Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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Substance data
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Details
Diisononylamine
249-029-2 28454-70-8 Active Intermediate Individual Intermediate use only 23-02-2016 View substance registered dossier
Diisopentyl phthalate
210-088-4 605-50-5 Cease Manufacture Full Individual Cease manufacture 25-03-2021 View substance registered dossier
Diisopropanolammonium p-toluenesulphonate
603-351-3 129678-02-0 Active Full Individual ≥ 1 to < 10 tonnes 05-05-2018 View substance registered dossier
Dilithium 7-acetamido-1-hydroxy-2-(4-((2-sulfonatooxy)ethylsulfonyl)phenylazo)naphthalene-3-sulfonate
401-010-1 - Cease Manufacture NONS Individual Cease manufacture 20-12-2010 View substance registered dossier
Dilithium disodium (5,5'-diamino-(μ-4,4'-dihydroxy-1:2-κ-2,O4,O4',-3,3'-[3,3'-dihydroxy-1:2-κ-2-O3,O3'-biphenyl-4,4'-ylenebisazo-1:2-(N3,N4-η:N3',N4'-η)]-dinaphthalene-2,7-disulfonato(8)))dicuprate(2-)
BLUE GS 1259 R5
407-230-4 126637-70-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dilutetium oxide silicate
235-337-4 12168-86-4 Active Full Individual ≥ 1 to < 10 tonnes 07-05-2019 View substance registered dossier
DIMETHYL
428-270-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Dimethyl (2-acetoxyethyl)phosphonate
254-301-9 39118-50-8 Active Intermediate Individual Intermediate use only 09-11-2012 View substance registered dossier
dimethyl (2S)-2-hydroxysuccinate
432-310-0 617-55-0 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Dimethyl 2,2'-[(4-methylbenzene-1,2-diyl)bis(oxy)]diacetate
700-270-6 52589-39-6 Active Intermediate Individual Intermediate use only 10-02-2009 View substance registered dossier
Dimethyl 3,3'-(N-(4-(4-bromo-2,6-dicyanophenylazo)-3-hydroxyphenyl)imino)dipropionate
407-310-9 122630-55-1 Active NONS Individual Tonnage data confidential 18-07-2011 View substance registered dossier
Dimethyl 3-oxoglutarate
217-385-8 1830-54-2 Active Intermediate Individual Intermediate use only 03-05-2013 View substance registered dossier
dimethyl 5-methylpyridine-2,3-dicarboxylate
601-161-5 112110-16-4 Active Intermediate Individual Intermediate use only 10-07-2014 View substance registered dossier
Dimethyl disulphide
210-871-0 624-92-0 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
Dimethyl maleate
210-848-5 624-48-6 Active Intermediate Individual Intermediate use only 09-06-2010 View substance registered dossier
Dimethyl malonate
203-597-8 108-59-8 Active Intermediate Individual Intermediate use only 16-04-2012 View substance registered dossier
Dimethyl methylphosphonate
212-052-3 756-79-6 Active Intermediate Individual Intermediate use only 26-08-2010 View substance registered dossier
Dimethyl phthalate
205-011-6 131-11-3 No longer Valid Full Individual No longer valid 18-12-2015 View substance registered dossier
Dimethyl sebacate
203-431-4 106-79-6 Active Intermediate Individual Intermediate use only 29-05-2013 View substance registered dossier
Dimethyl succinate
203-419-9 106-65-0 Active Intermediate Individual Intermediate use only 08-03-2012 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 13-06-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 07-01-2015 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Cease Manufacture Intermediate Individual Cease manufacture 10-12-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Cease Manufacture Intermediate Individual Cease manufacture 10-12-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 16-12-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 19-10-2012 View substance registered dossier
dimethyl(phenyl)sulfanium perfluorobutanesulfonate 452-310-4 220133-51-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
dimethyl-1-{[2-methoxy-5-(2-methyl-butoxycarbonyl)phenylcarbamoyl]-[2-octadecyl-1,1-dioxo-1,2,4-benzothiadiazin-3-yl]methyl} imidazole-4,5-dicarboxylate
443-910-7 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Dimethylamine-borane (1:1)
200-823-7 74-94-2 Active Full Individual Tonnage data confidential 06-04-2018 View substance registered dossier
Dimethylcarbamoyl chloride
201-208-6 79-44-7 Active Intermediate Individual Intermediate use only 01-04-2011 View substance registered dossier
Dimethylcyclopropane-1,1-dicarboxylate
414-240-2 6914-71-2 Active Intermediate Individual Intermediate use only 19-10-2010 View substance registered dossier
dinotefuran (ISO); 1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine
605-399-0 165252-70-0 Active Full Individual ≥ 10 to < 100 tonnes 10-03-2020 View substance registered dossier
Diolat
439-580-9 - Active Intermediate Individual Intermediate use only 24-09-2010 View substance registered dossier
Dipentaerythritol hexaesters of 3,5,5-trimethylhexanoic, n-decanoic, n-octanoic, and n-pentanoic acids
701-334-6 - Active Full Individual ≥ 0 to < 10 tonnes 20-04-2020 View substance registered dossier
diphenoxymethylenecyanamide
427-300-8 79463-77-7 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Diphenyl (methylenedi-4,1-phenylene)-dicarbamate
202-963-4 101-65-5 Active Intermediate Individual Intermediate use only 11-05-2018 View substance registered dossier
Diphenyl ether
202-981-2 101-84-8 Active Intermediate Individual Intermediate use only 07-10-2016 View substance registered dossier
Diphenylacetic acid
204-185-0 117-34-0 Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
Diphenylamine
204-539-4 122-39-4 Active Full Individual ≥ 1 to < 10 tonnes 09-06-2018 View substance registered dossier
Diphenylamine
204-539-4 122-39-4 Active Intermediate Individual Intermediate use only 05-01-2021 View substance registered dossier
Diphenylphosphinic chloride
216-107-2 1499-21-4 Active Intermediate Individual Intermediate use only 31-01-2019 View substance registered dossier
Diphosphoric acid, P,P,P',P'-tetrakis(phenylmethyl) ester
628-817-3 990-91-0 Active Intermediate Individual Intermediate use only 03-02-2017 View substance registered dossier
Dipotassium (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioate
700-601-4 1333869-99-0 Active Intermediate Individual Intermediate use only 28-07-2011 View substance registered dossier
Dipraseodymium dizirconium heptaoxide
832-253-5 12165-18-3 Active Full Individual ≥ 1 to < 10 tonnes 21-11-2018 View substance registered dossier
Dipropylmalonic acid
216-664-1 1636-27-7 Active Intermediate Individual Intermediate use only 27-09-2011 View substance registered dossier
Direct Yellow 169
407-250-3 - Cease Manufacture Full Individual Cease manufacture 20-04-2012 View substance registered dossier
DISODIUM (2S,3R)-2-HYDROXY-3-ISOBUTYLSUCCINATE
428-800-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
disodium (E)-1,2-bis-(4-(4-methylamino-6-(4-methylcarbamoylphenylamino)-1,3,5-triazin-2-ylamino)phenyl-2-sulfonato)ethene
427-310-2 180850-95-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Disodium 1-amino-4-(2-(5-chloro-6-fluoro-pyrimidin-4-ylamino-methyl)-4-methyl-6-sulfo-phenylamino)-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonate
414-040-5 149530-93-8 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
disodium 2,4-dihydroxy-5-[(2-hydroxy-3-nitro-5-sulphonato-phenyl)azo]benzoate, reaction products with chromium triacetate
946-871-9 - Active Full Individual ≥ 1 to < 10 tonnes 31-01-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Diisononylamine 249-029-2 28454-70-8 - View substance registered dossier
EURENCO Bofors AB Kontorsvägen 6 SE-691 86 Karlskoga Sweden Sweden Cease Manufacture Diisopentyl phthalate 210-088-4 605-50-5 2021 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active Diisopropanolammonium p-toluenesulphonate 603-351-3 129678-02-0 - View substance registered dossier
CFB Chemische Fabrik Brunsbüttel GmbH Kühlturmstrasse 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Cease Manufacture Dilithium 7-acetamido-1-hydroxy-2-(4-((2-sulfonatooxy)ethylsulfonyl)phenylazo)naphthalene-3-sulfonate 401-010-1 - 2016 View substance registered dossier
Clariant Production UK Ltd Clariant House, Unit 2 Rawdon Park LS19 7BA Yeadon Leeds United Kingdom United Kingdom Active Dilithium disodium (5,5'-diamino-(μ-4,4'-dihydroxy-1:2-κ-2,O4,O4',-3,3'-[3,3'-dihydroxy-1:2-κ-2-O3,O3'-biphenyl-4,4'-ylenebisazo-1:2-(N3,N4-η:N3',N4'-η)]-dinaphthalene-2,7-disulfonato(8)))dicuprate(2-) 407-230-4 126637-70-5 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active Dilutetium oxide silicate 235-337-4 12168-86-4 2018; 2019 View substance registered dossier
- - - - DIMETHYL 428-270-9 - - View substance registered dossier
Curia Germany GmbH Industrial Park Hoechst Building D569 65926 Frankfurt Germany Germany Active Dimethyl (2-acetoxyethyl)phosphonate 254-301-9 39118-50-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active dimethyl (2S)-2-hydroxysuccinate 432-310-0 617-55-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active Dimethyl 2,2'-[(4-methylbenzene-1,2-diyl)bis(oxy)]diacetate 700-270-6 52589-39-6 2009 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active Dimethyl 3,3'-(N-(4-(4-bromo-2,6-dicyanophenylazo)-3-hydroxyphenyl)imino)dipropionate 407-310-9 122630-55-1 2011 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active Dimethyl 3-oxoglutarate 217-385-8 1830-54-2 - View substance registered dossier
[Confidential] - - - dimethyl 5-methylpyridine-2,3-dicarboxylate 601-161-5 112110-16-4 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland Ireland Active Dimethyl disulphide 210-871-0 624-92-0 2012 View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Dimethyl maleate 210-848-5 624-48-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Dimethyl malonate 203-597-8 108-59-8 - View substance registered dossier
THOR GmbH Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany Germany Active Dimethyl methylphosphonate 212-052-3 756-79-6 - View substance registered dossier
Koopman International B.V. Distelweg 88 1031 HH Amsterdam Netherlands Netherlands No longer Valid Dimethyl phthalate 205-011-6 131-11-3 2017 View substance registered dossier
3V Sigma S.p.A Torquato Tasso 58 24121 Bergamo Italy Italy Active Dimethyl sebacate 203-431-4 106-79-6 - View substance registered dossier
Only representative (No publishable name) - - Active Dimethyl succinate 203-419-9 106-65-0 - View substance registered dossier
CHT Germany GmbH Bismarckstr. 102 72072 Tuebingen Germany Germany Active Dimethyl sulphate 201-058-1 77-78-1 - View substance registered dossier
OQEMA LIMITED (IRELAND) Millienium House Athlone Road N39YW40 Ballymahon, Co Longford Ireland Ireland Active Dimethyl sulphate 201-058-1 77-78-1 2015 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture Dimethyl sulphate 201-058-1 77-78-1 2019 View substance registered dossier
[Confidential] - - - Dimethyl sulphate 201-058-1 77-78-1 - View substance registered dossier
AAKO BV Arnhemseweg 87 3832 GK Leusden Netherlands Netherlands Active Dimethyl sulphate 201-058-1 77-78-1 2014 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Dimethyl sulphate 201-058-1 77-78-1 2012 View substance registered dossier
- - - - dimethyl(phenyl)sulfanium perfluorobutanesulfonate 452-310-4 220133-51-7 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture dimethyl-1-{[2-methoxy-5-(2-methyl-butoxycarbonyl)phenylcarbamoyl]-[2-octadecyl-1,1-dioxo-1,2,4-benzothiadiazin-3-yl]methyl} imidazole-4,5-dicarboxylate 443-910-7 - 2020 View substance registered dossier
[Confidential] - - - Dimethylamine-borane (1:1) 200-823-7 74-94-2 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active Dimethylcarbamoyl chloride 201-208-6 79-44-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Dimethylcyclopropane-1,1-dicarboxylate 414-240-2 6914-71-2 2010 View substance registered dossier
LKC Chem-Regs Ltd. Marine House Clanwilliam Place 2 Dublin Ireland Ireland Active dinotefuran (ISO); 1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine 605-399-0 165252-70-0 2018; 2020 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active Diolat 439-580-9 - 2010 View substance registered dossier
Zschimmer & Schwarz GmbH & Co KG Max-Schwarz-Str. 3-5 56112 Lahnstein Germany Germany Active Dipentaerythritol hexaesters of 3,5,5-trimethylhexanoic, n-decanoic, n-octanoic, and n-pentanoic acids 701-334-6 - 2020 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture diphenoxymethylenecyanamide 427-300-8 79463-77-7 2015 View substance registered dossier
Schirm GmbH Geschwister-Scholl-Strasse 127 D-39218 Schönebeck Germany Germany Active Diphenyl (methylenedi-4,1-phenylene)-dicarbamate 202-963-4 101-65-5 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Diphenyl ether 202-981-2 101-84-8 - View substance registered dossier
Katwijk Chemie BV Snijderstraat 6 Steenbakkerstraat 26 2222 BA Katwijk ZH Netherlands Netherlands Active Diphenylacetic acid 204-185-0 117-34-0 - View substance registered dossier
CN ROMARM SA - SC UZINA MECANICA CUGIR SA Str. 21 Decembrie 1989 nr.1 515600 Bucuresti Romania Romania Active Diphenylamine 204-539-4 122-39-4 2018 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Diphenylamine 204-539-4 122-39-4 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active Diphenylphosphinic chloride 216-107-2 1499-21-4 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active Diphosphoric acid, P,P,P',P'-tetrakis(phenylmethyl) ester 628-817-3 990-91-0 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Dipotassium (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioate 700-601-4 1333869-99-0 2011 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active Dipraseodymium dizirconium heptaoxide 832-253-5 12165-18-3 - View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active Dipropylmalonic acid 216-664-1 1636-27-7 - View substance registered dossier
BASF Grenzach GmbH Köchlinstr. 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture Direct Yellow 169 407-250-3 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active DISODIUM (2S,3R)-2-HYDROXY-3-ISOBUTYLSUCCINATE 428-800-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active disodium (E)-1,2-bis-(4-(4-methylamino-6-(4-methylcarbamoylphenylamino)-1,3,5-triazin-2-ylamino)phenyl-2-sulfonato)ethene 427-310-2 180850-95-7 - View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Cease Manufacture Disodium 1-amino-4-(2-(5-chloro-6-fluoro-pyrimidin-4-ylamino-methyl)-4-methyl-6-sulfo-phenylamino)-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonate 414-040-5 149530-93-8 2012 View substance registered dossier
Clariant SE - CH30 Am Unisyspark 1 65843 Sulzbach am Taunus Germany Germany Active disodium 2,4-dihydroxy-5-[(2-hydroxy-3-nitro-5-sulphonato-phenyl)azo]benzoate, reaction products with chromium triacetate 946-871-9 - - View substance registered dossier

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