Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.


REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

No results were found
401-200-4 85491-26-5 Cease Manufacture Full Joint Cease manufacture 29-10-2012 View substance registered dossier
212-472-7 821-06-7 Cease Manufacture Intermediate Joint Cease manufacture 18-05-2018 View substance registered dossier
410-980-5 112704-51-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
230-603-6 7216-56-0 Cease Manufacture Full Joint Cease manufacture 17-04-2018 View substance registered dossier
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride
219-823-3 2544-13-0 Cease Manufacture Intermediate Joint Cease manufacture 03-12-2013 View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
406-960-0 77497-97-3 Cease Manufacture Intermediate Individual Cease manufacture 04-10-2012 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (chloromethyl)bis(4-fluorophenyl)methylsilane 401-200-4 85491-26-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2016 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2017 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2015 View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2021 View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Cease Manufacture (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal 410-980-5 112704-51-5 2018 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (E,Z)-2,6-dimethylocta-2,4,6-triene 230-603-6 7216-56-0 2021 View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-1,1-diphenyl-1,2-propanediol 443-220-6 46755-94-6 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Cease Manufacture (S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride 219-823-3 2544-13-0 2022 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2017 View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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