Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(R,R)-(-)-butane-2,3-diol
246-186-9 24347-58-8 Active Full Joint ≥ 1 to < 10 tonnes 02-05-2019 View substance registered dossier
(R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate
445-750-3 839705-03-2 Active Intermediate Individual Intermediate use only 16-04-2013 View substance registered dossier
(R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate
445-750-3 839705-03-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-2-amino-3,3-dimethylbutane amide
447-860-7 144177-62-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one
421-830-3 49805-30-3 Active NONS Joint Tonnage data confidential 08-12-2010 View substance registered dossier
(R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one
421-830-3 49805-30-3 Active Intermediate Joint Intermediate use only 28-09-2020 View substance registered dossier
(R,S)-2-butyloctanedioic acid
2-BUTYLOCTANEDIOIC ACID
431-210-4 50905-10-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-780-1 103146-25-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate
430-790-6 658080-64-9 Active Intermediate Joint Intermediate use only 05-05-2015 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate
430-790-6 658080-64-9 Active Intermediate Joint Intermediate use only 01-05-2018 View substance registered dossier
(RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol
HEXACONAZOLE
413-050-7 79983-71-4 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(RS)-2-methylbutyryl chloride
260-787-3 57526-28-0 Active Intermediate Joint Intermediate use only 25-07-2017 View substance registered dossier
(RS)-3-Allyl-2-methyl-4-oxocyclopent-2- enyl (1R,3R)-2,2-dimethyl-3-(2-methyl prop-1-enyl)-cyclopropanecarboxylate (mixture of 2 isomers 1R trans: 1R/S only 1:3) (Esbiothrin)
807-421-6 260359-57-7 Active Full Joint ≥ 1 to < 10 tonnes 11-11-2020 View substance registered dossier
(S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt
918-890-2 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(S) 2-(Benzyloxycarbonylamino) 4-(neopentyloxysulfonyl)butyl thioacetate
873-888-8 1370348-26-7 Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(S)- 3-[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxy]-pyrrolidine hydrochloride
948-439-5 2114341-27-2 Active Intermediate Joint Intermediate use only 15-12-2020 View substance registered dossier
(S)- 3[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxyl]-pyrrolidine -1-carboxylic tert butyl ether
861-843-5 1383793-75-6 Active Intermediate Joint Intermediate use only 16-12-2020 View substance registered dossier
(S)-(+)-1-methoxy-2-propylamine
700-220-3 99636-32-5 Active Intermediate Individual Intermediate use only 30-09-2010 View substance registered dossier
(S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt
600-817-8 1073145-07-9 Active Intermediate Joint Intermediate use only 22-01-2018 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - No longer Valid Intermediate Individual No longer valid 22-09-2011 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate
257-581-0 51988-14-8 Active Full Joint ≥ 1 to < 10 tonnes 24-10-2019 View substance registered dossier
(S)-1,1-diphenyl-1,2-propanediol
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(S)-1,2,4-butanetriyltrimethanesulfonate
UK-164,608
433-850-1 99520-81-7 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-1,2-epoxypropane
240-241-0 16088-62-3 Active Intermediate Joint Intermediate use only 16-12-2010 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
SCC Scientific Consulting Company GmbH Am Grenzgraben 11 55545 Bad Kreuznach Germany Germany Active (R,R)-(-)-butane-2,3-diol 246-186-9 24347-58-8 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate 445-750-3 839705-03-2 2013 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate 445-750-3 839705-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate 445-750-3 839705-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (R,S)-2-amino-3,3-dimethylbutane amide 447-860-7 144177-62-8 - View substance registered dossier
Mitsui & Co. Europe PLC London Branch 1 St Martin's Le Grand EC1A 4AS London United Kingdom United Kingdom No longer Valid (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Lonza Cologne GmbH - REACH Nattermannallee 1 50829 Cologne Germany Germany Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Vishay BCcomponents B.V. Ceintuurbaan 15 8022 AW Zwolle Netherlands Netherlands Active (R,S)-2-butyloctanedioic acid 431-210-4 50905-10-7 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 2015 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 2015; 2018 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol 413-050-7 79983-71-4 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (RS)-2-methylbutyryl chloride 260-787-3 57526-28-0 - View substance registered dossier
ENDURA S.p.A. Viale Pietramellara, 5 40121 Bologna Italy Italy Active (RS)-3-Allyl-2-methyl-4-oxocyclopent-2- enyl (1R,3R)-2,2-dimethyl-3-(2-methyl prop-1-enyl)-cyclopropanecarboxylate (mixture of 2 isomers 1R trans: 1R/S only 1:3) (Esbiothrin) 807-421-6 260359-57-7 - View substance registered dossier
Bábolna Bioenvironmental Centre Ltd. Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt 918-890-2 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S) 2-(Benzyloxycarbonylamino) 4-(neopentyloxysulfonyl)butyl thioacetate 873-888-8 1370348-26-7 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)- 3-[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxy]-pyrrolidine hydrochloride 948-439-5 2114341-27-2 2020 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)- 3[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxyl]-pyrrolidine -1-carboxylic tert butyl ether 861-843-5 1383793-75-6 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (S)-(+)-1-methoxy-2-propylamine 700-220-3 99636-32-5 2010 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt 600-817-8 1073145-07-9 - View substance registered dossier
Carbogen Amcis Ltd 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - - View substance registered dossier
[Confidential] - - - (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate 257-581-0 51988-14-8 - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-1,1-diphenyl-1,2-propanediol 443-220-6 46755-94-6 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-1,2,4-butanetriyltrimethanesulfonate 433-850-1 99520-81-7 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (S)-1,2-epoxypropane 240-241-0 16088-62-3 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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