Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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First published date:
Last update date:
Substance data
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Uses and exposure
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Details
(2,4-dibromophenyl)methanol
613-974-2 666747-06-4 No longer Valid Intermediate Joint No longer valid 29-11-2018 View substance registered dossier
(2,4-Difluorophenyl)(4-Fluorophenyl)methanone
813-638-7 80512-44-3 Active Intermediate Individual Intermediate use only 23-01-2018 View substance registered dossier
(2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate
605-404-6 16535-55-0 Active Full Joint ≥ 0 to < 10 tonnes 30-07-2019 View substance registered dossier
(2,5-dichloropentyl)ammonium chloride
263-758-3 62922-45-6 Active Intermediate Joint Intermediate use only 27-07-2018 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active Full Joint ≥ 10 to < 100 tonnes 14-01-2021 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
433-520-5 82911-69-1 Active Intermediate Joint Intermediate use only 06-03-2020 View substance registered dossier
(2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
433-520-5 82911-69-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(2,6-xylyloxy) acetic acid
430-910-7 13335-71-2 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bromide
404-940-6 86608-70-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1)
941-991-8 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate
442-300-8 - Active Full Joint ≥ 100 to < 1 000 tonnes 24-11-2020 View substance registered dossier
(2-(aminomethyl)phenyl)acetylchloride hydrochloride
417-410-4 61807-67-8 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(2-(methylamino)pyridin-3-yl)methyl N-(tert-butoxycabonyl)-N-methylglycinate
928-404-0 1180002-01-0 Active Intermediate Individual Intermediate use only 12-06-2018 View substance registered dossier
(2-bromo-5-fluorophenyl)methanol
606-492-9 202865-66-5 Cease Manufacture Intermediate Individual Cease manufacture 23-05-2016 View substance registered dossier
(2-bromophenyl)acetonitrile
243-091-4 19472-74-3 Active Intermediate Joint Intermediate use only 24-05-2018 View substance registered dossier
(2-butoxyethoxy)acetic acid
451-650-0 - Active NONS Individual Tonnage data confidential 10-12-2010 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - No longer Valid Intermediate Individual No longer valid 17-12-2010 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - Active Intermediate Joint Intermediate use only 22-11-2010 View substance registered dossier
(2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone
444-800-1 141645-23-0 Active Intermediate Individual Intermediate use only 22-11-2010 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone
217-773-7 1951-26-4 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone
257-959-5 52490-15-0 Active Intermediate Joint Intermediate use only 14-12-2018 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
280-851-4 83790-87-8 Active Intermediate Joint Intermediate use only 27-04-2018 View substance registered dossier
(2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride
618-106-6 88046-01-9 Active Intermediate Individual Intermediate use only 26-01-2011 View substance registered dossier
(2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride
618-106-6 88046-01-9 Active Intermediate Joint Intermediate use only 07-05-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Wychem Limited Bury Road CB8 8YN Stradishall Suffolk United Kingdom United Kingdom No longer Valid (2,4-dibromophenyl)methanol 613-974-2 666747-06-4 2021 View substance registered dossier
Stewardship Chemicals 40 Długosza 67 43-188 Orzesze Poland Poland Active (2,4-Difluorophenyl)(4-Fluorophenyl)methanone 813-638-7 80512-44-3 - View substance registered dossier
Agfa-Gevaert N.V. Septestraat 27 2640 Mortsel Belgium Belgium Active (2,4-dioxo-1,3-benzoxazin-7-yl) ethyl carbonate 605-404-6 16535-55-0 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2021 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2011; 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 2010; 2013; 2020 View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A. Industrial area of Patras, Building block 1 25018 Patras Greece Greece Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Cease Manufacture (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2,6-xylyloxy) acetic acid 430-910-7 13335-71-2 2011; 2018 View substance registered dossier
ALBEMARLE CHEMICALS S.A.S. Etang de la Gafette 13521 PORT-DE-BOUC CEDEX France France Active (2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bromide 404-940-6 86608-70-0 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1) 941-991-8 - - View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2015 View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2014; 2016; 2017 View substance registered dossier
IGM Resins Ltd c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom United Kingdom No longer Valid (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2021 View substance registered dossier
WSP UK Ltd. WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom United Kingdom No longer Valid (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2021 View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2-(aminomethyl)phenyl)acetylchloride hydrochloride 417-410-4 61807-67-8 - View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active (2-(aminomethyl)phenyl)acetylchloride hydrochloride 417-410-4 61807-67-8 - View substance registered dossier
[Confidential] - - - (2-(methylamino)pyridin-3-yl)methyl N-(tert-butoxycabonyl)-N-methylglycinate 928-404-0 1180002-01-0 - View substance registered dossier
[Confidential] - - - (2-bromo-5-fluorophenyl)methanol 606-492-9 202865-66-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
Kao Chemicals GmbH Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany Germany Active (2-butoxyethoxy)acetic acid 451-650-0 - 2010 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2010 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2019 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone 444-800-1 141645-23-0 2010 View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 2017 View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017; 2018 View substance registered dossier
Asambly Europe Company Limited Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland Ireland Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone 280-851-4 83790-87-8 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride 618-106-6 88046-01-9 2011 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride 618-106-6 88046-01-9 2020 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride 618-106-6 88046-01-9 - View substance registered dossier

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