Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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First published date:
Last update date:
Substance data
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Uses and exposure
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  • Consumer Uses
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Details
1,3-dichloro-5-ethyl-5-methylimidazolidine-2,4-dione
401-570-7 89415-87-2 No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
1,3-dichlorobenzene 208-792-1 541-73-1 Active Intermediate Individual Intermediate use only 07-10-2015 View substance registered dossier
1,3-dichlorobut-2-ene
213-138-3 926-57-8 Active Intermediate Individual Intermediate use only 02-11-2010 View substance registered dossier
1,3-dichloropropan-2-ol
202-491-9 96-23-1 Active Intermediate Individual Intermediate use only 29-09-2015 View substance registered dossier
1,3-dichloropropane
205-531-3 142-28-9 Active Full Individual Tonnage data confidential 31-05-2018 View substance registered dossier
1,3-dihydro-1,3-dioxo-2H-isoindole-2-hexanoic acid
224-675-8 4443-26-9 Active Intermediate Individual Intermediate use only 05-07-2012 View substance registered dossier
1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione
253-326-2 37052-78-1 Active Intermediate Individual Intermediate use only 20-09-2013 View substance registered dossier
1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione
253-326-2 37052-78-1 Active Intermediate Individual Intermediate use only 06-05-2013 View substance registered dossier
1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate
605-637-3 172529-93-0 No longer Valid Intermediate Individual No longer valid 13-03-2012 View substance registered dossier
1,3-Dioxan-2-one
423-980-5 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- - 117933-89-8 Active Full Individual ≥ 1 to < 10 tonnes 14-02-2019 View substance registered dossier
1,3-dioxane, 2-(3,3-dimethyl-1-cyclohexen-1-yl)-2,5,5-trimethyl
815-500-1 1853175-99-1 Active Full Individual ≥ 1 to < 10 tonnes 18-07-2018 View substance registered dossier
1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 29-09-2010 View substance registered dossier
1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 04-03-2011 View substance registered dossier
1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 27-10-2010 View substance registered dossier
1,3-dioxo-2,3-dihydro-1H-benzo[5,10]anthra[2,1,9-def]isoquinoline-8-sulfonic acid
428-540-6 - Active NONS Individual Tonnage data confidential 27-07-2011 View substance registered dossier
1,3-Dioxolane, 4,5-dichloro-2,2,4-trifluoro-5-(trifluoromethoxy)-
605-262-5 161611-73-0 Active Intermediate Individual Intermediate use only 22-09-2021 View substance registered dossier
1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-(4-methylbenzenesulfonate), (2R,4R)-rel-
603-791-6 134071-44-6 Cease Manufacture Intermediate Individual Cease manufacture 26-01-2015 View substance registered dossier
1,3-Naphthalenedisulfonic acid, 7-[2-[4-[[4-[2-[2-(cyanoamino)-1,6-dihydro-4-hydroxy-6-oxo-5-pyrimidinyl]diazenyl]benzoyl]amino]-3-methoxyphenyl]diazenyl]-, sodium salt (1:2)
931-147-7 1333467-33-6 Active Intermediate Individual Intermediate use only 08-07-2010 View substance registered dossier
1,3-phenylenebis((4-hydroxyphenyl)methanone)
816-325-3 5436-05-5 Active Full Individual ≥ 10 to < 100 tonnes 20-03-2020 View substance registered dossier
1,3-phenylenebis(oxyethane-2,1-diyl) dihexadecanoate
807-889-1 1255203-42-9 Active Full Individual ≥ 1 to < 10 tonnes 02-06-2016 View substance registered dossier
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate
931-295-2 - Active Full Individual ≥ 1 000 to < 10 000 tonnes 31-03-2020 View substance registered dossier
1,3-Propanediamine, N-[3-(C11-14-branched alkyloxy)propyl] derivs.
932-122-3 1334421-88-3 Active Intermediate Individual Intermediate use only 02-07-2020 View substance registered dossier
1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched
270-851-2 68479-04-9 Active Intermediate Individual Intermediate use only 28-03-2014 View substance registered dossier
1,3-Propanediamine, N1-[2-[2-(dimethylamino)ethoxy]ethyl]-N1-methyl-
470-720-1 189253-72-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Lonza Biologics PLC The Courtyard, Severn Drive GL20 8GD Tewkesbury Gloucestershire United Kingdom United Kingdom No longer Valid 1,3-dichloro-5-ethyl-5-methylimidazolidine-2,4-dione 401-570-7 89415-87-2 2021 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,3-dichlorobenzene 208-792-1 541-73-1 - View substance registered dossier
ARLANXEO Deutschland GmbH Alte Heerstraße 2 41540 Dormagen Germany Germany Active 1,3-dichlorobut-2-ene 213-138-3 926-57-8 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active 1,3-dichloropropan-2-ol 202-491-9 96-23-1 - View substance registered dossier
[Confidential] - - - 1,3-dichloropropane 205-531-3 142-28-9 - View substance registered dossier
SOCIETA' CHIMICA BUSSI S.P.A. Piazzale Elettrochimica 1 65022 Bussi sul Tirino Italy Italy Active 1,3-dihydro-1,3-dioxo-2H-isoindole-2-hexanoic acid 224-675-8 4443-26-9 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione 253-326-2 37052-78-1 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione 253-326-2 37052-78-1 2013 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid 1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate 605-637-3 172529-93-0 2021 View substance registered dossier
LABSO Chimie Fine 20, rue Jean Duvert 33920 Blanquefort France France Cease Manufacture 1,3-Dioxan-2-one 423-980-5 - 2016 View substance registered dossier
Sabinsa Europe GmbH Monzastrasse 4 63225 Langen Hessen Germany Germany Active 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- - 117933-89-8 - View substance registered dossier
V. MANE FILS 620 route de Grasse 06620 Le Bar sur Loup France France Active 1,3-dioxane, 2-(3,3-dimethyl-1-cyclohexen-1-yl)-2,5,5-trimethyl 815-500-1 1853175-99-1 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)- 700-258-0 125971-95-1 - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)- 700-258-0 125971-95-1 2011 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)- 700-258-0 125971-95-1 2008; 2010 View substance registered dossier
BASF Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 1,3-dioxo-2,3-dihydro-1H-benzo[5,10]anthra[2,1,9-def]isoquinoline-8-sulfonic acid 428-540-6 - 2011 View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 1,3-Dioxolane, 4,5-dichloro-2,2,4-trifluoro-5-(trifluoromethoxy)- 605-262-5 161611-73-0 2021 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture 1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-(4-methylbenzenesulfonate), (2R,4R)-rel- 603-791-6 134071-44-6 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 1,3-Naphthalenedisulfonic acid, 7-[2-[4-[[4-[2-[2-(cyanoamino)-1,6-dihydro-4-hydroxy-6-oxo-5-pyrimidinyl]diazenyl]benzoyl]amino]-3-methoxyphenyl]diazenyl]-, sodium salt (1:2) 931-147-7 1333467-33-6 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 1,3-phenylenebis((4-hydroxyphenyl)methanone) 816-325-3 5436-05-5 2020 View substance registered dossier
[Confidential] - - - 1,3-phenylenebis(oxyethane-2,1-diyl) dihexadecanoate 807-889-1 1255203-42-9 - View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 - S-44485 Stenungsund - Sweden Sweden Active 1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - 2011; 2013; 2014; 2015; 2020 View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 - S-44485 Stenungsund - Sweden Sweden Active 1,3-Propanediamine, N-[3-(C11-14-branched alkyloxy)propyl] derivs. 932-122-3 1334421-88-3 2020 View substance registered dossier
Global Amines Germany GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched 270-851-2 68479-04-9 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1,3-Propanediamine, N1-[2-[2-(dimethylamino)ethoxy]ethyl]-N1-methyl- 470-720-1 189253-72-3 - View substance registered dossier

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