Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 20,001 - 20,100 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	Active	Intermediate	Joint	Intermediate use only	15-05-2023	View substance registered dossier
(3aS,9aS,9bS)-3-hydroxy-3a-methyl-6-(3-oxobutyl)-1,2,3,3a,4,5,8,9,9a,9b-decahydro-7H-cyclopenta[a]naphthalen-7-one	609-999-3	4222-76-8	Active	Intermediate	Joint	Intermediate use only	07-02-2022	View substance registered dossier
Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-	610-008-1	42267-27-6	Active	Intermediate	Joint	Intermediate use only	13-04-2018	View substance registered dossier
2-methylprop-1-ene, pentamer	610-010-2	42278-27-3	Active	Intermediate	Joint	Intermediate use only	21-01-2022	View substance registered dossier
2,7-dihydroxyfluoren-9-one	610-035-9	42523-29-5	Active	Intermediate	Joint	Intermediate use only	03-07-2018	View substance registered dossier
6-Bromo-1-hexanol	610-072-0	4286-55-9	Active	Intermediate	Individual	Intermediate use only	02-05-2016	View substance registered dossier
1-Naphthalenemethanamine, a-methyl-	610-076-2	42882-31-5	Active	Intermediate	Joint	Intermediate use only	10-01-2018	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	11-06-2020	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	10-10-2016	View substance registered dossier
Benzenesulfonic acid, 2-amino-5-((2-(sulfooxy)ethyl)sulfonyl)-	610-097-7	42986-22-1	Active	Intermediate	Joint	Intermediate use only	22-03-2019	View substance registered dossier
5’,5’’’’-(1,1,1-trifluoropropane-2,2-diyl)bis(1,1’:3’,1’’-terphenyl-2’-ol)	610-104-3	43100-47-6	Active	Full	Joint	≥ 1 to < 10 tonnes	26-11-2015	View substance registered dossier
(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	Active	Intermediate	Joint	Intermediate use only	13-10-2021	View substance registered dossier
6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	Active	Intermediate	Joint	Intermediate use only	16-07-2020	View substance registered dossier
6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	Active	Intermediate	Joint	Intermediate use only	09-07-2019	View substance registered dossier
2-[benzyl-[1-(4-methoxyphenyl)propan-2-yl]amino]-1-(3-nitro-4-phenylmethoxyphenyl)ethanone	610-116-9	43229-66-9	Active	Intermediate	Joint	Intermediate use only	09-07-2019	View substance registered dossier
[(2S,3R,5S)-3-acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate	610-122-1	433733-94-9	No longer Valid	Full	Joint	No longer valid	14-01-2020	View substance registered dossier
amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	Active	Full	Joint	≥ 10 000 to < 100 000 tonnes	26-04-2023	View substance registered dossier
4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl) benzenesulfonic acid	610-141-5	437717-43-6	Active	Full	Individual	≥ 0 to < 10 tonnes	16-12-2013	View substance registered dossier
2,6-Difluorobenzaldehyde	610-142-0	437-81-0	Active	Intermediate	Joint	Intermediate use only	14-03-2022	View substance registered dossier
4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	06-02-2013	View substance registered dossier
triphenyl(((1r,4r)-4-((E)-prop-1-en-1-yl)cyclohexyl)methyl)phosphonium iodide	610-150-4	438193-30-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-07-2013	View substance registered dossier
2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	Active	Intermediate	Joint	Intermediate use only	30-04-2018	View substance registered dossier
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethane-1-sulfonyl chloride	610-161-4	4403-36-5	Active	Full	Joint	≥ 1 to < 10 tonnes	14-03-2019	View substance registered dossier
9H-fluorene-9,9-diyldimethanol	610-170-3	4425-93-8	Active	Intermediate	Joint	Intermediate use only	11-11-2016	View substance registered dossier
7-[2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)acetamido]-3-vinyl-cephem-4-carboxylic acid	610-178-7	443874-49-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-04-2018	View substance registered dossier
2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	Active	Intermediate	Joint	Intermediate use only	25-11-2021	View substance registered dossier
4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	Active	Intermediate	Joint	Intermediate use only	04-08-2020	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Individual	Intermediate use only	21-08-2018	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Joint	Intermediate use only	19-12-2022	View substance registered dossier
2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	Active	Intermediate	Joint	Intermediate use only	22-12-2022	View substance registered dossier
N-(5-bromo-3-methylpyridin-2-yl)-N-methylbenzamide	610-202-6	446299-80-5	Active	Full	Joint	≥ 1 to < 10 tonnes	13-12-2022	View substance registered dossier
Boronic acid, [6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-	610-203-1	446299-81-6	Active	Full	Joint	≥ 1 to < 10 tonnes	15-12-2020	View substance registered dossier
3-Quinolinecarboxylic acid, 7-[6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester	610-204-7	446299-90-7	Active	Full	Joint	≥ 1 to < 10 tonnes	02-07-2021	View substance registered dossier
N6-Benzoyladenosine	610-251-3	4546-55-8	Active	Intermediate	Joint	Intermediate use only	10-02-2022	View substance registered dossier
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
6,8-disulfanyloctanoic acid	610-288-5	462-20-4	Active	Intermediate	Joint	Intermediate use only	26-03-2021	View substance registered dossier
2-Amino-4,5-dimethyl-thiophene-3-carbonitrile	610-309-8	4651-94-9	Active	Intermediate	Individual	Intermediate use only	02-10-2012	View substance registered dossier
(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	Active	Intermediate	Joint	Intermediate use only	11-08-2017	View substance registered dossier
2,3-Difluor-1-propoxy-4-[trans-4-(trans-4-propylcyclohexyl)- cyclohexyl]-benzene	610-336-5	473257-14-6	Active	Full	Joint	≥ 1 to < 10 tonnes	13-12-2017	View substance registered dossier
4-[trans-4-(trans-4-butylcyclohexyl)-cyclohexyl]-1-ethoxy-2, 3-difluorobenzene	610-337-0	473257-15-7	Active	Full	Joint	≥ 1 to < 10 tonnes	14-12-2017	View substance registered dossier
1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	Active	Intermediate	Joint	Intermediate use only	24-05-2018	View substance registered dossier
Sodium 3-hydroxy-5-sulfanyl-1,2-thiazole-4-carboxylate	610-355-9	475112-25-5	Active	Intermediate	Joint	Intermediate use only	02-10-2017	View substance registered dossier
1,1,2,3,3-pentamethyl-5-(2-methylprop-2-en-1-yl)octahydro-4H-inden-4-one	610-371-6	476332-63-5	Active	Intermediate	Joint	Intermediate use only	07-01-2021	View substance registered dossier
Iron(1+), chloro[dimethyl 9,9-dihydroxy-3-methyl-2,4-di(2-pyridinyl-kN)-7-[(2-pyridinyl-kN)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate-kN3,kN7]-, chloride	610-388-9	478945-46-9	Active	Full	Joint	≥ 1 to < 10 tonnes	02-11-2021	View substance registered dossier
3-(3,4-dicyanophenylsulfonyl)propane-1-sulfonyl chloride	610-401-8	480427-96-1	No longer Valid	Intermediate	Individual	No longer valid	03-04-2017	View substance registered dossier
5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	Active	Intermediate	Joint	Intermediate use only	22-07-2020	View substance registered dossier
4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl	610-428-5	486406-09-1	Active	Full	Joint	≥ 0 to < 10 tonnes	24-11-2022	View substance registered dossier
(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	Active	Full	Individual	≥ 1 to < 10 tonnes	23-02-2022	View substance registered dossier
3-(3,4-Dimethoxyphenyl)propanenitrile	610-465-7	49621-56-9	Active	Full	Joint	≥ 1 to < 10 tonnes	19-03-2018	View substance registered dossier
2-Bromo-4-fluorophenol	610-467-8	496-69-5	No longer Valid	Intermediate	Joint	No longer valid	31-07-2019	View substance registered dossier
2,2-dioxo-1,2λ6-benzoxathiin-4-one	610-468-3	49670-47-5	Active	Intermediate	Joint	Intermediate use only	28-10-2016	View substance registered dossier
3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene] hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid	610-469-9	496775-61-2	Active	Intermediate	Joint	Intermediate use only	16-03-2021	View substance registered dossier
N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	Active	Full	Joint	≥ 1 to < 10 tonnes	18-10-2021	View substance registered dossier
methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	Active	Intermediate	Joint	Intermediate use only	03-05-2021	View substance registered dossier
2-(3-Chloro-2-pyridinyl)-5-oxo-3-pyrazolidinecarboxylic acid ethyl ester	610-490-3	500011-88-1	Active	Intermediate	Joint	Intermediate use only	03-12-2020	View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate	610-491-9	500011-92-7	Active	Intermediate	Joint	Intermediate use only	08-10-2020	View substance registered dossier
(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	Active	Intermediate	Joint	Intermediate use only	28-05-2018	View substance registered dossier
L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester	610-513-7	502421-44-5	Cease Manufacture	Intermediate	Individual	Cease manufacture	03-10-2011	View substance registered dossier
2-Propanol, 1-(3,5-dimethylphenoxy)-3-[(phenylmethyl)amino]-	610-515-8	502605-82-5	Active	Intermediate	Joint	Intermediate use only	12-10-2017	View substance registered dossier
2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt	610-522-6	503155-49-5	Active	Full	Joint	≥ 0 to < 10 tonnes	28-11-2020	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	Active	Intermediate	Joint	Intermediate use only	06-05-2020	View substance registered dossier
(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	Cease Manufacture	Full	Individual	Cease manufacture	21-05-2015	View substance registered dossier
2-Hydroxy-4-(trifluoromethyl)pyridine	610-554-0	50650-59-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-04-2019	View substance registered dossier
4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	Active	Intermediate	Joint	Intermediate use only	24-02-2020	View substance registered dossier
[(8R,9S,10R,13S,14S,17R)-3-ethoxy-17-ethynyl-13-methyl-2,7,8,9,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate	610-565-0	50717-99-2	Active	Full	Joint	≥ 1 to < 10 tonnes	18-12-2018	View substance registered dossier
(R)-2-acetoxy-2-phenylacetic acid	610-598-0	51019-43-3	Active	Intermediate	Joint	Intermediate use only	17-06-2015	View substance registered dossier
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-7-oxo-8-oxa-3,5-dithia-4-phosphatetradecanoate 4-oxide	610-601-5	51032-53-2	Active	Intermediate	Joint	Intermediate use only	02-05-2018	View substance registered dossier
1,2,4,9-Tetrahydrocarbazol-3-one	610-619-3	51145-61-0	Active	Intermediate	Joint	Intermediate use only	13-02-2016	View substance registered dossier
5-Brom-2-[(3,4,5-trifluorphenoxy)-difluormethyl]-1,3-difluorbenzene	610-623-5	511540-64-0	Active	Full	Joint	≥ 10 to < 100 tonnes	18-02-2021	View substance registered dossier
oils, palm, propoxylated	610-641-3	512802-65-2	Active	Full	Joint	≥ 10 to < 100 tonnes	25-01-2019	View substance registered dossier
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine	610-648-1	51322-75-9	Active	Intermediate	Joint	Intermediate use only	22-01-2018	View substance registered dossier
2-Chloro-1-(3,4-difluorophenyl)ethanone	610-651-8	51336-95-9	Active	Intermediate	Individual	Intermediate use only	07-10-2009	View substance registered dossier
Phosphonic acid, diammonium salt, monohydrate	610-672-2	51503-61-8	Active	Full	Joint	≥ 100 to < 1 000 tonnes	30-05-2018	View substance registered dossier
2-Propenoic acid, 3-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, methyl ester, hydrochloride (1:1)	610-682-7	51531-46-5	Active	Intermediate	Joint	Intermediate use only	13-03-2018	View substance registered dossier
(2E)-3-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methylprop-2-enal	610-698-4	51575-61-2	Active	Intermediate	Joint	Intermediate use only	17-07-2015	View substance registered dossier
(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	Active	Intermediate	Joint	Intermediate use only	21-02-2019	View substance registered dossier
Rifamycin, 3-amino-1,4-dideoxy-1,4-dihydro-1,4-dioxo-(9Cl)	610-723-9	51756-80-0	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	29-05-2018	View substance registered dossier
Diphenylmethyl (6R)-3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate	610-726-5	51762-51-7	Active	Intermediate	Joint	Intermediate use only	23-11-2017	View substance registered dossier
{4-[2-(Dimethylamino)ethoxy]phenyl}(phenyl)methanone	610-729-1	51777-15-2	Active	Intermediate	Joint	Intermediate use only	11-04-2018	View substance registered dossier
1-amino-2-(1-methyl-1-phenoxycarbonylamino-ethyl)-oxime	610-731-2	518047-98-8	Active	Intermediate	Joint	Intermediate use only	31-05-2017	View substance registered dossier
5-hydroxy-1-methyl-2-(1-methyl-1-phenoxycabonylamino-ethyl)-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid 4-fluorobenzylamide	610-732-8	518048-02-7	Active	Intermediate	Joint	Intermediate use only	16-03-2016	View substance registered dossier
N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide	610-733-3	518048-05-0	Active	Intermediate	Joint	Intermediate use only	09-05-2018	View substance registered dossier
5,8-Dihydro-1-naphthyl acetate	610-759-5	51927-56-1	Active	Intermediate	Individual	Intermediate use only	27-10-2017	View substance registered dossier
4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	Active	Intermediate	Joint	Intermediate use only	20-02-2019	View substance registered dossier
Nickel, compound with Titanium (1:1)	610-765-8	52013-44-2	Active	Full	Individual	≥ 1 to < 10 tonnes	22-11-2013	View substance registered dossier
2-(2-ethoxyphenoxy)ethanamine methanesulfonate	610-786-2	521300-98-1	Active	Intermediate	Joint	Intermediate use only	15-05-2018	View substance registered dossier
Potassium [(4-{2-[(5-chloro-2-methoxybenzoyl)amino]ethyl}phenyl)sulfonyl](cyclohexylamino)carbonyl]azanide	610-790-4	52169-36-5	Active	Intermediate	Joint	Intermediate use only	23-06-2022	View substance registered dossier
4-(4-chlorophenyl)-3-methyl-4-oxo-butanoic acid	610-810-1	52240-25-2	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
Ethyl-(3-hydroxypropyl)propanedioic acid	610-813-8	52250-47-2	Active	Intermediate	Joint	Intermediate use only	16-04-2020	View substance registered dossier
N-Methyl-3-sulfanylpropanamide	610-826-9	52334-99-3	Active	Intermediate	Joint	Intermediate use only	16-08-2018	View substance registered dossier
4-Cyano-2nitrobenzoic acid methyl ester	610-840-5	52449-76-0	Active	Intermediate	Joint	Intermediate use only	14-11-2017	View substance registered dossier
ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate	610-841-0	52450-32-5	Active	Intermediate	Joint	Intermediate use only	19-10-2017	View substance registered dossier
2',3,5-Trifluoro-4''-(trans-4-propylcyclohexyl)-4-trifluoromethoxy-[1,1';4',1'']terphenyl	610-847-3	524709-77-1	Active	Full	Joint	≥ 0 to < 10 tonnes	29-03-2018	View substance registered dossier
dimethyl(dipropyl)azanium;bromide	610-854-1	52509-52-1	Active	Intermediate	Joint	Intermediate use only	11-07-2019	View substance registered dossier
5-amino-3-methyl-2,4-thiophenedicarbonitrile	610-868-8	52603-48-2	Active	Full	Individual	≥ 1 to < 10 tonnes	19-11-2012	View substance registered dossier
Oxirane, 2-methyl-, oligomeric reaction products with oxirane, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1)	610-877-7	52624-57-4	Active	Intermediate	Individual	Intermediate use only	29-02-2012	View substance registered dossier
1H-1,4,7-Triazonine, octahydro-1,4,7-tris[(4-methylphenyl)sulfonyl]-	610-880-3	52667-89-7	Active	Intermediate	Joint	Intermediate use only	03-03-2021	View substance registered dossier
octan-2-yl cyanoacetate	610-886-6	52688-08-1	Active	Intermediate	Joint	Intermediate use only	22-09-2016	View substance registered dossier
octan-2-yl cyanoacetate	610-886-6	52688-08-1	Cease Manufacture	Intermediate	Individual	Cease manufacture	21-09-2011	View substance registered dossier
isobutyl (2Z)-3-aminobut-2-enoate	610-915-2	52937-90-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	11-11-2013	View substance registered dossier

Showing 20,001 - 20,100 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2023	View substance registered dossier
WeylChem Höchst GmbH	Brüningstr. 50 D-65929 Frankfurt am Main Germany	Germany	Active	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2023	View substance registered dossier
WeylChem Griesheim GmbH	Stroofstr. 27 D-65933 Frankfurt am Main Germany	Germany	Cease Manufacture	2,3,4,5-Tetrachlorobenzoyl chloride	609-997-2	42221-52-3	2019	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(3aS,9aS,9bS)-3-hydroxy-3a-methyl-6-(3-oxobutyl)-1,2,3,3a,4,5,8,9,9a,9b-decahydro-7H-cyclopenta[a]naphthalen-7-one	609-999-3	4222-76-8	2022	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	Acetamide, N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-	610-008-1	42267-27-6	-	View substance registered dossier
INEOS Manufacturing Deutschland GmbH	Alte Strasse 201 50769 Koeln Germany	Germany	Active	2-methylprop-1-ene, pentamer	610-010-2	42278-27-3	2020; 2022	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2,7-dihydroxyfluoren-9-one	610-035-9	42523-29-5	2018	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	6-Bromo-1-hexanol	610-072-0	4286-55-9	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	1-Naphthalenemethanamine, a-methyl-	610-076-2	42882-31-5	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
Výzkumný ústav organických syntéz a.s.	č.p. 296 533 54 Rybitví Czech Republic	Czech Republic	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
BLENDWELL SA	rue Benoît, 50 Zoning Industriel B-7370 Dour Belgium	Belgium	Active	Benzenesulfonic acid, 2-amino-5-((2-(sulfooxy)ethyl)sulfonyl)-	610-097-7	42986-22-1	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	5’,5’’’’-(1,1,1-trifluoropropane-2,2-diyl)bis(1,1’:3’,1’’-terphenyl-2’-ol)	610-104-3	43100-47-6	-	View substance registered dossier
EUROAPI Hungary Ltd.	Tó utca 1-5. 1045 Budapest Hungary	Hungary	Active	(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	-	View substance registered dossier
SONEAS Chemicals Ltd.	Banyaleg Str. 47-59. H-1225 Budapest Hungary	Hungary	Active	(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one	610-106-4	43119-28-4	2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione	610-113-2	4318-56-3	-	View substance registered dossier
JSC Grindeks	53 Krustpils St LV 1057 Riga Latvia	Latvia	Active	6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate	610-114-8	43200-88-0	2017; 2019	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	2-[benzyl-[1-(4-methoxyphenyl)propan-2-yl]amino]-1-(3-nitro-4-phenylmethoxyphenyl)ethanone	610-116-9	43229-66-9	2018; 2019	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	[(2S,3R,5S)-3-acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate	610-122-1	433733-94-9	2021	View substance registered dossier
Thermal Ceramics de France S.A.S.	3, Rue du 18 Juin 1827 42160 Andrezieux-Boutheon France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2014; 2015; 2016; 2019; 2020; 2021	View substance registered dossier
WSP Deutschland A.G. (OR12)	Dingolfinger Straße 1-15 81673 Munchen Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
KCC Europe GmbH	Hansaring 61 50670 Köln Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Nutec Europe, S.L.	Eitua Industrialdea 71 A 48240 Berriz Spain	Spain	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Thermal Ceramics de France S.A.S.	3 rue du 18 Juin 1827 42160 Andrezieux-Boutheon France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Meca-Trade OY	Mikkolantie 32 FIN-28130 Pori Finland	Finland	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
IIP Europe GmbH	Fritz-Vomfelde-Str.34 40547 Duesseldorf Germany	Germany	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	-	View substance registered dossier
Vulcor Insulation BV(Hubei SOLI New Materials Technology Co. , Ltd)	Wanraaij 4 6673 DN Andelst Netherlands	Netherlands	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2023	View substance registered dossier
Thermal Ceramics UK Ltd	Tebay Road CH62 3PH Bromborough Wirral United Kingdom	United Kingdom	No longer Valid	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2021	View substance registered dossier
Unifrax France	Mill Lane, Rainford Lorette Wa118LP St Helens, merseyside, France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2010; 2021	View substance registered dossier
Unifrax France 001	17 Rue Antoine Durafour Lorette 42420 Lorette France	France	Active	amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide	610-130-5	436083-99-7	2010	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl) benzenesulfonic acid	610-141-5	437717-43-6	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	2,6-Difluorobenzaldehyde	610-142-0	437-81-0	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	triphenyl(((1r,4r)-4-((E)-prop-1-en-1-yl)cyclohexyl)methyl)phosphonium iodide	610-150-4	438193-30-7	2018	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethane-1-sulfonyl chloride	610-161-4	4403-36-5	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	9H-fluorene-9,9-diyldimethanol	610-170-3	4425-93-8	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	7-[2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)acetamido]-3-vinyl-cephem-4-carboxylic acid	610-178-7	443874-49-5	2021	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	2,3-dimethyl-2H-indazol-6-amine	610-188-1	444731-72-0	2021	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018; 2022	View substance registered dossier
Medichem S.A.	Polígon Industrial de Celrà 17460 Celrà Girona Spain	Spain	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	2012; 2018; 2020; 2022	View substance registered dossier
Medichem Manufacturing (Malta) Limited	HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta	Malta	Active	2-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione	610-201-0	446292-08-6	-	View substance registered dossier
[Confidential]	-	-	-	N-(5-bromo-3-methylpyridin-2-yl)-N-methylbenzamide	610-202-6	446299-80-5	-	View substance registered dossier
[Confidential]	-	-	-	Boronic acid, [6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-	610-203-1	446299-81-6	-	View substance registered dossier
[Confidential]	-	-	-	3-Quinolinecarboxylic acid, 7-[6-(benzoylmethylamino)-5-methyl-3-pyridinyl]-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester	610-204-7	446299-90-7	-	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	N6-Benzoyladenosine	610-251-3	4546-55-8	2022	View substance registered dossier
Biosynth s.r.o.	Nobelova 34 83605 Bratislava Slovakia	Slovakia	Active	N6-Benzoyladenosine	610-251-3	4546-55-8	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione	610-252-9	4547-02-8	2018	View substance registered dossier
Alzchem Trostberg GmbH	Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany	Germany	Active	6,8-disulfanyloctanoic acid	610-288-5	462-20-4	2021	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	2-Amino-4,5-dimethyl-thiophene-3-carbonitrile	610-309-8	4651-94-9	2012	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Active	(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(2S)-2-(2-AMINO-5-CHLOROPHENYL)-4-CYCLOPROPYL-1,1, 1-TRIFLUOROBUT-3-YN-2-OL METHANESULFONATE (1:1.5)	610-316-6	467426-34-2	2017	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	2,3-Difluor-1-propoxy-4-[trans-4-(trans-4-propylcyclohexyl)- cyclohexyl]-benzene	610-336-5	473257-14-6	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-[trans-4-(trans-4-butylcyclohexyl)-cyclohexyl]-1-ethoxy-2, 3-difluorobenzene	610-337-0	473257-15-7	-	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Active	1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	1-(1,3-dioxolan-2-ylidene)-1H-indene-3-carbonitrile	610-344-9	474024-38-9	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	Sodium 3-hydroxy-5-sulfanyl-1,2-thiazole-4-carboxylate	610-355-9	475112-25-5	-	View substance registered dossier
IFF Benicarlo, S.L.	Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain	Spain	Active	1,1,2,3,3-pentamethyl-5-(2-methylprop-2-en-1-yl)octahydro-4H-inden-4-one	610-371-6	476332-63-5	2021	View substance registered dossier
WeylChem Lamotte S.A.S	Rue du Flottage B.P. 1 60350 Trosly Breuil France	France	Active	Iron(1+), chloro[dimethyl 9,9-dihydroxy-3-methyl-2,4-di(2-pyridinyl-kN)-7-[(2-pyridinyl-kN)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate-kN3,kN7]-, chloride	610-388-9	478945-46-9	2018; 2021	View substance registered dossier
Fujifilm Imaging Colorants Limited	Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom	United Kingdom	No longer Valid	3-(3,4-dicyanophenylsulfonyl)propane-1-sulfonyl chloride	610-401-8	480427-96-1	2021	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	2020	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl	610-428-5	486406-09-1	2022	View substance registered dossier
Isobionics B.V.	Urmonderbaan 22 6167 RD Geleen Netherlands	Netherlands	Active	(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	3-(3,4-Dimethoxyphenyl)propanenitrile	610-465-7	49621-56-9	-	View substance registered dossier
Wychem Limited	Bury Road CB8 8YN Stradishall Suffolk United Kingdom	United Kingdom	No longer Valid	2-Bromo-4-fluorophenol	610-467-8	496-69-5	2021	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2,2-dioxo-1,2λ6-benzoxathiin-4-one	610-468-3	49670-47-5	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene] hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid	610-469-9	496775-61-2	2021	View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH	Riedstrasse 2 89555 Steinheim Germany	Germany	Active	N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	-	View substance registered dossier
CIBA VISION GmbH	Industriering1 63868 Großwallstadt Bavaria Germany	Germany	Active	N-(2,2-dimethoxyethyl)prop-2-enamide	610-472-5	49707-23-5	2021	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	methyl 2,6,6-trimethyl-1-cyclohexene-1-carboxylate	610-481-4	49815-58-9	2021	View substance registered dossier
[Confidential]	-	-	-	2-(3-Chloro-2-pyridinyl)-5-oxo-3-pyrazolidinecarboxylic acid ethyl ester	610-490-3	500011-88-1	-	View substance registered dossier
[Confidential]	-	-	-	Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate	610-491-9	500011-92-7	-	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	-	View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company	Little Island County NA Cork Ireland	Ireland	Active	(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE	610-496-6	500292-86-4	-	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Cease Manufacture	L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester	610-513-7	502421-44-5	2022	View substance registered dossier
Corden Pharma Bergamo S.p.A.	Via Bergamo, 121 IT-24047 Treviglio BG Italy	Italy	Active	2-Propanol, 1-(3,5-dimethylphenoxy)-3-[(phenylmethyl)amino]-	610-515-8	502605-82-5	-	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt	610-522-6	503155-49-5	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	2020	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Cease Manufacture	(5α)-Androsta-2,16-dien-17-yl acetate	610-545-1	50588-42-6	2019	View substance registered dossier
CSI-OR47DUB	Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland	Ireland	Cease Manufacture	2-Hydroxy-4-(trifluoromethyl)pyridine	610-554-0	50650-59-4	2023	View substance registered dossier
Clariant Produkte (Deutschland) GmbH	August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany	Germany	Active	4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	-	View substance registered dossier
[Confidential]	-	-	-	4-methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one	610-555-6	50650-75-4	-	View substance registered dossier
Aspen Oss BV	Kloosterstraat 6 5349 AB Oss Netherlands	Netherlands	Active	[(8R,9S,10R,13S,14S,17R)-3-ethoxy-17-ethynyl-13-methyl-2,7,8,9,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate	610-565-0	50717-99-2	2018	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	(R)-2-acetoxy-2-phenylacetic acid	610-598-0	51019-43-3	-	View substance registered dossier
Galata Chemicals GmbH	Chemiestrasse 22 68623 Lampertheim 06 Germany	Germany	Active	2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-7-oxo-8-oxa-3,5-dithia-4-phosphatetradecanoate 4-oxide	610-601-5	51032-53-2	2018	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	1,2,4,9-Tetrahydrocarbazol-3-one	610-619-3	51145-61-0	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	5-Brom-2-[(3,4,5-trifluorphenoxy)-difluormethyl]-1,3-difluorbenzene	610-623-5	511540-64-0	2018; 2021	View substance registered dossier
KLK Kolb Specialties B.V.	Langestraat 167 7491AE Delden Overijssel Netherlands	Netherlands	Active	oils, palm, propoxylated	610-641-3	512802-65-2	2019	View substance registered dossier
FARMAK, a.s.	Na vlcinci 16/3 779 00 Olomouc Czech Republic	Czech Republic	Active	5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine	610-648-1	51322-75-9	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	2-Chloro-1-(3,4-difluorophenyl)ethanone	610-651-8	51336-95-9	2009	View substance registered dossier
SPAA s.r.l.	Via delle Industrie, 11-13 65013 Città Sant'Angelo PE Italy	Italy	Active	Phosphonic acid, diammonium salt, monohydrate	610-672-2	51503-61-8	-	View substance registered dossier
Kerona Scientific Limited	14 Thomas Hand Street K34 A375 Skerries Dublin Ireland	Ireland	Active	Phosphonic acid, diammonium salt, monohydrate	610-672-2	51503-61-8	-	View substance registered dossier
FINORGA SAS	497 route de Givors 38670 CHASSE SUR RHONE France	France	Active	2-Propenoic acid, 3-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, methyl ester, hydrochloride (1:1)	610-682-7	51531-46-5	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(2E)-3-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methylprop-2-enal	610-698-4	51575-61-2	-	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	2019	View substance registered dossier
SAFIC ALCAN	13 Cours Valmy 92977 Paris La Défense France	France	Active	(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione	610-717-6	5173-46-6	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	Rifamycin, 3-amino-1,4-dideoxy-1,4-dihydro-1,4-dioxo-(9Cl)	610-723-9	51756-80-0	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	Diphenylmethyl (6R)-3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate	610-726-5	51762-51-7	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	{4-[2-(Dimethylamino)ethoxy]phenyl}(phenyl)methanone	610-729-1	51777-15-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	1-amino-2-(1-methyl-1-phenoxycarbonylamino-ethyl)-oxime	610-731-2	518047-98-8	2017	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	5-hydroxy-1-methyl-2-(1-methyl-1-phenoxycabonylamino-ethyl)-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid 4-fluorobenzylamide	610-732-8	518048-02-7	-	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide	610-733-3	518048-05-0	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	5,8-Dihydro-1-naphthyl acetate	610-759-5	51927-56-1	-	View substance registered dossier
INKE, S.A.	Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain	Spain	Active	4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	-	View substance registered dossier
POLPHARMA	19 Pelplińska 83-200 Starogard Gdański Poland	Poland	Active	4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	2017	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	4-(oxiran-2-ylmethoxy)-9H-carbazole	610-764-2	51997-51-4	2017	View substance registered dossier
Saes Getters S.p.A.	Viale Italia 77 20020 Lainate (MI) Italy	Italy	Active	Nickel, compound with Titanium (1:1)	610-765-8	52013-44-2	-	View substance registered dossier
Výzkumný ústav organických syntéz a.s.	č.p. 296 533 54 Rybitví Czech Republic	Czech Republic	Active	2-(2-ethoxyphenoxy)ethanamine methanesulfonate	610-786-2	521300-98-1	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	Potassium [(4-{2-[(5-chloro-2-methoxybenzoyl)amino]ethyl}phenyl)sulfonyl](cyclohexylamino)carbonyl]azanide	610-790-4	52169-36-5	-	View substance registered dossier
LusoChimica S.p.A.	Via Giotto, 9 23871 Lomagna (Lecco) Italy	Italy	Active	Potassium [(4-{2-[(5-chloro-2-methoxybenzoyl)amino]ethyl}phenyl)sulfonyl](cyclohexylamino)carbonyl]azanide	610-790-4	52169-36-5	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	Potassium [(4-{2-[(5-chloro-2-methoxybenzoyl)amino]ethyl}phenyl)sulfonyl](cyclohexylamino)carbonyl]azanide	610-790-4	52169-36-5	-	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	4-(4-chlorophenyl)-3-methyl-4-oxo-butanoic acid	610-810-1	52240-25-2	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	Ethyl-(3-hydroxypropyl)propanedioic acid	610-813-8	52250-47-2	2020	View substance registered dossier
THOR GmbH	Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany	Germany	Active	N-Methyl-3-sulfanylpropanamide	610-826-9	52334-99-3	-	View substance registered dossier
WeylChem Griesheim GmbH	Stroofstr. 27 D-65933 Frankfurt am Main Germany	Germany	Cease Manufacture	4-Cyano-2nitrobenzoic acid methyl ester	610-840-5	52449-76-0	2019	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-Cyano-2nitrobenzoic acid methyl ester	610-840-5	52449-76-0	2013	View substance registered dossier
JSC "Olainfarm"	Rupnicu str. 5 LV-2114 Olaine Latvia	Latvia	Active	ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate	610-841-0	52450-32-5	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	2',3,5-Trifluoro-4''-(trans-4-propylcyclohexyl)-4-trifluoromethoxy-[1,1';4',1'']terphenyl	610-847-3	524709-77-1	-	View substance registered dossier
Sachem Europe BV	Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands	Netherlands	Active	dimethyl(dipropyl)azanium;bromide	610-854-1	52509-52-1	-	View substance registered dossier
[Confidential]	-	-	-	5-amino-3-methyl-2,4-thiophenedicarbonitrile	610-868-8	52603-48-2	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	Oxirane, 2-methyl-, oligomeric reaction products with oxirane, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1)	610-877-7	52624-57-4	-	View substance registered dossier
WeylChem Lamotte S.A.S	Rue du Flottage B.P. 1 60350 Trosly Breuil France	France	Active	1H-1,4,7-Triazonine, octahydro-1,4,7-tris[(4-methylphenyl)sulfonyl]-	610-880-3	52667-89-7	2021	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Weifang Binhai Petro-chem. Co., Ltd)	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	octan-2-yl cyanoacetate	610-886-6	52688-08-1	2012; 2013; 2016	View substance registered dossier
Henkel Ireland Operations and Research Ltd. - Non Phase In Substances	Tallaght Business Park, Whitestown, Tallaght 24 Dublin Ireland	Ireland	Cease Manufacture	octan-2-yl cyanoacetate	610-886-6	52688-08-1	2011	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	isobutyl (2Z)-3-aminobut-2-enoate	610-915-2	52937-90-3	2021	View substance registered dossier

Showing 20,001 - 20,100 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.