Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 19,101 - 19,200 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
4-(Cyclopropylcarbonyl)-α,α-dimethyl-ethyl ester benzeneacetic acid	605-546-9	169280-10-8	Active	Intermediate	Joint	Intermediate use only	14-02-2022	View substance registered dossier
4-(cyclohexylcarbonoimidoyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol	940-185-3	32860-09-6	Active	Intermediate	Individual	Intermediate use only	10-01-2014	View substance registered dossier
4-(cyclohexylamino)butane-1-sulfonic acid	629-080-0	161308-34-5	Active	Full	Joint	≥ 1 to < 10 tonnes	08-12-2022	View substance registered dossier
4-(cyclohex-1-en-1-yl)-3-methylbutan-1-ol	806-826-5	1359994-45-8	Active	Full	Joint	≥ 1 to < 10 tonnes	12-10-2022	View substance registered dossier
4-(chloromethyl)benzoyl chloride	212-881-0	876-08-4	Active	Intermediate	Joint	Intermediate use only	18-03-2022	View substance registered dossier
4-(chlorodimethylsilyl)butyronitrile	242-039-8	18156-15-5	Active	Intermediate	Joint	Intermediate use only	15-02-2018	View substance registered dossier
4-(chlorocarbonyl)phenyl 3-chloropropanoate	609-280-4	366448-53-5	Active	Intermediate	Joint	Intermediate use only	30-10-2020	View substance registered dossier
4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	Active	Full	Joint	≥ 10 to < 100 tonnes	08-03-2023	View substance registered dossier
4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	Active	Full	Individual	≥ 1 to < 10 tonnes	18-06-2015	View substance registered dossier
4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	No longer Valid	NONS	Individual	No longer valid	08-01-2014	View substance registered dossier
4-(bromoacetyl)-1,3-phenylene dimethyl biscarbonate	807-596-9	1428451-07-3	Active	Intermediate	Joint	Intermediate use only	15-03-2022	View substance registered dossier
4-(benzyloxy)-α-[[tert-butylamino]methyl]-m-xylene-α,α'-diol	260-385-8	56796-66-8	Active	Intermediate	Joint	Intermediate use only	22-08-2019	View substance registered dossier
4-(benzylamino)-5-methyl-2(1H)-pyridinon	809-933-5	95306-62-0	Active	Intermediate	Individual	Intermediate use only	21-08-2018	View substance registered dossier
4-(benzoylamino)-6-[[5-[[(5-chloro-2,6-difluoro-4-pyrimidinyl)amino]methyl]-1-sulpho-2-naphthyl]azo]-5-hydroxynaphthalene-1,7-disulphonic acid, lithium sodium salt	280-426-3	83400-11-7	Active	Full	Joint	≥ 1 to < 10 tonnes	06-04-2018	View substance registered dossier
4-(aminomethyl)octane-1,8-diamine	216-392-3	1572-55-0	Active	Full	Joint	≥ 1 to < 10 tonnes	08-10-2022	View substance registered dossier
4-(aminomethyl)-1-phenethylpiperidin-4-ol dihydrochloride	245-892-4	23804-64-0	Active	Intermediate	Joint	Intermediate use only	23-07-2020	View substance registered dossier
4-([1,2,4]triazolo[1,5-a]pyrid-7-yloxy)-3-methylaniline	856-352-8	937263-71-3	Active	Intermediate	Joint	Intermediate use only	16-07-2020	View substance registered dossier
4-(6-methylbenzothiazol-2-yl)aniline	202-150-4	92-36-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	27-11-2012	View substance registered dossier
4-(6-HYDROXYHEXYLOXY)BENZOIC ACID	617-498-6	83883-25-4	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)	425-880-7	-	Active	Full	Joint	≥ 1 to < 10 tonnes	21-05-2019	View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)	425-880-7	-	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)	425-120-4	83847-14-7	Active	Full	Joint	≥ 1 to < 10 tonnes	17-09-2018	View substance registered dossier
4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)	425-120-4	83847-14-7	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(6-(methylsulfonyloxy)benzo[b]thiophen-2-yl)phenyl methanesulfonate	806-588-2	84449-65-0	Active	Intermediate	Joint	Intermediate use only	08-06-2016	View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate	951-814-6	-	Active	Intermediate	Individual	Intermediate use only	03-01-2020	View substance registered dossier
4-(5-Sulfanyl-1H-tetrazol-1-yl)benzoic acid	680-188-4	23249-95-8	Active	Intermediate	Individual	Intermediate use only	12-12-2014	View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol	919-949-5	-	Active	Full	Joint	≥ 0 to < 10 tonnes	17-12-2021	View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide VALDECOXIB	448-010-8	-	Active	Intermediate	Joint	Intermediate use only	20-08-2018	View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide VALDECOXIB	448-010-8	-	Active	NONS	Individual	Tonnage data confidential	15-12-2008	View substance registered dossier
4-(5-Ethyl-tetrahydropyran-2-yl)-phenol	921-114-5	-	Active	Full	Joint	≥ 0 to < 10 tonnes	23-10-2020	View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one ETHOCYN	419-880-6	-	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt	426-900-7	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide	954-921-6	-	Active	Full	Joint	≥ 0 to < 10 tonnes	04-04-2023	View substance registered dossier
4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol	266-100-3	66068-84-6	Active	Full	Joint	≥ 100 to < 1 000 tonnes	05-01-2019	View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene	430-860-6	-	Active	NONS	Individual	Tonnage data confidential	05-11-2019	View substance registered dossier
4-(4-trans-propylcylohexyl)phenol PCH-3-PHENOL	440-740-5	-	Active	Intermediate	Joint	Intermediate use only	20-12-2019	View substance registered dossier
4-(4-tolyloxy)biphenyl JKY-120	405-730-7	51601-57-1	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(4-pyridyl)-3H-thiazole-2-thione	616-441-2	77168-63-9	No longer Valid	Intermediate	Individual	No longer valid	11-03-2011	View substance registered dossier
4-(4-pyridyl)-3H-thiazole-2-thione	616-441-2	77168-63-9	Active	Intermediate	Joint	Intermediate use only	08-06-2021	View substance registered dossier
4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol MORTRACE SB CONC.	410-610-2	111850-24-9	Active	Full	Joint	≥ 10 to < 100 tonnes	08-02-2023	View substance registered dossier
4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol MORTRACE SB CONC.	410-610-2	111850-24-9	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
4-(4-nitrophenyl)sulfonylaniline	606-323-9	1948-92-1	Active	Intermediate	Individual	Intermediate use only	17-10-2016	View substance registered dossier
4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	Active	Intermediate	Joint	Intermediate use only	04-08-2020	View substance registered dossier
4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester	840-712-6	1034975-53-5	Active	Intermediate	Individual	Intermediate use only	26-06-2019	View substance registered dossier
4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	Active	Full	Joint	≥ 100 to < 1 000 tonnes	14-04-2022	View substance registered dossier
4-(4-methylbenzenesulfonyl)benzene-1,2-diol	695-163-3	107065-85-0	Active	Full	Joint	≥ 10 to < 100 tonnes	12-08-2020	View substance registered dossier
4-(4-methoxyphenyl)cyclohexanone	610-959-2	5309-16-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	23-05-2014	View substance registered dossier
4-(4-methoxyphenyl)butyric acid	224-849-3	4521-28-2	Active	Intermediate	Joint	Intermediate use only	31-10-2017	View substance registered dossier
4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	Active	Full	Joint	≥ 10 to < 100 tonnes	23-03-2020	View substance registered dossier
4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	Active	Intermediate	Individual	Intermediate use only	05-12-2016	View substance registered dossier
4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	Active	Intermediate	Joint	Intermediate use only	27-02-2017	View substance registered dossier
4-(4-methoxyphenyl)-3-buten-2-one	213-404-9	943-88-4	Active	Intermediate	Joint	Intermediate use only	23-05-2018	View substance registered dossier
4-(4-isopropoxyphenylsulfonyl)phenol D-8; DD-8	405-520-5	95235-30-6	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
4-(4-isopropoxyphenylsulfonyl)phenol D-8; DD-8	405-520-5	95235-30-6	Active	Full	Joint	≥ 100 tonnes	13-11-2020	View substance registered dossier
4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	Active	Intermediate	Joint	Intermediate use only	11-03-2020	View substance registered dossier
4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	Active	Intermediate	Individual	Intermediate use only	18-11-2011	View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone 4-(4'-HYDROXYPHENYL)-CYCLOHEXANON	423-920-8	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	Active	Full	Joint	≥ 100 to < 1 000 tonnes	17-05-2018	View substance registered dossier
4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	Active	Intermediate	Joint	Intermediate use only	12-02-2019	View substance registered dossier
4-(4-hydroxybenzenesulfonyl)phenol bis(tetraphenylphosphanium) bis(4-(4-hydroxybenzenesulfonyl)benzen-1-olate)	484-440-2	502157-74-6	Active	Full	Joint	≥ 1 tonnes	24-04-2023	View substance registered dossier
4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide	425-850-3	125971-96-2	Active	Intermediate	Joint	Intermediate use only	19-11-2021	View substance registered dossier
4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide	425-850-3	125971-96-2	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(4-cyclopropyl-1-naphthyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione	943-285-5	1533519-84-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	27-04-2016	View substance registered dossier
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid	810-200-7	1050477-45-6	Active	Intermediate	Individual	Intermediate use only	22-02-2023	View substance registered dossier
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide	810-201-2	1050477-27-4	Active	Intermediate	Individual	Intermediate use only	22-02-2023	View substance registered dossier
4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione	258-858-9	53911-68-5	Active	Intermediate	Joint	Intermediate use only	21-11-2017	View substance registered dossier
4-(4-chlorophenyl)-3-methyl-4-oxo-butanoic acid	610-810-1	52240-25-2	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile INDAR	406-140-2	114369-43-6	Active	Full	Joint	≥ 1 to < 10 tonnes	07-09-2021	View substance registered dossier
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile INDAR	406-140-2	114369-43-6	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol	925-590-5	-	Active	Intermediate	Joint	Intermediate use only	16-01-2017	View substance registered dossier
4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid	918-019-6	-	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
4-(4-chloro-1,2,5-thiadiazol-3-yl)morpholine	250-077-1	30165-96-9	Active	Intermediate	Joint	Intermediate use only	19-12-2022	View substance registered dossier
4-(4-bromo-3-formylphenoxy)benzonitrile	822-547-1	906673-54-9	Active	Intermediate	Joint	Intermediate use only	23-07-2019	View substance registered dossier
4-(4-bromo-3-((tetrahydro-2H-pyran-2-yloxy)methyl)phenoxy)benzonitrile	807-693-6	943311-78-2	Active	Intermediate	Joint	Intermediate use only	18-03-2015	View substance registered dossier
4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol	917-991-9	-	Active	Intermediate	Joint	Intermediate use only	16-02-2018	View substance registered dossier
4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol	919-822-4	-	Active	Intermediate	Joint	Intermediate use only	25-05-2018	View substance registered dossier
4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	Cease Manufacture	Intermediate	Individual	Cease manufacture	06-02-2013	View substance registered dossier
4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide	608-211-5	284462-37-9	Active	Full	Individual	≥ 1 to < 10 tonnes	12-11-2021	View substance registered dossier
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide	692-721-8	757251-39-1	Active	Intermediate	Individual	Intermediate use only	02-12-2014	View substance registered dossier
4-(4-Allyloxy-benzenesulfonyl)-phenol	479-880-7	97042-18-7	Active	Full	Joint	≥ 100 tonnes	11-05-2020	View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid	462-560-6	-	No longer Valid	Intermediate	Individual	No longer valid	10-05-2011	View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid	462-560-6	-	Active	Intermediate	Joint	Intermediate use only	06-07-2015	View substance registered dossier
4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride TRIAZIMOCH	447-230-1	3945-69-5	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole	485-420-6	182918-16-7	Active	Full	Joint	≥ 10 to < 100 tonnes	16-05-2012	View substance registered dossier
4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole	485-420-6	182918-16-7	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
4-(4,4-dimethyl-3-oxo-pyrazolidin-1-yl)-benzoic acid CARBODIM	413-120-7	107144-30-9	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol	627-688-0	269409-70-3	Active	Intermediate	Joint	Intermediate use only	29-07-2022	View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde	473-430-3	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
4-(3-triethoxysilylpropoxy)-2-hydroxybenzophenone	431-490-8	79876-59-8	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
4-(3-phenylpropyl)pyridine	218-159-1	2057-49-0	Active	Full	Joint	≥ 10 to < 100 tonnes	30-05-2018	View substance registered dossier
4-(3-methylbut-2-enyl)phenol	686-822-6	1200-09-5	Active	Intermediate	Individual	Intermediate use only	10-11-2015	View substance registered dossier
4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	Active	Full	Individual	≥ 1 to < 10 tonnes	19-02-2015	View substance registered dossier
4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	Active	Intermediate	Joint	Intermediate use only	22-05-2018	View substance registered dossier
4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ol	839-457-3	1269440-57-4	Active	Intermediate	Joint	Intermediate use only	28-05-2020	View substance registered dossier
4-(3-hydroxypropylamino)-1,3-dimethyluracil	252-128-3	34654-80-3	Active	Intermediate	Joint	Intermediate use only	23-01-2018	View substance registered dossier
4-(3-hydroxypropoxy)benzoic acid	918-767-3	46350-87-2	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile	948-544-6	2141947-89-7	Active	Intermediate	Joint	Intermediate use only	22-08-2019	View substance registered dossier
4-(3-Fluorbenzyloxy)benzaldehyde	613-982-6	66742-57-2	Active	Intermediate	Joint	Intermediate use only	17-12-2019	View substance registered dossier
4-(3-chloropropyl)morpholine	461-510-0	7357-67-7	Active	NONS	Joint	Tonnage data confidential	05-06-2019	View substance registered dossier
4-(3-Butenyl)-4''-ethyl-2'-fluor-1,1':4',1''-terphenyl	619-966-5	825633-86-1	Active	Full	Joint	≥ 0 to < 10 tonnes	24-06-2022	View substance registered dossier

Showing 19,101 - 19,200 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	4-(Cyclopropylcarbonyl)-α,α-dimethyl-ethyl ester benzeneacetic acid	605-546-9	169280-10-8	2022	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	4-(cyclohexylcarbonoimidoyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol	940-185-3	32860-09-6	-	View substance registered dossier
BorsodChem Zrt. - OR	Bolyai ter 1. H-3700 Kazincbarcika Hungary	Hungary	Active	4-(cyclohexylamino)butane-1-sulfonic acid	629-080-0	161308-34-5	2020; 2022	View substance registered dossier
PFW Aroma Ingredients BV	Veemweg 29-31 3771 MT Barneveld Netherlands	Netherlands	Active	4-(cyclohex-1-en-1-yl)-3-methylbutan-1-ol	806-826-5	1359994-45-8	2021; 2022	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Active	4-(chloromethyl)benzoyl chloride	212-881-0	876-08-4	2022	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	4-(chloromethyl)benzoyl chloride	212-881-0	876-08-4	-	View substance registered dossier
Wacker Chemie AG	Hanns-Seidel-Platz 4 81737 Muenchen Germany	Germany	Active	4-(chlorodimethylsilyl)butyronitrile	242-039-8	18156-15-5	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-(chlorocarbonyl)phenyl 3-chloropropanoate	609-280-4	366448-53-5	-	View substance registered dossier
Chemical Inspection & Regulation Service Limited (Nanjing Huashi New Material Co., Ltd.)	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	-	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	2019	View substance registered dossier
evident ingredients GmbH	Holsteinischer Kamp 95-97 22081 Hamburg Germany	Germany	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	-	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	-	View substance registered dossier
Frey + Lau GmbH	Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany	Germany	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	-	View substance registered dossier
cosphatec GmbH	Hopfenmarkt 33 20457 Hamburg Germany	Germany	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	-	View substance registered dossier
TÜV SÜD Iberia S.A.U. (015)	Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain	Spain	Active	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	2010; 2012; 2015	View substance registered dossier
Takasago UK Ltd	9 High Street SL5 7JF Ascot Berkshire United Kingdom	United Kingdom	No longer Valid	4-(butoxymethyl)-2-methoxyphenol	444-010-7	82654-98-6	2021	View substance registered dossier
Alzchem Trostberg GmbH	Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany	Germany	Active	4-(bromoacetyl)-1,3-phenylene dimethyl biscarbonate	807-596-9	1428451-07-3	2022	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	4-(benzyloxy)-α-[[tert-butylamino]methyl]-m-xylene-α,α'-diol	260-385-8	56796-66-8	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	4-(benzylamino)-5-methyl-2(1H)-pyridinon	809-933-5	95306-62-0	-	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Active	4-(benzoylamino)-6-[[5-[[(5-chloro-2,6-difluoro-4-pyrimidinyl)amino]methyl]-1-sulpho-2-naphthyl]azo]-5-hydroxynaphthalene-1,7-disulphonic acid, lithium sodium salt	280-426-3	83400-11-7	-	View substance registered dossier
REACH24H Consulting Group	Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	4-(aminomethyl)octane-1,8-diamine	216-392-3	1572-55-0	-	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	4-(aminomethyl)-1-phenethylpiperidin-4-ol dihydrochloride	245-892-4	23804-64-0	-	View substance registered dossier
ORIL INDUSTRIE	13 rue Auguste Desgenétais 76210 BOLBEC France	France	Active	4-(aminomethyl)-1-phenethylpiperidin-4-ol dihydrochloride	245-892-4	23804-64-0	2019; 2020	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	4-(aminomethyl)-1-phenethylpiperidin-4-ol dihydrochloride	245-892-4	23804-64-0	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	4-([1,2,4]triazolo[1,5-a]pyrid-7-yloxy)-3-methylaniline	856-352-8	937263-71-3	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Cease Manufacture	4-(6-methylbenzothiazol-2-yl)aniline	202-150-4	92-36-4	2013	View substance registered dossier
SYNTHEXIM	1 Quai d'Amérique 62 100 calais France	France	Active	4-(6-HYDROXYHEXYLOXY)BENZOIC ACID	617-498-6	83883-25-4	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)	425-880-7	-	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)	425-880-7	-	2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	No longer Valid	4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)	425-880-7	-	2022	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)	425-120-4	83847-14-7	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)	425-120-4	83847-14-7	2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)	425-120-4	83847-14-7	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4-(6-(methylsulfonyloxy)benzo[b]thiophen-2-yl)phenyl methanesulfonate	806-588-2	84449-65-0	2016	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate	951-814-6	-	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-(5-Sulfanyl-1H-tetrazol-1-yl)benzoic acid	680-188-4	23249-95-8	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(5-Propyl-tetrahydropyran-2-yl)-phenol	919-949-5	-	2021	View substance registered dossier
Piramal Healthcare UK Ltd	Whalton Road NE61 3YA Morpeth Northumberland United Kingdom	United Kingdom	No longer Valid	4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide	448-010-8	-	2021	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide	448-010-8	-	2016	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide	448-010-8	-	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(5-Ethyl-tetrahydropyran-2-yl)-phenol	921-114-5	-	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	4-(5-ethoxyheptyl)perhydropentalen-2-one	419-880-6	-	2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt	426-900-7	-	-	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa-Attiki Greece	Greece	Active	4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide	954-921-6	-	2023	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa-Attiki Greece	Greece	Active	4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide	954-921-6	-	2021	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol	266-100-3	66068-84-6	-	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol	266-100-3	66068-84-6	2015; 2018; 2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene	430-860-6	-	2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(4-trans-propylcylohexyl)phenol	440-740-5	-	2009; 2010; 2013; 2017; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	4-(4-tolyloxy)biphenyl	405-730-7	51601-57-1	-	View substance registered dossier
Fine and Performance Chemicals Ltd	Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom	United Kingdom	No longer Valid	4-(4-pyridyl)-3H-thiazole-2-thione	616-441-2	77168-63-9	2021	View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd	Długosza 67 43-188 Orzesze Poland	Poland	Active	4-(4-pyridyl)-3H-thiazole-2-thione	616-441-2	77168-63-9	-	View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd	Via Ribes, 5 10010 Colleretto Giacosa TO Italy	Italy	Active	4-(4-pyridyl)-3H-thiazole-2-thione	616-441-2	77168-63-9	-	View substance registered dossier
Chemsafe s.r.l.	Via Ribes 5 10010 Colleretto Giacosa (TO) Italy	Italy	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
DOW BENELUX B.V.	Postbus 48 4530 AA Terneuzen Netherlands	Netherlands	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	2011; 2012; 2016; 2018; 2023	View substance registered dossier
Dow Belgium B.V.B.A.	Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium	Belgium	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
CS Regulatory IRL Ltd 2M-6	Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland	Ireland	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol	410-610-2	111850-24-9	-	View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A	via quarta strada 2 35129 padova Italy	Italy	Active	4-(4-nitrophenyl)sulfonylaniline	606-323-9	1948-92-1	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-Nitrophenyl)-morpholin-3-on	610-199-1	446292-04-2	2012; 2020	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester	840-712-6	1034975-53-5	-	View substance registered dossier
IGM Resins B.V.	Gompenstraat 49 5145 RA Waalwijk Netherlands	Netherlands	Active	4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	2022	View substance registered dossier
Chemical Inspection & Regulation Service Limited	Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	2020	View substance registered dossier
ARKEMA FRANCE	420 rue d'Estienne d'Orves 92700 COLOMBES France	France	Active	4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	2020; 2021	View substance registered dossier
HP Printing and Computing Solutions S.L.	calle de José Echegaray 18 28232 Las Rozas de Madrid (Madrid) Spain	Spain	Active	4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	2018; 2019	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-(4-methylphenylthio)benzophenone	281-064-9	83846-85-9	-	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-(4-methylbenzenesulfonyl)benzene-1,2-diol	695-163-3	107065-85-0	-	View substance registered dossier
Agfa-Gevaert N.V.	Septestraat 27 2640 Mortsel Belgium	Belgium	Active	4-(4-methylbenzenesulfonyl)benzene-1,2-diol	695-163-3	107065-85-0	2016; 2019; 2020	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	4-(4-methoxyphenyl)cyclohexanone	610-959-2	5309-16-0	2018	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Active	4-(4-methoxyphenyl)butyric acid	224-849-3	4521-28-2	-	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	2018; 2019	View substance registered dossier
Symrise Ltd.	Fieldhouse Lane SL7 1TB Marlow Bucks Buckinghamshire United Kingdom	United Kingdom	No longer Valid	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	2021	View substance registered dossier
AROMA RISE S.A.	Industriilor no. 1 601124 ONESTI BACAU Romania	Romania	Active	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	-	View substance registered dossier
NEW INTERNATIONAL SRL	DECEBAL BLVD. 030968 BUCHAREST Romania	Romania	Active	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	-	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	4-(4-methoxyphenyl)butan-2-one	203-184-2	104-20-1	-	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	4-(4-methoxyphenyl)-3-buten-2-one	213-404-9	943-88-4	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	4-(4-methoxyphenyl)-3-buten-2-one	213-404-9	943-88-4	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	-	View substance registered dossier
IVICT Europe GmbH	Kennedydamm 19 40476 Düsseldorf Germany	Germany	Cease Manufacture	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	2020	View substance registered dossier
Nagase (Europa) GmbH	Immermannstraße 65c 40210 Düsseldorf Germany	Germany	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	-	View substance registered dossier
Chameleon Specialty Chemicals B.V.	Kamillelaan 1 3925RG Scherpenzeel Netherlands	Netherlands	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	2020	View substance registered dossier
Intertek Deutschland GmbH	Stangenstr.1 70771 Leinfelden-Echterdingen Baden-Württemberg Germany	Germany	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	-	View substance registered dossier
Nisso Chemical Europe	Berliner Allee 42 40212 Duesseldorf Germany	Germany	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	2020	View substance registered dossier
REACH24H CONSULTING GROUP	Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	-	View substance registered dossier
Sumitomo France SAS	152 Avenue des Champs-Élysées 75008 Paris France	France	Active	4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	2010; 2019; 2020	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	2013	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Cease Manufacture	4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	2021	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	-	View substance registered dossier
Curia France SAS	ZI de Laville 47240 BON-ENCONTRE France	France	Active	4-(4-iodo-1H-pyrazol-1-yl)piperidine	639-824-6	1229457-94-6	-	View substance registered dossier
-	-	-	-	4-(4-hydroxyphenyl)cyclohexanone	423-920-8	-	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	2015	View substance registered dossier
ROLABO OUTSOURCING, S.L.	Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain	Spain	Active	4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	-	View substance registered dossier
Zoetis Belgium S.A.	Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium	Belgium	Active	4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	-	View substance registered dossier
Huvepharma Italia s.r.l.	Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy	Italy	Active	4-(4-hydroxyphenyl)butan-2-one	226-806-4	5471-51-2	-	View substance registered dossier
Vyncolit NV (OR SBJ)	Wiedauwkaai 6 9000 Gent Belgium	Belgium	Active	4-(4-hydroxybenzenesulfonyl)phenol bis(tetraphenylphosphanium) bis(4-(4-hydroxybenzenesulfonyl)benzen-1-olate)	484-440-2	502157-74-6	2023	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	No longer Valid	4-(4-hydroxybenzenesulfonyl)phenol bis(tetraphenylphosphanium) bis(4-(4-hydroxybenzenesulfonyl)benzen-1-olate)	484-440-2	502157-74-6	2022	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide	425-850-3	125971-96-2	-	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide	425-850-3	125971-96-2	2012; 2013; 2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide	425-850-3	125971-96-2	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Cease Manufacture	4-(4-cyclopropyl-1-naphthyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione	943-285-5	1533519-84-4	2021	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid	810-200-7	1050477-45-6	2018; 2023	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide	810-201-2	1050477-27-4	2018; 2023	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione	258-858-9	53911-68-5	-	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	4-(4-chlorophenyl)-3-methyl-4-oxo-butanoic acid	610-810-1	52240-25-2	-	View substance registered dossier
Corteva Agriscience Italia S.r.l.	via dei Comizi Agrari 10 26100 Cremona (CR) Italy	Italy	Active	4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile	406-140-2	114369-43-6	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	No longer Valid	4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile	406-140-2	114369-43-6	2022	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol	925-590-5	-	-	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid	918-019-6	-	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	4-(4-chloro-1,2,5-thiadiazol-3-yl)morpholine	250-077-1	30165-96-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4-(4-chloro-1,2,5-thiadiazol-3-yl)morpholine	250-077-1	30165-96-9	-	View substance registered dossier
Curia France SAS	ZI de Laville 47240 BON-ENCONTRE France	France	Active	4-(4-bromo-3-formylphenoxy)benzonitrile	822-547-1	906673-54-9	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-(4-bromo-3-formylphenoxy)benzonitrile	822-547-1	906673-54-9	2019	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	4-(4-bromo-3-((tetrahydro-2H-pyran-2-yloxy)methyl)phenoxy)benzonitrile	807-693-6	943311-78-2	2015	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol	917-991-9	-	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol	919-822-4	-	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	4-(4-aminophenyl)morpholin-3-one	610-147-8	438056-69-0	2022	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide	608-211-5	284462-37-9	2021	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide	692-721-8	757251-39-1	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	4-(4-Allyloxy-benzenesulfonyl)-phenol	479-880-7	97042-18-7	-	View substance registered dossier
Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf)	Herzogstrasse 15 D-40217 Düsseldorf Germany	Germany	Active	4-(4-Allyloxy-benzenesulfonyl)-phenol	479-880-7	97042-18-7	2011; 2012; 2013; 2020	View substance registered dossier
Fine and Performance Chemicals Ltd	Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom	United Kingdom	No longer Valid	4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid	462-560-6	-	2021	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid	462-560-6	-	2013; 2015	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid	462-560-6	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride	447-230-1	3945-69-5	-	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Active	4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole	485-420-6	182918-16-7	2012	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole	485-420-6	182918-16-7	2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole	485-420-6	182918-16-7	-	View substance registered dossier
-	-	-	-	4-(4,4-dimethyl-3-oxo-pyrazolidin-1-yl)-benzoic acid	413-120-7	107144-30-9	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol	627-688-0	269409-70-3	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol	627-688-0	269409-70-3	2021	View substance registered dossier
-	-	-	-	4-(4'-Trifluoromethylphenyl)benzaldehyde	473-430-3	-	-	View substance registered dossier
Momentive Performance Materials GmbH	Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany	Germany	Active	4-(3-triethoxysilylpropoxy)-2-hydroxybenzophenone	431-490-8	79876-59-8	-	View substance registered dossier
Vertellus Specialties Belgium NV	Havenlaan 86-C- bus 204 1000 Brussels Belgium	Belgium	Active	4-(3-phenylpropyl)pyridine	218-159-1	2057-49-0	-	View substance registered dossier
SCAS Europe S.A./N.V.	Leonardo Da Vincilaan 19 B-1831 Diegem Belgium	Belgium	Active	4-(3-phenylpropyl)pyridine	218-159-1	2057-49-0	-	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	4-(3-methylbut-2-enyl)phenol	686-822-6	1200-09-5	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	-	View substance registered dossier
AromataGroup	Via Carolina Romani n. 35 20091 Bresso (MI) Italy	Italy	Active	4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	-	View substance registered dossier
REACH&Colours Kft	Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary	Hungary	Active	4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	2016	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid	201-901-3	89-36-1	-	View substance registered dossier
FINORGA SAS	497 route de Givors 38670 CHASSE SUR RHONE France	France	Active	4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ol	839-457-3	1269440-57-4	2020	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	4-(3-hydroxypropylamino)-1,3-dimethyluracil	252-128-3	34654-80-3	-	View substance registered dossier
SYNTHEXIM	1 Quai d'Amérique 62 100 calais France	France	Active	4-(3-hydroxypropoxy)benzoic acid	918-767-3	46350-87-2	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile	948-544-6	2141947-89-7	2019	View substance registered dossier
ZaCh System	ZI La Croix Cadeaux 49242 Avrillè France	France	Active	4-(3-Fluorbenzyloxy)benzaldehyde	613-982-6	66742-57-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	4-(3-Fluorbenzyloxy)benzaldehyde	613-982-6	66742-57-2	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(3-Fluorbenzyloxy)benzaldehyde	613-982-6	66742-57-2	2013; 2017; 2019	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Active	4-(3-chloropropyl)morpholine	461-510-0	7357-67-7	2012; 2014; 2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-(3-Butenyl)-4''-ethyl-2'-fluor-1,1':4',1''-terphenyl	619-966-5	825633-86-1	2022	View substance registered dossier

Showing 19,101 - 19,200 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.