Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol
919-949-5 - Active Full Joint ≥ 0 to < 10 tonnes 17-12-2021 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active Full Joint ≥ 1 to < 10 tonnes 21-05-2019 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde
942-738-4 - Active Full Joint ≥ 1 to < 10 tonnes 07-12-2018 View substance registered dossier
4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride
619-800-1 - Active Intermediate Joint Intermediate use only 06-06-2019 View substance registered dossier
4-(trans-4-Propylcyclohexyl)-1-bromobenzene
485-340-1 - Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
458-850-7 - Active NONS Joint Tonnage data confidential 23-05-2018 View substance registered dossier
4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid
423-750-4 - Active NONS Individual Tonnage data confidential 11-04-2012 View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Active Full Individual ≥ 1 to < 10 tonnes 05-10-2011 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate
- - Active Full Joint Tonnage data confidential 04-12-2017 View substance registered dossier
4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
928-806-6 - Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate
431-360-0 - Active NONS Individual Tonnage data confidential 02-08-2011 View substance registered dossier
4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one
938-153-9 - Active Full Joint ≥ 10 to < 100 tonnes 27-06-2017 View substance registered dossier
4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate
451-040-4 - Active NONS Individual Tonnage data confidential 27-11-2012 View substance registered dossier
4-[bis(phenylsubstituted)substituted]phthalic acid
- - Active Full Joint ≥ 1 to < 10 tonnes 02-06-2020 View substance registered dossier
4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl
935-977-0 - Active Full Joint ≥ 0 to < 10 tonnes 16-10-2019 View substance registered dossier
4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide
925-003-2 - Active Intermediate Joint Intermediate use only 27-03-2018 View substance registered dossier
4-acetyl-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide
- - Active Intermediate Joint Intermediate use only 24-02-2022 View substance registered dossier
4-Amino-2,3-dichlorophenol
464-070-8 - Active Intermediate Joint Intermediate use only 28-09-2021 View substance registered dossier
4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide
438-910-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl
936-926-5 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy
482-430-2 - Active Full Individual ≥ 0 to < 10 tonnes 24-03-2021 View substance registered dossier
4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl
938-422-0 - Active Full Joint ≥ 0 to < 10 tonnes 13-05-2019 View substance registered dossier
4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl]
936-119-8 - Active Full Joint ≥ 1 to < 10 tonnes 07-12-2018 View substance registered dossier
4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl]
935-545-1 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-CPH
428-130-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl
921-136-5 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
4-Ethyl-3'-fluorobiphenyl
918-150-9 - Active Intermediate Joint Intermediate use only 31-03-2021 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one
908-868-0 - Active Intermediate Joint Intermediate use only 22-01-2020 View substance registered dossier
4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer
433-660-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile
936-067-6 - Active Intermediate Joint Intermediate use only 24-10-2017 View substance registered dossier
4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide
946-432-1 - Active Intermediate Individual Intermediate use only 09-01-2018 View substance registered dossier
4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine
467-100-8 - Active Full Joint ≥ 10 to < 100 tonnes 10-05-2019 View substance registered dossier
4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine
467-100-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methylaminopiperidine dihydrobromide
919-497-9 - Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
4-Phenylfluoren-9-one
- - Active Intermediate Joint Intermediate use only 04-03-2022 View substance registered dossier
4-poly(propyl), benzene sulfonic acid
919-274-6 - Active Intermediate Individual Intermediate use only 10-12-2012 View substance registered dossier
4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts.
466-670-5 - Active NONS Individual Tonnage data confidential 24-11-2010 View substance registered dossier
4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid
926-027-6 - Active Intermediate Joint Intermediate use only 08-07-2019 View substance registered dossier
493 F
437-020-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4HBAGE
437-510-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol
943-142-7 - Active Intermediate Joint Intermediate use only 08-04-2021 View substance registered dossier
5'-chloro-2'-hydroxy-3'nitro-[1,1'-biphenyl]-3-carboxylicacid.
472-740-6 - Active NONS Individual Tonnage data confidential 19-02-2009 View substance registered dossier
5,12-dihydroquinolino[2,3-b]acridine-7,14-dione and (mono and bis)-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione
700-776-7 - Active Full Joint ≥ 1 to < 10 tonnes 07-05-2013 View substance registered dossier
5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane
701-388-0 - Active Full Joint ≥ 0 to < 10 tonnes 23-09-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Propyl-tetrahydropyran-2-yl)-phenol 919-949-5 - 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde 942-738-4 - 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride 619-800-1 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride 619-800-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - 2018; 2019 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE 458-850-7 - 2018 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active 4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid 423-750-4 - 2012 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide - - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Rolic Technologies B.V. Luchthavenweg 10 5657 EB Eindhoven Netherlands Netherlands Active 4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate - - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 928-806-6 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate 431-360-0 - 2011 View substance registered dossier
Schering-Plough (Ireland) Company Avondale Co Wicklow Avondale Co. Wicklow Ireland Ireland Active 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2014 View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2015; 2017 View substance registered dossier
- - - - 4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate 451-040-4 - - View substance registered dossier
Covance Clinical Development SA 024 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 4-[bis(phenylsubstituted)substituted]phthalic acid - - 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 935-977-0 - 2019 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide 925-003-2 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-acetyl-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide - - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-Amino-2,3-dichlorophenol 464-070-8 - 2010 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-Amino-2,3-dichlorophenol 464-070-8 - 2011; 2021 View substance registered dossier
- - - - 4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide 438-910-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl 936-926-5 - - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy 482-430-2 - 2014; 2016; 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl 938-422-0 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl] 936-119-8 - 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl] 935-545-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-CPH 428-130-7 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl 921-136-5 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Ethyl-3'-fluorobiphenyl 918-150-9 - 2021 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one 908-868-0 - 2020 View substance registered dossier
- - - - 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile 936-067-6 - - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide 946-432-1 - - View substance registered dossier
[Confidential] - - - 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
- - - - 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 4-Methyl-N-[3-(triethoxysilyl)propyl]-2-pentanimine 467-100-8 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 4-methylaminopiperidine dihydrobromide 919-497-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Phenylfluoren-9-one - - 2022 View substance registered dossier
Chevron Oronite SA M/I Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France France Active 4-poly(propyl), benzene sulfonic acid 919-274-6 - 2012 View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom Active 4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts. 466-670-5 - 2010 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-{[4-(3-amino-4-sulfoanilino)-6-chloro-1,3,5-triazin-2-yl]amino}-6-[(5-carbamoyl-1-ethyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl]benzene-1,3-disulfonic acid 926-027-6 - - View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Active 493 F 437-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4HBAGE 437-510-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4‘-Ethoxy-3,2‘,3‘-trifluoro-4-pentyloxy-biphenyl-2-ol 943-142-7 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 5'-chloro-2'-hydroxy-3'nitro-[1,1'-biphenyl]-3-carboxylicacid. 472-740-6 - - View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 5,12-dihydroquinolino[2,3-b]acridine-7,14-dione and (mono and bis)-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione 700-776-7 - - View substance registered dossier
HP Inc Czech Republic s. r. o. Za Brumlovkou 5/1559 140 00 Prague Czech Republic Czech Republic Cease Manufacture 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2021 View substance registered dossier
HP Italy S.r.l. Via Donat Cattin, 5 Cernusco sul Naviglio 20063 Milano Italy Italy Active 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2018; 2021 View substance registered dossier
HP Deutschland GmbH Herrenberger Strasse 140 71034 Boeblingen Germany Germany Active 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2018; 2019; 2021 View substance registered dossier
HP Inc UK Limited Earley West 300 Thames Valley Park Drive RG6 1PT Reading United Kingdom United Kingdom No longer Valid 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2021 View substance registered dossier
HP Europe B.V. Mail Box: CV11300 Omega house, Stone Business Park ST15 0SR Stone Netherlands Netherlands Active 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2018; 2019; 2021 View substance registered dossier
HP Production Company Limited Barnhall Road Liffey Park Technology Campus . Leixlip Co.Kildare Ireland Ireland Cease Manufacture 5,5-Dimethylimidazolidine-2,4-dione, reaction products with oxirane 701-388-0 - 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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