany GmbH Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany Germany Active Trifluoromethanesulphonic anhydride 206-616-8 358-23-6 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Trifluoromethanesulphonic anhydride 206-616-8 358-23-6 - View substance registered dossier
REACHLaw Ltd. (acting as OR for Survival Technologies Private Limited) Vänrikinkuja 3 JK 21, FI-02600 Espoo Finland Finland Finland Active Trifluoromethanesulphonic anhydride 206-616-8 358-23-6 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Trifluoromethanesulphonic anhydride 206-616-8 358-23-6 2018 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active Trifluoromethanesulphonic anhydride 206-616-8 358-23-6 2020 View substance registered dossier
Dyneon GmbH Industrieparkstrasse 1 84508 Burgkirchen a. d. Alz Germany Germany Active 2-bromo-1,1-difluoroethylene 206-624-1 359-08-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active o-(trifluoromethyl)benzamide 206-637-2 360-64-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active o-(trifluoromethyl)benzamide 206-637-2 360-64-5 - View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture o-(trifluoromethyl)benzamide 206-637-2 360-64-5 2019 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active o-(trifluoromethyl)benzamide 206-637-2 360-64-5 2017 View substance registered dossier
Robinson Brothers Ltd Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom United Kingdom No longer Valid o-(trifluoromethyl)benzamide 206-637-2 360-64-5 2021 View substance registered dossier
Oxoid Deutschland GmbH Am Lippeglacis 4-8 46483 Wesel Germany Germany Active Sodium cholate 206-643-5 361-09-1 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Sodium cholate 206-643-5 361-09-1 - View substance registered dossier
ICE S.p.A. Via Sicilia 8/10 42100 Reggio Emilia Italy Italy Active Sodium cholate 206-643-5 361-09-1 - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 2',3'-isopropylideneuridine 206-647-7 362-43-6 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2',3'-isopropylideneuridine 206-647-7 362-43-6 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active Metoclopramide 206-662-9 364-62-5 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active Metoclopramide 206-662-9 364-62-5 - View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active Metoclopramide 206-662-9 364-62-5 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Metoclopramide 206-662-9 364-62-5 - View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active Metoclopramide 206-662-9 364-62-5 - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 2,2'-bipyridyl 206-674-4 366-18-7 2020 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 3-chloro-4-fluoroaniline 206-682-8 367-21-5 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Cease Manufacture 3-chloro-4-fluoroaniline 206-682-8 367-21-5 2020 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 3-chloro-4-fluoroaniline 206-682-8 367-21-5 - View substance registered dossier
Only representative (No publishable name) - - Active 2,4-difluoroaniline 206-687-5 367-25-9 - View substance registered dossier
Bayer CropScience Ltd. 230 Cambridge Science Park Milton Road CB4 0WB Cambridge Cambridgeshire United Kingdom United Kingdom No longer Valid 2,4-difluoroaniline 206-687-5 367-25-9 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2,4-difluoroaniline 206-687-5 367-25-9 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
Chemisches Labor Franz GmbH Kiefernweg 16 64665 Alsbach-Hähnlein Germany Germany Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
TFL France SAS 4, rue de l'industrie 68333 Huningue Cedex France France Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
DERMAKIM s.r.l. Maja 3 21051 ARCISATE LOMBARDIA/VARESE Italy Italy Active Sodium mercaptoacetate 206-696-4 367-51-1 2021 View substance registered dossier
Bruno Bock Chemische Fabrik GmbH & Co. KG Eichholzer Straße 23 21436 Marschacht Lower Saxony Germany Germany Active Sodium mercaptoacetate 206-696-4 367-51-1 2013; 2014 View substance registered dossier
Dr. Spiess Chemische Fabrik GmbH Hauptstr. 4 67271 Kleinkarlbach Rheinland-Pfalz Germany Germany Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
Wall Chemie GmbH Am Selder 25 47906 Kempen Germany Germany Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
BIOKIMICA SPA VIA DEI CONCIATORI, 44 56029 SANTA CROCE SULL'ARNO (PI) Italy Italy Active Sodium mercaptoacetate 206-696-4 367-51-1 2018 View substance registered dossier
Stahl Italy S.r.l. Via A. Manzoni 37 loc. Palazzolo M.se 20037 Paderno Dugnano MI Italy Italy Active Sodium mercaptoacetate 206-696-4 367-51-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 1,2-difluoro-4-nitrobenzene 206-718-2 369-34-6 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-fluoroaniline 206-735-5 371-40-4 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-fluoroaniline 206-735-5 371-40-4 2015; 2016 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-fluoroaniline 206-735-5 371-40-4 2020 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-fluorophenol 206-736-0 371-41-5 - View substance registered dossier
Corteva Agriscience France S.A.S. Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France France Active 4-fluorophenol 206-736-0 371-41-5 - View substance registered dossier
Wychem Limited Bury Road CB8 8YN Stradishall Suffolk United Kingdom United Kingdom No longer Valid 4-fluorophenol 206-736-0 371-41-5 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Disodium maleate 206-738-1 371-47-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Cyanoacetic acid 206-743-9 372-09-8 2013 View substance registered dossier
Chemical Inspection & Regulation Service Limited(HEBEI CHENGXIN CO., LTD.) Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
MITSUI AND CO. ITALIA S.P.A. PIAZZA DEL LIBERTY 2 20121 MILAN Italy Italy Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture Cyanoacetic acid 206-743-9 372-09-8 2016 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active Cyanoacetic acid 206-743-9 372-09-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 1,3-difluorobenzene 206-746-5 372-18-9 2018 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 1,3-difluorobenzene 206-746-5 372-18-9 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active 1,3-difluorobenzene 206-746-5 372-18-9 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
Lonza Cologne GmbH - REACH Nattermannallee 1 50829 Cologne Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 2017 View substance registered dossier
TODINI AND CO. SPA Corso Milano 46 B 20900 MONZA ITALIA Italy Italy Active Nickel di(acetate) 206-761-7 373-02-4 2017 View substance registered dossier
BLUESTONE METALS & CHEMICALS EUROPE S.L. c/ Pascual y Genis 1 46002 Valencia Spain Spain Active Nickel di(acetate) 206-761-7 373-02-4 - View substance registered dossier
Königswarter & Ebell, Chemische Fabrik GmbH Im Ennepetal 19-21 58135 Hagen Germany Germany Active Nickel di(acetate) 206-761-7 373-02-4 2017 View substance registered dossier
Umicore NV/SA Rue du Marais 31 1000 Brussels Belgium Belgium Active Nickel di(acetate) 206-761-7 373-02-4 2011; 2012; 2013; 2014; 2015; 2016; 2017; 2018; 2019; 2020; 2021 View substance registered dossier
Arcerion GmbH Gabrielenstr. 15 80636 Muenchen Germany Germany Cease Manufacture Nickel di(acetate) 206-761-7 373-02-4 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Octamethylenediamine 206-764-3 373-44-4 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Dihydrogen bis(acetato-O)difluoroborate(1-) 206-768-5 373-61-5 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Dihydrogen bis(acetato-O)difluoroborate(1-) 206-768-5 373-61-5 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active Dihydrogen bis(acetato-O)difluoroborate(1-) 206-768-5 373-61-5 - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active Dihydrogen bis(acetato-O)difluoroborate(1-) 206-768-5 373-61-5 - View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active 2,2,2-trifluoroethylamine hydrochloride 206-771-1 373-88-6 - View substance registered dossier
AGC Chemicals Europe, Ltd World Trade Centre Zuidplein 80 1077VX Amsterdam Netherlands Netherlands Active 3,3,4,4,4-pentafluorobut-1-ene 206-775-3 374-27-6 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 2,2,3,3,4,4,4-heptafluorobutan-1-ol 206-782-1 375-01-9 - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane 206-788-4 375-50-8 - View substance registered dossier
Dyneon GmbH Industrieparkstrasse 1 84508 Burgkirchen a. d. Alz Germany Germany Active 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane 206-788-4 375-50-8 2017 View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane 206-788-4 375-50-8 2018; 2019 View substance registered dossier
TSE, OR for Tosoh Finechem Rembrandt Tower Amstelplein 1 1096 HA Amsterdam Netherlands Netherlands Active 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane 206-788-4 375-50-8 2020 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride 206-792-6 375-72-4 2016 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride 206-792-6 375-72-4 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride 206-792-6 375-72-4 - View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride 206-792-6 375-72-4 2019 View substance registered dossier
Momentive Performance Materials GmbH Chempark Building V7 51368 Leverkusen NRW Germany Germany Active 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid 206-793-1 375-73-5 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 1,6-diiodoperfluorohexane 206-794-7 375-80-4 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active Betamethasone 206-825-4 378-44-9 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Betamethasone 206-825-4 378-44-9 - View substance registered dossier
GlaxoSmithKline Services Unlimited 980 Great Western Road TW8 9GS Brentford Middlesex United Kingdom United Kingdom No longer Valid Betamethasone 206-825-4 378-44-9 2021 View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active Betamethasone 206-825-4 378-44-9 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Betamethasone 206-825-4 378-44-9 2012 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active Betamethasone 206-825-4 378-44-9 - View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture Betamethasone 206-825-4 378-44-9 2018 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Difluoroacetic acid 206-839-0 381-73-7 2013; 2018 View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 3,3,3-trifluoro-2-(trifluoromethyl)propene 206-840-6 382-10-5 - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 2,2,3,3,5,5,6,6-octafluoro-4-(trifluoromethyl)morpholine 206-841-1 382-28-5 2013 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Chematek s.p.a. Piazzale Libia, 1 20135 Milano Lombardia Italy Italy Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Chr. Olesen ChemPharm GmbH Gustav-Becker-Strasse 20B 21218 Seevetal Germany Germany Active Ethyl trifluoroacetate 206-851-6 383-63-1 - View substance registered dossier
Agro-Chemie Ltd. Bányalég str. 47-59. 1225 Budapest Hungary Hungary Active 2,6-difluorobenzoic acid 206-856-3 385-00-2 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 4-nitro-3-(trifluoromethyl)aniline 206-884-6 393-11-3 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-nitro-3-(trifluoromethyl)aniline 206-884-6 393-11-3 2018 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 4-bromo-α,α,α-trifluoro-m-toluidine 206-885-1 393-36-2 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2-fluorobenzoyl chloride 206-887-2 393-52-2 - View substance registered dossier
PTC Therapeutics International Limited 5th Floor, 3 Grand Canal Plaza Grand Canal Street Upper D04 EE70 Dublin 4 Dublin Ireland Ireland Active 2-fluorobenzoyl chloride 206-887-2 393-52-2 - View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 2-fluorobenzoyl chloride 206-887-2 393-52-2 2019 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 2-fluorobenzoyl chloride 206-887-2 393-52-2 - View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 4-chloro-3,5-dinitro-α,α,α-trifluorotoluene 206-889-3 393-75-9 2019 View substance registered dossier
Finchimica S.p.A. Via Lazio 13, 25025 Manerbio (BS) Italy Italy Active 4-chloro-3,5-dinitro-α,α,α-trifluorotoluene 206-889-3 393-75-9 - View substance registered dossier
Solvay Fluor GmbH Hans-Boeckler-Allee 20 30173 HANNOVER Germany Germany Active Isopropyl trifluoroacetate 206-922-1 400-38-4 - View substance registered dossier
Vinyl Kereskedelmi és Szolgáltató Kft. Adler Károly 19. 3524 Miskolc Hungary Hungary Active α,α,α,3-tetrafluorotoluene 206-933-1 401-80-9 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active α,α,α-trifluoro-3,5-dinitrotoluene 206-935-2 401-99-0 2020 View substance registered dossier

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