Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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Substance data
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Details
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
700-141-4 117570-53-3 Cease Manufacture Intermediate Individual Cease manufacture 22-06-2010 View substance registered dossier
(5α)-Androsta-2,16-dien-17-yl acetate
610-545-1 50588-42-6 Cease Manufacture Full Individual Cease manufacture 21-05-2015 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt
439-350-8 - Cease Manufacture NONS Individual Cease manufacture 22-12-2010 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
600-507-2 103980-44-5 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
606-382-0 197897-11-3 Cease Manufacture Intermediate Individual Cease manufacture 20-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
617-065-1 80370-59-8 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
423-260-0 100988-63-4 Cease Manufacture NONS Individual Cease manufacture 29-10-2012 View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
619-847-8 111298-82-9 Cease Manufacture Intermediate Individual Cease manufacture 26-03-2009 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Cease Manufacture Full Joint Cease manufacture 03-05-2018 View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate
436-000-6 159010-67-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate
442-520-4 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Joint Cease manufacture 14-12-2011 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Individual Cease manufacture 31-08-2011 View substance registered dossier
(C12-C14)tert-alkylammonium methylphosphonate
404-750-3 119415-07-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(chloromethyl)bis(4-fluorophenyl)methylsilane
401-200-4 85491-26-5 Cease Manufacture Full Joint Cease manufacture 29-10-2012 View substance registered dossier
(E)-1,4-dibromobut-2-ene
212-472-7 821-06-7 Cease Manufacture Intermediate Joint Cease manufacture 18-05-2018 View substance registered dossier
(E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal
410-980-5 112704-51-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(E)-methyl 2-acetyloct-2-enoate
807-427-9 228114-02-1 Cease Manufacture Intermediate Joint Cease manufacture 16-10-2014 View substance registered dossier
(E,Z)-2,6-dimethylocta-2,4,6-triene
230-603-6 7216-56-0 Cease Manufacture Full Joint Cease manufacture 17-04-2018 View substance registered dossier
(Phenylethyl)-propylpyrandion
448-120-6 - Cease Manufacture NONS Individual Cease manufacture 14-06-2012 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid
700-307-6 52950-19-3 Cease Manufacture Intermediate Individual Cease manufacture 27-11-2009 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Cease Manufacture (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid 700-141-4 117570-53-3 2015 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (5α)-Androsta-2,16-dien-17-yl acetate 610-545-1 50588-42-6 2019 View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt 439-350-8 - 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride 600-507-2 103980-44-5 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide 606-382-0 197897-11-3 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 617-065-1 80370-59-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide 423-260-0 100988-63-4 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 619-847-8 111298-82-9 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 2020 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture (Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate 436-000-6 159010-67-0 2017 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2018 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2015 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Cease Manufacture (C12-C14)tert-alkylammonium methylphosphonate 404-750-3 119415-07-5 2018 View substance registered dossier
[Confidential] - - - (chloromethyl)bis(4-fluorophenyl)methylsilane 401-200-4 85491-26-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2016 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2017 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2015 View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2021 View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Cease Manufacture (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal 410-980-5 112704-51-5 2018 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture (E)-methyl 2-acetyloct-2-enoate 807-427-9 228114-02-1 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (E,Z)-2,6-dimethylocta-2,4,6-triene 230-603-6 7216-56-0 2021 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture (Phenylethyl)-propylpyrandion 448-120-6 - 2015 View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid 700-307-6 52950-19-3 2019 View substance registered dossier

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