Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?)
440-050-4 243857-97-8 Cease Manufacture NONS Individual Cease manufacture 20-12-2010 View substance registered dossier
1,8-bis(4-dodecylphenyl)amino-9,10-anthracenedione
VIOLETTO SOMALIA LV 100%
403-820-0 42887-23-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1,8-diisocyanato-4-isocyanatomethyloctane
4-METHYLISOCYANATO-1,8-OCTAMETHYLENDIISOCYANAT
429-140-4 79371-37-2 Cease Manufacture NONS Individual Cease manufacture 19-02-2009 View substance registered dossier
1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione
PTH-SUCCINIMIDESTER
418-630-3 136465-99-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1-((3-(3-chloro-4-fluorophenyl)propyl)dimethylsilanyl)-4-ethoxybenzene
SILAN DMS
412-620-2 121626-74-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1-((4-methoxyphenyl)ethynyl)-4-(trans-4-propylcyclohexyl)benzene
LICRISTAL ZLI-4209
433-760-0 116903-47-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(1,1-dimethylpropyl)-4-ethoxy-trans-cyclohexane;reaction mass of: 1-(1,1-dimethylpropyl)-4-ethoxy-cis-cyclohexane
426-530-6 - Active NONS Individual Tonnage data confidential 29-05-2012 View substance registered dossier
1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride
DOXAZOSIN 4; DOXAZOSIN STEP 4
415-660-9 70918-74-0 Active NONS Joint Tonnage data confidential 22-03-2011 View substance registered dossier
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7 65322-65-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2,3-dihydro-1,3,3,6-tetramethyl-1-(1-methylethyl)-1H-inden-5-yl)ethanone
ACYLINDANE
411-180-9 92836-10-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone methanesulfonate
431-010-7 154486-26-7 Cease Manufacture NONS Individual Cease manufacture 23-09-2010 View substance registered dossier
1-(2,4-dichlorophenylcarbamoyl)cyclopropancarboxylic acid
CSDCA
419-150-7 113136-77-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
TETRAFLUOROQUINOLONE
406-710-0 103995-01-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2,5-dichloro-4-(N-methylsulfamoyl)phenylazo)-2-hydroxy-N-(2-tolyl)-3-naphthamide
ROUGE GRAPHTOL GLF
400-840-1 85776-13-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2,6-bis(4-tolyl)-1,3-dioxano(5,4-d)-1,3-dioxan-4-yl)ethane-1,2-diol
CLEARLITE NU 005; DISORBENE M; GENISET MD; GLC NU 005; MILLAD 3940; NU 005
402-950-5 87826-41-3 Active NONS Joint Tonnage data confidential 14-10-2011 View substance registered dossier
1-(2-(ethyl(4-(4-(4-(4-(ethyl(2-pyridinoethyl)amino)-2-methylphenylazo)benzoylamino)-phenylazo)-3-methylphenyl)amino)ethyl-pyridinium dichloride
ORANGE DK 2764
420-950-3 163831-67-2 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;[containing < 0.1 % 4-chloroaniline (EC No 203-401-0)];[containing ≥ 0.1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2 214353-17-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2-bromoethoxy)-2-methoxybenzene
GUAIACOL-O-ETHYLBROMIDE
402-010-4 4463-59-6 Cease Manufacture NONS Individual Cease manufacture 30-08-2010 View substance registered dossier
1-(2-chloroethoxy)-4-nitrobenzene
UK-8,793
425-790-8 3383-72-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1-(2-deoxy-5-O-trityl-β-D-threopentofuranosyl)thymine
741U85
407-120-6 55612-11-8 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
1-(2-hydroxy-5-methylphenyl)dodecan-1-one oxime
LAUROPHENON-OXIM; LPO
433-200-5 50652-76-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate
PYRAZOL P5; PYRAZOLE DHE
429-300-3 155601-30-2 Active NONS Joint Tonnage data confidential 03-01-2012 View substance registered dossier
1-(2-isopropylphenyl)-1-phenylethane;1-(3-isopropylphenyl)-1-phenylethane;reaction mass of: 1-(4-isopropylphenyl)-1-phenylethane
430-690-2 52783-21-8 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
1-(3,3-dimethylcyclohexyl)pent-4-en-1-one
GALBANIFF
422-330-8 56973-87-6 Active NONS Joint Tonnage data confidential 08-05-2012 View substance registered dossier
1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinone
T1314
411-500-7 116256-11-2 Cease Manufacture NONS Individual Cease manufacture 26-05-2010 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
CFB Chemische Fabrik Brunsbüttel GmbH Kühlturmstrasse 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Cease Manufacture 1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?) 440-050-4 243857-97-8 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 1,8-bis(4-dodecylphenyl)amino-9,10-anthracenedione 403-820-0 42887-23-0 - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Cease Manufacture 1,8-diisocyanato-4-isocyanatomethyloctane 429-140-4 79371-37-2 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione 418-630-3 136465-99-1 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active 1-((3-(3-chloro-4-fluorophenyl)propyl)dimethylsilanyl)-4-ethoxybenzene 412-620-2 121626-74-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 1-((3-(3-chloro-4-fluorophenyl)propyl)dimethylsilanyl)-4-ethoxybenzene 412-620-2 121626-74-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 1-((4-methoxyphenyl)ethynyl)-4-(trans-4-propylcyclohexyl)benzene 433-760-0 116903-47-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-(1,1-dimethylpropyl)-4-ethoxy-trans-cyclohexane;reaction mass of: 1-(1,1-dimethylpropyl)-4-ethoxy-cis-cyclohexane 426-530-6 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 2021 View substance registered dossier
ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 - View substance registered dossier
Schlumberger Offshore Services N.V. 1 rue Henri Becquerel – BP 202 92142 Clamart Netherlands Netherlands Active 1-(1-naphthylmethyl)quinolinium chloride 406-220-7 65322-65-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 1-(2,3-dihydro-1,3,3,6-tetramethyl-1-(1-methylethyl)-1H-inden-5-yl)ethanone 411-180-9 92836-10-7 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone methanesulfonate 431-010-7 154486-26-7 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 1-(2,4-dichlorophenylcarbamoyl)cyclopropancarboxylic acid 419-150-7 113136-77-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(2,4-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 406-710-0 103995-01-3 - View substance registered dossier
Clariant Production (France) S.A.S. Rue Louise Michel 6 94603 CHOISY LE ROI France France Active 1-(2,5-dichloro-4-(N-methylsulfamoyl)phenylazo)-2-hydroxy-N-(2-tolyl)-3-naphthamide 400-840-1 85776-13-2 - View substance registered dossier
RiKA International Limited 3 Howarth Court, Gateway Crescent Broadway Business Park OL9 9XB Chadderton Oldham United Kingdom United Kingdom No longer Valid 1-(2,6-bis(4-tolyl)-1,3-dioxano(5,4-d)-1,3-dioxan-4-yl)ethane-1,2-diol 402-950-5 87826-41-3 2021 View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture 1-(2,6-bis(4-tolyl)-1,3-dioxano(5,4-d)-1,3-dioxan-4-yl)ethane-1,2-diol 402-950-5 87826-41-3 2018 View substance registered dossier
Milliken Europe B.V. Ham 18-24 9000 Gent Belgium Belgium Active 1-(2,6-bis(4-tolyl)-1,3-dioxano(5,4-d)-1,3-dioxan-4-yl)ethane-1,2-diol 402-950-5 87826-41-3 2010 View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as OR for LANXESS Solutions UK Ltd Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland Ireland Cease Manufacture 1-(2,6-bis(4-tolyl)-1,3-dioxano(5,4-d)-1,3-dioxan-4-yl)ethane-1,2-diol 402-950-5 87826-41-3 2018 View substance registered dossier
BASF Grenzach GmbH Köchlinstr. 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture 1-(2-(ethyl(4-(4-(4-(4-(ethyl(2-pyridinoethyl)amino)-2-methylphenylazo)benzoylamino)-phenylazo)-3-methylphenyl)amino)ethyl-pyridinium dichloride 420-950-3 163831-67-2 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Finnish competent national authority. - - Active 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;[containing < 0.1 % 4-chloroaniline (EC No 203-401-0)];[containing ≥ 0.1 % 4-chloroaniline (EC No 203-401-0)] 433-580-2 214353-17-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;[containing < 0.1 % 4-chloroaniline (EC No 203-401-0)];[containing ≥ 0.1 % 4-chloroaniline (EC No 203-401-0)] 433-580-2 214353-17-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride;[containing < 0.1 % 4-chloroaniline (EC No 203-401-0)];[containing ≥ 0.1 % 4-chloroaniline (EC No 203-401-0)] 433-580-2 214353-17-0 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Cease Manufacture 1-(2-bromoethoxy)-2-methoxybenzene 402-010-4 4463-59-6 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 1-(2-chloroethoxy)-4-nitrobenzene 425-790-8 3383-72-0 - View substance registered dossier
- - - - 1-(2-chloroethoxy)-4-nitrobenzene 425-790-8 3383-72-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(2-deoxy-5-O-trityl-β-D-threopentofuranosyl)thymine 407-120-6 55612-11-8 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 1-(2-deoxy-5-O-trityl-β-D-threopentofuranosyl)thymine 407-120-6 55612-11-8 2021 View substance registered dossier
- - - - 1-(2-hydroxy-5-methylphenyl)dodecan-1-one oxime 433-200-5 50652-76-1 - View substance registered dossier
Henkel AG & Co.KGaA - Non Phase In Substances Henkelstrasse 67 40589 Duesseldorf Germany Germany Cease Manufacture 1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate 429-300-3 155601-30-2 2016 View substance registered dossier
Wella Service GmbH_2 Berliner Allee 65 64274 Darmstadt Germany Germany Active 1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate 429-300-3 155601-30-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(2-isopropylphenyl)-1-phenylethane;1-(3-isopropylphenyl)-1-phenylethane;reaction mass of: 1-(4-isopropylphenyl)-1-phenylethane 430-690-2 52783-21-8 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-(3,3-dimethylcyclohexyl)pent-4-en-1-one 422-330-8 56973-87-6 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 1-(3,3-dimethylcyclohexyl)pent-4-en-1-one 422-330-8 56973-87-6 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinone 411-500-7 116256-11-2 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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