Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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First published date:
Last update date:
Substance data
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Uses and exposure
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Details
L 128
418-460-1 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
L 708,350
417-380-2 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
L 754,188
417-390-7 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
L-2-(Benzyl-methyl-amino)-1-(3-hydroxy-phenyl)-ethanol
922-676-4 - Cease Manufacture Intermediate Individual Cease manufacture 20-11-2012 View substance registered dossier
L-Alanine, 1-methylethyl ester, hydrochloride (1:1)
692-724-4 62062-65-1 Active Intermediate Individual Intermediate use only 01-10-2015 View substance registered dossier
L-alpha-glutamyltryptamine
441-180-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
L-arginine phosphate
949-986-2 49720-39-0 Active Full Individual ≥ 10 to < 100 tonnes 22-05-2020 View substance registered dossier
L-Ascorbic acid 2-glucoside
425-980-0 129499-78-1 Active Full Individual ≥ 1 to < 10 tonnes 05-06-2013 View substance registered dossier
L-Ascorbic acid, 2-(dihydrogen phosphate), sodium salt (1:3)
425-180-1 66170-10-3 Active Full Individual ≥ 0 to < 10 tonnes 20-12-2013 View substance registered dossier
L-Aspartic acid, N,N'-1,2-ethanediylbis-
439-840-1 20846-91-7 Active Full Individual ≥ 100 to < 1 000 tonnes 11-01-2013 View substance registered dossier
L-Glutamic acid, N-acetyl-, compd. with (.alpha.S)-.alpha.-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine (1:1)
606-883-4 219921-94-5 Active Intermediate Individual Intermediate use only 10-12-2014 View substance registered dossier
L-Leucine, 4-fluoro-N-[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]-, compd. with N-cyclohexylcyclohexanamine (1:1)
700-778-8 1064076-86-3 Active Full Individual ≥ 1 to < 10 tonnes 23-02-2012 View substance registered dossier
L-Lysine, N2,N6-bis[N-(1-oxododecyl)glutamyl]-, sodium salt (1:?)
688-011-2 1243654-79-6 Active Full Individual ≥ 1 to < 10 tonnes 29-10-2012 View substance registered dossier
L-Ornithine, fermentation products
924-152-0 - Active Intermediate Individual Intermediate use only 13-05-2013 View substance registered dossier
L-threo-a-D-galacto-Octopyranoside, methyl-7-chloro-6,7,8-trideoxy-3,4-O-(1-methylethyliden)-6-[[[(2S,4R)-1-methyl-4-propyl-2-pirrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
602-998-9 124547-63-3 Active Intermediate Individual Intermediate use only 18-01-2018 View substance registered dossier
L-threonine, fermentation products byproduct
923-725-2 - Active Full Individual ≥ 1 000 to < 10 000 tonnes 29-10-2013 View substance registered dossier
L-Tyrosine, N-acetyl-3,5-diamino-O-(4-methoxyphenyl)-, ethyl ester
815-855-2 440667-78-7 Active Full Individual ≥ 1 to < 10 tonnes 16-06-2021 View substance registered dossier
L-Tyrosine, N-acetyl-3,5-dinitro-, etyhl ester
815-707-7 29358-99-4 Active Full Individual ≥ 1 to < 10 tonnes 02-10-2021 View substance registered dossier
L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester
604-047-3 137863-20-8 Active Full Individual ≥ 100 to < 1 000 tonnes 21-05-2019 View substance registered dossier
L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
610-513-7 502421-44-5 Active Intermediate Individual Intermediate use only 03-10-2011 View substance registered dossier
LANTHANUM STRONTIUM MANGANESE OXIDE
454-770-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Lauroyl chloride
203-941-7 112-16-3 Active Intermediate Individual Intermediate use only 07-10-2013 View substance registered dossier
LAUROYL-BETA-ALANIN
410-320-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LAURYL ITACONYL PROPYL-3-SODIUM SULFONATE
443-820-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LC 270
426-310-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LC-SILICON-PIGMENT
418-890-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Leach of products of roasting of "slags, steelmaking, vanadium
919-559-5 - Active Intermediate Individual Intermediate use only 07-11-2019 View substance registered dossier
Lead chloride hydroxides, recovery products from lead and bismuth chemicals manufacturing
947-517-6 - Active Intermediate Individual Intermediate use only 18-05-2018 View substance registered dossier
Lead dioxide 215-174-5 1309-60-0 Active Full Individual ≥ 1 to < 10 tonnes 04-09-2018 View substance registered dossier
Lead tetraacetate 208-908-0 546-67-8 Cease Manufacture Full Individual Cease manufacture 02-11-2010 View substance registered dossier
LEATHER BROWN JF 263/2
439-230-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LEPTOSPERMUM SCOPARIUM OIL
425-630-7 223749-44-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LEUCOPHOR 8407E
400-500-2 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
LEVAFIX OLIV E-GLA
405-590-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LEVODION
442-550-8 - Cease Manufacture NONS Individual Cease manufacture 12-01-2012 View substance registered dossier
LEXMARK ACRYLIC COPOLYMER
420-880-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LICA 09
418-130-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
LICORIS
427-660-6 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Liraglutide precursor
944-552-9 - Active Full Individual ≥ 10 to < 100 tonnes 29-09-2017 View substance registered dossier
Lithium (C8-C10, branched, C9 rich, alkylnaphthalene sulphonate)
943-938-4 28214-91-7 Active Full Individual ≥ 1 to < 10 tonnes 06-10-2016 View substance registered dossier
Lithium 2-aminobenzothiazole-6-sulphonate
265-367-3 65072-36-8 Active Full Individual ≥ 1 to < 10 tonnes 03-01-2020 View substance registered dossier
lithium 3-((3,4-dicyanophenyl)sulfonyl)propane-1-sulfonate)
700-777-2 - No longer Valid Full Individual No longer valid 24-06-2020 View substance registered dossier
lithium 3-((3,4-dicyanophenyl)thio)propane-1-sulfonate
700-787-7 769953-18-6 No longer Valid Full Individual No longer valid 11-08-2014 View substance registered dossier
lithium 3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-ide
829-217-6 1449413-05-1 Active Intermediate Individual Intermediate use only 05-11-2018 View substance registered dossier
Lithium 3-oxo-1,2(2H)-benzisothiazol-2-ide
411-690-1 111337-53-2 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
lithium 4,5-dicyano-2-(trifluoromethyl)imidazol-1-ide
691-963-1 761441-54-7 Active Full Individual ≥ 1 to < 10 tonnes 06-05-2015 View substance registered dossier
Lithium dihydrogen 5-sulphonatoisophthalate
256-275-4 46728-75-0 Active Full Individual ≥ 1 to < 10 tonnes 04-06-2021 View substance registered dossier
lithium hydrogen 7-{(E)-[2-amino-4-(2-naphthyl)-1,3-thiazol-5-yl]diazenyl}naphthalene-1,3,5-trisulfonate (2:1:1)
940-433-0 - No longer Valid Full Individual No longer valid 06-08-2018 View substance registered dossier
Lithium isopropoxide
424-140-0 2388-10-5 Active Intermediate Individual Intermediate use only 15-12-2010 View substance registered dossier
Lithium naphthalene-2-carboxylate
700-040-5 674347-28-5 Active Full Individual ≥ 1 to < 10 tonnes 12-06-2009 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - L 128 418-460-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active L 708,350 417-380-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active L 754,188 417-390-7 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture L-2-(Benzyl-methyl-amino)-1-(3-hydroxy-phenyl)-ethanol 922-676-4 - 2019 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active L-Alanine, 1-methylethyl ester, hydrochloride (1:1) 692-724-4 62062-65-1 - View substance registered dossier
- - - - L-alpha-glutamyltryptamine 441-180-4 - - View substance registered dossier
Arevo AB Dåva Energiväg 8 905 95 Umeå Västerbottens Län Sweden Sweden Active L-arginine phosphate 949-986-2 49720-39-0 2020 View substance registered dossier
KTR Europe GmbH Mergenthalerallee 77 D-65760 Eschborn Germany Germany Active L-Ascorbic acid 2-glucoside 425-980-0 129499-78-1 - View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany Germany Active L-Ascorbic acid, 2-(dihydrogen phosphate), sodium salt (1:3) 425-180-1 66170-10-3 - View substance registered dossier
Innospec Performance Chemicals France SAS (Only Rep 2) Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France France Active L-Aspartic acid, N,N'-1,2-ethanediylbis- 439-840-1 20846-91-7 2012; 2013 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active L-Glutamic acid, N-acetyl-, compd. with (.alpha.S)-.alpha.-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine (1:1) 606-883-4 219921-94-5 - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active L-Leucine, 4-fluoro-N-[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]-, compd. with N-cyclohexylcyclohexanamine (1:1) 700-778-8 1064076-86-3 - View substance registered dossier
Covance Clinical Development SA 150 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active L-Lysine, N2,N6-bis[N-(1-oxododecyl)glutamyl]-, sodium salt (1:?) 688-011-2 1243654-79-6 2012 View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Active L-Ornithine, fermentation products 924-152-0 - - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active L-threo-a-D-galacto-Octopyranoside, methyl-7-chloro-6,7,8-trideoxy-3,4-O-(1-methylethyliden)-6-[[[(2S,4R)-1-methyl-4-propyl-2-pirrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride 602-998-9 124547-63-3 - View substance registered dossier
Evonik Agroferm Zrt. Nádudvari útfél 4183 Kaba Hungary Hungary Active L-threonine, fermentation products byproduct 923-725-2 - 2013 View substance registered dossier
Peptido GmbH Am Kraftwerk 6 66450 Bexbach Germany Germany Active L-Tyrosine, N-acetyl-3,5-diamino-O-(4-methoxyphenyl)-, ethyl ester 815-855-2 440667-78-7 - View substance registered dossier
Peptido GmbH Am Kraftwerk 6 66450 Bexbach Germany Germany Active L-Tyrosine, N-acetyl-3,5-dinitro-, etyhl ester 815-707-7 29358-99-4 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester 604-047-3 137863-20-8 2013; 2014; 2019 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester 610-513-7 502421-44-5 - View substance registered dossier
Höganäs Germany GmbH Im Schleeke 78-91 38642 Goslar Germany Germany Active LANTHANUM STRONTIUM MANGANESE OXIDE 454-770-1 - - View substance registered dossier
Croda EU B.V. (OR8) Buurtje 1 2802 BE Gouda Netherlands Netherlands Active Lauroyl chloride 203-941-7 112-16-3 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active LAUROYL-BETA-ALANIN 410-320-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active LAURYL ITACONYL PROPYL-3-SODIUM SULFONATE 443-820-8 - - View substance registered dossier
- - - - LC 270 426-310-1 - - View substance registered dossier
SICPA Germany GmbH Gewerbepark Lindach D7 84489 Burghausen Germany Germany Active LC-SILICON-PIGMENT 418-890-8 - - View substance registered dossier
Treibacher Industrie AG Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria Austria Active Leach of products of roasting of "slags, steelmaking, vanadium 919-559-5 - 2009; 2011; 2019 View substance registered dossier
5N Plus Belgium SA rue de la station, 67 1495 Tilly Région wallonne Belgium Belgium Active Lead chloride hydroxides, recovery products from lead and bismuth chemicals manufacturing 947-517-6 - - View substance registered dossier
Quality Chemicals S.L. C/ Fornal, 35, Pol. Ind. Can Comelles-Sud 08292 Esparreguera Barcelona Spain Spain Active Lead dioxide 215-174-5 1309-60-0 2018 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture Lead tetraacetate 208-908-0 546-67-8 2019 View substance registered dossier
- - - - LEATHER BROWN JF 263/2 439-230-5 - - View substance registered dossier
- - - - LEPTOSPERMUM SCOPARIUM OIL 425-630-7 223749-44-8 - View substance registered dossier
Archroma UK, Ltd 1 Bartholomew Lane EC2N 2AX London United Kingdom United Kingdom No longer Valid LEUCOPHOR 8407E 400-500-2 - 2021 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active LEVAFIX OLIV E-GLA 405-590-7 - - View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Cease Manufacture LEVODION 442-550-8 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active LEXMARK ACRYLIC COPOLYMER 420-880-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active LICA 09 418-130-5 - - View substance registered dossier
- - - - LICORIS 427-660-6 - - View substance registered dossier
Novo Nordisk A/S Novo Alle 2880 Bagsværd Denmark Denmark Active Liraglutide precursor 944-552-9 - - View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active Lithium (C8-C10, branched, C9 rich, alkylnaphthalene sulphonate) 943-938-4 28214-91-7 2016 View substance registered dossier
LinmarkOR95 Linmark Consulting Ltd Hillock, Ballut Street STJ 1373 St Julian's Malta Malta Active Lithium 2-aminobenzothiazole-6-sulphonate 265-367-3 65072-36-8 2020 View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid lithium 3-((3,4-dicyanophenyl)sulfonyl)propane-1-sulfonate) 700-777-2 - 2021 View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid lithium 3-((3,4-dicyanophenyl)thio)propane-1-sulfonate 700-787-7 769953-18-6 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active lithium 3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-ide 829-217-6 1449413-05-1 - View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Cease Manufacture Lithium 3-oxo-1,2(2H)-benzisothiazol-2-ide 411-690-1 111337-53-2 2020 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active lithium 4,5-dicyano-2-(trifluoromethyl)imidazol-1-ide 691-963-1 761441-54-7 - View substance registered dossier
Ascend Performance Materials srpl/bvba Watson & Crick Hill Park 11, rue Granbonpré - Bâtiment H B-1348 Louvain-la-Neuve Walloon Brabant Belgium Belgium Active Lithium dihydrogen 5-sulphonatoisophthalate 256-275-4 46728-75-0 2021 View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid lithium hydrogen 7-{(E)-[2-amino-4-(2-naphthyl)-1,3-thiazol-5-yl]diazenyl}naphthalene-1,3,5-trisulfonate (2:1:1) 940-433-0 - 2021 View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active Lithium isopropoxide 424-140-0 2388-10-5 2010 View substance registered dossier
TÜV SÜD Industrie Service GmbH Westendstraße 199 80686 München Germany Germany Active Lithium naphthalene-2-carboxylate 700-040-5 674347-28-5 - View substance registered dossier

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