Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 17,201 - 17,300 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
cyclopentyl methyl ether	445-090-6	5614-37-9	Active	Full	Individual	≥ 10 to < 100 tonnes	29-04-2015	View substance registered dossier
PAC-5M	445-100-9	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
reaction mass of: pentasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-3-[(E)-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonatetrisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(2-hydroxyethylsulfonyl)-phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(2-hydroxyethylsulfonyl)phenylazo]naphthalene-2,7-disulfonate	445-280-9	371921-40-3	Active	Full	Joint	≥ 1 tonnes	27-10-2022	View substance registered dossier
reaction mass of: pentasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-3-[(E)-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonatetrisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(2-hydroxyethylsulfonyl)-phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(2-hydroxyethylsulfonyl)phenylazo]naphthalene-2,7-disulfonate	445-280-9	371921-40-3	Cease Manufacture	NONS	Individual	Cease manufacture	21-07-2010	View substance registered dossier
3-ethyl-3-[(2-ethylhexyloxy)methyl]oxetane	445-460-7	-	Active	NONS	Individual	Tonnage data confidential	29-10-2012	View substance registered dossier
A reaction mixture containing the following components;A: Tetralithium[2(or 3), 9 (or 10), 16(or 17), 23 (or 24)-tetrakis (3-sulfonato-propylsulfonyl)phthalocyaninato]cuprate (II)B: Trilithium [3-(2-hyroxylpropylsulfamoyl) propylsulfonyl]tris (3-sulfonato-propylsulfonyl) phtalocyaninatocuprate(II)C: Dilithiumbis [3-(2-hydroxylpropylsulfamoyl)propylsulfonyl] bis (3-sulfonato-propylsulfonyl)phtalocyaninatcuprate (II)D: Lithiumtris [3-(2-hyroxylpropylsulfamoyl) propylsulfonyl](3-sulfonato-propylsulfonyl)phtalocyaninto] cuprate (II)E: Tetrakis [3-(2-hyroxypropylsulfamoyl)propylsulphonyl]phthalocyaninatocuprate (II)in the ratio A:B:C:D:Eca 32:42:21:5:<1	445-470-1	569316-88-7	Active	Full	Joint	≥ 10 tonnes	17-09-2015	View substance registered dossier
Mixed potassium sodium -tert-butyl-4-cyano-5-[{4-methyl-6-[(6-sulfo-1,3-benzothiazol-2-yl) (2,4,6-trimethyl-3-sulfophenyl)amino]-2-[(2,4,6-trimethyl-3-sulfophenyl)amino]pyridin-3-yl}diazenyl]-1Hpyrazol-1-yl}-1,3-benzothiazole-6-sulfonate	445-480-6	-	Active	NONS	Joint	Tonnage data confidential	29-04-2021	View substance registered dossier
LUMATION* GREEN 1302 LIGHT EMITTING POLYMER	445-490-0	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
5-tert-butyl-2-methoxybenzaldehyde	445-500-3	-	Active	Intermediate	Joint	Intermediate use only	05-12-2019	View substance registered dossier
Reaction mass of 2-hydroxy-1-{3-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one and 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one	445-510-8	-	Active	Full	Joint	≥ 10 to < 100 tonnes	09-10-2019	View substance registered dossier
Reaction mass of 2-hydroxy-1-{3-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one and 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one	445-510-8	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-540-1	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
rac-[(2R,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHYL METHANESULFONATE MONOHYDROCHLORIDE	445-550-6	155661-07-7	Cease Manufacture	Full	Joint	Cease manufacture	22-03-2019	View substance registered dossier
[No public or meaningful name is available]	445-570-5	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	Active	Intermediate	Individual	Intermediate use only	18-05-2022	View substance registered dossier
3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	Active	Full	Joint	≥ 1 tonnes	12-05-2017	View substance registered dossier
[No public or meaningful name is available]	445-600-7	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
Lithium Potassium Titanium Oxide	445-620-6	39318-30-4	Active	Full	Joint	≥ 10 tonnes	08-02-2018	View substance registered dossier
Reaction mass of 1,2-Diacetoxy-3-butene and 1,2-Dihydroxy-3-butene, monoacetate	445-630-0	-	Active	Intermediate	Joint	Intermediate use only	07-06-2016	View substance registered dossier
(1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline	445-640-5	-	Active	NONS	Individual	Tonnage data confidential	25-05-2011	View substance registered dossier
[No public or meaningful name is available]	445-660-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-670-9	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	Active	Full	Joint	≥ 10 to < 100 tonnes	24-01-2019	View substance registered dossier
7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-690-8	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-700-0	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
1,4,5,8-tetrakis(4-butylphenylamino)anthracene-9,10-dione	445-710-5	108313-21-9	Active	Full	Joint	≥ 0 to < 10 tonnes	19-11-2019	View substance registered dossier
1,4,5,8-tetrakis(4-butylphenylamino)anthracene-9,10-dione	445-710-5	108313-21-9	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-730-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
AI-0115-37	445-740-9	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	Active	Intermediate	Individual	Intermediate use only	16-04-2013	View substance registered dossier
(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
Reaction mass of 1,1'-(methylenedi-4,1-phenylene)bis(3-octadecylurea) and 1,1'-(methylenedi-4,1-phenylene)bis(3-octylurea) and 3-octadecyl-3-(4-{4-[(octylcarbamoyl)amino]benzyl}phenyl)urea	445-760-8	-	Active	Full	Joint	≥ 100 to < 1 000 tonnes	14-09-2018	View substance registered dossier
Reaction mass of 1,1'-(methylenedi-4,1-phenylene)bis(3-octadecylurea) and 1,1'-(methylenedi-4,1-phenylene)bis(3-octylurea) and 3-octadecyl-3-(4-{4-[(octylcarbamoyl)amino]benzyl}phenyl)urea	445-760-8	-	Active	Full	Individual	≥ 1 to < 10 tonnes	29-10-2012	View substance registered dossier
trans-2-isopropyl-5-carboxy-1,3-dioxane DHP OPT	445-770-2	42031-28-7	Active	Intermediate	Joint	Intermediate use only	16-11-2022	View substance registered dossier
trans-2-isopropyl-5-carboxy-1,3-dioxane DHP OPT	445-770-2	42031-28-7	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
trans-2-isopropyl-5-carboxy-1,3-dioxane DHP OPT	445-770-2	42031-28-7	Active	Intermediate	Individual	Intermediate use only	11-11-2011	View substance registered dossier
Ethyl 2-hydroxy-3-methylbut-3-enoate EVERNOTE	445-780-7	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs.	445-790-1	404362-22-7	Active	Full	Individual	≥ 10 to < 100 tonnes	11-11-2016	View substance registered dossier
REAKTIV-ROT F02-0037	445-800-4	-	Active	NONS	Joint	≥ 0 to < 10 tonnes	24-04-2020	View substance registered dossier
tetrasodium 4-amino-3,6-bis[(2,5-dimethoxy-4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]-5-hydroxynaphthalene-2,7-disulfonate	445-810-9	536737-09-4	Active	NONS	Joint	Tonnage data confidential	19-05-2017	View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	Active	Intermediate	Individual	Intermediate use only	19-06-2018	View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide IOHEXOL MELLOMPRODUKT '541'	445-830-8	31127-80-7	Active	Full	Joint	≥ 0 to < 10 tonnes	19-09-2019	View substance registered dossier
5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide IOHEXOL MELLOMPRODUKT '541'	445-830-8	31127-80-7	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
E-2952 (POLYMER ALONE)	445-840-2	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
2,2-dimethyl-4,7-dihydro-1,3-dioxepine ABTA-KETAL	445-850-7	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-860-1	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
cis-1,2-Cyclohexanedicarboxylic Acid	445-870-6	610-09-3	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
N-Decyl-4-nitrobenzamide	445-880-0	64026-19-3	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
N,N-Bis(trimethylsilyl)aminopropylmethyldiethoxysilane	445-890-5	201290-01-9	Active	Intermediate	Joint	Intermediate use only	30-10-2017	View substance registered dossier
N,N-Bis(trimethylsilyl)aminopropylmethyldiethoxysilane	445-890-5	201290-01-9	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	445-900-8	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate	445-910-2	649761-22-8	Active	Full	Joint	≥ 1 to < 10 tonnes	14-10-2016	View substance registered dossier
methyl (9-acetoxy-3,8,10-triethyl-7,8,10-trimethyl-1,5-dioxa-9-aza-spiro[5.5]undec-3-yl)octadecanoate	445-990-9	376588-17-9	Cease Manufacture	NONS	Joint	Cease manufacture	24-06-2009	View substance registered dossier
2-ethyl-N-methyl-N-(3-methylphenyl) butanamide PARADISAMIDE	446-190-2	406488-30-0	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
5-FR	446-200-5	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
Reaction mass of rel‐(4aR,8R,9bS)‐7,7,8,9,9‐PENTAMETHYL‐4,4A,5,6,7,8,9,9B‐OCTAHYDROINDENO[4,5‐d][1,3]DIOXINE and rel‐(4aR,8S,9bS)‐7,7,8,9,9‐PENTAMETHYL‐4,4A,5,6,7,8,9,9B‐OCTAHYDROINDENO[4,5‐d][1,3]DIOXINE	446-220-4	-	Active	Full	Joint	≥ 10 to < 100 tonnes	30-10-2013	View substance registered dossier
TBT-DET	446-230-9	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(1-ethoxyethoxy)cyclododecane	446-240-3	-	Active	Full	Joint	≥ 1 tonnes	03-08-2021	View substance registered dossier
(1-ethoxyethoxy)cyclododecane	446-240-3	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-260-2	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[(1,2-phenylene)bis(2R,5R-dimethylphopholane-kappaP)-(1,2,5,6-eta)-cycloocta-1,5-dienyl]rhodium(I)tetrafluoroborate [1,2-BIS((2R,5R)-DIMETHYLPHOSPHOLANO)BENZENE]-; (1,5-CYCLOOCTADIENE) RHODIUM(I) TETRAFLUOROBORATE	446-280-1	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-400-2	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-410-7	-	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
4-[4-(diethylamino)benzylidene]-5-ethoxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one	446-420-1	474044-10-5	Active	Full	Individual	≥ 1 to < 10 tonnes	17-11-2021	View substance registered dossier
4-[4-(diethylamino)benzylidene]-5-ethoxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one	446-420-1	474044-10-5	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-430-6	-	Active	NONS	Joint	Tonnage data confidential	24-06-2009	View substance registered dossier
[No public or meaningful name is available]	446-440-0	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-450-5	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
zinc salts, fatty acids, C16-18 and C18 unsaturated, branched and linear	446-470-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
Thiosulfuric acid(H2S2O3),S-[2-[[3-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl]ester, calcium salt (2:1)	446-480-9	34644-00-3	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-490-3	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-500-6	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-510-0	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-520-5	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
[No public or meaningful name is available]	446-540-4	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
[No public or meaningful name is available]	446-550-9	216970-21-7	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
4,6-Dichloro-5-fluoropyrimidine	446-560-3	-	Active	Intermediate	Joint	Intermediate use only	30-06-2022	View substance registered dossier
1-Hydroxycyclohexanecarboxylic acid ethyl ester	446-570-8	-	No longer Valid	NONS	Individual	No longer valid	03-01-2011	View substance registered dossier
1-Hydroxycyclohexanecarboxylic acid ethyl ester	446-570-8	-	Active	Intermediate	Joint	Intermediate use only	28-03-2013	View substance registered dossier
[No public or meaningful name is available]	446-590-7	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
[No public or meaningful name is available]	446-610-4	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
2-Chloro-1-(1-chlorocyclopropyl)-1-ethanone	446-620-9	-	Active	Intermediate	Joint	Intermediate use only	28-05-2021	View substance registered dossier
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile	446-630-3	181587-01-9	Active	Full	Joint	≥ 100 to < 1 000 tonnes	24-08-2021	View substance registered dossier
ucb 22060	446-640-8	-	Active	Full	Joint	≥ 100 to < 1 000 tonnes	21-08-2018	View substance registered dossier
2-(2-oxopyrrolidin-1-yl)butyramide	446-650-2	-	Active	Full	Individual	≥ 100 to < 1 000 tonnes	20-05-2016	View substance registered dossier
2-(2-oxopyrrolidin-1-yl)butyramide	446-650-2	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	01-10-2012	View substance registered dossier
7 ALPHA	446-790-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
2-(undec-10-enoylamino)-3-phenylpropanoic acid	446-800-7	175357-18-3	Active	Full	Joint	≥ 1 to < 10 tonnes	22-10-2019	View substance registered dossier
1-butoxy-2,3-difluorobenzene 1-BUTOXY-2,3-DIFLUORBENZOL; BUPHOL	446-810-1	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
1-butoxy-2,3-difluorobenzene 1-BUTOXY-2,3-DIFLUORBENZOL; BUPHOL	446-810-1	-	Active	Intermediate	Joint	Intermediate use only	20-12-2019	View substance registered dossier
TCO	446-820-6	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
2-(hydroxymethyl)oxolane-3,4-diol; 5-{[2,3,4,5-tetrahydroxy-6-(xenoniooxy)hexyl]oxy}pentane-1,2,3,4-tetrol; pentane-1,2,3,4,5-pentol	446-990-1	-	Active	Full	Joint	≥ 100 to < 1 000 tonnes	23-01-2019	View substance registered dossier
THBP	447-000-0	-	Cease Manufacture	NONS	Individual	Cease manufacture	15-11-2012	View substance registered dossier
Nonylbenzoate, branched and linear ISONONYLBENZOAT	447-010-5	670241-72-2	Active	Full	Individual	≥ 100 to < 1 000 tonnes	29-03-2022	View substance registered dossier
[No public or meaningful name is available]	447-050-3	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
N-(carboxymethyl)-3-[(2Z)-docos-2-enoylamino]-N,N-dimethylpropan-1-aminium	447-060-8	-	Active	Full	Joint	≥ 100 to < 1 000 tonnes	25-02-2021	View substance registered dossier
N-(carboxymethyl)-3-[(2Z)-docos-2-enoylamino]-N,N-dimethylpropan-1-aminium	447-060-8	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier

Showing 17,201 - 17,300 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	cyclopentyl methyl ether	445-090-6	5614-37-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	PAC-5M	445-100-9	-	-	View substance registered dossier
Specialty Electronic Materials Netherlands BV OR-1	Baanhoekweg 22 3313 LA Dordrecht Netherlands	Netherlands	Cease Manufacture	PAC-5M	445-100-9	-	2020	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	reaction mass of: pentasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-3-[(E)-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonatetrisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(2-hydroxyethylsulfonyl)-phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(2-hydroxyethylsulfonyl)phenylazo]naphthalene-2,7-disulfonate	445-280-9	371921-40-3	2022	View substance registered dossier
Archroma France, SAS	Rue du Flottage 60350 Trosly-Breuil France	France	Cease Manufacture	reaction mass of: pentasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-3-[(E)-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonatetrisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(2-hydroxyethylsulfonyl)-phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(2-hydroxyethylsulfonyl)phenylazo]naphthalene-2,7-disulfonate	445-280-9	371921-40-3	2022	View substance registered dossier
Archroma France, SAS - OR	Rue du Flottage, BP 1 60350 Trosly-Breuil France	France	Cease Manufacture	reaction mass of: pentasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-3-{(E)-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,tetrasodium 4-amino-5-hydroxy-6-{(E)-2-sulfonato-4-[2-(sulfonatooxy)ethylsulfonyl]phenylazo}-3-[(E)-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonatetrisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(2-hydroxyethylsulfonyl)-phenylazo]-6-[(E)-2-sulfonato-4-(vinylsulfonyl)phenylazo]naphthalene-2,7-disulfonate,trisodium 4-amino-5-hydroxy-3-[(E)-4-(vinylsulfonyl)phenylazo]-6-[(E)-2-sulfonato-4-(2-hydroxyethylsulfonyl)phenylazo]naphthalene-2,7-disulfonate	445-280-9	371921-40-3	2019	View substance registered dossier
SCAS Europe S.A./N.V.	Leonardo Da Vincilaan 19 B-1831 Diegem Belgium	Belgium	Active	3-ethyl-3-[(2-ethylhexyloxy)methyl]oxetane	445-460-7	-	2012	View substance registered dossier
[Confidential]	-	-	-	A reaction mixture containing the following components;A: Tetralithium[2(or 3), 9 (or 10), 16(or 17), 23 (or 24)-tetrakis (3-sulfonato-propylsulfonyl)phthalocyaninato]cuprate (II)B: Trilithium [3-(2-hyroxylpropylsulfamoyl) propylsulfonyl]tris (3-sulfonato-propylsulfonyl) phtalocyaninatocuprate(II)C: Dilithiumbis [3-(2-hydroxylpropylsulfamoyl)propylsulfonyl] bis (3-sulfonato-propylsulfonyl)phtalocyaninatcuprate (II)D: Lithiumtris [3-(2-hyroxylpropylsulfamoyl) propylsulfonyl](3-sulfonato-propylsulfonyl)phtalocyaninto] cuprate (II)E: Tetrakis [3-(2-hyroxypropylsulfamoyl)propylsulphonyl]phthalocyaninatocuprate (II)in the ratio A:B:C:D:Eca 32:42:21:5:<1	445-470-1	569316-88-7	-	View substance registered dossier
Fujifilm Europe GmbH (OR1)	Balcke-Dürr-Allee 6 40882 Ratingen Germany	Germany	Active	Mixed potassium sodium -tert-butyl-4-cyano-5-[{4-methyl-6-[(6-sulfo-1,3-benzothiazol-2-yl) (2,4,6-trimethyl-3-sulfophenyl)amino]-2-[(2,4,6-trimethyl-3-sulfophenyl)amino]pyridin-3-yl}diazenyl]-1Hpyrazol-1-yl}-1,3-benzothiazole-6-sulfonate	445-480-6	-	2021	View substance registered dossier
Fujifilm Imaging Colorants Limited	Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom	United Kingdom	No longer Valid	Mixed potassium sodium -tert-butyl-4-cyano-5-[{4-methyl-6-[(6-sulfo-1,3-benzothiazol-2-yl) (2,4,6-trimethyl-3-sulfophenyl)amino]-2-[(2,4,6-trimethyl-3-sulfophenyl)amino]pyridin-3-yl}diazenyl]-1Hpyrazol-1-yl}-1,3-benzothiazole-6-sulfonate	445-480-6	-	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	LUMATION* GREEN 1302 LIGHT EMITTING POLYMER	445-490-0	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	5-tert-butyl-2-methoxybenzaldehyde	445-500-3	-	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	5-tert-butyl-2-methoxybenzaldehyde	445-500-3	-	2019	View substance registered dossier
BCH Brühl - Chemikalien Handel GmbH	Immendorfer Str. 8 50321 Brühl NRW Germany	Germany	Active	Reaction mass of 2-hydroxy-1-{3-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one and 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one	445-510-8	-	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	Reaction mass of 2-hydroxy-1-{3-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one and 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one	445-510-8	-	2017	View substance registered dossier
-	-	-	-	Reaction mass of 2-hydroxy-1-{3-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one and 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one	445-510-8	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-540-1	-	-	View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company	Little Island County NA Cork Ireland	Ireland	Cease Manufacture	rac-[(2R,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHYL METHANESULFONATE MONOHYDROCHLORIDE	445-550-6	155661-07-7	2022	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-570-5	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Cease Manufacture	3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	2021	View substance registered dossier
Thermo Fisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Cork Ireland	Ireland	Active	3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	[No public or meaningful name is available]	445-600-7	-	-	View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR19	Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands	Netherlands	Cease Manufacture	Lithium Potassium Titanium Oxide	445-620-6	39318-30-4	2017	View substance registered dossier
Hebron, S.A.	Hebron, S.A. C/ Girona , 20 08120 La Llagosta Barcelona Spain	Spain	Active	Lithium Potassium Titanium Oxide	445-620-6	39318-30-4	2017	View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR62	Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands	Netherlands	Active	Lithium Potassium Titanium Oxide	445-620-6	39318-30-4	2017; 2018	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	Reaction mass of 1,2-Diacetoxy-3-butene and 1,2-Dihydroxy-3-butene, monoacetate	445-630-0	-	2010; 2016	View substance registered dossier
Astellas Ireland Co.Ltd	Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland	Ireland	Active	(1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline	445-640-5	-	2011	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-660-4	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority.	-	-	Active	[No public or meaningful name is available]	445-670-9	-	-	View substance registered dossier
Chemosyntha BV	Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium	Belgium	Active	7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	2017	View substance registered dossier
[Confidential]	-	-	-	7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	-	View substance registered dossier
-	-	-	-	7-methyl-2H-1,3-benzoxazine-2,4(3H)-dione	445-680-3	24088-77-5	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-690-8	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	[No public or meaningful name is available]	445-700-0	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-700-0	-	-	View substance registered dossier
DOW BENELUX B.V.	Postbus 48 4530 AA Terneuzen Netherlands	Netherlands	Active	1,4,5,8-tetrakis(4-butylphenylamino)anthracene-9,10-dione	445-710-5	108313-21-9	2014; 2019	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Cease Manufacture	1,4,5,8-tetrakis(4-butylphenylamino)anthracene-9,10-dione	445-710-5	108313-21-9	2012	View substance registered dossier
CS Regulatory IRL Ltd 2M-6	Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland	Ireland	Active	1,4,5,8-tetrakis(4-butylphenylamino)anthracene-9,10-dione	445-710-5	108313-21-9	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	445-730-4	-	-	View substance registered dossier
Kraton Chemical S.A.S.	262 Rue Jean-Jaures - BP 8405 FR-79024 Niort - Cedex 4 France	France	Active	AI-0115-37	445-740-9	-	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	2013	View substance registered dossier
Zach System	ZI La Croix Cadeau 49242 Avrillé France	France	Active	(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	-	View substance registered dossier
TÜV SÜD Industrie Service GmbH (13)	Westendstrasse 199 80686 Munich Germany	Germany	Active	Reaction mass of 1,1'-(methylenedi-4,1-phenylene)bis(3-octadecylurea) and 1,1'-(methylenedi-4,1-phenylene)bis(3-octylurea) and 3-octadecyl-3-(4-{4-[(octylcarbamoyl)amino]benzyl}phenyl)urea	445-760-8	-	2016; 2018	View substance registered dossier
IMPERATOR	340 RUE DE BREUZE BP 59 59780 BAISIEUX France	France	Active	Reaction mass of 1,1'-(methylenedi-4,1-phenylene)bis(3-octadecylurea) and 1,1'-(methylenedi-4,1-phenylene)bis(3-octylurea) and 3-octadecyl-3-(4-{4-[(octylcarbamoyl)amino]benzyl}phenyl)urea	445-760-8	-	2015; 2016; 2018	View substance registered dossier
[Confidential]	-	-	-	Reaction mass of 1,1'-(methylenedi-4,1-phenylene)bis(3-octadecylurea) and 1,1'-(methylenedi-4,1-phenylene)bis(3-octylurea) and 3-octadecyl-3-(4-{4-[(octylcarbamoyl)amino]benzyl}phenyl)urea	445-760-8	-	-	View substance registered dossier
guerbet	BP57400 95743 roissy cdg cedex France	France	Active	trans-2-isopropyl-5-carboxy-1,3-dioxane	445-770-2	42031-28-7	-	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	trans-2-isopropyl-5-carboxy-1,3-dioxane	445-770-2	42031-28-7	2022	View substance registered dossier
Simafex	16 av des fours à chaux 17230 Marans France	France	Active	trans-2-isopropyl-5-carboxy-1,3-dioxane	445-770-2	42031-28-7	-	View substance registered dossier
[Confidential]	-	-	-	trans-2-isopropyl-5-carboxy-1,3-dioxane	445-770-2	42031-28-7	-	View substance registered dossier
-	-	-	-	Ethyl 2-hydroxy-3-methylbut-3-enoate	445-780-7	-	-	View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH	Immermannstr.13 40210 Duesseldorf Germany	Germany	Active	1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs.	445-790-1	404362-22-7	2014; 2016	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Active	REAKTIV-ROT F02-0037	445-800-4	-	2011; 2020	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Active	tetrasodium 4-amino-3,6-bis[(2,5-dimethoxy-4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]-5-hydroxynaphthalene-2,7-disulfonate	445-810-9	536737-09-4	2014; 2017	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	No longer Valid	(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	2022	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate	445-820-3	-	2021	View substance registered dossier
Interpharma Praha	Komoranska 955 14300 Prague Czech Republic	Czech Republic	Active	5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide	445-830-8	31127-80-7	-	View substance registered dossier
Justesa Imagen S.A.U.	Avenida de San Pablo 27 28823 Coslada Madrid Spain	Spain	Active	5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide	445-830-8	31127-80-7	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Norwegian competent national authority.	-	-	No longer Valid	5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide	445-830-8	31127-80-7	2022	View substance registered dossier
Reichhold AS	Øraveien 8/19 N-1630 Gamle Fredrikstad Ostfold Norway	Norway	Active	E-2952 (POLYMER ALONE)	445-840-2	-	-	View substance registered dossier
Borregaard AS	Hjalmar Wessels vei 6 1701 Sarpsborg Norway	Norway	Active	2,2-dimethyl-4,7-dihydro-1,3-dioxepine	445-850-7	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	[No public or meaningful name is available]	445-860-1	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	cis-1,2-Cyclohexanedicarboxylic Acid	445-870-6	610-09-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	N-Decyl-4-nitrobenzamide	445-880-0	64026-19-3	-	View substance registered dossier
Shin-Etsu Silicones Europe BV - Importer	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	N,N-Bis(trimethylsilyl)aminopropylmethyldiethoxysilane	445-890-5	201290-01-9	2017	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	N,N-Bis(trimethylsilyl)aminopropylmethyldiethoxysilane	445-890-5	201290-01-9	-	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	[No public or meaningful name is available]	445-900-8	-	2021	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	[No public or meaningful name is available]	445-900-8	-	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Active	(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate	445-910-2	649761-22-8	2010; 2011; 2012; 2014	View substance registered dossier
Swords Laboratories Unlimited Company	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate	445-910-2	649761-22-8	2010; 2012; 2014; 2016	View substance registered dossier
BASF Italia S.p.A. OR15	Via Marconato 8 20811 Cesano Maderno Italy	Italy	Cease Manufacture	methyl (9-acetoxy-3,8,10-triethyl-7,8,10-trimethyl-1,5-dioxa-9-aza-spiro[5.5]undec-3-yl)octadecanoate	445-990-9	376588-17-9	2019	View substance registered dossier
BASF Italia S.p.A.	Via Marconato 8 20811 Cesano Maderno Italy	Italy	Cease Manufacture	methyl (9-acetoxy-3,8,10-triethyl-7,8,10-trimethyl-1,5-dioxa-9-aza-spiro[5.5]undec-3-yl)octadecanoate	445-990-9	376588-17-9	2019	View substance registered dossier
Givaudan Iberica SA	Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain	Spain	Active	2-ethyl-N-methyl-N-(3-methylphenyl) butanamide	446-190-2	406488-30-0	-	View substance registered dossier
-	-	-	-	5-FR	446-200-5	-	-	View substance registered dossier
IFF Benicarlo, S.L.	Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain	Spain	Active	Reaction mass of rel‐(4aR,8R,9bS)‐7,7,8,9,9‐PENTAMETHYL‐4,4A,5,6,7,8,9,9B‐OCTAHYDROINDENO[4,5‐d][1,3]DIOXINE and rel‐(4aR,8S,9bS)‐7,7,8,9,9‐PENTAMETHYL‐4,4A,5,6,7,8,9,9B‐OCTAHYDROINDENO[4,5‐d][1,3]DIOXINE	446-220-4	-	2013	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	TBT-DET	446-230-9	-	-	View substance registered dossier
-	-	-	-	TBT-DET	446-230-9	-	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(1-ethoxyethoxy)cyclododecane	446-240-3	-	2011; 2012; 2021	View substance registered dossier
FIRMENICH GRASSE SAS OR 2	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(1-ethoxyethoxy)cyclododecane	446-240-3	-	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(1-ethoxyethoxy)cyclododecane	446-240-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-260-2	-	-	View substance registered dossier
Robinson Brothers Ltd	Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom	United Kingdom	No longer Valid	[No public or meaningful name is available]	446-260-2	-	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	[(1,2-phenylene)bis(2R,5R-dimethylphopholane-kappaP)-(1,2,5,6-eta)-cycloocta-1,5-dienyl]rhodium(I)tetrafluoroborate	446-280-1	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	[No public or meaningful name is available]	446-400-2	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-410-7	-	-	View substance registered dossier
Mitsubishi_Chemical_Europe_GmbH	Willstätterstraße 30 40549 Düsseldorf Germany	Germany	Active	4-[4-(diethylamino)benzylidene]-5-ethoxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one	446-420-1	474044-10-5	2012; 2021	View substance registered dossier
-	-	-	-	4-[4-(diethylamino)benzylidene]-5-ethoxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one	446-420-1	474044-10-5	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	[No public or meaningful name is available]	446-430-6	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-430-6	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-440-0	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	[No public or meaningful name is available]	446-440-0	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-450-5	-	-	View substance registered dossier
Kraton Chemical S.A.S.	262 Rue Jean-Jaures - BP 8405 FR-79024 Niort - Cedex 4 France	France	Active	zinc salts, fatty acids, C16-18 and C18 unsaturated, branched and linear	446-470-4	-	-	View substance registered dossier
-	-	-	-	Thiosulfuric acid(H2S2O3),S-[2-[[3-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl]ester, calcium salt (2:1)	446-480-9	34644-00-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	[No public or meaningful name is available]	446-490-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-490-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	[No public or meaningful name is available]	446-500-6	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-500-6	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-510-0	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-520-5	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	[No public or meaningful name is available]	446-520-5	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	[No public or meaningful name is available]	446-540-4	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-540-4	-	-	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	446-550-9	216970-21-7	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	[No public or meaningful name is available]	446-550-9	216970-21-7	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4,6-Dichloro-5-fluoropyrimidine	446-560-3	-	2010; 2022	View substance registered dossier
DOW CHEMICAL COMPANY LTD	Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom	United Kingdom	No longer Valid	1-Hydroxycyclohexanecarboxylic acid ethyl ester	446-570-8	-	2021	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	1-Hydroxycyclohexanecarboxylic acid ethyl ester	446-570-8	-	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	1-Hydroxycyclohexanecarboxylic acid ethyl ester	446-570-8	-	2010; 2013	View substance registered dossier
Shin-Etsu Silicones Europe BV	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	[No public or meaningful name is available]	446-590-7	-	-	View substance registered dossier
Shin-Etsu Silicones Europe BV - Importer	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	[No public or meaningful name is available]	446-590-7	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	[No public or meaningful name is available]	446-610-4	-	-	View substance registered dossier
Shin-Etsu Silicones Europe BV - Importer	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	[No public or meaningful name is available]	446-610-4	-	-	View substance registered dossier
Shin-Etsu Silicones Europe BV	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	[No public or meaningful name is available]	446-610-4	-	-	View substance registered dossier
Wacker Chemie AG	Hanns-Seidel-Platz 4 81737 Muenchen Germany	Germany	Cease Manufacture	2-Chloro-1-(1-chlorocyclopropyl)-1-ethanone	446-620-9	-	2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-Chloro-1-(1-chlorocyclopropyl)-1-ethanone	446-620-9	-	2010; 2012; 2021	View substance registered dossier
CABB Oy	Kemirantie 1 FI-67701 Kokkola Finland	Finland	Active	5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile	446-630-3	181587-01-9	2012; 2013	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile	446-630-3	181587-01-9	2010; 2013; 2021	View substance registered dossier
UCB Pharma S.A.(Belgium)	Allée de la recherche, 60 1070 Brussels Belgium	Belgium	Active	ucb 22060	446-640-8	-	2015; 2018	View substance registered dossier
UCB Pharma S.A.(Belgium)	Allée de la recherche, 60 1070 Brussels Belgium	Belgium	Active	2-(2-oxopyrrolidin-1-yl)butyramide	446-650-2	-	2013; 2016	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	2-(2-oxopyrrolidin-1-yl)butyramide	446-650-2	-	2017	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	7 ALPHA	446-790-4	-	-	View substance registered dossier
Givaudan-Lavirotte	56 rue paul Cazeneuve 69008 Lyon France	France	Active	2-(undec-10-enoylamino)-3-phenylpropanoic acid	446-800-7	175357-18-3	2018	View substance registered dossier
[Confidential]	-	-	-	2-(undec-10-enoylamino)-3-phenylpropanoic acid	446-800-7	175357-18-3	-	View substance registered dossier
seppic sa	50 boulevard National CS 90020 92257 La Garenne Colombes ile de france France	France	Active	2-(undec-10-enoylamino)-3-phenylpropanoic acid	446-800-7	175357-18-3	2010; 2012; 2018	View substance registered dossier
-	-	-	-	1-butoxy-2,3-difluorobenzene	446-810-1	-	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	1-butoxy-2,3-difluorobenzene	446-810-1	-	2013; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	TCO	446-820-6	-	-	View substance registered dossier
seppic sa	50 boulevard National CS 90020 92257 La Garenne Colombes ile de france France	France	Active	2-(hydroxymethyl)oxolane-3,4-diol; 5-{[2,3,4,5-tetrahydroxy-6-(xenoniooxy)hexyl]oxy}pentane-1,2,3,4-tetrol; pentane-1,2,3,4,5-pentol	446-990-1	-	2010; 2014; 2015; 2017; 2018	View substance registered dossier
[Confidential]	-	-	-	2-(hydroxymethyl)oxolane-3,4-diol; 5-{[2,3,4,5-tetrahydroxy-6-(xenoniooxy)hexyl]oxy}pentane-1,2,3,4-tetrol; pentane-1,2,3,4,5-pentol	446-990-1	-	-	View substance registered dossier
Merck Performance Materials GmbH	Rheingaustrasse 190-196 65203 Wiesbaden Germany	Germany	Cease Manufacture	THBP	447-000-0	-	2019	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	Nonylbenzoate, branched and linear	447-010-5	670241-72-2	2011; 2012; 2019; 2022	View substance registered dossier
-	-	-	-	[No public or meaningful name is available]	447-050-3	-	-	View substance registered dossier
RHODIA OPERATIONS - 50	52 rue de la Haie Coq 93308 AUBERVILLIERS France	France	Active	N-(carboxymethyl)-3-[(2Z)-docos-2-enoylamino]-N,N-dimethylpropan-1-aminium	447-060-8	-	2020; 2021	View substance registered dossier
RHODIA OPERATIONS	52 rue de la Haie Coq 93300 AUBERVILLIERS France	France	Active	N-(carboxymethyl)-3-[(2Z)-docos-2-enoylamino]-N,N-dimethylpropan-1-aminium	447-060-8	-	2011; 2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	N-(carboxymethyl)-3-[(2Z)-docos-2-enoylamino]-N,N-dimethylpropan-1-aminium	447-060-8	-	-	View substance registered dossier

Showing 17,201 - 17,300 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.