Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene
- - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
(1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate
- - Active Intermediate Joint Intermediate use only 14-11-2017 View substance registered dossier
(2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid
- - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
- - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one
- - Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
(aminoalkyl) hydrogen thiosulfate
- - Active Full Joint ≥ 1 to < 10 tonnes 05-01-2021 View substance registered dossier
(E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid
- - Active Intermediate Joint Intermediate use only 30-03-2022 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane
- 37486-69-4 Active Full Individual ≥ 1 to < 10 tonnes 06-05-2019 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-15-[[(1,1-dimethylethoxy)carbonyl]amino]-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H) -carboxylic acid ethyl ester (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 23-09-2013 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 17-09-2013 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid ethyl ester hydrochloride (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w)
- - Active Full Individual ≥ 0 to < 10 tonnes 24-01-2019 View substance registered dossier
1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate
- - Active Intermediate Joint Intermediate use only 05-06-2014 View substance registered dossier
1,4-bis(alkenyl(dialkyl)siliyl)heteromonocycle
- - Active Intermediate Joint Intermediate use only 04-02-2021 View substance registered dossier
1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester
- 313644-32-5 Active Full Joint ≥ 10 to < 100 tonnes 21-08-2018 View substance registered dossier
1-(3-tert-butyl-1,3,3-trimethyl-1-alkenyldisiloxanyl)-4-alkylheterocycle
- - Active Intermediate Joint Intermediate use only 23-11-2020 View substance registered dossier
1-[3-[4-(4-cyanophenyl)-heteromonocycle-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-heteromonocycle-4-ium chloride
- - Active Intermediate Individual Intermediate use only 12-04-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene - - - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol - - - View substance registered dossier
[Confidential] - - - (1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate - - - View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate - - - View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one - - - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one - - 2022 View substance registered dossier
RSI ChemRep Europe Ltd (S001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active (aminoalkyl) hydrogen thiosulfate - - 2017; 2021 View substance registered dossier
[Confidential] - - - (E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone - - - View substance registered dossier
[Confidential] - - - (E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one - - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid - - - View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
[Confidential] - - - 1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane - 37486-69-4 - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-15-[[(1,1-dimethylethoxy)carbonyl]amino]-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H) -carboxylic acid ethyl ester (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid ethyl ester hydrochloride (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Active 1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w) - - 2017; 2018; 2019 View substance registered dossier
[Confidential] - - - 1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate - - - View substance registered dossier
GRACE GmbH In der Hollerhecke 1 67545 Worms Germany Germany Active 1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate - - 2014 View substance registered dossier
[Confidential] - - - 1,4-bis(alkenyl(dialkyl)siliyl)heteromonocycle - - - View substance registered dossier
[Confidential] - - - 1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester - 313644-32-5 - View substance registered dossier
[Confidential] - - - 1-(3-tert-butyl-1,3,3-trimethyl-1-alkenyldisiloxanyl)-4-alkylheterocycle - - - View substance registered dossier
[Confidential] - - - 1-[3-[4-(4-cyanophenyl)-heteromonocycle-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-heteromonocycle-4-ium chloride - - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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