Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
941-760-1 1297537-33-7 Active Intermediate Individual Intermediate use only 04-01-2018 View substance registered dossier
(S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride
948-271-2 - Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
(S)-5-fluoro-3-methylisobenzofuran-1(3H)-one
943-180-4 1803573-19-4 Active Intermediate Joint Intermediate use only 11-09-2019 View substance registered dossier
(S)-5-Methoxy-2-propionamidotetralin
607-376-0 244239-67-6 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
(S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester
811-219-3 1681053-95-1 Active Intermediate Individual Intermediate use only 28-02-2018 View substance registered dossier
(S)-7-[[2-O-6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
236-216-9 13241-33-3 Active Full Joint ≥ 10 to < 100 tonnes 13-11-2017 View substance registered dossier
(S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether
471-940-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-7-hydroxy-3,7-dimethyloctanal
829-246-4 34212-53-8 Active Full Joint ≥ 1 to < 10 tonnes 22-03-2019 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Active Intermediate Joint Intermediate use only 08-07-2015 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1)
617-437-3 83113-55-7 Active Intermediate Joint Intermediate use only 20-11-2020 View substance registered dossier
(S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride
433-010-2 2135910-74-4 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active Intermediate Individual Intermediate use only 19-06-2018 View substance registered dossier
(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate
815-198-1 934240-38-7 Active Intermediate Joint Intermediate use only 14-03-2018 View substance registered dossier
(S)-methyl-2-chloropropionate
L (-) CHLOROPROPIONATE DE METHYLE; S (-) CHLOROPROPIONATE DE METHYLE
412-470-8 73246-45-4 Active Intermediate Joint Intermediate use only 05-06-2020 View substance registered dossier
(S)-N,N'-dibutyl-2-[(1-oxododecyl)amino]glutaramide
264-391-1 63663-21-8 Active Full Joint ≥ 0 to < 10 tonnes 02-05-2018 View substance registered dossier
(S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine
942-077-1 - Active Intermediate Joint Intermediate use only 18-01-2018 View substance registered dossier
(S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
CZ-AMIDE; PTH-TETRAHYDROAMIDE; TETRAHYDROAMIDE (THA)
414-600-9 149182-72-9 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-Neopentyl 3-(benzyloxycarbonylamino) 4-(methylsulfonyloxy)butane 1-sulfonate
858-354-4 1370348-25-6 Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(S)-p-mentha-1,8-diene
227-815-6 5989-54-8 Active Full Joint ≥ 100 to < 1 000 tonnes 28-09-2021 View substance registered dossier
(S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate
924-425-4 - Active Intermediate Joint Intermediate use only 07-08-2020 View substance registered dossier
(S)-pyrrolidine-2-carboxamide
231-397-0 7531-52-4 Active Intermediate Joint Intermediate use only 30-10-2018 View substance registered dossier
(S)-tert-butyl 5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate
848-455-1 1398610-06-4 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2021 View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate
942-159-7 - Cease Manufacture Intermediate Individual Cease manufacture 20-07-2015 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide 941-760-1 1297537-33-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride 948-271-2 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (S)-5-fluoro-3-methylisobenzofuran-1(3H)-one 943-180-4 1803573-19-4 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (S)-5-Methoxy-2-propionamidotetralin 607-376-0 244239-67-6 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester 811-219-3 1681053-95-1 - View substance registered dossier
[Confidential] - - - (S)-7-[[2-O-6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one 236-216-9 13241-33-3 - View substance registered dossier
- - - - (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether 471-940-0 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (S)-7-hydroxy-3,7-dimethyloctanal 829-246-4 34212-53-8 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1) 617-437-3 83113-55-7 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active (S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1) 617-437-3 83113-55-7 - View substance registered dossier
AstraZeneca B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden Sweden Cease Manufacture (S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride 433-010-2 2135910-74-4 2012 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate 815-198-1 934240-38-7 - View substance registered dossier
CABB Oy (OR of CABB AG) Kemirantie 1 P.O.Box 566 Kokkola Finland Finland Active (S)-methyl-2-chloropropionate 412-470-8 73246-45-4 - View substance registered dossier
Ajinomoto OmniChem (OR) Cooppallaan 91 9230 Wetteren Belgium Belgium Active (S)-N,N'-dibutyl-2-[(1-oxododecyl)amino]glutaramide 264-391-1 63663-21-8 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine 942-077-1 - - View substance registered dossier
ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide 414-600-9 149182-72-9 - View substance registered dossier
- - - - (S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide 414-600-9 149182-72-9 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)-Neopentyl 3-(benzyloxycarbonylamino) 4-(methylsulfonyloxy)butane 1-sulfonate 858-354-4 1370348-25-6 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (S)-p-mentha-1,8-diene 227-815-6 5989-54-8 2019 View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (S)-p-mentha-1,8-diene 227-815-6 5989-54-8 2017 View substance registered dossier
[Confidential] - - - (S)-p-mentha-1,8-diene 227-815-6 5989-54-8 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (S)-p-mentha-1,8-diene 227-815-6 5989-54-8 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (S)-pyrrolidine-2-carboxamide 231-397-0 7531-52-4 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-pyrrolidine-2-carboxamide 231-397-0 7531-52-4 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-pyrrolidine-2-carboxamide 231-397-0 7531-52-4 2018 View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (S)-tert-butyl 5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 848-455-1 1398610-06-4 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate 942-159-7 - 2017 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Tagged as:

(click the tag to search for relevant content)

EU Privacy Disclaimer

This website uses cookies to ensure you get the best experience on our websites.