Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:



Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
No results were found
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride
433-010-2 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate
942-159-7 - Cease Manufacture Intermediate Individual Cease manufacture 20-07-2015 View substance registered dossier
(tert-Butoxycarbonyl)methyl 2-[1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl]acetate
616-210-6 75302-98-6 Cease Manufacture Intermediate Individual Cease manufacture 17-10-2012 View substance registered dossier
(trimethoxysilyl)methyl prop-2-enoate
700-313-9 21134-38-3 Cease Manufacture Intermediate Individual Cease manufacture 18-11-2009 View substance registered dossier
429-330-7 - Cease Manufacture Intermediate Individual Cease manufacture 03-02-2012 View substance registered dossier
700-075-6 218768-11-7 Cease Manufacture Intermediate Individual Cease manufacture 11-11-2008 View substance registered dossier
(Z)-5-Amino-.alpha.-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid
456-150-6 - Cease Manufacture NONS Individual Cease manufacture 04-03-2011 View substance registered dossier
700-902-0 1370699-98-1 Cease Manufacture Full Joint Cease manufacture 29-01-2019 View substance registered dossier
(±)-2-(6-methoxy-2-naphthyl)propionic acid
247-485-7 26159-31-9 Cease Manufacture Intermediate Joint Cease manufacture 10-09-2013 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
AstraZeneca B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden Sweden Cease Manufacture (S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride 433-010-2 - 2012 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate 942-159-7 - 2017 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture (tert-Butoxycarbonyl)methyl 2-[1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl]acetate 616-210-6 75302-98-6 2021 View substance registered dossier
Dow Silicones Belgium SPRL OR-1 rue Jules Bordet Parc industriel C 7180 Seneffe Belgium Belgium Cease Manufacture (trimethoxysilyl)methyl prop-2-enoate 700-313-9 21134-38-3 2012 View substance registered dossier
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Cease Manufacture (TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE 429-330-7 - 2014 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (Z)-4-hydroxy-4-(6-methoxynaphthalen-2-yl)but-3-en-2-one 700-075-6 218768-11-7 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (Z)-5-Amino-.alpha.-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid 456-150-6 - 2021 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Cease Manufacture (±)-1-(5-propyl-1,3-benzodioxol-2-yl)-1-ethanone 700-902-0 1370699-98-1 2020 View substance registered dossier
Stadex Nederland BV Boxbergerweg 119 7431PM Diepenveen Netherlands Netherlands Cease Manufacture (±)-2-(6-methoxy-2-naphthyl)propionic acid 247-485-7 26159-31-9 2013 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture (±)-2-(6-methoxy-2-naphthyl)propionic acid 247-485-7 26159-31-9 2019 View substance registered dossier

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