Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
methyl 2-((benzyloxy)methyl)-4-bromo-1H-benzo[d]imidazole-6-carboxylate methanesulfonate
952-446-9 - Active Intermediate Individual Intermediate use only 28-05-2020 View substance registered dossier
Methyl 2-(2-nitrobenzylidene)acetoacetate
2-NITROBENZYLIDENE METHYL ESTER; BAY O 2787
400-650-9 39562-27-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 2-[(aminosulfonyl)methyl]benzoate
N 5297
419-010-5 112941-26-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
methyl 2-[(ethoxycarbonothioyl)thio]propanoate
435-690-6 344562-80-7 Cease Manufacture NONS Individual Cease manufacture 19-08-2011 View substance registered dossier
Methyl 2-aminosulfonyl-6-(trifluoromethyl)pyridine-3-c arboxylate
JE 127
421-220-7 144740-59-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 2-benzoylamino-2-deoxy-α-D-glucopyranoside
METHYL-N-BENZOYL GLUCOSAMINE
417-860-1 6863-90-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
methyl 2-chlorosulfonyl-4-(methanesulfonylaminomethyl) benzoate
443-120-2 393509-79-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Methyl 2-fluoro-3-oxopentanoate
817-369-6 180287-02-9 No longer Valid Intermediate Individual No longer valid 02-05-2018 View substance registered dossier
Methyl 2-hydroxy-2-(1-oxo-2-propenylamino)acetate
MAGME(R) 200 MONOMER
403-230-3 77402-05-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 2-methoxy-2-[1-oxo-2-(propenyl)amino]acetate
MAGME 100 MONOMEER
401-890-7 77402-03-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 2-oxopyrrolidin-1-acetate
261-926-0 59776-88-4 Active Intermediate Individual Intermediate use only 31-05-2013 View substance registered dossier
Methyl 2R,3S-(-)-3-(4-methoxyphenyl)oxiranecarboxylate
MEFAT
404-130-2 105560-93-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
methyl 3-(2-morpholinocyclopenten-1-yl)propanoate
949-350-4 - Active Intermediate Individual Intermediate use only 25-07-2019 View substance registered dossier
Methyl 3-(acetylthio)-2-methylpropanoate
D,L-ESTER
411-040-7 97101-46-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate
400-820-2 84268-33-7 Active Full Individual ≥ 1 to < 10 tonnes 05-10-2016 View substance registered dossier
Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate
400-820-2 84268-33-7 Active Intermediate Individual Intermediate use only 27-03-2015 View substance registered dossier
Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate
400-820-2 84268-33-7 Active Intermediate Individual Intermediate use only 30-06-2014 View substance registered dossier
methyl 3-amino-2,2,3-trimethylbutyrate
431-720-7 90886-53-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 3-carbamimidamido-4-methylbenzoate carbonate (2:1)
700-745-8 1388148-32-0 Active Intermediate Individual Intermediate use only 17-01-2012 View substance registered dossier
Methyl 3-isocyanatosulfonyl-2-thiophenecarboxylate
F7641; MTSI
410-550-7 79277-18-2 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Methyl 3-mercaptopropionate
220-912-4 2935-90-2 Cease Manufacture Intermediate Individual Cease manufacture 09-09-2010 View substance registered dossier
Methyl 3-mercaptopropionate
220-912-4 2935-90-2 Active Intermediate Individual Intermediate use only 15-03-2013 View substance registered dossier
Methyl 3-mercaptopropionate
220-912-4 2935-90-2 Active Intermediate Individual Intermediate use only 25-11-2014 View substance registered dossier
Methyl 3-sulfamoyl-2-thiophenecarboxylate
A5546
402-050-2 59337-93-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 3-α,7-α-diacetoxy-12-oxo-5-β-cholan-24-oate
249-070-6 28535-81-1 Active Full Individual ≥ 10 to < 100 tonnes 24-05-2013 View substance registered dossier
Methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate
223-151-6 3749-87-9 Active Full Individual ≥ 10 to < 100 tonnes 23-05-2013 View substance registered dossier
Methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate
223-151-6 3749-87-9 Active Intermediate Individual Intermediate use only 28-05-2013 View substance registered dossier
Methyl 4-(1-((2-chloro-5-(4-(2,4-di-tert-pentylphenoxy)butyramido)phenyl)carbamoyl)-3,3-dimethyl-2-oxobutoxy)-3-methylsulfonamidobenzoate
APF
401-960-7 86841-17-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl 4-(butylamino)benzoate
700-310-2 71839-12-8 Active Intermediate Individual Intermediate use only 19-11-2009 View substance registered dossier
Methyl 4-bromobenzoate
210-596-6 619-42-1 Active Intermediate Individual Intermediate use only 30-11-2016 View substance registered dossier
Methyl 4-bromomethyl-3-methoxybenzoate
BROMBENZOAT; BROMOBENZOATE
410-310-1 70264-94-7 No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
Methyl 4-tert-butylbenzoate
247-768-5 26537-19-9 Active Intermediate Individual Intermediate use only 11-09-2019 View substance registered dossier
Methyl 5-chlorosalicylate
223-778-5 4068-78-4 Active Intermediate Individual Intermediate use only 31-05-2017 View substance registered dossier
Methyl 5-methyl-1,2-oxazole-4-carboxylate
600-020-5 100047-54-9 Active Intermediate Individual Intermediate use only 14-06-2018 View substance registered dossier
methyl [(2S)-1-{[4-(3-{5-chloro-3-[(diphenylmethylene)amino]-2-fluorophenyl}-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl]amino}propan-2-yl]carbamate
941-175-1 - Active Intermediate Individual Intermediate use only 13-11-2015 View substance registered dossier
Methyl [[(methoxycarbonyl)amino](methylthio)methylene]carbamate
252-240-2 34840-23-8 Active Intermediate Individual Intermediate use only 11-11-2015 View substance registered dossier
Methyl [S-(E)]-2-[3-[3-[2-(7-chloro-quinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate monohydrate
HYDROXY ESTER
431-050-5 287930-78-3 Active NONS Individual Tonnage data confidential 28-04-2011 View substance registered dossier
Methyl acetoacetate
203-299-8 105-45-3 Active Intermediate Individual Intermediate use only 14-11-2013 View substance registered dossier
Methyl benzoate
202-259-7 93-58-3 Cease Manufacture Intermediate Individual Cease manufacture 12-04-2013 View substance registered dossier
Methyl benzoylformate
239-263-3 15206-55-0 Cease Manufacture Intermediate Individual Cease manufacture 18-04-2013 View substance registered dossier
Methyl chloroformate
201-187-3 79-22-1 Active Intermediate Individual Intermediate use only 15-10-2012 View substance registered dossier
Methyl cholate
215-903-7 1448-36-8 Active Intermediate Individual Intermediate use only 28-05-2013 View substance registered dossier
Methyl cyanoacetate
203-288-8 105-34-0 Active Intermediate Individual Intermediate use only 28-05-2013 View substance registered dossier
Methyl cyclohexylacetate
700-789-8 14352-61-5 Active Full Individual ≥ 1 to < 10 tonnes 31-08-2012 View substance registered dossier
Methyl dichloroacetate
204-146-8 116-54-1 Active Intermediate Individual Intermediate use only 31-05-2016 View substance registered dossier
Methyl DL-serinate hydrochloride
227-047-1 5619-04-5 Active Intermediate Individual Intermediate use only 22-03-2018 View substance registered dossier
Methyl dodec-9-enoate
700-618-7 39202-17-0 Active Full Individual ≥ 1 000 to < 10 000 tonnes 15-04-2016 View substance registered dossier
Methyl ester of fatty acids, Cx-Cy, Hydroxymethylated
- - Active Full Individual ≥ 100 to < 1 000 tonnes 20-02-2013 View substance registered dossier
Methyl esters of fatty acids, C16-C18 and C18 unsaturated, branched and linear
457-390-4 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
methyl heptamethyl-oxo-hexadecahydropiceno carboxylate
- - Active Intermediate Individual Intermediate use only 14-01-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active methyl 2-((benzyloxy)methyl)-4-bromo-1H-benzo[d]imidazole-6-carboxylate methanesulfonate 952-446-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active Methyl 2-(2-nitrobenzylidene)acetoacetate 400-650-9 39562-27-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 2-[(aminosulfonyl)methyl]benzoate 419-010-5 112941-26-1 - View substance registered dossier
BASF Italia S.p.A. OR15 Via Marconato 8 20811 Cesano Maderno Italy Italy Cease Manufacture methyl 2-[(ethoxycarbonothioyl)thio]propanoate 435-690-6 344562-80-7 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 2-aminosulfonyl-6-(trifluoromethyl)pyridine-3-c arboxylate 421-220-7 144740-59-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 2-benzoylamino-2-deoxy-α-D-glucopyranoside 417-860-1 6863-90-7 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture methyl 2-chlorosulfonyl-4-(methanesulfonylaminomethyl) benzoate 443-120-2 393509-79-0 2014 View substance registered dossier
F2 Chemicals Ltd Lea Lane Lea Town PR4 0RZ Preston Lancashire United Kingdom United Kingdom No longer Valid Methyl 2-fluoro-3-oxopentanoate 817-369-6 180287-02-9 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Methyl 2-hydroxy-2-(1-oxo-2-propenylamino)acetate 403-230-3 77402-05-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Methyl 2-methoxy-2-[1-oxo-2-(propenyl)amino]acetate 401-890-7 77402-03-0 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active Methyl 2-oxopyrrolidin-1-acetate 261-926-0 59776-88-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Methyl 2R,3S-(-)-3-(4-methoxyphenyl)oxiranecarboxylate 404-130-2 105560-93-8 - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active methyl 3-(2-morpholinocyclopenten-1-yl)propanoate 949-350-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Methyl 3-(acetylthio)-2-methylpropanoate 411-040-7 97101-46-7 - View substance registered dossier
Chemservice S.A. (8LF5) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate 400-820-2 84268-33-7 2016 View substance registered dossier
Rianlon GmbH Charlottenstr. 75 40210 Duesseldorf Germany Germany Active Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate 400-820-2 84268-33-7 - View substance registered dossier
[Confidential] - - - Methyl 3-[3-(2H-benzotriazol-2-yl)-4-hydroxy-5-(2-methyl-2-propanyl)phenyl]propanoate 400-820-2 84268-33-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active methyl 3-amino-2,2,3-trimethylbutyrate 431-720-7 90886-53-6 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active Methyl 3-carbamimidamido-4-methylbenzoate carbonate (2:1) 700-745-8 1388148-32-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 3-isocyanatosulfonyl-2-thiophenecarboxylate 410-550-7 79277-18-2 - View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture Methyl 3-mercaptopropionate 220-912-4 2935-90-2 2019 View substance registered dossier
THOR GmbH Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany Germany Active Methyl 3-mercaptopropionate 220-912-4 2935-90-2 - View substance registered dossier
Galata Chemicals GmbH Chemiestrasse 22 68623 Lampertheim 06 Germany Germany Active Methyl 3-mercaptopropionate 220-912-4 2935-90-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 3-sulfamoyl-2-thiophenecarboxylate 402-050-2 59337-93-8 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active Methyl 3-α,7-α-diacetoxy-12-oxo-5-β-cholan-24-oate 249-070-6 28535-81-1 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active Methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate 223-151-6 3749-87-9 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active Methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate 223-151-6 3749-87-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Methyl 4-(1-((2-chloro-5-(4-(2,4-di-tert-pentylphenoxy)butyramido)phenyl)carbamoyl)-3,3-dimethyl-2-oxobutoxy)-3-methylsulfonamidobenzoate 401-960-7 86841-17-0 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active Methyl 4-(butylamino)benzoate 700-310-2 71839-12-8 2009 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active Methyl 4-bromobenzoate 210-596-6 619-42-1 - View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom No longer Valid Methyl 4-bromomethyl-3-methoxybenzoate 410-310-1 70264-94-7 2021 View substance registered dossier
Merck S.L.U. Calle Maria de Molina 28006 Madrid Spain Spain Active Methyl 4-tert-butylbenzoate 247-768-5 26537-19-9 2013; 2014; 2019 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Methyl 5-chlorosalicylate 223-778-5 4068-78-4 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active Methyl 5-methyl-1,2-oxazole-4-carboxylate 600-020-5 100047-54-9 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active methyl [(2S)-1-{[4-(3-{5-chloro-3-[(diphenylmethylene)amino]-2-fluorophenyl}-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl]amino}propan-2-yl]carbamate 941-175-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Methyl [[(methoxycarbonyl)amino](methylthio)methylene]carbamate 252-240-2 34840-23-8 - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active Methyl [S-(E)]-2-[3-[3-[2-(7-chloro-quinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate monohydrate 431-050-5 287930-78-3 2011 View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active Methyl acetoacetate 203-299-8 105-45-3 - View substance registered dossier
Indorama Ventures Polymers Germany GmbH Philipp Reis Strasse 4 65795 Hattersheim Germany Germany Cease Manufacture Methyl benzoate 202-259-7 93-58-3 2015 View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture Methyl benzoylformate 239-263-3 15206-55-0 2021 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Methyl chloroformate 201-187-3 79-22-1 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active Methyl cholate 215-903-7 1448-36-8 - View substance registered dossier
Katwijk Chemie BV Snijderstraat 6 Steenbakkerstraat 26 2222 BA Katwijk ZH Netherlands Netherlands Active Methyl cyanoacetate 203-288-8 105-34-0 - View substance registered dossier
PFW Aroma Ingredients BV Veemweg 29-31 3771 MT Barneveld Netherlands Netherlands Active Methyl cyclohexylacetate 700-789-8 14352-61-5 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active Methyl dichloroacetate 204-146-8 116-54-1 - View substance registered dossier
SP QUIMICA SA Crta. Reus a Riudoms Km. 4, 1 43330 RIUDOMS TARRAGONA Spain Spain Active Methyl DL-serinate hydrochloride 227-047-1 5619-04-5 - View substance registered dossier
Wilmar Europe Trading B.V. Central Post – Entrance West, 7th floor Delftseplein 27G 3013 AA Rotterdam Netherlands Netherlands Active Methyl dodec-9-enoate 700-618-7 39202-17-0 2014; 2015; 2016 View substance registered dossier
Only representative (No publishable name) - - Active Methyl ester of fatty acids, Cx-Cy, Hydroxymethylated - - 2009; 2010; 2011; 2013 View substance registered dossier
Kraton Chemical Ltd Vigo Lane DH3 2RB Chester-le-Street Co.Durham United Kingdom United Kingdom No longer Valid Methyl esters of fatty acids, C16-C18 and C18 unsaturated, branched and linear 457-390-4 - 2021 View substance registered dossier
[Confidential] - - - methyl heptamethyl-oxo-hexadecahydropiceno carboxylate - - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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