Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
No results were found
Details
α-phenyl-1H-benzimidazole-2-methanol
200-073-0 50-97-5 Active Full Joint ≥ 10 to < 100 tonnes 28-06-2019 View substance registered dossier
Ephedrine hydrochloride
200-074-6 50-98-6 Active Intermediate Joint Intermediate use only 08-11-2018 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 No longer Valid Full Individual No longer valid 02-07-2013 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 Active Full Joint Tonnage data confidential 03-02-2020 View substance registered dossier
Procaine hydrochloride
200-077-2 51-05-8 Active Intermediate Joint Intermediate use only 02-07-2018 View substance registered dossier
Benzimidazole
200-081-4 51-17-2 Active Full Joint ≥ 10 to < 100 tonnes 04-01-2019 View substance registered dossier
Fluorouracil
200-085-6 51-21-8 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2,4-dinitrophenol
200-087-7 51-28-5 Active Full Joint ≥ 100 to < 1 000 tonnes 18-03-2021 View substance registered dossier
Hyoscine
200-090-3 51-34-3 Active Full Joint ≥ 10 to < 100 tonnes 31-08-2017 View substance registered dossier
L-4-hydroxyproline
200-091-9 51-35-4 Active Full Joint ≥ 10 to < 100 tonnes 25-06-2021 View substance registered dossier
L-4-hydroxyproline
200-091-9 51-35-4 Active Intermediate Joint Intermediate use only 03-05-2018 View substance registered dossier
3,5-dichlorobenzoic acid
200-092-4 51-36-5 Active Intermediate Joint Intermediate use only 20-09-2019 View substance registered dossier
DL-thyroxin
200-101-1 51-48-9 Active Full Individual ≥ 1 to < 10 tonnes 10-09-2021 View substance registered dossier
Dexamphetamine
200-112-1 51-64-9 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
4-(2-aminoethyl)phenol
200-115-8 51-67-2 Active Full Joint ≥ 1 to < 10 tonnes 06-03-2018 View substance registered dossier
4-(2-aminoethyl)phenol
200-115-8 51-67-2 Active Intermediate Joint Intermediate use only 05-01-2016 View substance registered dossier
N,N,N',N'-tetramethylmethylenediamine
200-124-7 51-80-9 Active Intermediate Joint Intermediate use only 29-10-2014 View substance registered dossier
Morphine hydrochloride
200-136-2 52-26-6 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
Bronopol
200-143-0 52-51-7 Active Full Joint ≥ 100 to < 1 000 tonnes 12-03-2020 View substance registered dossier
Cysteine hydrochloride
200-157-7 52-89-1 Active Full Joint ≥ 1 000 to < 10 000 tonnes 01-09-2021 View substance registered dossier
L-cysteine
200-158-2 52-90-4 Active Full Joint ≥ 10 to < 100 tonnes 10-11-2020 View substance registered dossier
L-cysteine
200-158-2 52-90-4 Active Intermediate Joint Intermediate use only 30-01-2019 View substance registered dossier
Estrone
200-164-5 53-16-7 Active Full Joint ≥ 10 to < 100 tonnes 24-08-2021 View substance registered dossier
Methylprednisolone 21-acetate
200-171-3 53-36-1 Active Intermediate Joint Intermediate use only 30-10-2017 View substance registered dossier
Prasterone
200-175-5 53-43-0 Active Intermediate Joint Intermediate use only 08-07-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active α-phenyl-1H-benzimidazole-2-methanol 200-073-0 50-97-5 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Ephedrine hydrochloride 200-074-6 50-98-6 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Ephedrine hydrochloride 200-074-6 50-98-6 2018 View substance registered dossier
Copyr S.p.A. Via G. Stephenson 73 20157 Milano Italy Italy No longer Valid 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2017 View substance registered dossier
ENDURA S.p.A. Viale Pietramellara, 5 40121 Bologna Italy Italy Active 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2014; 2020 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Procaine hydrochloride 200-077-2 51-05-8 2017; 2018 View substance registered dossier
ANTIBIOTICOS DE LEON S.L. Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Benzimidazole 200-081-4 51-17-2 2017; 2018 View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active Benzimidazole 200-081-4 51-17-2 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Fluorouracil 200-085-6 51-21-8 - View substance registered dossier
JSC Grindeks Krustpils street 53 LV-1057 Riga Latvia Latvia Active Fluorouracil 200-085-6 51-21-8 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Fluorouracil 200-085-6 51-21-8 2012 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 2,4-dinitrophenol 200-087-7 51-28-5 - View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active Hyoscine 200-090-3 51-34-3 2017 View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Kyowa Hakko Europe GmbH Am Wehrhahn 50 40211 Düsseldorf Germany Germany Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Life Technologies Europe BV Kwartsweg 2 2665 NN Bleiswijk Netherlands Netherlands Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Global Life Sciences Solutions Austria GmbH & Co KG Kremplstraße 5 4061 Pasching Austria Austria Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 3,5-dichlorobenzoic acid 200-092-4 51-36-5 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Active DL-thyroxin 200-101-1 51-48-9 2021 View substance registered dossier
SYNTHEXIM 1 Quai d'Amérique 62 100 calais France France Active Dexamphetamine 200-112-1 51-64-9 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-(2-aminoethyl)phenol 200-115-8 51-67-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-(2-aminoethyl)phenol 200-115-8 51-67-2 - View substance registered dossier
Taminco BV Pantserschipstraat 207 9000 Gent Belgium Belgium Active N,N,N',N'-tetramethylmethylenediamine 200-124-7 51-80-9 - View substance registered dossier
[Confidential] - - - Morphine hydrochloride 200-136-2 52-26-6 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Bronopol 200-143-0 52-51-7 2019 View substance registered dossier
Nutrition & Biosciences Netherlands B.V. Willem Einthovenstraat 4 2342 BH Oegstgeest Netherlands Netherlands Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
THOR GmbH Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany Germany Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
THOR ESPECIALIDADES, S.A. AVDA. DE LA INDUSTRIA, 1 - POL. IND. EL PLA 08297 CASTELLGALI BARCELONA Spain Spain Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
B-Lands Consulting (811703-4) OR of Wuhan Grand hoyo Co, . Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 2016; 2017; 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
B-Lands Consulting (811700-5) OR of Shine Star (Hubei) Biological Engineering Co., Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture Cysteine hydrochloride 200-157-7 52-89-1 2019 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
SAFC Biosciences Limited Smeaton Road, West Potway SP10 3LF Andover United Kingdom United Kingdom No longer Valid Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
Life Technologies Europe BV Kwartsweg 2 2665 NN Bleiswijk Netherlands Netherlands Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
CJ Europe GmbH Unterschweinstiege 2-14 60549 Frankfurt am Main Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid L-cysteine 200-158-2 52-90-4 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active L-cysteine 200-158-2 52-90-4 2016 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
B-Lands Consulting (811703-4) OR of Wuhan Grand hoyo Co, . Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid L-cysteine 200-158-2 52-90-4 2021 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active L-cysteine 200-158-2 52-90-4 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active Estrone 200-164-5 53-16-7 2011; 2012; 2017 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Estrone 200-164-5 53-16-7 2011; 2017 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active Estrone 200-164-5 53-16-7 2011 View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Estrone 200-164-5 53-16-7 - View substance registered dossier
[Confidential] - - - Estrone 200-164-5 53-16-7 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Estrone 200-164-5 53-16-7 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Methylprednisolone 21-acetate 200-171-3 53-36-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Prasterone 200-175-5 53-43-0 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active Prasterone 200-175-5 53-43-0 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Prasterone 200-175-5 53-43-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Prasterone 200-175-5 53-43-0 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active Prasterone 200-175-5 53-43-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany No longer Valid Prasterone 200-175-5 53-43-0 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active Prasterone 200-175-5 53-43-0 2019 View substance registered dossier

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