Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2R-(2α,3Z,5α))-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 1:1 salt with 2,4,4-Trimethylpentan-2-amine
613-879-6 66069-32-7 Active Intermediate Individual Intermediate use only 20-05-2013 View substance registered dossier
(2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[( 1H-1,2,4-triazol-1-yl)methyl]oxirane 406-850-2 133855-98-8 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol
682-862-3 78715-23-8 No longer Valid Intermediate Individual No longer valid 11-01-2016 View substance registered dossier
(2S)-1,1-diphenylpropane-1,2-diol
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(2S)-1-(2-aminoacetyl)-N-[(1S)-1-(tert-butoxymethyl)-2-oxo-2-[[(1S)-1-(tert-butoxymethyl)-2-oxo-2-[[2-oxo-2-[[(1S)-1-methyl-2-oxo-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]ethyl]amino]ethyl]amino]ethyl]amino]ethyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid
955-960-1 2656383-23-0 Active Intermediate Individual Intermediate use only 16-09-2022 View substance registered dossier
(2S)-1-tert-butoxycarbonyl-2,3-dihydropyrrole-2-carboxylic acid;N-cyclohexylcyclohexanamine
618-453-3 90104-21-5 Active Intermediate Individual Intermediate use only 21-03-2017 View substance registered dossier
(2S)-2-(17-carbonitrile-3,6-dimethoxy-4,5α-epoxy-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol
605-429-2 16614-60-1 No longer Valid Intermediate Individual No longer valid 11-01-2016 View substance registered dossier
(2S)-2-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol
605-274-0 16196-70-6 No longer Valid Intermediate Individual No longer valid 08-01-2016 View substance registered dossier
(2S)-2-(benzyloxy)propanal
617-235-5 81445-44-5 Active Intermediate Individual Intermediate use only 08-10-2018 View substance registered dossier
(2S)-2-(chloromethyl)oxirane
482-080-0 67843-74-7 Active Full Individual ≥ 10 to < 100 tonnes 11-04-2011 View substance registered dossier
(2S)-2-[2-[[(1S)-1,2-dicarboxyethyl]amino]ethylamino]butanedioic acid
439-840-1 161233-89-2 Active Full Individual ≥ 100 to < 1 000 tonnes 11-01-2013 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid
954-943-6 - Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
(2S)-2-amino-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoic acid
619-013-3 94345-95-6 Active Full Individual ≥ 1 to < 10 tonnes 10-09-2021 View substance registered dossier
(2S)-2-Aminobutyramide Hydrochloride
471-490-5 7682-20-4 Cease Manufacture NONS Individual Cease manufacture 15-12-2008 View substance registered dossier
(2S)-2-benzyl-N,N-dimethylaziridine-1-sulfonamide
620-285-0 902146-43-4 Active Intermediate Individual Intermediate use only 05-06-2012 View substance registered dossier
(2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone
601-833-8 122151-38-6 Active Intermediate Individual Intermediate use only 24-01-2018 View substance registered dossier
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile
441-070-6 61826-76-4 No longer Valid NONS Individual No longer valid 04-06-2012 View substance registered dossier
(2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid
430-900-2 192725-50-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
604-045-2 137862-53-4 Active Intermediate Individual Intermediate use only 07-08-2014 View substance registered dossier
(2S)-4-amino-2-hydroxy-butanoic acid
670-305-7 40371-51-5 Active Intermediate Individual Intermediate use only 27-01-2020 View substance registered dossier
(2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid
810-842-8 129101-36-6 Active Intermediate Individual Intermediate use only 08-03-2016 View substance registered dossier
(2S)-but-3-yn-2-yl methanesulfonate
857-677-8 73647-37-7 Active Intermediate Individual Intermediate use only 24-07-2020 View substance registered dossier
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
617-525-1 84057-95-4 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
(2S)-propane-1,2-diamine dihydrochloride
606-377-3 19777-66-3 Active Intermediate Individual Intermediate use only 16-09-2015 View substance registered dossier
(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid
478-210-0 69901-75-3 Cease Manufacture Intermediate Individual Cease manufacture 05-11-2012 View substance registered dossier
(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid
478-210-0 69901-75-3 No longer Valid Intermediate Individual No longer valid 19-10-2012 View substance registered dossier
(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid
478-210-0 69901-75-3 No longer Valid Intermediate Individual No longer valid 19-10-2012 View substance registered dossier
(2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran
941-817-0 - Active Intermediate Individual Intermediate use only 10-02-2015 View substance registered dossier
(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid
800-213-6 1007881-21-1 Active Intermediate Individual Intermediate use only 07-11-2018 View substance registered dossier
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran
835-228-7 211801-54-6 Cease Manufacture Intermediate Individual Cease manufacture 05-03-2019 View substance registered dossier
(2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate
921-285-6 1071929-02-6 Cease Manufacture Intermediate Individual Cease manufacture 29-09-2015 View substance registered dossier
(2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate
921-285-6 1071929-02-6 Active Intermediate Individual Intermediate use only 05-01-2016 View substance registered dossier
(2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid
606-247-6 191605-10-4 Cease Manufacture Intermediate Individual Cease manufacture 12-12-2008 View substance registered dossier
(2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2)
954-871-5 - Active Intermediate Individual Intermediate use only 19-08-2021 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - No longer Valid Intermediate Individual No longer valid 19-10-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Individual Cease manufacture 05-11-2012 View substance registered dossier
(2S,3S,3aR,9aS)-3-hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tertryhydro-6H-furo[2’,3’:4,5][1,3]oxazolo [3,2-a]pyrimidin-6-one
700-330-1 433733-92-7 Active Full Individual ≥ 0 to < 10 tonnes 16-04-2019 View substance registered dossier
(2S,3S,4R)-2-aminooctadecane-1,3,4-triol
439-210-6 554-62-1 Active NONS Individual Tonnage data confidential 02-09-2011 View substance registered dossier
(2S,4S) 4-Hydroxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-butyl ester 2-methyl ester
807-618-7 1194059-42-1 Active Intermediate Individual Intermediate use only 20-04-2016 View substance registered dossier
(2S,4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid
812-482-7 1643468-66-9 Active Intermediate Individual Intermediate use only 17-05-2016 View substance registered dossier
(2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxamide
812-263-6 1416134-49-0 Active Intermediate Individual Intermediate use only 10-05-2016 View substance registered dossier
(2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
812-287-7 1192651-49-2 Active Intermediate Individual Intermediate use only 17-05-2016 View substance registered dossier
(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetic acid
616-178-3 75028-24-9 No longer Valid Intermediate Individual No longer valid 24-06-2013 View substance registered dossier
(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetic acid
616-285-5 76028-96-1 Active Intermediate Individual Intermediate use only 26-04-2013 View substance registered dossier
(2Z)-2-chloro-3-(dimethylamino)-N,N-dimethylprop-2-en-1-iminium hexafluorophosphate
619-785-1 249561-98-6 Active Intermediate Individual Intermediate use only 23-05-2011 View substance registered dossier
(2Z)-2-phenylhex-2-enenitrile
482-160-5 130786-09-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2Z)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one
616-378-0 767340-03-4 Active Intermediate Individual Intermediate use only 08-10-2012 View substance registered dossier
(2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
601-596-0 119302-24-8 Active Full Individual ≥ 1 to < 10 tonnes 20-02-2014 View substance registered dossier
(3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one
17-KETOBROMOHYDRINE
419-790-7 4229-69-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(3,4,5-Trifluorophenyl)boronic Acid (contains varying amounts of Anhydride)
604-355-8 143418-49-9 Active Intermediate Individual Intermediate use only 11-10-2010 View substance registered dossier
(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine
917-818-7 73344-75-9 Cease Manufacture Intermediate Individual Cease manufacture 19-01-2012 View substance registered dossier
(3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane)
LC-OLIGOMER
454-660-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3-(C20-24-(even numbered)-alkyl-2-enyl)-dihydro-furan-2,5-dion
615-230-2 70983-53-8 Active Intermediate Individual Intermediate use only 11-05-2017 View substance registered dossier
(3-aminophenyl)pyridin-3-ylmethanone
428-230-0 79568-06-2 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(3-chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanone
689-199-9 680610-70-2 Active Intermediate Individual Intermediate use only 10-11-2016 View substance registered dossier
(3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride
221-083-1 3001-63-6 Active Intermediate Individual Intermediate use only 22-07-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Individual Intermediate use only 08-01-2014 View substance registered dossier
(3-chloro-4-methoxyphenyl)methanaminium chloride
609-972-6 41965-95-1 Active Intermediate Individual Intermediate use only 21-01-2014 View substance registered dossier
(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
T 1569; T001569
423-290-4 66938-41-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate
700-367-3 35130-97-3 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3-Methyl-but-2-enyloxy)-benzol
846-080-8 14309-15-0 Active Intermediate Individual Intermediate use only 01-07-2020 View substance registered dossier
(3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride Tetrahydrofuran Adduct
480-140-0 250220-36-1 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate
700-396-1 60924-38-1 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE
443-930-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
931-336-4 - Cease Manufacture Intermediate Individual Cease manufacture 13-09-2012 View substance registered dossier
(3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid
617-116-8 80573-04-2 Active Full Individual ≥ 1 to < 10 tonnes 17-05-2019 View substance registered dossier
(3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one
948-498-7 143785-33-5 Active Full Individual ≥ 1 to < 10 tonnes 12-10-2022 View substance registered dossier
(3R)-3-aminobutan-1-ol-(2S)-2-hydroxy-2-phenyl-acetate
810-156-9 1236049-43-6 Active Intermediate Individual Intermediate use only 15-02-2016 View substance registered dossier
(3R)-3-methylpiperazin-2-one
693-438-2 922178-61-8 Active Intermediate Individual Intermediate use only 30-05-2021 View substance registered dossier
(3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
954-618-9 - Active Intermediate Individual Intermediate use only 21-03-2022 View substance registered dossier
(3R,3aR,6R,6aR)-6-[(4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl 4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoate
700-376-2 1015689-48-1 Active Full Individual ≥ 0 to < 10 tonnes 16-02-2010 View substance registered dossier
(3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diyl dioctanoate
807-840-4 64896-70-4 Active Full Individual ≥ 10 to < 100 tonnes 13-03-2015 View substance registered dossier
(3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime
603-883-6 134931-01-4 Cease Manufacture Intermediate Individual Cease manufacture 25-10-2012 View substance registered dossier
(3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on
608-732-8 32384-65-9 Active Intermediate Individual Intermediate use only 19-01-2015 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
603-467-4 13127-18-9 Cease Manufacture Intermediate Individual Cease manufacture 22-10-2010 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride
607-864-3 26116-57-4 Active Intermediate Individual Intermediate use only 26-05-2014 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride
607-864-3 26116-57-4 Active Intermediate Individual Intermediate use only 02-05-2013 View substance registered dossier
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one
700-290-5 63968-64-9 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde
812-036-1 1214741-19-1 Cease Manufacture Intermediate Individual Cease manufacture 28-04-2016 View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
942-823-6 - Cease Manufacture Intermediate Individual Cease manufacture 03-11-2015 View substance registered dossier
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione
810-392-2 171284-84-7 Cease Manufacture Intermediate Individual Cease manufacture 07-09-2015 View substance registered dossier
(3S)-3-hydroxypyrrolidin-2-one
676-349-3 34368-52-0 Active Intermediate Individual Intermediate use only 12-11-2019 View substance registered dossier
(3S)-9,10-difluoro-2,3-dihidro-3-metil-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxacine-6-carboxílic acid ethyl ester
691-244-2 106939-34-8 Active Intermediate Individual Intermediate use only 12-06-2014 View substance registered dossier
(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate
603-567-8 132335-47-8 Active Intermediate Individual Intermediate use only 08-10-2009 View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide
PTH-AA
430-230-0 136522-17-3 Cease Manufacture NONS Individual Cease manufacture 13-09-2010 View substance registered dossier
(3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Cease Manufacture Intermediate Individual Cease manufacture 29-10-2012 View substance registered dossier
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile
634-598-5 106565-71-3 Cease Manufacture Intermediate Individual Cease manufacture 15-10-2014 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
610-965-5 53123-88-9 Cease Manufacture Intermediate Individual Cease manufacture 26-08-2014 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 Cease Manufacture Full Individual Cease manufacture 17-08-2015 View substance registered dossier
(3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether
439-790-0 292605-05-1 Active Full Individual ≥ 0 to < 10 tonnes 18-01-2013 View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one
427-070-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-Chloro-2-fluoro-phenyl)-acetonitrile
642-783-7 75279-53-7 Cease Manufacture Intermediate Individual Cease manufacture 30-03-2016 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 No longer Valid Intermediate Individual No longer valid 13-11-2013 View substance registered dossier
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
SULPHAZINE
406-090-1 81880-96-8 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(4-methylphenyl)mesitylene sulfonate
KAYAKU TG-MC
407-530-5 67811-06-7 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
SUANFARMA Italia SpA Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy Italy Active (2R-(2α,3Z,5α))-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 1:1 salt with 2,4,4-Trimethylpentan-2-amine 613-879-6 66069-32-7 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[( 1H-1,2,4-triazol-1-yl)methyl]oxirane 406-850-2 133855-98-8 2021 View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom United Kingdom No longer Valid (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol 682-862-3 78715-23-8 2021 View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (2S)-1,1-diphenylpropane-1,2-diol 443-220-6 46755-94-6 2019 View substance registered dossier
[Confidential] - - - (2S)-1-(2-aminoacetyl)-N-[(1S)-1-(tert-butoxymethyl)-2-oxo-2-[[(1S)-1-(tert-butoxymethyl)-2-oxo-2-[[2-oxo-2-[[(1S)-1-methyl-2-oxo-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]ethyl]amino]ethyl]amino]ethyl]amino]ethyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid 955-960-1 2656383-23-0 - View substance registered dossier
[Confidential] - - - (2S)-1-tert-butoxycarbonyl-2,3-dihydropyrrole-2-carboxylic acid;N-cyclohexylcyclohexanamine 618-453-3 90104-21-5 - View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom United Kingdom No longer Valid (2S)-2-(17-carbonitrile-3,6-dimethoxy-4,5α-epoxy-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol 605-429-2 16614-60-1 2021 View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom United Kingdom No longer Valid (2S)-2-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol 605-274-0 16196-70-6 2021 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-(benzyloxy)propanal 617-235-5 81445-44-5 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (2S)-2-(chloromethyl)oxirane 482-080-0 67843-74-7 2011 View substance registered dossier
Innospec Performance Chemicals France SAS (Only Rep 2) Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France France Active (2S)-2-[2-[[(1S)-1,2-dicarboxyethyl]amino]ethylamino]butanedioic acid 439-840-1 161233-89-2 2012; 2013 View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2012 View substance registered dossier
[Confidential] - - - (2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid 954-943-6 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Active (2S)-2-amino-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoic acid 619-013-3 94345-95-6 2021 View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duesseldorf Germany Germany Cease Manufacture (2S)-2-Aminobutyramide Hydrochloride 471-490-5 7682-20-4 2013 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2S)-2-benzyl-N,N-dimethylaziridine-1-sulfonamide 620-285-0 902146-43-4 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone 601-833-8 122151-38-6 - View substance registered dossier
DOW CHEMICAL COMPANY LTD Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom United Kingdom No longer Valid (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile 441-070-6 61826-76-4 2021 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid 430-900-2 192725-50-1 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy IE Ringaskiddy Cork Ireland Ireland Active (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid 604-045-2 137862-53-4 2014 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (2S)-4-amino-2-hydroxy-butanoic acid 670-305-7 40371-51-5 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid 810-842-8 129101-36-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2S)-but-3-yn-2-yl methanesulfonate 857-677-8 73647-37-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide 617-525-1 84057-95-4 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (2S)-propane-1,2-diamine dihydrochloride 606-377-3 19777-66-3 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid 478-210-0 69901-75-3 2019 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid 478-210-0 69901-75-3 2021 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid 478-210-0 69901-75-3 2021 View substance registered dossier
[Confidential] - - - (2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran 941-817-0 - - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid 800-213-6 1007881-21-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran 835-228-7 211801-54-6 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate 921-285-6 1071929-02-6 2019 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate 921-285-6 1071929-02-6 - View substance registered dossier
Warsaw University of Technology, Faculty of Chemistry, Laboratory of Technological Processes Noakowskiego 3 00-664 Warszawa Poland Poland Cease Manufacture (2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid 606-247-6 191605-10-4 2014 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2) 954-871-5 - - View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (2S,3S,3aR,9aS)-3-hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tertryhydro-6H-furo[2’,3’:4,5][1,3]oxazolo [3,2-a]pyrimidin-6-one 700-330-1 433733-92-7 2008; 2010; 2019 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (2S,3S,4R)-2-aminooctadecane-1,3,4-triol 439-210-6 554-62-1 2011 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S,4S) 4-Hydroxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-butyl ester 2-methyl ester 807-618-7 1194059-42-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S,4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid 812-482-7 1643468-66-9 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxamide 812-263-6 1416134-49-0 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide 812-287-7 1192651-49-2 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid (2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetic acid 616-178-3 75028-24-9 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetic acid 616-285-5 76028-96-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2Z)-2-chloro-3-(dimethylamino)-N,N-dimethylprop-2-en-1-iminium hexafluorophosphate 619-785-1 249561-98-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2Z)-2-phenylhex-2-enenitrile 482-160-5 130786-09-3 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2Z)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one 616-378-0 767340-03-4 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane 601-596-0 119302-24-8 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one 419-790-7 4229-69-0 2019 View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active (3,4,5-Trifluorophenyl)boronic Acid (contains varying amounts of Anhydride) 604-355-8 143418-49-9 2008; 2010 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture (3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine 917-818-7 73344-75-9 2013 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane) 454-660-3 - - View substance registered dossier
Clariant Ibérica Producción S.A. Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain Spain Active (3-(C20-24-(even numbered)-alkyl-2-enyl)-dihydro-furan-2,5-dion 615-230-2 70983-53-8 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture (3-aminophenyl)pyridin-3-ylmethanone 428-230-0 79568-06-2 2015 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3-chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanone 689-199-9 680610-70-2 - View substance registered dossier
Ricardo Nederland BV Daalsesingel 51 3511 SW Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride 221-083-1 3001-63-6 2021 View substance registered dossier
Clariant Produkte (Deutschland) GmbH August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active (3-chloro-4-methoxyphenyl)methanaminium chloride 609-972-6 41965-95-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone 423-290-4 66938-41-8 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate 700-367-3 35130-97-3 2012 View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active (3-Methyl-but-2-enyloxy)-benzol 846-080-8 14309-15-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride Tetrahydrofuran Adduct 480-140-0 250220-36-1 2022 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate 700-396-1 60924-38-1 2012 View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE 443-930-6 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) 931-336-4 - 2019 View substance registered dossier
PharmaZell GmbH Rosenheimer Straße 43 D-83064 Raubling Germany Germany Active (3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid 617-116-8 80573-04-2 2019 View substance registered dossier
PFW Aroma Ingredients B.V. Veemweg 29-31 3771 MT Barneveld Gelderland Netherlands Netherlands Active (3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one 948-498-7 143785-33-5 2019; 2022 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (3R)-3-aminobutan-1-ol-(2S)-2-hydroxy-2-phenyl-acetate 810-156-9 1236049-43-6 2016 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-3-methylpiperazin-2-one 693-438-2 922178-61-8 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one 954-618-9 - 2022 View substance registered dossier
SICPA Germany GmbH Gewerbepark Lindach D7 84489 Burghausen Germany Germany Active (3R,3aR,6R,6aR)-6-[(4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl 4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoate 700-376-2 1015689-48-1 - View substance registered dossier
OLEON N.V. Industriezone "ter straten" Vaartstraat 220 2520 Oelegem Belgium Belgium Active (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diyl dioctanoate 807-840-4 64896-70-4 2015 View substance registered dossier
[Confidential] - - - (3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime 603-883-6 134931-01-4 - View substance registered dossier
[Confidential] - - - (3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on 608-732-8 32384-65-9 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Cease Manufacture (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 603-467-4 13127-18-9 2017 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride 607-864-3 26116-57-4 - View substance registered dossier
Sandoz Industrial Products SA Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Catalunya Spain Spain Active (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride 607-864-3 26116-57-4 - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one 700-290-5 63968-64-9 2009; 2010; 2012 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde 812-036-1 1214741-19-1 2019 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 942-823-6 - 2019 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione 810-392-2 171284-84-7 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (3S)-3-hydroxypyrrolidin-2-one 676-349-3 34368-52-0 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (3S)-9,10-difluoro-2,3-dihidro-3-metil-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxacine-6-carboxílic acid ethyl ester 691-244-2 106939-34-8 2014 View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active (3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate 603-567-8 132335-47-8 2009 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide 430-230-0 136522-17-3 2020 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 2020 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Germany Germany Cease Manufacture (3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile 634-598-5 106565-71-3 2020 View substance registered dossier
- - - - (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Cease Manufacture (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone 610-965-5 53123-88-9 2017 View substance registered dossier
Santrol Europe ApS Aagade 103 Pjedsted 7000 Fredericia Denmark Denmark Cease Manufacture (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 2016 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether 439-790-0 292605-05-1 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one 427-070-9 - - View substance registered dossier
Derivados Quimicos SAU Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain Spain Cease Manufacture (4-Chloro-2-fluoro-phenyl)-acetonitrile 642-783-7 75279-53-7 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2010 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2018 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride 406-090-1 81880-96-8 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (4-methylphenyl)mesitylene sulfonate 407-530-5 67811-06-7 2022 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.