Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
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Details
4-{6-[(methylsulfonyl)oxy]-1-benzothiophen-2-yl}phenyl methanesulfonate
806-588-2 84449-65-0 Active Intermediate Joint Intermediate use only 08-06-2016 View substance registered dossier
4-{6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl}aniline
687-781-7 152828-25-6 Active Intermediate Joint Intermediate use only 18-07-2019 View substance registered dossier
4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid
926-027-6 - Active Intermediate Joint Intermediate use only 08-07-2019 View substance registered dossier
4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one
828-315-6 1443532-21-5 Active Intermediate Individual Intermediate use only 22-11-2019 View substance registered dossier
4H-1,2,4-triazol-4-ylamine
209-533-5 584-13-4 Active Intermediate Individual Intermediate use only 31-05-2016 View substance registered dossier
4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester
605-256-2 16150-45-1 Active Intermediate Joint Intermediate use only 04-04-2018 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 25-01-2018 View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione
204-255-0 118-48-9 Active Intermediate Joint Intermediate use only 09-07-2021 View substance registered dossier
4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1)
601-635-1 119812-29-2 Active Intermediate Individual Intermediate use only 15-02-2013 View substance registered dossier
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester
620-286-6 59469-49-7 Active Intermediate Individual Intermediate use only 10-11-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-{6-[(methylsulfonyl)oxy]-1-benzothiophen-2-yl}phenyl methanesulfonate 806-588-2 84449-65-0 2016 View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active 4-{6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl}aniline 687-781-7 152828-25-6 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid 926-027-6 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one 828-315-6 1443532-21-5 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 4H-1,2,4-triazol-4-ylamine 209-533-5 584-13-4 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester 605-256-2 16150-45-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester 605-256-2 16150-45-1 2016 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester 605-256-2 16150-45-1 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 2010; 2013; 2016 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
LUMINOCHEM Kutató-Fejlesztő Kft. Háros utca 7/a 1222 Budapest Hungary Hungary Active 4H-3,1-benzoxazine-2,4(1H)-dione 204-255-0 118-48-9 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany Germany Active 4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1) 601-635-1 119812-29-2 2013 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester 620-286-6 59469-49-7 - View substance registered dossier

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