Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 17,201 - 17,300 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd	604-491-8	145767-92-6	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
4-trans-Propionylcyclohexylbenzol	618-109-2	88069-93-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	13-11-2017	View substance registered dossier
4-trans-Propylcyclohexylbenzene	612-101-2	61203-94-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	11-12-2012	View substance registered dossier
4-vinylcyclohexene	202-848-9	100-40-3	Active	Intermediate	Joint	Intermediate use only	11-07-2017	View substance registered dossier
4-{(E)-[1-(anilinocarbonyl)-2-oxopropyl]diazenyl}benzoic acid	603-014-0	124772-04-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-05-2015	View substance registered dossier
4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one hydrochloride	618-311-0	898543-06-1	Active	Intermediate	Joint	Intermediate use only	16-12-2022	View substance registered dossier
4-{6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl}aniline	687-781-7	152828-25-6	Active	Intermediate	Joint	Intermediate use only	18-07-2019	View substance registered dossier
4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid	926-027-6	-	Active	Intermediate	Joint	Intermediate use only	08-07-2019	View substance registered dossier
4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one	828-315-6	1443532-21-5	Active	Intermediate	Individual	Intermediate use only	22-11-2019	View substance registered dossier
4H-1,2,4-triazol-4-ylamine	209-533-5	584-13-4	Active	Intermediate	Individual	Intermediate use only	31-05-2016	View substance registered dossier
4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester	605-256-2	16150-45-1	Active	Intermediate	Joint	Intermediate use only	04-04-2018	View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	Active	Intermediate	Joint	Intermediate use only	25-01-2018	View substance registered dossier
4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	Active	Intermediate	Joint	Intermediate use only	09-07-2021	View substance registered dossier
4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1)	601-635-1	119812-29-2	Active	Intermediate	Individual	Intermediate use only	15-02-2013	View substance registered dossier
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester	620-286-6	59469-49-7	Active	Intermediate	Individual	Intermediate use only	10-11-2016	View substance registered dossier
4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol	943-142-7	-	Active	Intermediate	Joint	Intermediate use only	08-04-2021	View substance registered dossier
4’-(2-Propyl-4-methyl-6-(1-methylbenzimidazolyl-2-yl)-benzimidazol-1-ylmethyl)biphenyl-2-carbonsäure Hydrochlorid	485-140-4	-	Active	Intermediate	Individual	Intermediate use only	18-12-2012	View substance registered dossier
5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid	629-877-3	376592-57-3	Active	Intermediate	Individual	Intermediate use only	30-05-2018	View substance registered dossier
5'-chloro-2'-methoxy-[1,1'-biphenyl]-3-carboxylic acid	825-843-9	1170133-64-8	Active	Intermediate	Individual	Intermediate use only	30-05-2018	View substance registered dossier
5'-chloro-2'-methoxyacetoacetanilide	258-189-2	52793-11-0	Active	Intermediate	Joint	Intermediate use only	14-05-2018	View substance registered dossier
5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide	202-182-9	92-72-8	Active	Intermediate	Joint	Intermediate use only	02-10-2018	View substance registered dossier
5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide	205-207-1	135-63-7	Active	Intermediate	Joint	Intermediate use only	07-12-2017	View substance registered dossier
5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one monohydrochloride	812-545-9	93173-05-8	Active	Intermediate	Joint	Intermediate use only	01-02-2017	View substance registered dossier
5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one	212-944-2	885-70-1	Active	Intermediate	Individual	Intermediate use only	05-10-2020	View substance registered dossier
5,5'-((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-2-((S)-pyrrolidin-2-yl)-1H-benzo[d]imidazole)	826-675-9	1332357-14-8	Active	Intermediate	Joint	Intermediate use only	02-06-2020	View substance registered dossier
5,5'-(Ethane-1,2-diylbis(sulfanediyl))bis(1,3,4-thiadiazol-2-amine)	941-658-7	82875-12-5	No longer Valid	Intermediate	Individual	No longer valid	30-07-2019	View substance registered dossier
5,5'-dimethoxy-3,3'-di-tert.-butyl-1,1'-biphenyl-2,2'-diol	604-200-4	14078-41-2	Active	Intermediate	Joint	Intermediate use only	04-03-2020	View substance registered dossier
5,5,5',5'-Tetramethyl-2,2'-bi(1,3,2-dioxaborinane)	639-407-9	201733-56-4	Active	Intermediate	Joint	Intermediate use only	12-05-2020	View substance registered dossier
5,5-DIMETHYL-2-ISOPROPYLTHIAZOLIDINE	603-850-6	134695-88-8	No longer Valid	Intermediate	Individual	No longer valid	17-05-2016	View substance registered dossier
5,5-dimethyl-2-propan-2-yl-2H-1,3-thiazole	608-796-7	32899-85-7	No longer Valid	Intermediate	Individual	No longer valid	17-05-2016	View substance registered dossier
5,5-dimethylcyclohexane-1,3-dione	204-804-4	126-81-8	Active	Intermediate	Joint	Intermediate use only	21-11-2022	View substance registered dossier
5,5-dimethylhydantoin	201-051-3	77-71-4	Active	Intermediate	Joint	Intermediate use only	21-11-2019	View substance registered dossier
5,5-pentamethylene-7-oxo-2,3,4,5,6,7-hexahydrocyclopenta[a] pyrimidine	922-971-8	-	Active	Intermediate	Joint	Intermediate use only	16-10-2017	View substance registered dossier
5,6 beta-Epoxy-7 beta-hydroxy-15 beta,16 beta-methylene-3 beta-pivaloyloxy-5 beta-androstan-17-one	617-351-6	82544-13-6	Active	Intermediate	Joint	Intermediate use only	13-09-2022	View substance registered dossier
5,6,7,8-tetrahydroquinoline	234-030-2	10500-57-9	Active	Intermediate	Joint	Intermediate use only	13-11-2018	View substance registered dossier
5,6-Dichloro-pyrimidin-4-ylamine	815-619-9	310400-38-5	Active	Intermediate	Joint	Intermediate use only	28-07-2021	View substance registered dossier
5,6-diethylindan-2-aminium chloride	455-940-8	-	Active	Intermediate	Joint	Intermediate use only	05-01-2015	View substance registered dossier
5,6-Dihydro-2-[trans,trans-4'-propyl(1,1'-bicyclohexyl-4-yl)-4H-1,3-dithiin-1-iumtrifluoromethanesulfonate	609-186-3	358732-12-4	Active	Intermediate	Joint	Intermediate use only	24-11-2022	View substance registered dossier
5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1h,4h)-dione	695-944-9	92260-81-6	Active	Intermediate	Joint	Intermediate use only	25-05-2022	View substance registered dossier
5,6-dimethoxyindoline	927-137-7	15937-07-2	Active	Intermediate	Joint	Intermediate use only	05-06-2018	View substance registered dossier
5,6-dimethylbenzimidazole	209-488-1	582-60-5	Active	Intermediate	Joint	Intermediate use only	25-01-2022	View substance registered dossier
5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	Active	Intermediate	Joint	Intermediate use only	22-07-2020	View substance registered dossier
5,7-diazaspiro[3.4]octane-6,8-dione	618-291-3	89691-88-3	Active	Intermediate	Joint	Intermediate use only	18-03-2020	View substance registered dossier
5,7-dichloro-4-hydroxyquinoline-3-carboxylic acid ODCQA	431-250-2	171850-30-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	23-10-2015	View substance registered dossier
5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-amine	603-562-0	13223-43-3	No longer Valid	Intermediate	Joint	No longer valid	24-10-2011	View substance registered dossier
5,8-bis(carboxymethyl)]-11-[2-(methylamino)-2-oxoethyl]-3-oxo-2,5,8,11-tetreazatridecan-13-oic acid	601-640-9	119895-95-3	Active	Intermediate	Individual	Intermediate use only	05-10-2017	View substance registered dossier
5,8-dihydro-1-naphthol	248-596-3	27673-48-9	Active	Intermediate	Joint	Intermediate use only	11-07-2019	View substance registered dossier
5,8-Dihydro-1-naphthyl acetate	610-759-5	51927-56-1	Active	Intermediate	Individual	Intermediate use only	27-10-2017	View substance registered dossier
5-(1-Hydroxy-2-{[1-(4-hydroxyphenyl)-2-propanyl]amino}ethyl)-1,3-benzenediol	680-817-2	13392-18-2	Cease Manufacture	Intermediate	Individual	Cease manufacture	19-02-2016	View substance registered dossier
5-(1-methyl-4-piperidyl)-5H-dibenzo[a,d]cyclohepten-5-ol hydrochloride	223-746-0	4046-24-6	Active	Intermediate	Joint	Intermediate use only	25-01-2018	View substance registered dossier
5-(1-methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol	609-737-8	3967-32-6	Active	Intermediate	Joint	Intermediate use only	10-02-2017	View substance registered dossier
5-(1H-1,2,4-Triazol-1ylmethyl)-1H-indole-3-ethanol	620-292-9	160194-39-8	Active	Intermediate	Joint	Intermediate use only	09-03-2020	View substance registered dossier
5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole	845-721-9	1443623-92-4	Active	Intermediate	Individual	Intermediate use only	19-11-2019	View substance registered dossier
5-(2-bromoacetyl)-1,3-phenylene diacetate	253-193-0	36763-39-0	Active	Intermediate	Joint	Intermediate use only	27-05-2016	View substance registered dossier
5-(2-chloroethyl)-4-methyl-1,3-thiazole hydrochloride (1:1)	611-928-6	6001-74-7	Active	Intermediate	Individual	Intermediate use only	16-07-2012	View substance registered dossier
5-(2-chloroethyl)-4-methyl-1,3-thiazole hydrochloride (1:1)	611-928-6	6001-74-7	Active	Intermediate	Individual	Intermediate use only	11-07-2013	View substance registered dossier
5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione	855-578-4	1150560-59-0	Active	Intermediate	Joint	Intermediate use only	25-06-2020	View substance registered dossier
5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde	807-719-6	881677-11-8	Active	Intermediate	Joint	Intermediate use only	13-08-2021	View substance registered dossier
5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde	809-913-6	881674-56-2	Active	Intermediate	Joint	Intermediate use only	05-08-2022	View substance registered dossier
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile	809-912-0	1240948-77-9	Active	Intermediate	Joint	Intermediate use only	02-03-2022	View substance registered dossier
5-(3-Bromophenyl)pentanoic Acid	878-736-4	857480-35-4	Active	Intermediate	Joint	Intermediate use only	04-04-2022	View substance registered dossier
5-(3-chlorophenyl)-2-(2-methoxy-2-oxoethylcarbamoyl)pyrid-3-yl pivalate	947-757-1	-	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
5-(3-chlorophenyl)-3-hydroxypicolinic acid	825-120-8	1415226-40-2	Active	Intermediate	Joint	Intermediate use only	29-05-2018	View substance registered dossier
5-(3-chlorophenyl)-3-methoxypicolinonitrile	815-168-8	1415226-39-9	Active	Intermediate	Joint	Intermediate use only	13-07-2017	View substance registered dossier
5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol	214-594-6	1159-03-1	Active	Intermediate	Joint	Intermediate use only	10-02-2017	View substance registered dossier
5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	Active	Intermediate	Individual	Intermediate use only	08-05-2012	View substance registered dossier
5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	Active	Intermediate	Joint	Intermediate use only	03-05-2018	View substance registered dossier
5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	Active	Intermediate	Individual	Intermediate use only	26-04-2011	View substance registered dossier
5-(4-Brom-2-fluorphenylamino)-4-fluor-N-[2-(1,1-dimethylethoxy)ethoxy]-1-methyl-1H-benzo[d]imidazol-6-carboxamid	815-317-7	1604812-70-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	26-06-2020	View substance registered dossier
5-(4-bromo-2-fluoroanilino)-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid	815-319-8	1415564-99-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-04-2020	View substance registered dossier
5-(4-bromo-2-fluoroanilino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide	639-995-7	606143-89-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	31-07-2020	View substance registered dossier
5-(4-Bromophenyl)-4,6-dichloropyrimidine	807-547-1	146533-41-7	Active	Intermediate	Joint	Intermediate use only	14-09-2017	View substance registered dossier
5-(4-Bromophenyl)-4,6-dihydroxpyrimidine	814-997-2	706811-25-8	Active	Intermediate	Joint	Intermediate use only	03-10-2017	View substance registered dossier
5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole	616-036-0	73963-42-5	Active	Intermediate	Joint	Intermediate use only	19-08-2021	View substance registered dossier
5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole hydrochloride (1:1)	944-938-7	-	Active	Intermediate	Joint	Intermediate use only	18-07-2017	View substance registered dossier
5-(4-Hydroxymethyl-phenoxymethyl)-3-isopropyloxazolidin-2-one	926-787-9	-	Active	Intermediate	Individual	Intermediate use only	18-09-2017	View substance registered dossier
5-(4-hydroxyphenyl)imidazolidine-2,4-dione	219-340-8	2420-17-9	Active	Intermediate	Joint	Intermediate use only	10-11-2010	View substance registered dossier
5-(aminosulphonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide monohydrochloride	245-826-4	23694-14-6	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
5-(bromoacetyl)-1,3-phenylene bis(dimethylcarbamate)	279-805-6	81732-49-2	Active	Intermediate	Individual	Intermediate use only	21-05-2018	View substance registered dossier
5-(bromoacetyl)salicylamide	277-626-8	73866-23-6	Active	Intermediate	Joint	Intermediate use only	18-04-2018	View substance registered dossier
5-(difluoromethoxy)-1H-1,3-benzodiazole-2-thiol; 5-(difluoromethoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione	417-780-7	-	Active	Intermediate	Joint	Intermediate use only	17-05-2022	View substance registered dossier
5-(difluoromethoxy)-1H-1,3-benzodiazole-2-thiol; 5-(difluoromethoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione	417-780-7	-	Active	Intermediate	Individual	Intermediate use only	17-11-2014	View substance registered dossier
5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole	619-308-7	97963-62-7	Active	Intermediate	Joint	Intermediate use only	28-08-2018	View substance registered dossier
5-(dimethylamino)-2-nitrobenzoic acid	814-136-0	62876-66-8	Active	Intermediate	Joint	Intermediate use only	12-07-2017	View substance registered dossier
5-(hydroxymethyl)-2-furaldehyde	200-654-9	67-47-0	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-12-2018	View substance registered dossier
5-(Hydroxymethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	838-943-2	1182358-83-3	Active	Intermediate	Joint	Intermediate use only	29-05-2019	View substance registered dossier
5-(methoxymethyl)-2-furaldehyde	700-511-5	1917-64-2	Active	Intermediate	Joint	Intermediate use only	12-07-2013	View substance registered dossier
5-(methoxymethyl)pyridine-2,3-dicarboxylic acid	604-349-5	143382-03-0	Active	Intermediate	Individual	Intermediate use only	10-07-2014	View substance registered dossier
5-(Methylsulfonyl)pyridine-2-carbonitrile	682-451-9	848141-13-9	Cease Manufacture	Intermediate	Joint	Cease manufacture	28-08-2020	View substance registered dossier
5-(tert-butyl)oct-3-yne-2,5-diol	617-873-4	865205-28-3	Active	Intermediate	Joint	Intermediate use only	23-12-2022	View substance registered dossier
5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione	601-029-7	111025-46-8	Active	Intermediate	Joint	Intermediate use only	08-11-2019	View substance registered dossier
5-[(1E)-2-bromoethenyl]-2'-deoxy-, 3',5'-bis(4-chlorobenzoate) uridine	618-029-8	87531-10-0	Active	Intermediate	Joint	Intermediate use only	10-05-2016	View substance registered dossier
5-[(4-amino-1-naphthyl)azo]-2-anilinobenzenesulphonic acid	259-124-0	54363-79-0	Active	Intermediate	Joint	Intermediate use only	20-02-2018	View substance registered dossier
5-[(4-ethylpiperazin-1-yl)methyl]pyridine-2-amine	806-688-6	1180132-17-5	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
5-[(p-aminophenyl)azo]salicylic acid	202-948-2	101-51-9	Active	Intermediate	Joint	Intermediate use only	20-02-2018	View substance registered dossier
5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one	928-541-6	146939-27-7	Active	Intermediate	Joint	Intermediate use only	29-05-2018	View substance registered dossier
5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one; camphorsulphonic acid	806-795-8	909419-73-4	Active	Intermediate	Joint	Intermediate use only	10-04-2017	View substance registered dossier
5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide	926-076-3	-	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
5-[2-ethoxy-5-(4-methylpiperazin-1-ylsulphonyl)-phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-on	604-158-7	139755-83-2	Active	Intermediate	Individual	Intermediate use only	25-05-2018	View substance registered dossier
5-[3-(1-ethoxyethoxy)-3-methyl-4-penten-1-ynyl]-2,4,6,6-tetramethyl-5,6,7,7a-tetrahydro-1,3-benzodioxol-5-ol	605-301-6	162691-59-0	Active	Intermediate	Joint	Intermediate use only	11-05-2016	View substance registered dossier

Showing 17,201 - 17,300 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-trans-[4-trans-(3,4-Difluorphenyl)-cyclohexyl]-cyclohexancarbaldehyd	604-491-8	145767-92-6	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Cease Manufacture	4-trans-Propionylcyclohexylbenzol	618-109-2	88069-93-6	2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Cease Manufacture	4-trans-Propylcyclohexylbenzene	612-101-2	61203-94-9	2019	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	4-vinylcyclohexene	202-848-9	100-40-3	2016; 2017	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Cease Manufacture	4-{(E)-[1-(anilinocarbonyl)-2-oxopropyl]diazenyl}benzoic acid	603-014-0	124772-04-9	2019	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one hydrochloride	618-311-0	898543-06-1	2012; 2018; 2020; 2022	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	4-{6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl}aniline	687-781-7	152828-25-6	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid	926-027-6	-	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one	828-315-6	1443532-21-5	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	4H-1,2,4-triazol-4-ylamine	209-533-5	584-13-4	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester	605-256-2	16150-45-1	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester	605-256-2	16150-45-1	2016	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester	605-256-2	16150-45-1	2018	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	2010; 2013; 2016	View substance registered dossier
LUMINOCHEM Kutató-Fejlesztő Kft.	Háros utca 7/a 1222 Budapest Hungary	Hungary	Active	4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	-	View substance registered dossier
ACETO GmbH	Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany	Germany	Active	4H-Carbazol-4-one, 3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-, hydrochloride (1:1)	601-635-1	119812-29-2	2013	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-chloro-6-(2-fluorophenyl)-1-methyl-, ethyl ester	620-286-6	59469-49-7	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol	943-142-7	-	2021	View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U.	Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain	Spain	Active	4’-(2-Propyl-4-methyl-6-(1-methylbenzimidazolyl-2-yl)-benzimidazol-1-ylmethyl)biphenyl-2-carbonsäure Hydrochlorid	485-140-4	-	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid	629-877-3	376592-57-3	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	5'-chloro-2'-methoxy-[1,1'-biphenyl]-3-carboxylic acid	825-843-9	1170133-64-8	-	View substance registered dossier
Ferro Performance Pigments Belgium N.V.	Kortrijkstraat 153 8930 Menen Belgium	Belgium	Active	5'-chloro-2'-methoxyacetoacetanilide	258-189-2	52793-11-0	-	View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada)	Freundallee 9 a 30173 Hannover Germany	Germany	Active	5'-chloro-2'-methoxyacetoacetanilide	258-189-2	52793-11-0	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	5'-chloro-2'-methoxyacetoacetanilide	258-189-2	52793-11-0	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide	202-182-9	92-72-8	2018	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide	205-207-1	135-63-7	-	View substance registered dossier
Ferro Performance Pigments Belgium N.V.	Kortrijkstraat 153 8930 Menen Belgium	Belgium	Active	5'-chloro-3-hydroxy-2'-methyl-2-naphthanilide	205-207-1	135-63-7	-	View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U.	Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain	Spain	Active	5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one monohydrochloride	812-545-9	93173-05-8	-	View substance registered dossier
KINSY, S.L.	Avda. Europa s/n Parque Industrial de Alhama 30840 Alhama de Murcia Murcia Spain	Spain	Active	5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one	212-944-2	885-70-1	-	View substance registered dossier
[Confidential]	-	-	-	5,5'-((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-2-((S)-pyrrolidin-2-yl)-1H-benzo[d]imidazole)	826-675-9	1332357-14-8	-	View substance registered dossier
Fujifilm Imaging Colorants Limited	Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom	United Kingdom	No longer Valid	5,5'-(Ethane-1,2-diylbis(sulfanediyl))bis(1,3,4-thiadiazol-2-amine)	941-658-7	82875-12-5	2021	View substance registered dossier
[Confidential]	-	-	-	5,5'-dimethoxy-3,3'-di-tert.-butyl-1,1'-biphenyl-2,2'-diol	604-200-4	14078-41-2	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	5,5,5',5'-Tetramethyl-2,2'-bi(1,3,2-dioxaborinane)	639-407-9	201733-56-4	2015	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	5,5,5',5'-Tetramethyl-2,2'-bi(1,3,2-dioxaborinane)	639-407-9	201733-56-4	2022	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	5,5,5',5'-Tetramethyl-2,2'-bi(1,3,2-dioxaborinane)	639-407-9	201733-56-4	2022	View substance registered dossier
Robinson Brothers Ltd	Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom	United Kingdom	No longer Valid	5,5-DIMETHYL-2-ISOPROPYLTHIAZOLIDINE	603-850-6	134695-88-8	2021	View substance registered dossier
Robinson Brothers Ltd	Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom	United Kingdom	No longer Valid	5,5-dimethyl-2-propan-2-yl-2H-1,3-thiazole	608-796-7	32899-85-7	2021	View substance registered dossier
Chemische Fabrik Berg GmbH	Mainthalstrasse 3 06749 Bitterfeld-Wolfen Germany	Germany	Active	5,5-dimethylcyclohexane-1,3-dione	204-804-4	126-81-8	2012	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	5,5-dimethylcyclohexane-1,3-dione	204-804-4	126-81-8	-	View substance registered dossier
BENECHIM	René Magritte 163 7860 Lessines Belgium	Belgium	Active	5,5-dimethylcyclohexane-1,3-dione	204-804-4	126-81-8	2012	View substance registered dossier
Chemical Inspection & Regulation Service Limited (Hangzhou Grascent Co., Ltd.)	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	5,5-dimethylcyclohexane-1,3-dione	204-804-4	126-81-8	-	View substance registered dossier
Akema s.r.l.	Via Puglie 12 47853 Coriano RN Italy	Italy	Active	5,5-dimethylhydantoin	201-051-3	77-71-4	-	View substance registered dossier
JSC "Olainfarm"	Rupnicu str. 5 LV-2114 Olaine Latvia	Latvia	Active	5,5-pentamethylene-7-oxo-2,3,4,5,6,7-hexahydrocyclopenta[a] pyrimidine	922-971-8	-	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	5,6 beta-Epoxy-7 beta-hydroxy-15 beta,16 beta-methylene-3 beta-pivaloyloxy-5 beta-androstan-17-one	617-351-6	82544-13-6	2019	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	5,6 beta-Epoxy-7 beta-hydroxy-15 beta,16 beta-methylene-3 beta-pivaloyloxy-5 beta-androstan-17-one	617-351-6	82544-13-6	2012; 2020; 2022	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	5,6,7,8-tetrahydroquinoline	234-030-2	10500-57-9	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	5,6-Dichloro-pyrimidin-4-ylamine	815-619-9	310400-38-5	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	No longer Valid	5,6-diethylindan-2-aminium chloride	455-940-8	-	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	5,6-diethylindan-2-aminium chloride	455-940-8	-	2022	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Active	5,6-diethylindan-2-aminium chloride	455-940-8	-	2015	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	5,6-Dihydro-2-[trans,trans-4'-propyl(1,1'-bicyclohexyl-4-yl)-4H-1,3-dithiin-1-iumtrifluoromethanesulfonate	609-186-3	358732-12-4	2022	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1h,4h)-dione	695-944-9	92260-81-6	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	5,6-dimethoxyindoline	927-137-7	15937-07-2	-	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	5,6-dimethylbenzimidazole	209-488-1	582-60-5	2021; 2022	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	2020	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	5,7,12,14-tetrahydro-7,14-dioxo-quino[2,3-b]acridine-2,9-disulfonyl dichloride	610-420-1	483965-67-9	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	5,7-diazaspiro[3.4]octane-6,8-dione	618-291-3	89691-88-3	-	View substance registered dossier
Corteva Agriscience France S.A.S.	Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France	France	Cease Manufacture	5,7-dichloro-4-hydroxyquinoline-3-carboxylic acid	431-250-2	171850-30-9	2022	View substance registered dossier
Corteva Agriscience UK Limited	CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom	United Kingdom	No longer Valid	5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-amine	603-562-0	13223-43-3	2021	View substance registered dossier
GE Healthcare AS	Nycoveien 1 Postboks 4220 Nydalen 0401 Oslo Oslo Norway	Norway	Active	5,8-bis(carboxymethyl)]-11-[2-(methylamino)-2-oxoethyl]-3-oxo-2,5,8,11-tetreazatridecan-13-oic acid	601-640-9	119895-95-3	-	View substance registered dossier
S.I.M.S. S.r.l.	Località Filarone 50066 Reggello (FI) Italy	Italy	Active	5,8-dihydro-1-naphthol	248-596-3	27673-48-9	2019	View substance registered dossier
Prosyntis S.A.S.	10 Allée des Champs-Elysées 91042 Evry cedex France	France	Active	5,8-dihydro-1-naphthol	248-596-3	27673-48-9	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	5,8-Dihydro-1-naphthyl acetate	610-759-5	51927-56-1	-	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	5-(1-Hydroxy-2-{[1-(4-hydroxyphenyl)-2-propanyl]amino}ethyl)-1,3-benzenediol	680-817-2	13392-18-2	2018	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	5-(1-methyl-4-piperidyl)-5H-dibenzo[a,d]cyclohepten-5-ol hydrochloride	223-746-0	4046-24-6	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	5-(1-methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol	609-737-8	3967-32-6	2017	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	5-(1H-1,2,4-Triazol-1ylmethyl)-1H-indole-3-ethanol	620-292-9	160194-39-8	2020	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole	845-721-9	1443623-92-4	-	View substance registered dossier
LusoChimica S.p.A.	Via Giotto, 9 23871 Lomagna (Lecco) Italy	Italy	Active	5-(2-bromoacetyl)-1,3-phenylene diacetate	253-193-0	36763-39-0	2016	View substance registered dossier
PCAS Finland Oy	Messukentänkatu 8 20210 TURKU Finland	Finland	Active	5-(2-chloroethyl)-4-methyl-1,3-thiazole hydrochloride (1:1)	611-928-6	6001-74-7	-	View substance registered dossier
MCM Pharma GmbH	Kleine Johannisstr.10 20457 Hamburg Germany	Germany	Active	5-(2-chloroethyl)-4-methyl-1,3-thiazole hydrochloride (1:1)	611-928-6	6001-74-7	-	View substance registered dossier
[Confidential]	-	-	-	5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione	855-578-4	1150560-59-0	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde	807-719-6	881677-11-8	2015	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde	807-719-6	881677-11-8	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde	809-913-6	881674-56-2	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde	809-913-6	881674-56-2	2022	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile	809-912-0	1240948-77-9	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile	809-912-0	1240948-77-9	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	5-(3-Bromophenyl)pentanoic Acid	878-736-4	857480-35-4	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	5-(3-chlorophenyl)-2-(2-methoxy-2-oxoethylcarbamoyl)pyrid-3-yl pivalate	947-757-1	-	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	5-(3-chlorophenyl)-3-hydroxypicolinic acid	825-120-8	1415226-40-2	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	5-(3-chlorophenyl)-3-methoxypicolinonitrile	815-168-8	1415226-39-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol	214-594-6	1159-03-1	2017	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	2010; 2012	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Cease Manufacture	5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	2010	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	5-(4'-(bromomethyl)biphenyl-2-yl)-1-trityl-1H-tetrazole	603-010-9	124750-51-2	2011	View substance registered dossier
[Confidential]	-	-	-	5-(4-Brom-2-fluorphenylamino)-4-fluor-N-[2-(1,1-dimethylethoxy)ethoxy]-1-methyl-1H-benzo[d]imidazol-6-carboxamid	815-317-7	1604812-70-5	-	View substance registered dossier
[Confidential]	-	-	-	5-(4-bromo-2-fluoroanilino)-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid	815-319-8	1415564-99-6	-	View substance registered dossier
[Confidential]	-	-	-	5-(4-bromo-2-fluoroanilino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide	639-995-7	606143-89-9	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	5-(4-Bromophenyl)-4,6-dichloropyrimidine	807-547-1	146533-41-7	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	5-(4-Bromophenyl)-4,6-dihydroxpyrimidine	814-997-2	706811-25-8	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole	616-036-0	73963-42-5	-	View substance registered dossier
URQUIMA S.A.	AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain	Spain	Active	5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole	616-036-0	73963-42-5	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole	616-036-0	73963-42-5	2017; 2021	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	5-(4-chlorobutyl)-1-cyclohexyl-1H-tetrazole hydrochloride (1:1)	944-938-7	-	-	View substance registered dossier
cordenpharma chenove	47, rue de Longvic 21300 Chenôve France	France	Active	5-(4-Hydroxymethyl-phenoxymethyl)-3-isopropyloxazolidin-2-one	926-787-9	-	-	View substance registered dossier
Deretil S.A.U.	Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain	Spain	Active	5-(4-hydroxyphenyl)imidazolidine-2,4-dione	219-340-8	2420-17-9	-	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	5-(aminosulphonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide monohydrochloride	245-826-4	23694-14-6	-	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Active	5-(bromoacetyl)-1,3-phenylene bis(dimethylcarbamate)	279-805-6	81732-49-2	-	View substance registered dossier
Cosma S.p.A.	Via Colleoni 15/17 24040 Ciserano (BG) Italy	Italy	Active	5-(bromoacetyl)salicylamide	277-626-8	73866-23-6	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	5-(bromoacetyl)salicylamide	277-626-8	73866-23-6	-	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	5-(difluoromethoxy)-1H-1,3-benzodiazole-2-thiol; 5-(difluoromethoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione	417-780-7	-	2022	View substance registered dossier
MOEHS CANTABRA	P.I.Requejada Z-23 39313 Polanco Cantabria Spain	Spain	Active	5-(difluoromethoxy)-1H-1,3-benzodiazole-2-thiol; 5-(difluoromethoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione	417-780-7	-	2022	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	5-(difluoromethoxy)-1H-1,3-benzodiazole-2-thiol; 5-(difluoromethoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione	417-780-7	-	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole	619-308-7	97963-62-7	2018	View substance registered dossier
LAVOLLEE SA	9 rue Louis Rouquier 92300 Levallois Perret France	France	Active	5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole	619-308-7	97963-62-7	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	5-(dimethylamino)-2-nitrobenzoic acid	814-136-0	62876-66-8	-	View substance registered dossier
Purac Bioquímica S.A.U.	Gran Vial 19-25 08160 Montmeló (Barcelona) Spain	Spain	Cease Manufacture	5-(hydroxymethyl)-2-furaldehyde	200-654-9	67-47-0	2023	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	5-(Hydroxymethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	838-943-2	1182358-83-3	-	View substance registered dossier
Avantium Renewable Polymers B.V.	Zekeringstraat 29 1014 BV Amsterdam Netherlands	Netherlands	Active	5-(methoxymethyl)-2-furaldehyde	700-511-5	1917-64-2	-	View substance registered dossier
[Confidential]	-	-	-	5-(methoxymethyl)pyridine-2,3-dicarboxylic acid	604-349-5	143382-03-0	-	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Cease Manufacture	5-(Methylsulfonyl)pyridine-2-carbonitrile	682-451-9	848141-13-9	2022	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	5-(Methylsulfonyl)pyridine-2-carbonitrile	682-451-9	848141-13-9	2022	View substance registered dossier
Givaudan Iberica SA	Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain	Spain	Active	5-(tert-butyl)oct-3-yne-2,5-diol	617-873-4	865205-28-3	-	View substance registered dossier
ZaCh System	ZI La Croix Cadeaux 49242 Avrillè France	France	Active	5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione	601-029-7	111025-46-8	-	View substance registered dossier
LusoChimica S.p.A.	Via Giotto, 9 23871 Lomagna (Lecco) Italy	Italy	Active	5-[(1E)-2-bromoethenyl]-2'-deoxy-, 3',5'-bis(4-chlorobenzoate) uridine	618-029-8	87531-10-0	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	5-[(4-amino-1-naphthyl)azo]-2-anilinobenzenesulphonic acid	259-124-0	54363-79-0	-	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	5-[(4-ethylpiperazin-1-yl)methyl]pyridine-2-amine	806-688-6	1180132-17-5	2017; 2019	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	5-[(p-aminophenyl)azo]salicylic acid	202-948-2	101-51-9	-	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one	928-541-6	146939-27-7	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one	928-541-6	146939-27-7	-	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one; camphorsulphonic acid	806-795-8	909419-73-4	-	View substance registered dossier
Synthon, s.r.o.	Brněnská 32 678 01 Blansko Czech Republic	Czech Republic	Active	5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide	926-076-3	-	-	View substance registered dossier
POLPHARMA	19 Pelplińska 83-200 Starogard Gdański Poland	Poland	Active	5-[2-ethoxy-5-(4-methylpiperazin-1-ylsulphonyl)-phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-on	604-158-7	139755-83-2	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	5-[3-(1-ethoxyethoxy)-3-methyl-4-penten-1-ynyl]-2,4,6,6-tetramethyl-5,6,7,7a-tetrahydro-1,3-benzodioxol-5-ol	605-301-6	162691-59-0	2016	View substance registered dossier

Showing 17,201 - 17,300 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.