Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
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  • Formulation or re-packing
  • Uses at industrial sites
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Category:
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Details
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
429-080-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
TERT-BUTYL 4-({[6-AMINO-5-(4-PHENOXYPHENYL)PYRIMIDIN-4-YL]AMINO}METHYL)-4-FLUOROPIPERIDINE-1-CARBOXYLATE
941-339-2 - Active Intermediate Joint Intermediate use only 21-06-2021 View substance registered dossier
tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate
954-331-9 - Active Intermediate Joint Intermediate use only 21-06-2021 View substance registered dossier
tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate
920-979-6 - Active Intermediate Joint Intermediate use only 15-02-2013 View substance registered dossier
tert-butyl N-[(E)-(4-pyridin-2-ylphenyl)methylideneamino]carbamate
918-454-1 - Active Intermediate Joint Intermediate use only 08-03-2018 View substance registered dossier
Tert-butyl tert-butyldimethylsilyl [(2S)-2-(benzyloxy)propylidene]carbonohydrazonate
925-662-6 - Active Intermediate Individual Intermediate use only 22-10-2018 View substance registered dossier
tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate
431-870-3 - Active Full Joint ≥ 1 to < 10 tonnes 31-07-2017 View substance registered dossier
tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate
431-870-3 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate
431-870-3 - Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
tert-butyl {(1S,3S)-3-{(S)- hydroxy[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methyl-1-[ (2S,4S)-5-oxo-4-(propan-2-yl)tetrahydrofuran-2-yl ]pentyl}carbamate
700-317-0 - No longer Valid Intermediate Individual No longer valid 01-02-2010 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate 429-080-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active TERT-BUTYL 4-({[6-AMINO-5-(4-PHENOXYPHENYL)PYRIMIDIN-4-YL]AMINO}METHYL)-4-FLUOROPIPERIDINE-1-CARBOXYLATE 941-339-2 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate 954-331-9 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate 920-979-6 - 2013 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active tert-butyl N-[(E)-(4-pyridin-2-ylphenyl)methylideneamino]carbamate 918-454-1 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active Tert-butyl tert-butyldimethylsilyl [(2S)-2-(benzyloxy)propylidene]carbonohydrazonate 925-662-6 - - View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - 2010; 2016; 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - - View substance registered dossier
Bakhu Pharma Ltd 34 Thursby Road Croft Business Park CH62 3PW Bromborough Wirral United Kingdom United Kingdom No longer Valid tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active tert-butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate 431-870-3 - 2018 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid tert-butyl {(1S,3S)-3-{(S)- hydroxy[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methyl-1-[ (2S,4S)-5-oxo-4-(propan-2-yl)tetrahydrofuran-2-yl ]pentyl}carbamate 700-317-0 - 2021 View substance registered dossier

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