Registered substances

Registered substances

Registered substances

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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated
953-553-3 - Active Full Individual ≥ 1 to < 10 tonnes 30-09-2021 View substance registered dossier
oxalic acid-4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (1/1)
953-548-6 - Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one
953-513-5 - Active Full Joint ≥ 0 to < 10 tonnes 04-08-2021 View substance registered dossier
Reaction mass of 3-({1-[(1-methoxypropan-2-yl)oxy]propan-2-yl}oxy)prop-1-ene and 3-{[1-(2-methoxypropoxy)propan-2-yl]oxy}prop-1-ene
953-504-6 - Active Intermediate Individual Intermediate use only 26-03-2021 View substance registered dossier
Cerium gadolinium oxide
953-470-2 - Active Full Individual ≥ 1 to < 10 tonnes 03-02-2022 View substance registered dossier
Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
953-451-9 - Active Full Joint ≥ 10 to < 100 tonnes 09-05-2022 View substance registered dossier
Reaction mass of 1-(2-hydroxyphenyl)-ethanone and 1-(3-methyl-2-benzofuranyl)-ethanone
953-441-4 - Active Intermediate Joint Intermediate use only 27-01-2021 View substance registered dossier
Reaction mass of 1,1,1,3,5,5,5-heptamethyltrisiloxane and 1,1,1,3,5,7,7,7-octamethyltetrasiloxane and hexamethyldisiloxane
953-427-8 - Active Intermediate Individual Intermediate use only 11-12-2020 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside
953-425-7 217500-75-9 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
Benzenesulfonic acid, 4-C10-13-alkyl derivs.-, salts with amines, C16-C18 (even numbered) alkyl
953-378-2 - Active Full Joint ≥ 100 to < 1 000 tonnes 11-06-2021 View substance registered dossier
Reaction mass of [(4-hydroxybutyl)imino]dihexane-6,1-diyl bis(2-hexyldecanoate) and 6-oxohexyl 2-hexyldecanoate
953-347-3 - Cease Manufacture Intermediate Individual Cease manufacture 17-11-2020 View substance registered dossier
RICE OLIGOPEPTIDE from controlled enzymatic hydrolysis of rice protein
953-344-7 - Active Full Individual ≥ 1 to < 10 tonnes 20-12-2021 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranosyl-4-ulose)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 2-O-[(benzyloxy)carbonyl]-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside trifluoroacetate (1:2)
953-335-8 1210740-88-7 Active Intermediate Joint Intermediate use only 30-03-2021 View substance registered dossier
6-(2’-hexyldecanoyloxy)hexan-1-al
953-300-7 1849616-54-1 Active Intermediate Joint Intermediate use only 18-05-2022 View substance registered dossier
Extract of fava d'anta, obtained from the fruits of Dimorphandra mollis (Leguminosae) by solvent extraction
953-265-8 - Active Full Joint ≥ 10 to < 100 tonnes 01-10-2021 View substance registered dossier
Rection mass of 1-(benzyl(2-hydroxyethyl)amino)-3-((2-ethylhexyl)oxy)propan-2-ol and 1-(dibenzylamino)-3-((2-ethylhexyl)oxy)propan-2-ol
953-230-7 - Active Intermediate Individual Intermediate use only 11-11-2020 View substance registered dossier
N-[(4-{5-AMINO-4-CYANO-1-[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]-1H-PYRAZOL-3-YL}PHENYL)METHYL]-5-FLUORO-2-METHOXYBENZAMIDE
953-182-7 - Active Intermediate Individual Intermediate use only 07-01-2021 View substance registered dossier
monoesters of C16 and C18 (branched and linear) fatty acids with decan-1-ol
953-178-5 - Active Full Joint ≥ 100 to < 1 000 tonnes 14-10-2021 View substance registered dossier
{(3aR,4R,6R,6aR)-6-[(4Z)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin1(2H)-yl]-2,2-dimethyltetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl}methyl2methylpropanoate
953-132-4 2346620-55-9 Active Intermediate Joint Intermediate use only 15-12-2020 View substance registered dossier
Reaction mass of Disodium [3-{[4-chloro-2-(hydroxy-kO)-5-methoxyphenyl]diazenyl-kN2}-4-(hydroxy-kO)naphthalene-2,7-disulfonato(4-)](hydroxy)chromate(2-) and Trisodium [3-{[4-chloro-2-(hydroxy-kO)-5-methoxyphenyl]diazenyl-kN2}-4-(hydroxy-kO)naphthalene-2,7-disulfonato(4-)](dihydroxy)chromate(3-)
953-115-1 - Active Full Joint ≥ 1 to < 10 tonnes 24-06-2021 View substance registered dossier
Reaction mass of oxybispropanediol and tetraglycerol and triglycerol, esterification products with lactic acid and lauric acid
953-104-1 - Active Full Joint ≥ 1 to < 10 tonnes 17-12-2021 View substance registered dossier
N'-[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]BENZOHYDRAZIDE
953-102-0 - Active Intermediate Individual Intermediate use only 18-02-2021 View substance registered dossier
N-{[4-(2,2-DICYANO-1-HYDROXYETHENYL)PHENYL]METHYL}-5-FLUORO-2-METHOXYBENZAMIDE
953-101-5 - Active Intermediate Individual Intermediate use only 21-12-2020 View substance registered dossier
6-(2’-hexyldecanoyloxy)hexan-1-ol
953-086-5 1849616-53-0 Active Intermediate Joint Intermediate use only 18-05-2022 View substance registered dossier
Reaction Mass of Valencene and Aristolochene
953-082-3 - Active Intermediate Individual Intermediate use only 21-05-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ICC Industries, B.V. Hullenbergweg 278 1101 BV Amsterdam The Netherlands Netherlands Netherlands Active Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated 953-553-3 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active oxalic acid-4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (1/1) 953-548-6 - - View substance registered dossier
Yordas GmbH Äuβere Nürnberger Straβe 62 91301 Forchheim Germany Germany Active ((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one 953-513-5 - - View substance registered dossier
Dow Silicones Belgium SPRL OR-1 rue Jules Bordet Parc industriel C 7180 Seneffe Belgium Belgium Active Reaction mass of 3-({1-[(1-methoxypropan-2-yl)oxy]propan-2-yl}oxy)prop-1-ene and 3-{[1-(2-methoxypropoxy)propan-2-yl]oxy}prop-1-ene 953-504-6 - 2020; 2021 View substance registered dossier
RHODIA OPERATIONS 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France France Active Cerium gadolinium oxide 953-470-2 - - View substance registered dossier
seppic sa 50 boulevard National CS 90020 92257 La Garenne Colombes ile de france France France Active Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate 953-451-9 - 2022 View substance registered dossier
Intertek Italia SpA_IFB Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO, Milano Italy Italy Active Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate 953-451-9 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of 1-(2-hydroxyphenyl)-ethanone and 1-(3-methyl-2-benzofuranyl)-ethanone 953-441-4 - - View substance registered dossier
[Confidential] - - - Reaction mass of 1,1,1,3,5,5,5-heptamethyltrisiloxane and 1,1,1,3,5,7,7,7-octamethyltetrasiloxane and hexamethyldisiloxane 953-427-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside 953-425-7 217500-75-9 - View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active Benzenesulfonic acid, 4-C10-13-alkyl derivs.-, salts with amines, C16-C18 (even numbered) alkyl 953-378-2 - 2021 View substance registered dossier
Asfaltos del Sureste, S.A Calle Pachecas De Abajo, 1 30740 Murcia San Pedro del Pinatar Spain Spain Active Benzenesulfonic acid, 4-C10-13-alkyl derivs.-, salts with amines, C16-C18 (even numbered) alkyl 953-378-2 - - View substance registered dossier
Croda EU B.V. (OR8) Buurtje 1 2802 BE Gouda Netherlands Netherlands Cease Manufacture Reaction mass of [(4-hydroxybutyl)imino]dihexane-6,1-diyl bis(2-hexyldecanoate) and 6-oxohexyl 2-hexyldecanoate 953-347-3 - 2022 View substance registered dossier
Vevy Europe SpA Via Semeria 16a 16131 Genova Italy Italy Active RICE OLIGOPEPTIDE from controlled enzymatic hydrolysis of rice protein 953-344-7 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranosyl-4-ulose)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 2-O-[(benzyloxy)carbonyl]-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside trifluoroacetate (1:2) 953-335-8 1210740-88-7 2021 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 6-(2’-hexyldecanoyloxy)hexan-1-al 953-300-7 1849616-54-1 - View substance registered dossier
Croda EU B.V. (OR8) Buurtje 1 2802 BE Gouda Netherlands Netherlands Cease Manufacture 6-(2’-hexyldecanoyloxy)hexan-1-al 953-300-7 1849616-54-1 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 6-(2’-hexyldecanoyloxy)hexan-1-al 953-300-7 1849616-54-1 2022 View substance registered dossier
[Confidential] - - - Extract of fava d'anta, obtained from the fruits of Dimorphandra mollis (Leguminosae) by solvent extraction 953-265-8 - - View substance registered dossier
DOW BENELUX B.V. OR-10 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active Rection mass of 1-(benzyl(2-hydroxyethyl)amino)-3-((2-ethylhexyl)oxy)propan-2-ol and 1-(dibenzylamino)-3-((2-ethylhexyl)oxy)propan-2-ol 953-230-7 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active N-[(4-{5-AMINO-4-CYANO-1-[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]-1H-PYRAZOL-3-YL}PHENYL)METHYL]-5-FLUORO-2-METHOXYBENZAMIDE 953-182-7 - - View substance registered dossier
Croda Nederland BV Buurtje 1 2802 BE Gouda Netherlands Netherlands Active monoesters of C16 and C18 (branched and linear) fatty acids with decan-1-ol 953-178-5 - - View substance registered dossier
Croda Iberica SA Mevisa Site Carretera C-35 Km 72 (Hostalric-Blanes) 08495 Fogars de la Selva Barcelona Spain Spain Active monoesters of C16 and C18 (branched and linear) fatty acids with decan-1-ol 953-178-5 - 2019; 2021 View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active {(3aR,4R,6R,6aR)-6-[(4Z)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin1(2H)-yl]-2,2-dimethyltetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl}methyl2methylpropanoate 953-132-4 2346620-55-9 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active {(3aR,4R,6R,6aR)-6-[(4Z)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin1(2H)-yl]-2,2-dimethyltetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl}methyl2methylpropanoate 953-132-4 2346620-55-9 - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active Reaction mass of Disodium [3-{[4-chloro-2-(hydroxy-kO)-5-methoxyphenyl]diazenyl-kN2}-4-(hydroxy-kO)naphthalene-2,7-disulfonato(4-)](hydroxy)chromate(2-) and Trisodium [3-{[4-chloro-2-(hydroxy-kO)-5-methoxyphenyl]diazenyl-kN2}-4-(hydroxy-kO)naphthalene-2,7-disulfonato(4-)](dihydroxy)chromate(3-) 953-115-1 - - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 034 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active Reaction mass of oxybispropanediol and tetraglycerol and triglycerol, esterification products with lactic acid and lauric acid 953-104-1 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active N'-[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]BENZOHYDRAZIDE 953-102-0 - 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active N-{[4-(2,2-DICYANO-1-HYDROXYETHENYL)PHENYL]METHYL}-5-FLUORO-2-METHOXYBENZAMIDE 953-101-5 - 2020 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 6-(2’-hexyldecanoyloxy)hexan-1-ol 953-086-5 1849616-53-0 2022 View substance registered dossier
Croda EU B.V. (OR8) Tribes Utrecht Centraal Station Leidseveer 2-10 3511 SB Utrecht Netherlands Netherlands Cease Manufacture 6-(2’-hexyldecanoyloxy)hexan-1-ol 953-086-5 1849616-53-0 2022 View substance registered dossier
ADL Biopharma S.L.U Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active Reaction Mass of Valencene and Aristolochene 953-082-3 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

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In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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