Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4,4'-bis(2-methyl-2-(4-methylphenyl)-1-propionyl)diphenylsulfide
ESACURE L 244
415-410-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol
701-072-2 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 28-10-2021 View substance registered dossier
4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol
701-276-1 - Cease Manufacture Full Joint Cease manufacture 13-02-2019 View substance registered dossier
4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane]
427-620-8 - Active NONS Joint Tonnage data confidential 05-09-2019 View substance registered dossier
4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate
951-696-6 - Active Full Joint ≥ 1 to < 10 tonnes 22-02-2021 View substance registered dossier
4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid
948-054-2 - Active Full Joint ≥ 1 to < 10 tonnes 21-10-2019 View substance registered dossier
4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide
449-920-8 - Active NONS Individual Tonnage data confidential 16-12-2010 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt
445-080-1 - No longer Valid NONS Individual No longer valid 24-11-2010 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - 4,4'-bis(2-methyl-2-(4-methylphenyl)-1-propionyl)diphenylsulfide 415-410-9 - - View substance registered dossier
DOW ITALIA S.R.L. Via F. Albani 65 20148 Milano Italy Italy Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2019 View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2012; 2014; 2016; 2017; 2019; 2021 View substance registered dossier
DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH Buetzflether Sand 2 D-21683 Stade Germany Germany Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - - View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
Nisso Chemical Europe GmbH Berliner Allee 42 40212 Düsseldorf Germany Germany Active 4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane] 427-620-8 - 2011; 2014 View substance registered dossier
Nisso Chemical Europe Berliner Allee 42 40212 Duesseldorf Germany Germany Active 4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane] 427-620-8 - 2011; 2019 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate 951-696-6 - - View substance registered dossier
[Confidential] - - - 4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate 951-696-6 - - View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid 948-054-2 - 2019 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide 449-920-8 - 2010 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt 445-080-1 - 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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